张赭
博士生导师

职称：教授

学院：麻醉学院







个人简介





发表论文:
A limited access compartment between the pore domain and cytosolic domain of the BK channel.

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Nerve growth cone guidance mediated by G protein-coupled receptors

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Coronin 6 Regulates Acetylcholine Receptor Clustering through Modulating Receptor Anchorage to Actin Cytoskeleton

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Structural determinants of phosphatidylinositol 4,5-bisphosphate (PIP2) regulation of BK channel activity through the RCK1 Ca2+ coordination site

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Epilepsy-Related Slack Channel Mutants Lead to Channel Over-Activity by Two Different Mechanisms

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The RCK2 domain utilizes a coordination site present in Kir channels to confer sodium sensitivity to Slo2.2 channels.

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Phosphatidylinositol (4,5)-Bisphosphate (PIP2) Activates Slo3 Currents and its Hydrolysis Underlies the EGF-Induced Current Inhibition

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A sodium-mediated structural switch that controls the sensitivity of Kir channels to PtdIns(4,5)P2

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Block of mouse Slo1 and Slo3 K+ channels by CTX, ibTX, TEA, 4-AP and quinidine

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SLO-2 isoforms with unique Ca(2+) - and voltage-dependence characteristics confer sensitivity to hypoxia in C. elegans.
教材专著:

科研项目:
Slack 通道癫痫相关突变体在额叶

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KCNT1通道在氟烷类麻醉剂和丙泊

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Slack 通道调控GABAa 受体介导全

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KCNT1通道参与的全身麻醉神经环

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医学科学

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Slack 通道癫痫相关突变体在额叶

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Slack 通道参与GABAa 受体介导全

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KCNT1通道在氟烷类麻醉剂和丙泊
获奖成果:
癫痫相关Slack通道突变体通过两

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癫痫相关Slack通道突变体通过两