基本信息Personal Information
副教授硕士生导师
主要任职：无
性别：男
毕业院校：浙江大学
学位：博士
在职信息：在职
所在单位：盘锦校区生命与医药学院
电子邮箱：
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个人简介Personal Profile
科研项目：1. 辽宁省自然科学基金面上项目，**，多重靶向转座子CRISPR/Cas9基因载体的构建与应用，2017/05-2019/04
2. 教育部留学归国人员科研启动基金项目，第49批，原生细胞模型protocell作为基因载体的研究，2015/03-2017/03
3. 国家自然科学基金面上项目，**，基于介孔二氧化硅的门控靶向给药系统的构建与性能评价，2010/01-2012/12
4. 浙江省自然科学基金面上项目，Y**，新型双分子靶向基因传递系统的研究，2010/01-2011/12
5. 国家自然科学基金面上项目，**，“连环”靶向基因载体的研究与应用，2009/01-2009/12
已发表的论文：
1. Li Wang, Dongli Yu?, Rui Dai?, Duo Fu, Wenzhe Li?, Zhaoming Guo?, Changhao Cui?, Jianqiang Xu, Song Shen, Kun Ma*. PEGylated doxorubicin cloaked nano-graphene oxide for dual-responsive photochemical therapy. Int J Pharm. 2019; 25(557): 66-73. (SCI, IF=4.213)
2. Kun Ma*, Duo Fu, Yajun Liu, Rui Dai, Dongli Yu, Zhaoming Guo, Changhao Cui, Li Wang, Jinaqiang Xu, Chuanbin Mao*. Cancer cell targeting, controlled drug release and intracellular fate of biomimetic membrane-encapsulated drug-loaded nano-graphene oxide nanohybrids. J Mater Chem B. 2018; 6(31): 5080-5090. (SCI, IF=5.047)
3. Kun Ma*, Duo Fu, Dongli Yu, Changhao Cui, Li Wang, Zhaoming Guo, Chuanbin Mao. Targeted delivery of in situ PCR-amplified Sleeping Beauty transposon genes to cancer cells with lipid-based nanoparticle-like protocells. Biomaterials. 2017;121:55-63. (IF: 10.273)
4. Kun Ma*, Dong-Dong Wang, Yiyang Lin, Jianglin Wang, Valery Petrenko, Chuanbin Mao. Synergetic targeted delivery of sleeping-beauty transposon system to mesenchymal stem cells using LPD nanoparticles modified with phage-displayed targeting peptide. Adv. Funct. Mater. 2013;6;23:1172-1181 (IF: 15.621)
5. Kun Ma*, Minxin Hu, Yan Qi, Liyan Qiu, Yi Jin, Jingmou Yu, Bo Li. Structure–transfection activity relationships with glucocorticoid–polyethylenimine conjugate nuclear gene delivery systems. Biomaterials 2009;30:3780–3789 (IF: 10.273)
6. Kun Ma*, Minxin Hu, Yan Qi, Jihong Zou, Liyan Qiu, Yi Jin, Xiaoying Ying, Hongying Sun. PAMAM–Triamcinolone acetonide conjugate as a nucleus–targeting gene carrier for enhanced transfer activity. Biomaterials 2009;30:6109–6118 (IF: 10.273)
7. Kun Ma*, Min-Xin Hu, Meng Xie, Hai-Jun Shen, Li-Yan Qiu, Wei-min Fan, Hong-Ying Sun, Shu-Qing Chen, Yi Jin. Investigation of Polyethylenimine–grafted– Triamcinolone acetonide as Nucleus–Targeting Gene Delivery Systems. J. Gene Med. 2010; 12: 669–680. (IF: 1.561)
8. Kun Ma*, Haijun Shen, Song Shen, Men Xie, Chuanbin Mao, Liyan Qiu, Yi Jin. Development of a successive targeting liposome with multi-ligand for efficient targeting gene delivery. J. Gene Med. 2011; 13: 290–301. (IF: 1.561)
9. Zhaoming Guo*, Wenqing Li, Yue Yuan, Kun Zheng, Yu Tang, Kun Ma, Changhao Cui, Li Wang, Bing He, Qiang Zhang. Improvement of chemosensitivity and inhibition of migration via targeting tumor epithelial-to-mesenchymal transition cells by ADH-1-modified liposomes. Drug Delivery. 2018; 25(1): 112-121. (SCI, IF=3.829)
10. Zhaoming Guo*, Kun Zheng, Zhenquan Tan, Ye Liu, Ziyin Zhao, Guang Zhu, Kun Ma, Changhao Cui, Li Wang, Tianyu Kang. Overcoming drug resistance with functional mesoporous titanium dioxide nanoparticles combining targeting, drug delivery and photodynamic therapy. Journal of Materials Chemistry B. 2018; 6(46): 7750-7759. (SCI, IF=5.047)
11. Wenqing Li, Zhaoming Guo*, Kun Zheng, Kun Ma, Changhao Cui, Li Wang, Yue Yuan, Yu Tang. Dual targeting mesoporous silica nanoparticles for inhibiting tumour cell invasion and metastasis. Int. J. Pharm. 2017, 20; 534(1-2): 71-80. (SCI, IF=4.213)
12. Shen HJ, Shi H, Ma K*, Xie M, Tang LL, Shen S, Li B, Wang XS, Jin Y. Polyelectrolyte capsules packaging BSA gels for pH-controlled drug loading and release and their antitumor activity. Acta Biomater. 2013; 9: 6123-6133. (IF: 6.638)
13. Xie M, Shi H, Ma K*, Shen H, Li B, Shen S, Wang X, Jin Y. Hybrid nanoparticles for drug delivery and bioimaging: mesoporous silica nanoparticles functionalized with carboxyl groups and a near-infrared fluorescent dye. J. Colloid. Interface Sci. 2013; 395:306-314. (IF: 6.361)
14. Xie M, Shi H, Li Z, Shen H, Ma K*, Li B, Shen S, Jin Y. A multifunctional mesoporous silica nanocomposite for targeted delivery, controlled release of doxorubicin and bioimaging. Colloids Surf B Biointerfaces. 2013;110C:138-147. (IF: 3.973)
15. Haijun Shen, Hui Shi, Men Xie, Kun Ma*, et al. Biodegradable chitosan/alginate BSA-gel-capsules for pH-controlled loading and release of doxorubicin and treatment of pulmonary melanoma. J Mater Chem B. 2013;1:32:3906-3917. (IF: 5.047)
教育经历Education Background
工作经历Work Experience
2011.92013.3
浙江大学
药剂学
博士
2002.92005.7
新疆医科大学
药剂学
硕士
1993.91997.7
新疆医科大学
药学
学士
1990.91993.7
新疆乌鲁木齐市第六中学
2014.9至今
大连理工大学
副教授
2011.32014.2
美国俄克拉玛大学化学系
博士后
1997.82002.8
新疆心脑血管病医院
药剂师
研究方向Research Focus
社会兼职Social Affiliations
药物/基因靶向给药系统；纳米给药系统，药物新剂型与新技术
基本信息Personal Information
副教授硕士生导师
主要任职：无
性别：男
毕业院校：浙江大学
学位：博士
在职信息：在职
所在单位：盘锦校区生命与医药学院
电子邮箱：
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论文成果 More>>
Liu, Yajun,Xu, Jianqiang,Ma, Kun,Dai, Rui,Wei, Quyu,Li, Wenzhe,Zhu, Guang,Chi, Hao,Guo, Zhaoming,Wang, Li,Cui, Changhao.Dual-Functionalized Janus Mesoporous Silica Nanoparticles with Active Targeting and Charge Reversal for Synergistic Tumor-Targeting Therapy[J],ACS APPLIED MATERIALS & INTERFACES,2019,11(47):44582-44592
Guo Zhaoming,Wang Li,Liu Ye,Zhou Hao,Zheng Kun,Wang Dong,Jia Mingli,Xu Pengcheng,Ma Kun,Cui Changhao.CD47-targeted bismuth selenide nanoparticles actualize improved photothermal therapy by increasing macrophage phagocytosis of cancer cells[J],Colloids and surfaces. B, Biointerfaces,2019,184:110546
Wang, Li,Ma, Kun,Yu, Dongli,Dai, Rui,Fu, Duo,Li, Wenzhe,Guo, Zhaoming,Cui, Changhao,Xu, Jianqiang,Shen, Song.PEGylated doxorubicin cloaked nano-graphene oxide for dual-responsive photochemical therapy[J],INTERNATIONAL JOURNAL OF PHARMACEUTICS,2019,557:66-73
Guo, Zhaoming,Kang, Tianyu,Zheng, Kun,Tan, Zhenquan,Liu, Ye,Zhao, Ziyin,Zhu, Guang,Ma, Kun,Cui, Changhao,Wang, Li.Overcoming drug resistance with functional mesoporous titanium dioxide nanoparticles combining targeting, drug delivery and photodynamic therapy[J],JOURNAL OF MATERIALS CHEMISTRY B,2018,6(46):7750-7759
Guo Zhaoming,Zhang Qiang,Li Wenqing,Yuan Yue,Zheng Kun,Tang Yu,Ma Kun,Cui Changhao,Wang Li,He Bing.Improvement of chemosensitivity and inhibition of migration via targeting tumor epithelial-to-mesenchymal transition cells by ADH-1-modified liposomes.[J],Drug delivery,2018,25(1):112-121
Ma, Kun,Mao, Chuanbin,Fu, Duo,Liu, Yajun,Dai, Rui,Yu, Dongli,Guo, Zhaoming,Cui, Changhao,Wang, Li,Xu, Jianqiang.Cancer cell targeting, controlled drug release and intracellular fate of biomimetic membrane-encapsulated drug-loaded nano-graphene oxide nanohybrids[J],JOURNAL OF MATERIALS CHEMISTRY B,2018,6(31):5080-5090
专利
暂无内容
著作成果
暂无内容
科研项目
多重靶向转座子CRISPR/Cas9基因载体的构建与应用, 省、市、自治区科技项目, 2017/04/18, 进行
原生细胞模型protocell作为基因载体的研究, 主管部门科技项目, 2015/03/02, 进行
基于知识库和深度学习的生物医学实体关系抽取研究, 国家自然科学基金项目, 2017/08/17, 进行
针对肿瘤EMT细胞设计的多价配体修饰给药系统的抗肿瘤转移研究, 国家自然科学基金项目, 2016/08/17, 进行
基本信息Personal Information
副教授硕士生导师
主要任职：无
性别：男
毕业院校：浙江大学
学位：博士
在职信息：在职
所在单位：盘锦校区生命与医药学院
电子邮箱：
扫描关注
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研究领域
当前位置: 中文主页 >> 科学研究 >> 研究领域基本信息Personal Information
副教授硕士生导师
主要任职：无
性别：男
毕业院校：浙江大学
学位：博士
在职信息：在职
所在单位：盘锦校区生命与医药学院
电子邮箱：
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个人学术主页
论文成果
当前位置: 中文主页 >> 科学研究 >> 论文成果[1]Liu, Yajun,Xu, Jianqiang,Ma, Kun,Dai, Rui,Wei, Quyu,Li, Wenzhe,Zhu, Guang,Chi, Hao,Guo, Zhaoming,Wang, Li,Cui, Changhao.Dual-Functionalized Janus Mesoporous Silica Nanoparticles with Active Targeting and Charge Reversal for Synergistic Tumor-Targeting Therapy[J],ACS APPLIED MATERIALS & INTERFACES,2019,11(47):44582-44592
[2]Guo Zhaoming,Wang Li,Liu Ye,Zhou Hao,Zheng Kun,Wang Dong,Jia Mingli,Xu Pengcheng,Ma Kun,Cui Changhao.CD47-targeted bismuth selenide nanoparticles actualize improved photothermal therapy by increasing macrophage phagocytosis of cancer cells[J],Colloids and surfaces. B, Biointerfaces,2019,184:110546
[3]Wang, Li,Ma, Kun,Yu, Dongli,Dai, Rui,Fu, Duo,Li, Wenzhe,Guo, Zhaoming,Cui, Changhao,Xu, Jianqiang,Shen, Song.PEGylated doxorubicin cloaked nano-graphene oxide for dual-responsive photochemical therapy[J],INTERNATIONAL JOURNAL OF PHARMACEUTICS,2019,557:66-73
[4]Guo, Zhaoming,Kang, Tianyu,Zheng, Kun,Tan, Zhenquan,Liu, Ye,Zhao, Ziyin,Zhu, Guang,Ma, Kun,Cui, Changhao,Wang, Li.Overcoming drug resistance with functional mesoporous titanium dioxide nanoparticles combining targeting, drug delivery and photodynamic therapy[J],JOURNAL OF MATERIALS CHEMISTRY B,2018,6(46):7750-7759
[5]Guo Zhaoming,Zhang Qiang,Li Wenqing,Yuan Yue,Zheng Kun,Tang Yu,Ma Kun,Cui Changhao,Wang Li,He Bing.Improvement of chemosensitivity and inhibition of migration via targeting tumor epithelial-to-mesenchymal transition cells by ADH-1-modified liposomes.[J],Drug delivery,2018,25(1):112-121
[6]Ma, Kun,Mao, Chuanbin,Fu, Duo,Liu, Yajun,Dai, Rui,Yu, Dongli,Guo, Zhaoming,Cui, Changhao,Wang, Li,Xu, Jianqiang.Cancer cell targeting, controlled drug release and intracellular fate of biomimetic membrane-encapsulated drug-loaded nano-graphene oxide nanohybrids[J],JOURNAL OF MATERIALS CHEMISTRY B,2018,6(31):5080-5090
[7]Zhou, Huiwei,Liu, Zhuang,Ning, Shixian,Yang, Yunlong,Lang, Chengkun,Lin, Yingyu,Ma, Kun.Leveraging prior knowledge for protein-protein interaction extraction with memory network[J],DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION,2018,2018
[8]Li, Wenqing,Guo, Zhaoming,Zheng, Kun,Ma, Kun,Cui, Changhao,Wang, Li,Yuan, Yue,Tang, Yu.Dual targeting mesoporous silica nanoparticles for inhibiting tumour cell invasion and metastasis[J],INTERNATIONAL JOURNAL OF PHARMACEUTICS,2017,534(1-2):71-80
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基本信息Personal Information
副教授硕士生导师
主要任职：无
性别：男
毕业院校：浙江大学
学位：博士
在职信息：在职
所在单位：盘锦校区生命与医药学院
电子邮箱：
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专利
当前位置: 中文主页 >> 科学研究 >> 专利共0条0/0
基本信息Personal Information
副教授硕士生导师
主要任职：无
性别：男
毕业院校：浙江大学
学位：博士
在职信息：在职
所在单位：盘锦校区生命与医药学院
电子邮箱：
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著作成果
当前位置: 中文主页 >> 科学研究 >> 著作成果共0条0/0
基本信息Personal Information
副教授硕士生导师
主要任职：无
性别：男
毕业院校：浙江大学
学位：博士
在职信息：在职
所在单位：盘锦校区生命与医药学院
电子邮箱：
扫描关注
个人学术主页
科研项目
当前位置: 中文主页 >> 科学研究 >> 科研项目多重靶向转座子CRISPR/Cas9基因载体的构建与应用, 辽宁省自然科学基金, 2017/04/18, 进行
原生细胞模型protocell作为基因载体的研究, 教育部留学归国人员科研启动基金项目, 2015/03/02, 进行
基于知识库和深度学习的生物医学实体关系抽取研究, 国家自然科学基金, 2017/08/17, 进行
针对肿瘤EMT细胞设计的多价配体修饰给药系统的抗肿瘤转移研究, 国家自然科学基金, 2016/08/17, 进行
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