马超美教授简介作者：|发布日期：2013-09-30

马超美，女，内蒙古大学生命科学院生物系教授

Email:cmma@imu.edu.cn



本室招收博士后，工资按在岗讲师待遇发放。

液-质联用UPLC-QQQMS(Agilent1290-6430)可对外测试全扫描质谱、未知样品LC-MS/MS定性分析、已知样品LC-MRM定量分析等。

非常感谢科研经费资助者！
国家自然科学基金，内蒙古自然科学基金，内蒙古科技厅基金，内蒙古大学科研启动基金。中国博士后科学基金，国家大学生创新基金。

研究领域:

天然药物与功能食品研究


教育:

1998.4-2001.3日本富山医科药科大学（现与富山大学合并）药学博士
1996.4-1998.3日本富山医科药科大学（现与富山大学合并）药学硕士
1979.9-1983.7北京医学院药学系（现北京大学药学院）学士

工作经历:



2010.5-内蒙古大学生命科学院生物系教授
2006.7-2010.3日本富山大学和汉医药学综合研究所副教授
2003.3-2006.7加拿大纽芬兰记念大学药学院博士后
2001.5-2003.3北京大学药学院讲师-副教授
1994.4-1996.3日本富山医科药科大学和汉药研究所世川研修生-客员研究员
1983.8-1994.3内蒙古医学院药学系助教-讲师


部分论文：
1.Zhang,H.W.;Yerigui,Yang,Y.M.;Ma,C.M.StructuresandAntioxidantandIntestinalDisaccharidaseInhibitoryActivitiesofA-TypeProanthocyanidinsfromPeanutSkin.JAgricFoodChem61:8814?8820(2013).
2.Zhang,L.;Li,M.Y.;Wang,L.W.;Gao,J.;Ma,C.M.Isolation,Identification,QuantificationandInhibitoryActivityonHCVProteaseofCoumarinsfromViolayedoensis.CanChemTrans1:157-164(2013).
3.Hattori,M.;Ma,C.M.,Wei,Y.;ElDine,R.S.;Sato,N.SurveyofAnti-HIVandAnti-HCVCompoundsfromNaturalSources.CanChemTrans1:116-140(2013).
4.麻剑南,何倩倩,王雅丽,马超美.苹果皮有效成分及药理作用研究进展.食品与药品15:219-222(2013).
5.Meng,H.C.;Wang,S.;Li,Y.;Kuang,Y.Y.;Ma,C.M.ChemicalconstituentsandpharmacologicactionsofCynomoriumplants.ChinJNatMed11:0321?0329(2013).
6.Meng,H.C.;Ma,C.M.Flavan-3-ol-cysteineandacetylcysteineconjugatesfromediblereagentsandthestemsofCynomoriumsongaricumaspotentantioxidants.FoodChem141:2691-2696(2013).
7.Wang,W.;He,X.L.;Ma,C.M.Metabolismschemesofchlorogenic,quinicandcaffeicacidderivativesinratsdeducedbymolecularfragmentsdetectedwithoptimizedUPLC–APCI-MS/MS.IntJMassSpectrom337:34–42(2013).
8.Gao,J.;Sato,N.;Hattori,M.;Ma,C.M.ThesimultaneousquantificationofGanodermaacidsandalcoholsusingultraperformanceliquidchromatography-massspectrometrywithdynamicselectedreactionmonitoringmode.JPharmBiomedAnal74:246-249(2013).
9.Wu,Z.G.;Xu,H.Y.;Ma,Q.;Cao,Y.;Ma,J.N.;Ma,C.M.Isolation,identificationandquantificationofunsaturatedfattyacids,amides,phenoliccompoundsandglycoalkaloidsfrompotatopeel.FoodChem135:2425–2429(2012).ISSN:0308-8146
10.Ma,J.N.;Wang,S.L.;Zhang,K.;Wu,Z.G.;Hattori,M;Chen,G.L.;Ma,C.M.Chemicalcomponentsandantioxidantactivityofthepeelsofcommercialapple-shapedpear(fruitofPyruspyrifoliacv.pingguoli),JFoodSci77:1097–1102(2012).OnlineISSN:1750-3841.
11.Jin,J.S.,Tobo,T.,Chung,M.H.,Ma,C.M.;Hattori,M.Transformationoftrachelogenin,anaglyconeoftrachelosidefromsafflowerseeds,tophytoestrogenic(?)-enterolactonebyhumanintestinalbacteria.FoodChem134:74-80(2012).
12.Kitalong,C.;El-Halawany,A.M.;El-Dine,R.S.;Ma,C.M.;Hattori,M.PhenolicsfromPhalerianisidaiwithestrogenicactivity.RecNatProd6:296-300.(2012).
13.Zhong,Y.;Ma,C.M.;Shahidi,F.Antioxidantandantiviralactivitiesoflipophilicepigallocatechingallate(EGCG)derivatives.JFunctFood4:87-93.(2012).
14.Wang,Z.G.;Wang,X.J.;Sun,H.;Chen,L.;Ma,C.M.Determinationofnovelnitrogen-containingmetaboliteafteroraladministrationofswertiamarintorats.JAsianNatProdRes.14(2):176-181(2012).
15.危英,马超美,梁光义,魏升华,危莉,服部征雄.民族药野梦花基源及提取物抗丙型肝炎病毒NS3/4A蛋白酶活性研究.时珍国医国药23:1661-1663(2012).
16.Nakamura,K.;Nishihata,T.;Jin,J-S.;Ma,C.M.;Komatsu,K.;Iwashima,M.;Hattori,M.TheC-glucosylbondofpuerarinwascleavedhydrolyticallybyahumanintestinalbacteriumstrainPUEtoyielditsaglyconedaidzeinandanintactglucose.ChemPharmbull59:23-27(2011).
17.Ma,C.M;Abe,T.;Komiyama,T.;Wang,W.;Hattori,M.;Daneshtalab,M.Synthesis,anti-fungaland1,3-?-D-glucansynthaseinhibitoryactivitiesofcaffeicandquinicacidderivatives.BioorgMedChem18:7009-7014(2010).
18.Ma,C.M.;Kawahata,T.;Hattori,M.;Otake,T.;Wang,L.;Daneshtalab,M.Synthesis,anti-HIVandanti-oxidantactivitiesofcaffeoyl5,6-anhydroquinicacidderivatives.BioorgMedChem18:863-869(2010).
19.Ma,C.M.;Sato,N.;Li,X.Y.;Nakamura,N.;Hattori,M.Flavan-3-olcontents,anti-oxidativeanda-glucosidaseinhibitoryactivitiesofCynomoriumsongaricum.FoodChem118:116-119(2010).
20.Ma,C.M.;Wu,X.H.;Hattori,M.;Wang,X.J.;Kano,Yoshihiro.HCVproteaseinhibitory,cytotoxicandapoptosis-inducingeffectsofoleanolicacidderivatives.JPPS.12:243-248(2009).
21.Ma,C.M.;Wei,Y.;Wang,Z.G.;Hattori,M.TriterpenesfromCynomoriumsongaricum—analysisofHCVproteaseinhibitoryactivity,quantification,andcontentchangeundertheinfluenceofheating.JNatMed63:9-14(2009).
22.Ma,C.M.;Hattori,M.;Daneshtalab,M.;Wang,L.ChlorogenicAcidDerivativeswithAlkylChainsofDifferentLengthsandOrientations:Potenta-GlucosidaseInhibitors.JMedChem51:6188-6194(2008).
23.Ma,C.M.;Hattori,M.;Chen,H.B.;Cai,S.-Q.;Daneshtalab,M.ProfilingthePhenolicCompoundsofArtemisiapectinatabyHPLC-PAD-MSⁿ.PhytochemAnalysis19:294-300(2008).
24.Ma,C.M.;Kully,M.;Khan,J.K.;Hattori,M.;Daneshtalab,M.Synthesisofchlorogenicacidderivativeswithpromisingantifungalactivity.BioorgMedChem.15:6830-6833(2007).
25.Ma,C.M.;Winsor,L.;Daneshtalab,M.QuantificationofspiroetherisomersandherniarinofdifferentpartsofMatricariamatricarioidesandflowersofChamaemelumnobile.PhytochemAnalysis.18:42-49(2007).
26.Ma,C.M.;Takeda,S.;Hibino,S.;Daneshtalab,M.Synthesisofpeptidomimeticanaloguesofechinocandins.Heterocycles,68:721-732,(2006).
27.Ma,C.M.;Cai,S.Q.;Cui,J.R.;Wang,R.Q.;Tu,P.F.;Hattori,M.;Daneshtalab,M.Thecytotoxicactivityofursolicacidderivatives.EurJMedChem40:582-589(2005).
28.Ma,C.M.;Nakamura,N.;Nowawi,A.;Hattori,M.;Cai,S.Q.ANovelProtoilludaneSesquiterpenefromtheWoodofXanthocerassorbifolia.ChinChemLett15:65-67(2004).
29.马超美,中村宪夫,服部征雄,蔡少青.锁阳的抗艾滋病毒蛋白酶活性成分（2）-齐墩果酸丙二酸半酯的分离和鉴定.中国药学杂志37:336-338(2002).
30.Ma,C.M.;Nakamura,N.;Hattori,M.;Kawahata,T.;Otake,T.Inhibitoryeffectsoftriterpene-azidothymidineconjugatesonproliferationofhumanimmunodeficiencyvirustype1anditsprotease.ChemPharmBull50:877-880(2002).
31.Ma,C.M.;Nakamura,N.;Miyashiro,H..;Hattori,M.;Komatsu,K.;Kawahata,T.;Otake,T.ScreeningofChineseandMongolianherbaldrugsforanti-humanimmunodeficiencyvirustype1(HIV-1)activity.PhytotherRes16:186-189(2002).
32.Ma,C.M.;Nakamura,N.;Min,B.S.;Hattori,M.TriterpenesandlignansfromArtemisiacaruifoliaandtheircytotoxiceffectsonMeth-AandLLCtumorcelllines.ChemPharmBull49:183-187(2001).
33.Ma,C.M.;Nakamura,N.;Mattori,M.InhibitoryeffectsonHIV-1proteaseoftri-p-coumaroylspermidinefromArtemisiacaruifoliaandrelatedamides.ChemPharmBull49:915-917(2001).
34.Ma,C.M.;Nakamura,N.;Hattori,M.;Kakuda,H.;Qiao,J.C.;Yu,H.L.;InhibitoryeffectsonHIV-1proteaseofconstituentsfromthewoodofXanthocerassorbifolia.JNatProd63:238-242(2000).
35.Ma,C.M.;Nakamura,N.;Hattori,M.;Z.S.;Komatsu,K.GuaianedimersandgermacranolidefromArtemisiacaruifolia.JNatProd63:1626-1629(2000).
36.Ma,C.M.;NakamuraN.;Hattori,M.ChemicalmodificationofoleanenetypetriterpenesandtheirinhibitoryactivityagainstHIV-1proteasedimerization.ChemPharmBull48:1681-1688(2000).
37.Ma,C.M.;Nakamura,N.;Miyashiro,H.;HattoriM.;Shimotohno,K.InhibitoryeffectsofconstituentsfromCynomoriumsongaricumandrelatedtriterpenederivativesonHIV-1protease.ChemPharmBull47:141-145(1999).
38.Ma,C.M.;Nakamura,N.;Hattori,M.SaponinsandC-glycosylflavonesfromtheseedsofAbrusprecatorius.ChemPharmlBull46:982-987(1998).
39.Ma,C.M.;MiyashiroH,HattoriM,ShimotohnoK.ScreeningofChineseandMongoliantraditionalmedicinesfortheinhibitoryactivityonhumanimmunodeficiencyvirustype1protease.JTradMed12:418-419(1995).
40.马超美,贾世山,孙韬,张义文.锁阳中三萜及甾体成分的研究.药学学报28:152-5(1993)
41.Wang,W.;Ma,C.M.;Hattori,M.MetabolismandPharmacokineticsofRhynchophyllineinRats.BioPharmBull33:669-676(2010).
42.Wang,W.;Ma,C.M.;Hattori,M.MetabolismofisorhynchophyllineinratsdetectedbyLC-MS.JPPS13:27-37(2010).
43.Wang,W.;Ma,C.M.;Hattori,M.Simultaneousdeterminationofrhynchophylline,isorhynchophylline,andtheireightmetabolitesinrats.JTradMed27:15-29(2010).
44.Wei,Y.;Ma,C.M.;Hattori,M.SynthesisandevaluationofA-secotypetriterpenoidsforanti-HIV-1proteaseactivity.EurJMedChem44:4112-4120(2009).
45.Sato,N.;Ma,C.M.;Komatsu,K.;Hattori,M.Triterpene-farnesylhydroquinoneconjugatesfromGanodermasinense.JNatProd72:958-961(2009).
46.Wei,Y.;Ma,C.M.;Hattori,M.Synthesisofdammarane-typetriterpenederivativesandtheirabilitytoinhibitHIVandHCVproteases.BioorgMedChem17:3003-3010(2009).
47.Wei,Y.;Ma,C.M.;Hattori,M.Anti-HIVproteasetriterpenoidsfromtheacidhydrolysateofPanaxginseng.PhytochemistryLetters2:63-66(2009).
48.Phuong,D.T.;Ma,C.M.;Hattori,M.;Jin,J.S.InhibitoryEffectsofAntrodinsA-EfromAntrodiacinnamomeaandTheirMetabolitesonHepatitisCVirusProtease.PhytotherRes23:582-584(2009).
49.Yu,J,;Ma,C.M.;Long,C.F.;Wang,X.;Shang,M.Y.;Cai,S.Q.;Hattori,M.;Namba,T.AnewaristololactamfromAsarummaximum.JournalofChinesePharmaceuticalSciences18:183–185(2009).
50.Xu,Q.;Ma,C.M.;Wang,W.;Fu,X.;TangC.Y.;Hattori,M.Studyonthenitricoxidegeneratingeffectsfromaristolochicacidinvitro.EurJMassSpectrom14:231-238(2008).
51.WeiY;Ma,C.M.;ChenD.Y;HattoriM.Anti-HIV-1proteasetriterpenoidsfromStauntoniaobovatifoliolaHayatasubsp.intermedia.Phytochemistry69:1875-1879(2008).
52.Wang,Z.G.;MaC.M.;Tang,S.H.;Xiao,H,;Kakiuchi,N.;Kida,H.;Hattori,M.QualitativeandQuantitativeAnalysisofSwertiaHerbsbyHighPerformanceLiquidChromatography-DiodeArrayDetector-MassSpectrometry(HPLC-DAD-MS).ChemPharmBull56:485-490(2008).
53.Lee,J.S.;Ma,C.M.;Hattori,M.Quantificationofergosterolandergosterolperoxideinseveralmedicinalfungibyhighperformanceliquidchromatographymonitoredwithadiodearraydetection-atmosphericpressurechemicalionization-iontrapmassspectrometer.JTradMed25:18-23(2008).
54.Lee,J.S.;Ma,C.M.;Park,D.K.;Yoshimi,Y.;Hatanaka,M.;Hattori,M.Transformationofergosterolperoxidetocytotoxicsubstancesbyratintestinalbacteria.BioPharmBull31:949-54(2008).
55.Loomis,T.G.;Ma,C.M.;Daneshtalab,M.MedicinalplantsandherbsofNewfoundland.Part1.ChemicalconstituentsoftheaerialpartofPineappleweed(Matricariamatricarioides).Daru12:131-135(2004).
56.Nawawi,A.;Ma,C.M.;Nakamura,N.;Hattori,M.;Kurokawa,M.;Shiraki,K.;KashiwabaN.;Ono,M.Anti-herpessimplexvirusactivityofalkaloidsisolatedfromStephaniacepharantha.BioPharmBull22:268-274(1999).
57.Kawata,Y.;Ma,C.M.;Meselhy,M.R.;Nakamura,N.;Wang,H.;Hattori,M.;Namba,T.;Satoh,K.;Kuraishi,Y.Conversionofaconitinetolipoaconitinebyhumanintestinalbacteriaandtheirantinociceptiveeffectsinmice.JTradMed16:15-23(1999).
58.Lim,Y.A.;Ma,C.M.;Kusumoto,I.T.;Miyashiro,H.;Hattori,M.;Gupta,M.P.;Correa,M.HIV-1reversetranscriptaseinhibitoryprinciplesfromChamaesycehyssopifolia.PhytotherRes11:22-27(1997).
59.Jia,S.S.;Ma,C.M.;Li,Y.H.;Hao,J.H.GlycosidesofphenolicacidandflavonoidsfromtheleavesofGlycyrrhizauralensisFisch.药学学报27:441-4(1992).(CT5)
60.Jia,S.S.;Ma,C.M.;Jan-MinWang,studyontheflavonoidconstituentsfromtheaerialpartofGlycyrrhizauralesis.药学学报25:758-762(1990).(CT4)
61.Jia,S.S.;Ma,C.M.;Zhao,L.F.AliphaticconstituentsfromthepollenofTyphaangustifoliaL.植物学报32:465-8(1990).
62.Dong,S.W.;Wang,X.;Shang,M.Y.;Ma,C.M.;Zhang,S.X.;Li,X.W.;Xu,M.J.;Cai,S.Q.;Namba,T.SesquiterpeneandAristolochicAcidDerivativesfromThotteahainanensis,HelveticaChimicaActa:354-360(2010).
63.Wang,J.;ChungM.H.;XueB.;MaH.;Ma,C.M.;Hattori,M.EstrogenicandAntiestrogenicActivitiesofPhloridzin.BioPharmBull33,592-597(2010).
64.ElDine,R.S.;ElHalawany,A.M.;Ma,C.M.;Hattori,M.InhibitionofthedimerizationandactivesiteofHIV-1proteasebysecondarymetabolitesfromtheVietnamesemushroomGanodermacolossum.JNatProd.72:2019-23(2009).
65.Sato,N.;Zhang,Q.;Ma,C.M.;Hattori,M.Anti-HIV-1proteaseactivityofnewlanostain-typetriterpenoidsfromGanodermasinense.ChemPharmBull57:1076-1080(2009).
66.Zhang,Q.;Zuo,F.;Nakamura,N.;Ma,C.M.;Hattori,M.MetabolismandpharmacokineticsinratsofganoderiolF,ahighlycytotoxicandantitumortriterpenefromGanodermalucidum.JNatMed63:304-310(2009).
67.Tang,S.H.;Wang,Z.G.;MaC.M.;Hattori,M.SimultaneousdeterminationoftenbioactiveconstituentsinEucommiaulmoidesleavesandTochuteaproductsbyhigh-performanceliquidchromatography-diodearraydetector-massspectrometry(HPLC-DAD-MS).JTradMed25:112-118(2008).
68.ElDine,R.S.;ElHalawany,A.M.;Ma,C.M.;Hattori,M.Anti-HIV-1ProteaseActivityofLanostaneTriterpenesfromtheVietnameseMushroomGanodermacolossum.J.Nat.Prod.71:1022-1026(2008).
69.Wang,Z.G.;Tang,S.H.;MaC.M.;Toyooka,N.;Kida,H.;Kawasaki,M.;Hattori,M.Determinationofnovelnitrogen-containingmetabolitesafteroraladministrationofswertiamarintorats.JTradMed25:29-34(2008).
70.ElDine,R.S.;ElHalawany,A.M.;Nakamura,N.;Ma,C.M.;Hattori,M.NewlanostanetriterpenelactonesfromtheVietnamesemushroomGanodermacolossum(FR.)C.F.BAKER.ChemPharmBull56:642-646(2008).
71.El-Halawany,A.M.;Chung,M.H.;Ma,C.M.;Komatsu,K.;Nishihara,T.;Hattori,M.Anti-estrogenicactivityofmansorinsandmansononesfromtheheartwoodofMansoniagageiDRUMM.ChemPharmBull55:1332-1337(2007).
72.El-Halawany,A.M.;Chung,M.H.;Nakamura,N.;Ma,C.M.;Nishihara,T.;Hattori,M.Estrogenicandanti-estrogenicactivitiesofCassiatoraphenolicconstituents.Chem.Pharm.Bull.Vol.55:1476-1482(2007).

天然药物与功能食品研究室主要成员:


博士后：


王伟博士

(复旦大学硕士，日本富山大学博士，昆明医科大学药学院副教授副院长，内蒙古大学在职博士后，中国博士后面上基金及特别资助获得者)


OlusegunAjala博士


(尼日利亚拉格斯大学博士，讲师，内蒙古大学博士后，中国博士后“中非伙伴计划”资助获得者)




博士生：

张慧文，布拉干图雅，王玲娜，宝乐日，阿吉吉雅，高杰


硕士生：

何小丽，冀敏，其其格，麻剑南，王雅丽，张轲，许海燕，马琼，张玉，叶日贵，武志刚（与本院王迎春教授研究室合作培养生）



科学研究照片：


　
　
　
　
　
　
　
　
　
　
　
　
　
　
　
　
　
　
　











































　
　
　
　
　
　
　
　
　
　
　




























室外活动照片：


　
　
　

　
　










　
　












(日本学者服部征雄教授来访时和研究室成员参观内蒙古大唐药业)