导师基本信息
姓　　名
尚红
导师类别
博导

性别
女
招生年度
2020

出生年月
196010
专业职称
主任医师

院系
第一临床学院
政治面貌
中国农工民主党党员

科室
检验科
手机
*********

工作单位
第一临床学院
学术职称
教授

最后学位
医学博士学位
办公室电话
*********

最后学历
博士研究生
电子信箱
p3lab@yeah.net

个人简介　　　
尚红教授主要从事艾滋病防治研究和临床检验研究。主持“十三五"、“十二五”、“十一五”国家科技重大专项、“十五”国家科技攻关、“973”项目，在Nature、N Engl J Med等杂志发表SCI论文190余篇；主编专著十余部；获国家专利5项；以第一完成人获国家科技进步二等奖2项、省科技进步奖3项；培养研究生110余名。
研究方向简介　　
尚红教授主要研究方向为艾滋病流行病学与致病机制研究。通过建立实验研究和临床研究的开放共享平台，为硕士、博士研究生开展创新性研究提供良好条件。至今已培养博士研究32人，硕士研究生57人，多名毕业生在美国哈佛大学、国家CDC、中国医科大学等单位已成为
社会兼职　　　
国务院学位委员会学科评议组成员、中华医学会常务理事、中华医学会检验分会主任委员、中国性病艾滋病防治协会副会长，卫生部疾病预防控制专家委员会艾滋病与性病防治分委会副主任委员、中国医师协会检验医师分会副会长等职。同时担任《中华检验医学杂志》主编、Clinical Chemistry and Laboratory Medicine杂志编委等职
所获荣誉　　　
何梁何利基金科学与技术进步奖，法国医学科学院塞维雅奖，全国优秀科技工作者，全面建设小康社会先进个人，全国“巾帼建功”标兵，中国医师奖，辽宁省领军人才，入选辽宁省首批院士后备人选培养工程

在学研究生
硕士学术学位人数 博士学术学位人数
硕士专业学位人数 博士专业学位人数
同等学力硕士学术学位人数 同等学力博士学术学位人数
同等学力硕士专业学位人数 同等学力博士专业学位人数
研究生就业　　　(300字内)
研究生毕业后就职业国内外科研机构及各省市CDC和医院检验科、医大附属医院等。1名称为哈佛大学副教授，1名成为美国CDC中国办事处项目官员，6名成为教授/博士生导师，10余名成为副教授，他们已经承担国家自然科学基金、国家科技重大专项等重大课题。

教育经历
时间（起始年-截止年） 毕业院校 专业名称 所获学位
1978-1983 中国医科大学 临床医学 医学学士学位
1991-1996 日本山梨医科大学 生态学 医学博士学位
工作经历
时间（起始年-截止年） 工作单位 承担职务 从事工作
-至今 中国医科大学附属第一医院检验科 主任/主任医师 科学研究和管理
-至今 中国医科大学 副校长/教授 科学研究和管理
-至今 中国医科大学附属第一医院 院长/教授 科学研究和管理
承担课题(近5年)
时间（起始年月-截止年月） 批准部门 课题名称 课题经费(万)
201809-202108 辽宁省科技厅 男男同性恋人群艾滋病防治研究 50
201803-201903 中国医学科学院 中国医学科学院重点实验室建设经费 100
201801-201812 中国医学科学院 艾滋病分子检测与精准干预 100
201701-201912 中华人民共和国教育部 教育部创新团队：艾滋病致病机制及治疗研究 300
201701-202012 中华人民共和国科技部"十三五"国家科技重大专项 艾滋病生物标志物和疫情预警预测模型研究 6674.32
学术论文(近5年)
文章题目 杂志名称 发表年 卷期页 收录情况 影响因子
Rapid CD4+ T-cell decline is associated with coreceptor switch among MSM primarily infected with HIV-1 CRF01_AE in Northeast China AIDS 2019 33(1):0 SCI 4.999
Cofilin Hyperactivation in HIV Infection and Targeting the Cofilin Pathway Using an Anti-α4β7 Integrin Antibody SCIENCE ADVANCES 2019 5(1):0 SCI 12.804
IP-10 is highly involved in the HIV Infection CYTOKINE 2019 115():0 SCI 3.078
CircPUM1 promotes the malignant behavior of lung adenocarcinoma by regulating miR-326 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2019 508(3):0 SCI 2.705
Elevated Expression of miR-19b Enhances CD8(+) T Cell Function by Targeting PTEN in HIV Infected Long Term Non-progressors With Sustained Viral Suppression FRONTIERS IN IMMUNOLOGY 2019 9(3140):0 中文核心 4.716
High Polymorphism rates in well-known T cell epitopes restricted by pretective HLA alleles during HIV infection are associated with rapid disease progression in early- infected MSM in China MEDICAL MICROBIOLOGY AND IMMUNOLOGY 2019 208(2):0 SCI 2.96
Membrane metalloprotease TRABD2A restricts HIV-1 progeny production in resting CD4 + T cells by degrading viral Gag polyprotein NATURE IMMUNOLOGY 2019 20(6):0 SCI 23.53
Predictive effect of Body Mass Index on Immune Reconstitution among HIV-Infected HAART Users in China BMC infectious Disease 2019 19(1):0 SCI 2.565
Independent Severe Cases of Heterozygous Familial Hypercholesterolemia Caused by the W483X and Novel W483G Mutations in the Low-Density Lipoprotein Receptor Gene That Were Clinically Diagnosed as Homozygous Cases Genetic Testing and Molecular Biomarkers 2019 23(6):0 SCI 1.121
Development and Validation of a Personalized Social Media Platform–Based HIV Incidence Risk Assessment Tool for Men Who Have Sex With Men in China Journal of Medical Internet Research 2019 21(6):0 SCI 4.945
Reduced eIF3d accelerates HIV disease progression by attenuating CD8+ T cell function Journal of Translational Medicine 2019 17(1):0 SCI 4.098
我国男男性行为者HIV-1感染早期病毒分离株复制与疾病进展的关系 中国艾滋病性病 2018 24(8):0 中文核心 0
老年人类免疫缺陷病毒感染者抗病毒治疗疗效与预后分析 中华传染病杂志 2018 36(7):0 中文核心 0
家族性高胆固醇血症遗传因素筛查的研究进展 中国动脉硬化杂志 2018 26(11):0 中文核心 0
HIV潜伏库在CD4+T细胞亚群的分布及其免疫机制 免疫学杂志 2018 33(12):0 中文核心 0
High-risk behaviour and HIV infection risk among non-local men who have sex with men with less than a single year’s residence in urban centres:a multicentre cross-sectional study from China Sexually Transmitted Infections 2018 94(1):0 SCI 3.346
HIV Incidence and Care Linkage among MSM First-Time-Testers in Shenyang, China 2012-2014 AIDS and Behavior 2018 22(3):0 SCI 3.017
Female and younger subjects have lower adherence in PrEP trials: a meta-analysis with implications for the uptake of PrEP service to prevent HIV Sexually Transmitted Infections 2018 94():0 SCI 3.346
Interest in long-acting injectable PrEP in a cohort of men who have sex with men in China AIDS and Behavior 2018 22(4):0 SCI 3.017
Biological variation of serum neuron-specific enolase and carbohydrate antigen724 tumor markers JOURNAL OF CLINICAL LABORATORY ANALYSIS 2018 32(4):0 SCI 1.303
Poppers use and sexual partner concurrency increase the HIV incidence of MSM: a 24-month prospective cohort survey in Shenyang, China Scientific Reports 2018 8(1):0 SCI 4.122
AID recruits the RNA exosome to degrade HIV-1 nascent transcripts through interaction with the Tat-P-TEFb-TAR RNP complex FEBS LETTERS 2018 592(2):0 SCI 2.999
Intimate Partner Violence Correlates With A Higher HIV Incidence Among MSM: A 12-Month Prospective Cohort Study in Shenyang, China Scientific Reports 2018 8(1):0 中文核心 4.122
IL-10+NK and TGF-β+ NK cells play negative regulatory roles in HIV infection BMC Infectious Disease 2018 18(1):0 SCI 2.62
Alteration of CCR6+CD59+CD4+ Naïve T cell in HIV-1 Infected Patients: Implication for Clinical Practice Cellular Immunology 2018 327():0 SCI 2.995
Plasma metabolic changes in Chinese HIV-infected patients receiving lopinavir/ritonavir based treatment: Implications for HIV precision therapy Cytokine 2018 110():0 SCI 3.514
First cases and risk factors of super yeast Candida auris infection or colonization from Shenyang, China Emerging Microbes & Infections 2018 7(1):0 SCI 6.032
HIV incidence is rapidly increasing with age among young men who have sex with men: a multicentre cross-sectional survey in China HIV MEDICINE 2018 19(8):0 SCI 3.734
The Early Antibody-Dependent Cell-Mediated Cytotoxicity Response is Associated with Lower Viral Set Point in Individuals with Primary HIV Infection FRONTIERS IN IMMUNOLOGY 2018 9():0 SCI 4.716
Expression of the Inhibitory Receptor TIGIT is Up-Regulated Specifically on NK Cells with CD226 Activating Receptor from HIV-Infected Individuals FRONTIERS IN IMMUNOLOGY 2018 9(2341):0 SCI 4.716
The Effect of Using Geosocial Networking Apps on the HIV Incidence Rate Among Men Who Have Sex With Men: Eighteen-Month Prospective Cohort Study in Shenyang, China JOURNAL OF MEDICAL INTERNET RESEARCH 2018 20(12):0 SCI 4.945
V4 region of the envelope gene mediates immune escape during early HIV-1 infection but fails to induce broadly neutralizing antibodies VACCINE 2018 36(50):0 SCI 3.269
Research on the treatment effects and drug resistances of Long-term second-line antiretroviral therapy among HIV-infected patients from Henan Province in China BMC INFECTIOUS DISEASE 2018 18(571):0 SCI 2.565
Increased expression of sST2 in early HIV infected patients attenuated the IL-33 induced T cell responses FRONTIERS IN IMMUNOLOGY 2018 9(2857):0 SCI 4.716
Crosstalk in competing endogenous RNA networks reveals new circular RNAs involved in the pathogenesis of early HIV infection JOURNAL OF TRANSLATIONAL MEDICINE 2018 16(332):0 SCI 4.098
M-DC8+树突状细胞（slanDC）与 HIV 感染研究进展 免疫学杂志 2017 33(2):0 中文核心 0
我国HIV/AIDS病人接受二线抗反转录病毒治疗长期疗效评价 中国艾滋病性病杂志 2017 223(9):0 SCI 0
沈阳市15-30岁学生HIV/AIDS患者抗病毒治疗相关因素分析 中华流行病学杂志 2017 38(8):0 中文核心 0
Dual infection contributes to rapid disease progression in men who have sex with men in China: An acute HIV-1 infection prospective cohort study JAIDS 2017 74(5):0 SCI 3.935
Elevated interferon-gamma-induced protein 10 and its receptor CXCR3 impair NK cell function during HIV infection Journal of Lleukocyte Biology 2017 102(1):0 SCI 4.224
Myeloid-Derived Suppressor Cells Associated With Disease Progression in Primary HIV Infection: PD-L1 Blockade Attenuates Inhibition JAIDS 2017 76(2):0 SCI 4.116
The investigation of CD4+T cell functions in primary HIV infection with antiretroviral therapy Medicine 2017 96(28):0 SCI 2.028
Near Full-Length Genome Sequence of a Novel HIV-1 Second-Generation Recombinant Form (CRF01_AE/CRF07_BC) Detected among Blood Donors in North China AIDS Research and Human Retroviruses 2017 33(12):0 SCI 1.935
Deregulated MicroRNA-21 Expression in Monocytes from HIV-Infected Patients Contributes to Elevated IP-10 Secretion in HIV Infection Frontiers in immunology 2017 8():0 SCI 5.511
Transcriptomic meta-analysis identifies gene expression characteristics in various samples of HIV-infected patients with nonprogressive disease Journal of Translational Medicine 2017 15(1):0 SCI 4.197
NKG2C(+)NKG2A(-) Natural Killer Cells are Associated with a Lower Viral Set Point and may Predict Disease Progression in Individuals with Primary HIV Infection Frontiers in immunology 2017 8():0 SSCI 5.511
Chemokines and Chemokine Receptors: Accomplices for Human Immunodeficiency Virus Infection and Latency Frontiers in immunology 2017 8():0 SCI 5.511
FOXO3, IRF4, and xIAP are Correlated with Faster Disease Progression in HIV-1-Infected Men Who Have Sex with Men AIDS Research and Human Retroviruses 2017 33(2):0 SCI 2.095
CD4+IL-21+T cells correlated with regulatory T cells and IL-21 promoted regulatory T cells survival in HIV infection CYTOKINE 2017 91():0 SCI 3.488
Prevalence and determinants of HSV-2/syphilis co-infection and HSV-2 mono-infection among HIV-positive men who have sex with men: a cross-sectional study in Northeast China JAPANESE JOURNAL OF INFECTIOUS DISEASES 2017 70(3):0 SCI 1.273
Treatment-seeking behavior and barriers to accessing services for sexually transmitted diseases among men who have sex with men in China: a multicenter cross-sectional survey Infectious Diseases of Poverty 2017 6(1):0 SCI 3.181
河南省某县获得性免疫缺陷综合征患者二线抗病毒疗效及耐药变异分析 中华实验和临床感染病杂志 2017 8(11):0 中文核心 0
蛋白质结构限制性对HIV-1耐药相关基因分子进化规律的影响研究 中华微生物学和免疫学杂志 2016 36(6):0 CSCD 0
HIV-1感染者T细胞分泌TGF-β和IL-10水平及其抑制作用的研究 免疫学杂志 2016 32(9):0 CSCD 0
HIV incidence and associated risk factors in men who have sex with men (MSM) in Mainland China: an updated systematic review and Meta-analysis SEXUAL HEALTH 2016 13(4):0 SCI 1.238
A Novel HIV-1 Second-Generation Recombinant Form (CRF01_AE/CRF07_BC) among heterosexuals in Nei Monggoi Autonomous Region and A Summary of Present Seven Such Recombinants in China AIDS Research and Human Retroviruses 2016 32(8):0 SCI 2.095
The Role of HIV-1 in Affecting the Proliferation Ability of Hematopoietic Progenitor Cells (HPCs) Derived from Bone Marrow (BM) JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIE 2016 71(5):0 SCI 3.935
Spatiotemporal hierarchy in antibody recognition against transmitted HIV-1 envelope glycoprotein during natural infection Retrovirology 2016 13(1):0 SCI 3.867
HPV16 E6 upregulates Aurora A expression ONCOLOGY LETTERS 2016 12():0 SCI 1.39
Correlation between baseline hormonal disorders in male HIV patients with follow-up immunological failure and mortality HIV Medicine 2016 95(52):0 SCI 3.257
Commercial sex and risk of HIV, syphilis, and herpes simplex virus-2 among men who have sex with men in six Chinese cities BMC Infectious Disease 2016 16(1):0 SCI 2.768
Decreasing age at first anal intercourse among men who have sex with men in China: a multicentre cross-sectional survey Journal of the International AIDS Society 2016 19(1):0 SCI 6.296
Multi-layered Gag-specific immunodominant responses contribute to better disease control in CRF01_AE subtype HIV-1 infected MSM subjects BMC Immunology 2016 17(1):0 SCI 2.485
High HIV Incidence Epidemic among Men Who Have Sex with Men in China: Results from a multi-site cross-sectional study Infectious Diseases of Poverty 2016 5(1):0 SCI 3.181
Lipids profile among ART-naïve HIV infected patients and men who have sex with men in China: a case control study Lipids in Health and Disease 2016 15(1):0 SCI 2.073
近10年亲密伴侣暴力国际研究热点的文献计量学分析 中华医学杂志 2015 95(36):0 CSCD 0
Reference Intervals of Serum Sodium, Potassium, and Chlorine in Chinese Han Population and Comparison of Two ISE Methods JOURNAL OF CLINICAL LABORATORY ANALYSIS 2015 29(3):0 SCI 1.594
实时定量PCR检测KIR转录水平的方法构建 中国实验诊断学 2015 19(12):0 CSCD 0
Multi-layered Gag-Specific T Cell Responses Contribute to Slow Disease Progression in HIV-1-Infected HLA-A*30-B*13-C*06-Positive Individuals AIDS 2015 29(9):0 SCI 4.407
The proportion and trend of human immunodeficiency virus infections associated with men who have sex with men from Chinese voluntary blood donors: a systematic review and meta-anal TRANSFUSION 2015 55(3):0 SCI 3.042
肺炎链球菌的侵袭性与耐药性比较分析 临床检验杂志 2015 33(2):0 CSCD 0
The biological characteristics of predominant strains ofHIV-1genotype: Modeling of HIV-1 infection among men who have sex with men Journal of Medical Virology 2015 87(4):0 SCI 1.998
Urine alpha1-microglobulin is a better marker for early tubular dysfunction than beta2-microglobulin among tenofovir-exposed human immunodeficiency virus-infect Brazilian Journal of Infectious Diseases 2015 19(4):0 SCI 1.412
Genome-Wide Association Studies of HIV-1 Host Control in Ethnically Diverse Chinese Populations SCIENTIFIC REPORTS 2015 3(5):0 SCI 5.228
Increase of RT-Related Transmitted Drug Resistance in Non-CRF01_AE Among HIV Type 1-Infected Men Who Have Sex With Men in 7 Cities of China JAIDS 2015 68(3):0 SCI 4.394
Complete Blood Count Reference Intervals for Healthy Han Chinese Adults PLOS ONE 2015 10(3):0 SCI 3.057
Reduced bone mineral density among ART-naive male patients with HIV in China Future Virology 2015 10(7):0 SCI .886
A Large-scale Survey of CRF55_01B from Men-Who-Have-Sex-with-Men in China: implying the Evolutionary History and Public Health Impact SCIENTIFIC REPORTS 2015 15(5):0 SCI 5.228
Association of Hippocampal Magnetic Resonance Imaging with Learning and Memory Deficits in HIV-1 Seropositive Patients JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIE 2015 70(4):0 SCI 4.394
Sexual Risk Behaviors and HIV Infection among Men Who Have Sex with Men and Women in China: Evidence from a Systematic Review and Meta-Analysis BIOMED RESEARCH INTERNATIONAL 2015 2015():0 SCI 2.134
Rapid Diagnostic Tests for Identifying Avian Influenza A(H7N9) Virus in Clinical Samples EMERGING INFECTIOUS DISEASES 2015 21(1):0 SCI 6.994
Elevation of Tim-3 and PD-1 Expression on T Cells Appears Early in HIV Infection, and Differential Tim-3 and PD-1 Expression Patterns Can Be Induced by Common gamma-Chain Cytokines Biomed Research International 2015 916936():0 SCI 2.134
MSM and HIV-1 infection in China National Science Review 2015 2():0 SCI 8
Thymic Function Is Most Severely Impaired in Chronic HIV-1 Infection, but Individuals With Faster Disease Progression During Early HIV-1 Infection Expressed Lower Levels of RTEs JAIDS 2015 70(5):0 SCI 4.394
Low CD1c+myeloid dendritic cell counts correlated with a high risk of rapid disease progression during early HIV-1 infection BMC INFECTIOUS DISEASES 2015 15():0 SCI 2.69
Herpes Virus Entry Mediator, which Decreases in HIV Infection, Can Enhance the Suppressive Activity of Regulatory T Cell and Predict Recovery of CD4+T-cells During HAART CURRENT HIV RESEARCH 2015 13(2):0 SCI 1.562
Investigation on Reference Intervals and Regional Differences of Platelet Indices in Healthy Chinese Han Adults JOURNAL OF CLINICAL LABORATORY ANALYSIS 2015 29(1):0 SCI 1.549
The Effect of Thalassemia on Erythrocyte Reference Intervals in a Representative Han Chinese Adult Population CLINICAL LABORATORY 2015 61():0 SCI .936
Changes in B-Cell Counts and Percentages during Primary HIV Infection Associated with Disease Progression in HIV-Infected Men Who Have Sex with Men: A Preliminary Study BIOMED RESEARCH INTERNATIONAL 2015 468194():0 SCI 2.134
Complete blood count reference intervals and age-and sex-related trends of North China Han population CLINICAL CHEMISTRY AND LABORATORY MEDICINE 2014 52(7):0 SCI 2.19
Recreational drug use and risks of HIV and sexually transmitted infections among Chinese men who have sex with men: Mediation through multiple sexual partnerships BMC INFECTIOUS DISEASES 2014 14():0 SCI 1.868
Risk factors associated with prevalent and incident syphilis among an HIV-infected cohort in Northeast China BMC INFECTIOUS DISEASES 2014 14():0 SCI 1.868
Discordance between genotypic resistance and pseudovirus phenotypic resistance in AIDS patients after long-term antiretroviral therapy and virological failure JOURNAL OF BASIC MICROBIOLOGY 2014 54(10):0 SCI 1.823
Human Papillomavirus 16 E6 Contributes HIF-1 alpha Induced Warburg Effect by Attenuating the VHL-HIF-1 alpha Interaction INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2014 15(5):0 SCI 2.862
2011年度全国细菌耐药监测报告：65岁以上老年患者细菌耐药监测 中国临床药理学杂志 2014 30(2):0 CSCD 0
HIV阳性MSM HSV-2感染及危险因素调查 中国公共卫生 2014 30(3):0 CSCD 0
The fuction of CD3+CD56+ NKT-like cells in HIV-infected individuals BioMed Research International 2014 3(20):0 SCI 1.868
General peroxidase activity of a parallel G-quadruplex-hemin DNAzyme formed by Pu39WT - a mixed G-quadruplex forming sequence in the Bcl-2 P1 promoter Chemistry Central Journal 2014 8(43):0 SCI 2.187
Identification and Characterization of a Novel HIV-1 Circulating Recombinant Form (CRF59_01B) identified among men-who-have-sex-with-men in China PLoS ONE 2014 9(6):0 SCI 3.234
Prevalence and predictors of HIV among Chinese tuberculosis patients by provider-initiated HIV testing and counselling (PITC): A multisite study in south central of China PLoS ONE 2014 9(2):0 SCI 3.234
Treatment effect and drug-resistant mutations in Chinese AIDS patients switching to second-line antiretroviral therapy PLoS ONE 2014 9(10):0 SCI 3.234
HIV, hepatitis B virus, and hepatitis C virus co-infection in patients in the China National Free Antiretroviral Treatment Program, 2010-12: a retrospective observational cohort study Lancet Infectious Diseases 2014 14(11):0 SCI 22.433
国际酶学参考实验室室间比对四种酶学项目结果分析 中华检验医学杂志 2014 37(5):0 CSCD 0
非参数分位数回归模型在医学参考区间建立中的应用 中国卫生统计 2014 31(3):0 CSCD 0
免疫渗滤法检测血液及尿液HIV抗体的应用评价 微生物学杂志 2014 34(3):0 CSCD 0
三种四代HIV筛查试剂检测窗口期的差异研究 中华检验医学杂志 2014 37(8):0 CSCD 0
蒙特利尔认知评估量表评价人类免疫缺陷病毒感染者神经认识功能及其与高效抗反转录病毒治疗的效果 中华传染病杂志 2014 32(7):0 CSCD 0
High prevalence of HIV infection and unprotected anal intercourse among older men who have sex with men in China: A systematic review and meta-analysis. BMC Infectious Disease 2014 14():0 SCI 1.868

著作(近5年)
专著名称 出版社 出版年 承担职务 主编人数
艾滋病抗病毒治疗实用手册 人民卫生出版社 2015 主编 1
全国临床检验操作规程 第4版 人民卫生出版社 2015 主编 3
实验诊断学 第3版 人民卫生出版社 2015 主编 2
艾滋病抗病毒治疗实践 人民卫生出版社 2015 主编 1
实验诊断学病案、习题及实习指导 第2版 人民卫生出版社 2015 主编 3
实验诊断学 供临床型研究生及专业医师用 人民卫生出版社 2014 主编 2

专利(近5年)
专利名称 专利类别 获得年 负责人排序
暂无

科研奖励(近5年)
奖励名称 奖励级别 获奖年 负责人排序
辽宁省科学技术进步奖 一等奖 2017 1
国家科学技术进步奖 二等奖 2015 1
辽宁省科学技术进步奖 一等奖 2014 1