周燕职 务:公共实验技术中心主任职 称:研究员学 历:博士研究生电 话:**传 真:通讯地址:成都市人民南路四段9号
邮政编码:610041电子邮件:zhouyan@cib.ac.cn
个人简历周燕,2004年毕业于中国科学院成都有机化学研究所,获理学博士学位,2004-2005年在香港中文大学从事博士后研究工作,2007-2010年在香港赛马会中药研究院工作,入选2010年中国科学院引进杰出技术人才(技术百人)。现任中国科学院成都生物研究所公共实验技术中心主任,研究员,博士生导师。主要从事多维色谱波谱联用技术平台的建立及其在天然产物、环境科学、化学生态学领域的应用研究;综合运用色谱、质谱、核磁共振等现代技术手段开展药用植物活性成分的结构鉴定,及其在在中(藏)药质量控制方面的应用研究,现已发表SCI论文80余篇。
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社会任职:
中国有机分析专业委员会委员,四川省质谱学会秘书长兼副理事长。
研究方向1)? 药物分析2)? 质谱分析
3)? 药物化学
代表论著?1.??????? D.H. He, L.S. Ding, H.X. Xu*, X.X. Lei, H.P. Xiao, and Y. Zhou*. DOI: Gymnothelignans A-O: conformation and absolute configuration analyses of lignans bearing tetrahydrofuran from Gymnotheca chinensis, the Journal of Organic Chemistry, 26, 2502-2508 (2012).
2.??????? X.J. Zhang, F.F.K. Choi, Y. Zhou, F.P. Leung, S. Tan, S.H Lin, H.X. Xu, W. Jia, J.J.Y. Sung, Z.W. Cai, Z.X. Bian*, Metabolite profiling of plasma and urine from rats with TNBS-induced acute colitis using UPLC-ESI-QTOF-MS-based metabonomics: A pilot study, FEBS Journal, 279, 2322–2338(2012).
3.??????? D.H. He, ?X.M. Xu, Y. Zhou*, W.L. Deng, B. Xia, L.S. Ding*, Terpenoids from Loxocalyx urticifolius, Helvetica Chimica Acta, 95(7), 1136-1143 (2012)
4.??????? B. Xia, Y. Zhou*, X. Liu, Y.C. Gu, J. Xiao, Q. Liu, L. S. Ding*, Direct Distinguish of Monosaccharides Using ESI Ion-Trap Tandem Mass Spectrometry and Principal Component Analysis, Rapid Communication in Mass Spectrometry, 26, 1259-1265 (2012).5.??????? Y. Zhou, S.X. Huang, J.X. Pu, J.R. Li, D.F. Chen, L.S. Ding, H.D. Sun, H.X. Xu*, Ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometric procedure for qualitative and quantitative analysis of nortriterpenoids and lignans in the genus Schisandra, Journal of Pharmaceutical and Biomedical Analysis, 56, 916-927 (2011)
6.??????? K.J. Xu, S.Y. Jiang, Y. Zhou*, Y.X. Zhang, B. Xia, X.M. Xu, Y. Zhou, M.K. Wang, L.S. Ding*, Discrimination of the Seeds of Notopterygium incisum and Notopterygium franchetii by Validated HPLC–DAD–ESI–MS Method and Principal Component Analysis, Journal of Pharmaceutical and Biomedical Analysis, 56,1089-1093 (2011)
7.??????? B. Xia, Z.F Tai, Y.C.Gu, B.J. Li, L.S. Ding, Y. Zhou*, MyMolDB: a micro-molecular database solution with open source and free components, Journal of Computational Chemistry, 32, 2942-2948 (2011) 8.??????? Y. Zhou, M.F. He, Franky F.K. Choi, Z.H. He, J.Z. Song , C.F. Qiao, S.L.Li, H.X. Xu*, A high sensitivity UPLC-MS/MS method for simultaneous determination and confirmation of triptolide in zebrafish embryos, Biomedical Chromatography, 25, 851-857 (2011)
9.??????? Y. Zhou, N. Li, Franky F.K. Choi, C.F. Qiao, J.Z. Song, S.L. Li, X. Liu, Z.W. Cai, Peter P. Fu, G. Lin*, H.X. Xu*, A new approach for simultaneous screening and quantification of toxic pyrrolizidine alkaloids in some potential PAs-containing plants by using ultra performance liquid chromatography-tandem quadrupole mass spectrometry, Analytica?Chimica?Acta, 681, 33-40 (2010)
10.???? Y. Zhou, S. Lee, Franky F.K. Choi, G. Xu, X. Liu, J.Z. Song, S.Li. Li, C.F. Qiao, H.X. Xu*, Qualitative and quantitative analysis of polycyclic polyprenylated acylphloroglucinols from Garcinia species using ultra performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flighttandem mass spectrometry, Analytica?Chimica?Acta, 678, 96-107 (2010)
11.???? Y. Zhou, Franky F.K. Choi, Z.Z. He, J.Z. Song, C.F. Qiao, X. Liu, L.S. Ding, S.L. Gesang, H.X. Xu*, Optimisation of UPLC conditions using response surface methodology for rapid separation and quantitative determination of phenolic compounds in Artemisia minor, Journal of Separation Sciences, 33(23-24), 3675-82 (2010).
12.???? Y. Zhou, S. X. Huang, J. Z. Song, C. F. Qiao, Q. B. Han, S. L. Li, H. X. Xu*. Screening and Identification of Polycyclic Polyprenylated Acylphloroglucinols from Garcinia Species Using Precursor Ion Discovery (PID) Scan and Ultra Performance Liquid Chromatography Q-TOF Electrospray Ionization Tandem Mass Spectrometry, Journal of American Society for Mass Spectrometry 10, 1844-1850 (2009).
13.???? Y. Zhou, J. Z. Song, Franky F. K. Choi, H. F. Wu, C. F. Qiao, L. S.? Ding, S. L. Gesang, H. X. Xu, Using SAS statistic strategy to obtain optimal gradient LC and ESI-QTOF-MS conditions to determine the alkaloids from Meconopsis species, Journal of Chromatography A, 1216 (42), 7013-7023 (2009).
14.???? Y. Zhou, G. Xu, F. F. Choi, L. S. Ding, Q. B. Han, J. Z. Song, C. F. Qiao, Q. S. Zhao, H. X. Xu, Qualitative and quantitative analysis of diterpenoids in Salvia species by liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry, Journal of Chromatography A, 1216 (24), 4847-4858 (2009).
15.???? Y. Zhou, B.L. Yang, J. Yang, S.X. Huang, H. D.Sun, H.X. Xu, L.S. Ding, Electrospray ionization tandem mass spectrometric analysis of ent-6,7-seco-kaurane diterpenoids from the Isodon species, Rapid Communications in Mass Spectrometry, 23, 138-146 (2009).
16.???? Y. Zhou, Q.B. Han, J.Z. Song, H.X. Xu*, Characterization of polyprenylated xanthones in Garcinia xipshuanbannaensis using liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry, Journal of Chromatography A, 1206 (2), 131-139 (2008).
17.???? Y. Zhou, X. Liu, J. Yang, Q.B. Han, J.Z. Song, S.L. Li, L.S. Ding, H. X. Xu*, Analysis?of?caged?xanthones?from?the?resin?of?Garcinia?hanburyi?using?ultra-performance?liquid?chromatography/electrospray?ionization?quadrupole?time-of-flight?tandem?mass?spectrometry, Analytica?Chimica?Acta, 629, 104-118 (2008).
18.????? Y. Zhou, S.X. Huang, L.M. Li, J. Yang, X. Liu, S.L. Peng, L.S. Ding, H.D. Sun. Negative electrospray ionization tandem mass spectrometric investigation of ent-kaurane diterpenoids from the genus Isodon. Journal of Mass Spectrometry, 43(1), 63-73 (2008).
承担科研项目情况
获奖及荣誉
3)? 药物化学