王允
硕士生导师

职称：副教授

学院：药学院
wangyun@xzhmu.edu.cn







个人简介
2006年7月毕业于泰山医学院药学专业，获医学学士学位。2009年7月毕业于徐州医科大学药理学专业，获医学硕士学位。2016年6月毕业于苏州大学药理学专业，获医学博士学位。2009年9月至今在徐州医科大学药理学教研室从事教学与科研工作，以第一作者发表SCI论文多篇；主持国家自然科学基金青年科学基金项目、中国博士后基金面上项目、江苏省博士后基金、徐州市科技计划项目等各1项。目前研究方向为：神经精神药理学。

论文情况（近五年）

1.Wang Y,Gao C,Gao T,Zhao L,Zhu S,Guo L.Plasma exosomes from depression ameliorate inflammation-induced depressive-like behaviors via sigma-1 receptor delivery.Brain Behav Immun. 2021. doi: 10.1016/j.bbi.2021.02.004. Online ahead of print.
2.Wang Y,Ni J, Gao T, Gao C, Guo L, Yin X. Activation of astrocytic sigma-1 receptor exerts antidepressant-like effect via facilitating CD38-driven mitochondria transfer.Glia. 2020.68(11):2415-2426.
3.Wang Y, Ni J, Gao C, Xie L, Zhai L, Cui G, Yin X. Mitochondrial transplantation attenuates lipopolysaccharide- induced depression-like behaviors.Prog Neuropsychopharmacol Biol Psychiatry. 2019. 93:240-249.
4.Wang Y, Ni J, Zhai L, Gao C, Xie L, Zhao L, Yin X. Inhibition of activated astrocyte ameliorates lipopolysaccharide- induced depressive-like behaviors.J Affect Disord. 2019. 242:52-59
5.Wang Y,Jiang H, Ni J, Guo L. Pharmacological stimulation of sigma-1 receptor promotes activation of astrocyte via ERK1/2 and GSK3β signaling pathway.Naunyn Schmiedebergs Arch Pharmacol. 2019. 392:801-812.






发表论文:
Activation of astrocytic sigma-1 receptor exerts antidepressant-like effect via facilitating CD38-driven mitochondria transfer

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Mitochondrial transplantation attenuates lipopolysaccharide- induced depression-like behaviors.

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Astrocytes activation contributes to the antidepressant-like effect of ketamine but not scopolamine.

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Allosteric modulation of sigma-1 receptors elicits rapid antidepressant activity
教材专著:

科研项目:
线粒体动力学调控的星形胶质细胞

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基于自体单核细胞诱导的小胶质细
获奖成果: