刘钊
硕士生导师

职称：副主任医师

学院：第一临床医学院
xylzhao9999@163.com







个人简介
本人曾于美国德克萨斯州立大学圣安东尼奥医学中心（UTHSCSA）从事乳腺疾病相关研究近3年。 目前主持国家自然科学基金1项，徐医附院优秀博士启动基金1项，参与江苏省自然科学基金1项，徐州市科技项目1项。曾经获得江苏省普通高校研究生科研创新计划资助1项，以排名第2身份参与国家自然科学基金面上项目1项。目前发表相关论文10篇，其中以第一作者身份发表SCI论文5篇。






科研项目（近五年）

NONHSAT087648/BHLHE40在化疗诱导乳腺癌细胞发生EMT中的机制研究国家自然科学基金17万
徐州医科大学附属医院优秀博士启动基金 30万
博士后基金 6万

论文情况（近五年）
1. Lidong Ren#, Zhao Liu#(并列第一作者), Mendi Liang, Li Wang, Xingli Song, Shui Wang. 10% fluorescein sodium vs 1% isosulfan blue in breast sentinel lymph node biopsy. World J Surg Oncol. 2016 Nov 3;14(1):280. （IF 1.286）2. Zhao Liu, Long Wang, Junhua Yang, Abhik Bandyopadhyay, Virginia Kaklamani, Shui Wang, Lu-Zhe Sun. Estrogen receptor alpha inhibits senescence-like phenotype and facilitates transformation induced by oncogenic ras in human mammary epithelial cells. Oncotarget.2016 Jun 1. doi: 10.18632/oncotarget.9772.（IF5.168）3. Xingli Song, Mengdi Liang, Wenbin Zhou, Lidong Ren, Zhao Liu, Guo Wang, Qi Wei, Shui Wang*. Doxorubicin hydrochloric increases tumour coagulation and end-point survival in percutaneous microwave ablation of tumours in a VX2 rabbit tumour model.Int J Hyperthermia. 2016 Feb 24:1-7.
4. Zhao Liu, Lidong Ren, Chenghao Liu, Tiansong Xia, Xiaoming Zha*, Shui Wang*. Phenformin Induces Cell Cycle Change, Apoptosis, and Mesenchymal-Epithelial Transition and Regulates the AMPK/mTOR/p70s6k and MAPK/ERK Pathways in Breast Cancer Cells. PLoS One. 2015 Jun 26;10(6):e**. （IF3.057）
5. Keya De Mukhopadhyay#, Zhao Liu# (并列第一作者), Rajeshwar R. Tekmal Rong Li, Ratna K.Vadlamudi, Shui Wang*, Lu-zhe Sun*. Aromatase expression increases the survival and malignancy of estrogen receptor positive breast cancer cells. PLoS One. 2015 Apr 2;10(4):e**（IF3.057）
6. Zhao Liu , Jiajie Hou , Lidong Ren , Jing He , Beicheng Sun , Lu-zhe Sun , Shui Wang*. Protein tyrosine phosphatase receptor type O expression in the tumor niche correlates with reduced tumor growth,angiogenesis, circulating tumor cells and metastasis of breast cancer. Oncology Report.2015 , 33(4):1908-1914. （IF2.486）
7. 王水*, 刘钊. 乳腺神经内分泌癌. 中国实用外科学杂志. 2013, (3): 238-240.
8. Zhao Liu, Abhik Bandyopadhyay, Robert W. Nichols, Long Wang, Andrew P. Hinck, Shui Wang and Lu-Zhe Sun*. Blockade of Autocrine TGF-β Signaling Inhibits Stem Cell Phenotype, Survival, and Metastasis of Murine Breast Cancer Cells. J Stem Cell Res Ther 2012,19; 2 (1):1-8.
9. Shu Lin, LanYu, Junhua Yang, Zhao Liu, Bijal Karia , Alexander J.R.Bishop, James Jackson, Guillermina Lozano, John A. Copland, Xiaoxin Mu, Beicheng Sun and Lu-zhe Sun*. Mutant p53 disrupts the role of Shc A in balancing the Smad-depenent and independent signaling activity of transforming growth factor-beta. J Biol Chem 2011, 286(51): 44023-44034.






发表论文:
Increased Stromal Infiltrating Lymphocytes are Associated with Circulating Tumor Cells and Metastatic Relapse in Breast Cancer Patients After Neoadjuvant Chemotherapy

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Estrogen receptor alpha inhibits senescence-like phenotype and facilitates transformation induced by oncogenic ras in human mammary epithelial cells.

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10 % fluorescein sodium vs 1 % isosulfan blue in breast sentinel lymph node biopsy.

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Phenformin Induces Cell Cycle Change, Apoptosis, and Mesenchymal-Epithelial Transition and Regulates the AMPK/mTOR/p70s6k and MAPK/ERK Pathways in Breast Cancer Cells.

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Protein tyrosine phosphatase receptor type O expression in the tumor niche correlates with reduced tumor growth, angiogenesis, circulating tumor cells and metastasis of breast cancer.

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Aromatase expression increases the survival and malignancy of estrogen receptor positive breast cancer cells.

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Blockade of Autocrine TGF-β Signaling Inhibits Stem Cell Phenotype, Survival, and Metastasis of Murine Breast Cancer Cells.
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