【教育背景和工作经历】
2017/01～2018/01，新加坡南洋理工大学，生物科学学院，省公派访问****
2014.12～至今，江苏大学，药学院，硕士生导师
2014/07～至今，江苏大学，药学院，副教授
2007/08～2014/06，江苏大学，药学院，讲师
2002/09～2007/07，江苏大学，药学院，助教
2012/09～2019/09，江苏大学，临床检验诊断学，博士
2002/09～2005/06，江苏大学，生药学，硕士
1998/09～2002/06，江苏大学，药学，学士
【科研项目】
[1] 国家自然科学基金面上项目，构建新型高效酶水解体系以获取中药活性成分的研究（**），2019.01-2022.12，56万元，在研，主持
[2] 国家自然科学基金面上项目，基于特异蛋白发现的胶类中药专属性鉴定研究（**），2018.01-2021.12，55万元，在研，参加
[3] 江苏省自然科学基金，基于NanoLC-Orbitrap MSD技术鉴定胶类中药的研究（BK**），2015.07-2018.07，20万元，已结题，参加
[4] 国家自然科学基金青年项目，MALDI-TOF/TOF-MS解析动物药中标志蛋白质和多肽作为特征识别物的研究（**），2014.01-2016.12，23万元，已结题，主持
[5] 国家自然科学基金青年项目，共价固定化酶循环利用于高效催化产生中药活性成分的研究（**），2014.01-2016.12，23万元，已结题，参加
[6] 江苏省自然科学基金青年项目，五种动物药鉴定中标志蛋白和多肽特征识别物的研究（BK**），2012.07-2015.07，20万元，已结题，参加
[7] 国家自然科学基金青年项目，基于多层次物质基础的三七蒸制机理研究（**），2012.01-2014.12，22万元，已结题，参加
[8] 国家自然科学基金面上项目，难溶药物新型胶束载体的构建及其增溶机理研究（**），2005.01-2007.12，20万元，已结题，参加
【代表性SCI论文 2015～】
[1] Ling Lin, Yajie Zhang, Ye Li, Haizhen Fu, Jianhui Hu, Ying Zhou, Ying Xu, Guohua Xia, Xiaoxiang Sun, Huan Yang*, Yuping Shen*. Identification of signature proteins of processed Bombyx batryticatus by comparative proteomic analysis [J]. International Journal of Biological Macromolecules, 2020, 153: 289-296.
[2] Yaya Yang, Yang Zheng, Beibei Lu, Zhaoqun Jiao, Liqun Chen, Roselyn Tehzee Gblinwon, Xiaobin Jia, Yuping Shen*, Huan Yang*. Rapid identification of Cervus antlers by species-specific PCR assay [J]. Natural Product Research, 2020, 34(9): 1315-1319.
[3] Huan Yang, Ying Zhou, Pingtian Yu, Yaya Yang, Zhaoqun Jiao, James P. Tam, Yuping Shen*, Xiaobin Jia*. A novel PCR-based technology for rapid and non-sequencing authentication of Bombyx batryticatus using species-specific primers [J]. Natural Product Research, 2019, 33(9): 1251-1256.
[4] Changjie Yu, Zihao Li, Huawu Yin, Guohua Xia, Yuping Shen*, Huan Yang*, Jing Gao. Green production of diosgenin from Discorea nipponica Makino based on pressurized biphase acid hydrolysis via response surface methodology optimization [J]. Green Chemistry Letters and Reviews, 2019, 12(1): 79-88.
[5] Yang Zheng, Beibei Lu, Yaya Yang, Zhaoqun Jiao, Liqun Chen, Pingtian Yu, Yuping Shen*, Huan Yang*. Rapid identification of medicinal leech by species-specific PCR technology [J]. Pharmacognosy Magazine, 2019, 15(63): 410-415.
[6] Yuping Shen, Minhui Xu, Yufei Chen, Haiyan Wang, Yiying Zhou, Yeting Zhu, Huan Yang*, Jiangnan Yu*. Integrated extraction and purification of total bioactive flavonoids from Toona sinensis leaves [J]. Natural Product Research, 2019, 33(20): 3025-3028.
[7] Yuping Shen, Yi Lu, Jing Gao, Yeting Zhu, Man Wang, Shunli Jing, Lili Xu, Huan Yang*, Xiaobin Jia*. Efficient preparation of rare Sagittatoside A from Epimedin A, by recyclable aqueous organic two-phase enzymatic hydrolysis [J]. Natural Product Research, 2019, 33(21): 3095-3102.
[8] Yuping Shen, Man Wang, Yufei Chen, Lili Xu, Yi Lu, Yiying Zhou, James P. Tam, Feng Han, Huan Yang*, Xiaobin Jia*. Convenient preparation of sagittatoside B, a rare bioactive secondary flavonol glycoside, by recyclable and integrated biphase enzymatic hydrolysis [J]. Enzyme and Microbial Technology, 2019,121:51-58.
[9] Yuping Shen, Lili Xu, Jiayi Huang, Aida Serra, Huan Yang, James P. Tam*. Potentides: new cysteine-rich peptides with unusual disulfide connectivity from Potentilla anserina [J]. ChemBioChem, 2019, 20(15): 1995-2004.
[10] Liqun Chen, Zhaoqun Jiao, Yufei Chen, Pingtian Yu, Yang Zheng, Yaya Yang, Yuping Shen*, Huan Yang*. Development of a species-specific PCR-based technology for authentication of Asini Corii Colla and Taurus Corii Colla [J]. Pharmacognosy Magazine, 2019, 15(65): 607-612.
[11] Yufei Chen, Yaya Yang, Yinhuan Qian, Roselyn Tehzee Gblinwon, Jiao Zhaoqun, Liqun Chen, Ling Lin, Yang Zheng, Huan Yang*, Yuping Shen*. Harnessing multiplex PCR assay targeting specific mitochondrial DNA elements for simultaneous identification of antelope species in Cornu Saigae Tataricae [J]. Mitochondrial DNA Part B: Resources, 2019, 4(2): 3222-3226.
[12] Yuping Shen+, Man Wang+, Jinwei Zhou+, Yufei Chen, Lili Xu, Mengru Wu, Guohua Xia, James P. Tam, Jiangnan Yu, Xiying Teng, Huan Yang*, Xiaobin Jia*. Eco-efficient Biphasic Enzymatic Hydrolysis for the Green Production of Rare Baohuoside I [J]. Enzyme and Microbial Technology, 2019, 131: 109431.
[13] Huan Yang, Ying Zhou, Pingtian Yu, Yaya Yang, Zhaoqun Jiao, James P. Tam, Yuping Shen*, Xiaobin Jia*. A novel PCR-based technology for rapid and non-sequencing authentication of Bombyx batryticatus using species-specific primers [J]. Natural Product Research, 2019, 33(9): 1251-1256.
[14] Huan Yang, Pingtian Yu, Yi Lu, Zhaoqun Jiao, Liqun Chen, Ying Zhou, Yuping Shen*, Xiaobin Jia*. A novel non-sequencing approach for rapid authentication of Testudinis Carapax et Plastrum and Trionycis Carapax by species-specific primers [J]. Royal Society Open Science, 2018, 5: 172140.
[15] Yuping Shen, Minhui Xu, Peipei Deng, Qinying Gu, Huawu Yin, Guohua Xia, Xiaobin Jia*, Huan Yang*, James Tam. Establishment of a rapid method to quantify eight flavonol glycosides for quality assessment of Red Toon using UPLC [J]. Acta Chromatographica, 2018, 30(1): 31-37.
[16] Yuping Shen#, Haiyan Wang#, Yi Lu#, Lili Xu, Huawu Yin, James P. Tam, Huan Yang*, Xiaobin Jia*. Construction of a novel catalysis system for clean and efficient preparation of Baohuoside I from Icariin based on biphase enzymatic hydrolysis [J]. Journal of Cleaner Production, 2018, 170: 727-734. （IF 6.395, Q1)
[17] Huan Yang, Jie Zheng, Haiyan Wang, Nan Li, Yaya Yang, Yuping Shen*. Comparative proteomic analysis of three gelatinous Chinese medicines and their authentications by tryptic-digested peptides profiling using MALDI-TOF/TOF-MS [J]. Pharmacognosy Magazine, 2017, 13(52): 663-667.
[18] Huan Yang, Huawu Yin, Yuping Shen*, Guohua Xia, Bo Zhang, Xiangyang Wu, Baochang Cai*, James P. Tam. A more ecological and efficient approach for producing diosgenin from Dioscorea zingiberensis tubers via pressurized biphase acid hydrolysis [J]. Journal of Cleaner Production, 2016, 131: 10-19.
[19] Huan Yang, Yuping Shen, Ying Xu, Aida Maqueda, Jie Zheng, Qinan Wu*, James P. Tam*. A novel strategy for the discrimination of gelatinous Chinese medicines based on enzymatic digestion followed by nano-flow liquid chromatography in tandem with orbitrap mass spectrum detector [J]. International Journal of Nanomedicine, 2015, 10: 4947-4955. (IF 5.029, Q1)
【国家发明专利】
[1] 杨欢，沈玉萍，顾芹英，周存山，夏国华，孙竞. 一种香椿叶中没食子酸及其甲酯的同时制备及检测方法. 2014.12.24授权，ZL9.5
[2] 沈玉萍，杨欢，夏国华，周存山，王海艳，卢艺. 一种双相酶水解获取宝藿苷I的方法. 2020.6.26 授权，ZL9.8
[3] 沈玉萍，杨欢，徐莹，余江南，陈慧卿，曹进，夏国华. 一种利用生物质谱技术快速检测僵蚕蛋白质的方法. 2015.12.30公开，CNA
【研究生培养】
指导生药学研究生6名，重视培养学生的国际化视野，课题组专门设立基金，
承担研究生出国交流、语言培训与考试等费用。
2019 年，指导的两位研究生成功获批CSC全额奖学金资助，分别前往法国皮
埃尔结构生物学研究所、德国亚琛工业大学攻读博士学位。
组织所指导研究生多次赴新加坡、日本参加国际会议，并做墙报展示。
【联系方式】
办公室：药学楼2205室
实验室：药学楼2514-2518室
Email：syp131@ujs.edu.cn
2020年7月12日更新
