张大伟， 教授，博士生导师，生物学系系主任
联系方式：zhdawei@scu.edu.cn, yuanmiao1892@163.com
简历：★ 2004年9月—2008年7月： 四川大学； 本科 专业：生物科学
★ 2008年9月—2013年6月： 四川大学；硕博连读 专业：植物学
★ 2011年10月—2013年10月：爱荷华州立大学（美国）； 国家公派留学生联合培养
★ 2013年7月—2018年9月：四川大学生命科学学院，副研究员，博士生导师（破格）
★ 2018年7月—2019年7月：成都市高新区生物产业发展局企业服务处副处长（挂职）
★ 2018年10月—至今：四川大学生命科学学院，教授，博士生导师
研究方向及主要科研项目：
主要从事植物BR信号途径，光合作用和抗氰呼吸方面的研究工作。研究内容主要阐释抗氰呼吸交替氧化酶AOX对光信号的响应，以及AOX对叶绿素合成和光合作用的影响。研究BR信号途径重要调控因子，揭示BR信号调控基因表达以及调控植物生物/非生物胁迫抗性的分子机理。相关成果在Developmental Cell，New Phytologist, Plos Genetics，Plant Journal，Plant Biotechnology Journal等期刊发表论文70余篇。获得教育部学术新人奖基金资助，主持国家自然基金青年基金，国家自然基金面上项目2项，四川省应用基础研究计划项目，四川大学优秀青年项目，四川大学青年科学技术带头人培育项目，参与国家重点基础研究发展计划（973计划）项目，国家自然基金重点项目，面上项目，教育部博士点优先资助领域基金项目。第十二批四川省学术与技术带头人后备人选，川大双百人才B类，2020年度川大学术新人奖。BioCell和《生物学杂志》编委。
近五年主要科研成果(#第一作者，*通讯作者）：
1. Tan Wenrong ^#, Han Qing ^#, Li Yan ^#, Yang Feng, Li Jiafeng, Li Pengxu,Xu Xiumei, Lin Honghui, Zhang Dawei*.A HAT1-DELLA signaling module regulates trichome initiation and leaf growth by achieving GA homeostasis. New Phytologist.(accepted, DOI: 10.1111/nph.17422)
2. Zhang Dawei^#,*, Tan Wenrong^#, Yang Feng, Han Qing, Deng Xingguang, Guo Hongqing, Liu Baohui, Yin Yanhai, Lin Honghui*. A BIN2-GLK1 signaling module integrates brassinosteroid and light signaling to repress chloroplast development in the dark. Developmental Cell. 2021, 56: 1-15.
3. Li Taotao, Lei Wei, He Ruiyuan, Tang Xiaoya, Han Jifu, Zou Lijuan, Yin Yanhai, Lin Honghui*, Zhang Dawei*. Brassinosteroids regulate root meristem development by mediating BIN2-UPB1 module in Arabidopsis. PLOS Genetics. 2020, 16(7): e**.
4. Li Taotao^#, Kang Xinke^#, Lei Wei, Yao Xiuhong, Zou Lijuan, Zhang Dawei*, Lin Honghui*. SHY2 as a node in the regulation of root meristem development by auxin, brassinosteroids, and cytokinin. Journal of Integrative Plant Biology. 2020, 62:1500-1517.
5. Lei Wei, Li Yan, Yao Xiuhong, Qiao Kang, Wei Lin, Liu Baohui, Zhang Dawei*, Lin Honghui*. NAP is involved in GA?mediated chlorophyll degradation and leaf senescence by interacting with DELLAs in Arabidopsis, Plant Cell Reports, 2020, 39(1):75-87.
6. Li Taotao, Kang Xinke, Wei Lin, Zhang Dawei*, Lin Honghui*. A gain-of-function mutation Brassinosteroid-insensitive 2 alters Arabidopsis floral organ development by altering auxin levels. Plant Cell Reports, 2020, 39(2):259-271.
7. Zheng Ting, Li Yanling, Lei Wei, Qiao Kang, Liu Baohui, Zhang Dawei*, Lin Honghui*. SUMO E3 Ligase SIZ1 stabilizes MYB75 to regulate anthocyanin accumulation under high light conditions in Arabidopsis. Plant Science, 2020, 292:110355.
8. Xiong Jiawei^#, He Ruiyuan^#, Yang Feng, Zou Lijuan, Yi Kexian, Lin Honghui, Zhang Dawei*. Brassinosteroids is involved in ethylene‐induced Pst DC3000 resistance in Nicotianabenthamiana. Plant Biology, 2020, 22;309-316.
9. Li Taotao, Li Bingbing, Wang Lianzhe, Xie, Zhaohui, Wang Xiaotao, Zou Lijuan, Zhang Dawei*, Lin Honghui*.Phytochrome-interacting factor 4 (PIF4) inhibits expression of SHORT HYPOCOTYL 2 (SHY2) to promote hypocotyl growth during shade avoidance in Arabidopsis. Biochemical and Biophysical Research Communications, 2020, doi: 10.1016/j.bbrc.2020.10.088.
10. Zheng Ting^#, Tan Wen-Rong, Yang Huan, Zhang Li-E, Li Tao-Tao, Liu Bao-Hui, Zhang Da-Wei ^#,*, Lin Hong-Hui*. Regulation of anthocyanin accumulation via MYB75/HAT1/TPL-mediated transcriptional repression. PLOS Genetics. 2019, 15(3):e**.
11. Zou Lijuan, Yang Feng, Ma Yonghong, Wu Qinggui, Yi Kexian*, Zhang Dawei*. Transcription factor WRKY30 mediates resistance to Cucumber mosaic virus in Arabidopsis. Biochemical and Biophysical Research Communications, 2019, 517(1):118-124.
12. Zhang Li’e^#, Han Qing^#, Xiong Jiawei, Zheng Ting, Han Jifu, Zhou Huanbin, Lin Honghui, Yin Yanhai, Zhang Dawei*. Sumoylation of BRI1-EMS-SUPPRESSOR 1 (BES1) by the SUMO E3 Ligase SIZ1 Negatively Regulates Brassinosteroids Signaling in Arabidopsis thaliana, Plant and Cell Physiology, 2019,60(10):2282-2292.
13. Li Taotao, Yang Shiyan, Kang Xinke, Lei Wei, Qiao Kang, Zhang Dawei*, Lin Honghui*. The bHLH transcription factor gene AtUPB1 regulates growth by mediating cell cycle progression in Arabidopsis, Biochemical and Biophysical Research Communications 2019, 518(3):565-572.
14. Tan Wen-Rong^#, Zhang Da-Wei ^#,*, Zhou Hua-Peng^#, Zheng Ting, Yin Yan-Hai, Lin Hong-Hui*. Transcription factor HAT1 is a substrate of SnRK2.3 Kinase and negatively regulates ABA synthesis and signaling in Arabidopsis responding to drought. PLOS Genetics. 2018, 14(4):e**
15. Zhu Tong^#, Zou Li-Juan^#, Li Yan^#, Yao Xiu-Hong, Xu Fei, Deng Xing-Guang, Zhang Da-Wei*, Lin Hong-Hui*. Mitochondrial alternative oxidase dependent autophagy involved in ethylene-mediated drought tolerance in Solanum lycopersicum. Plant Biotechnology Journal. 2018, 16(12):2063-2076.
16. Zou Li-Juan^#, Deng Xing-Guang^#, Zhang Li-e, Zhu Tong, Tan Wen-Rong, Muhammad Arfan, Zhang Chao, Zhang Da-Wei*, Lin Hong-Hui*. Nitric oxide as a signaling molecule in brassinosteroid-mediated virus resistance to Cucumber mosaic virus in Arabidopsis thaliana. Physiologia Plantarum. 2018, 163(2):196-210.
17. Zhu Lijun, Deng Xingguang, Zou Lijuan, Li Pengxu, Wu Junqiang, Zhang Dawei*, Lin Hong-Hui*. Celastrol, produced by TripterygiumwilfordiiHook F. enhances defense response in cucumber seedlings against diverse environmental stresses. Journal of Plant Biology. 2017, 60:82-92.
18. Deng Xing-Guang ^#, Zhu Tong ^#, Zou Li-Juan, Han Xue-Ying, Xi De-Hui, Zhang Da-Wei ^#,*, Lin Hong-Hui*. Orchestration of hydrogen peroxide and nitric oxide in brassinosteroids mediated systemic virus resistance in Nicotiana benthamiana. Plant Journal. 2016. 85(4): 478-493.
19. Zhang Da-Wei^#, Yuan Shu^#, Xu Fei^#, Zhu Feng, Yuan Ming, Ye Hua-Xun, Guo Hong-Qing, Lv Xin, Yin Yan-Hai, Lin Hong-Hui*. 2015. Light intensity affects chlorophyll synthesis during greening process by metabolite signal from mitochondrial alternative oxidase in Arabidopsis. Plant Cell and Environment, 2016, 39(1): 12-25.
20. Deng Xing-Guang^#, Zhu Tong, Peng Xing-Ji, Xi De-Hui, Guo Hong-Qing, Yin Yan-Hai, Zhang Da-Wei ^#,*, Lin Hong-Hui*. Role of brassinosteroid signaling in modulating Tobacco mosaic virus resistance in Nicotiana benthamiana. Scientific reports, 2016, 6: Article number: 20579.
21. Zhu Tong^#, Deng Xing-Guang^#, Zhou Xue, Zhu Li-Sha, Zou Li-Juan, Li Peng-Xu, Zhang Da-Wei*, Lin Hong-Hui*. Ethylene and hydrogen peroxide are involved in brassinosteroid induced salt tolerance in tomato. Scientific Reports, 2016, 6: 35392.
22. Zhu Tong^#, Deng Xing-Guang^#, Tan Wen-Rong, Zhou Xue, Luo Shi-Shuai, Han Xue-Ying, Zhang Da-Wei*, Lin Hong-Hui*. Nitric oxide is involved in brassinosteroid induced alternative respiratory pathway in Nicotiana benthamiana seedlings’ response to salt stress. Physiologia Plantarum, 2016, 156(2): 150-163.
23. Zou Li-Juan^#, Deng Xing-Guang^#, Han Xue-Ying, Tan Wen-Rong, Zhu Li-Jun, Xi De-Hui, Zhang Da-Wei ^#,*, Lin Hong-Hui*. Role of Transcription Factor HAT1 in Modulating Arabidopsis thaliana Response to Cucumber Mosaic Virus. Plant and Cell Physiology. 2016, 57(9): 1879-1889.
24. Jian We^#, Zhang Da-Wei ^#, Zhu Feng, Wang Shuo-Xun, Pu Xiao-Jun, Deng Xing-Guang, Luo Shi-Shuai, Lin Hong-Hui*. Alternative oxidase pathway is involved in the exogenous SNP-elevated tolerance of Medicago truncatula to salt stress. Journal of Plant Physiology, 2016, 193: 79–87.
25. Zhu Li-Jun, Deng Xing-Guang, Zou Li-Juan, Wu Jun-Qiang, Zhang Da-Wei*, Lin Hong-Hui. Proanthocyanidins accelerate the germination of cucumber (Cucumis sativus L.) seeds. Journal of Plant Biology. 2016, 59: 143-151.
26. Han Xue-Ying^#, Li Peng-Xu^#, Zou Li-Juan, Tan Wen-Rong, Zheng Ting, Zhang Da-Wei*, Lin Hong-Hui*. GOLDEN2-LIKE transcription factors coordinate the tolerance to Cucumber mosaic virus in Arabidopsis. Biochemical and Biophysical Research Communications. 2016. 477(4): 626-632.
27. Zhu Lijun^#, Deng Xingguang^#, Zou Lijuan, Zhang Dawei*, Lin Honghui*. Enhancement of stress tolerance in cucumber seedlings by proanthocyanidins. Biologia Plantarum. 2016, 61:323-332.
28. Wei Li-Jie^#, Deng Xing-Guang^#, Zhu Tong, Zheng Ting, Li Peng-Xu, Wu Jun-Qiang, Zhang Da-Wei*, Lin Hong-Hui*. Ethylene is involved in brassinosteroids induced alternative respiratory pathway in cucumber (Cucumis sativus L.) seedlings response to abiotic stress. Frontiers in Plant Science, 2015, 6:982.
29. Deng Xing-Guang^#, Zhu Tong^#, Zhang Da-Wei*, Lin Hong-Hui*. 2015. Alternative respiratory pathway is involved in brassinosteroid-induced environmental stress tolerance in Nicotiana benthamiana. Journal of Experimental Botany, 2015, 66(20): 6219-6232.
30. Zhang Da-Wei^#, Deng Xing-Guang^#, Fu Fu-Qiong, Lin Hong-Hui*. 2015. Induction of plant virus defense response by brassinosteroid and BR signaling in Arabidopsis thaliana. Planta, 241(4):875–885.
31. Fu Fa-Qiong ^#, Zhang Da-Wei^#, Deng Xing-Guang, Lin Hong-Hui*. 2015. Role of plastid signals in modulating Arabidopsis responses to Cucumber mosaic virus. Plant Growth Regulation, 75(3): 761-769.
32. Zhu Tong^#, Tan Wen-rong^#, Deng Xing-guang, Zheng Ting, Zhang Da-wei* and Lin Hong-hui*. 2015. Effects of brassinosteroids on quality attributes and ethylene synthesis in postharvest tomato fruit. Postharvest biology and technology, 100(1): 196-204.
33. Jian Wei^#, Zhang Da-Wei^#, Zhu Feng, Wang Shuo-Xun, Zhu Tong, Pu Xiao-Jun, Zheng-Ting, Feng Hong, Lin Hong-Hui*. 2015. Nitrate reductase-dependent nitric oxide production is required for regulation alternative oxidase pathway involved in the resistance to Cucumber mosaic virus infection in Arabidopsis. Plant Growth Regulation, 77: 99-107.
34. Zhang Da-Wei, Ye Hua-Xun, Guo Hong-qing, Johnson Abbagail, Lin Hong-Hui*, Yin Yan-hai*. 2014. Transrciption factors involved in brassinosteroid repressed gene expression and their regulation by BIN2 kinase. Plant Signal and behavior, e27849.
35. Zhang Da-Wei, Ye Hua-Xun, Guo Hong-Qing, Johnson Abbagail, Lin Hong-Hui*, Yin Yan-Hai. 2014. Transrciption Factor HAT1 is phosphorylated by BIN2 kinase and mediates Brassinsteroid repressed gene expression in Arabisopsis. Plant Journal, 77(1): 59-70.