江苏大学副教授，2014年获得浙江大学药学院博士学位，于2016年—2018年在美国佐治亚理工学院（Georgia Institute of Technology）进行为期2年的访学研究，主要从事智能靶向载体的构建及评价、新型肿瘤治疗技术、肿瘤成像及诊断技术等方向的研究工作，先后承担国家自然科学基金、江苏省自然科学基金、中国博士生后基金特别资助和一等资助、江苏省博士后基金、江苏省高校自然科学基金等多个项目。在Angew. Chem. Int. Ed (IF: 12.3)., Nano lett. (IF: 12.3), Small (IF: 10.8), Biomaterials (IF: 10.8), Nanoscale (IF: 7.2)等期刊发表SCI论文30余篇。
Email: jsdx.shensong@163.com
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欢迎具有化学、材料或生物医学背景的同学报考！
研究项目：
[1] 主持国家自然科学基金：pH/NIR双重智能响应系统靶向联合治疗类风湿关节炎的研究，项目号：**，起止时间：2016.1-2018.12。
[2] 主持江苏省自然科学基金：pH/NIR智能响应系统治疗类风湿关节炎的作用机制研究，项目号：BK**，起止时间：2016.1-2018.12。
[3] 主持中国博士后基金项目（特别资助）：磁性分子印迹聚合物用于肠道内毒素特异识别及清除研究，项目号：2016T90433，起止时间：2016.3-2018.3
[4] 主持中国博士后基金项目（一等资助）：基于氧化铁的诊断治疗系统在类风湿关节炎中的应用，项目号：2015M580404，起止时间：2014.7-2016.6
[5] 主持江苏省博士后基金项目：线粒体靶向给药系统的构建及其在肿瘤声动力治疗中的应用，项目号：**B，起止时间：2014.12-2016.11。
[6] 主持江苏大学高级人才科研启动基金：Yolk-Shell结构的光触发释药系统的构建及其光热-化疗联合抗肿瘤应用研究，项目号：14JDG181，起止时间：2014.7-2016.6。
[7] 主持江苏省教育厅高校自然科学基金：基于Fe3O4的智能光控给药系统的构建及应用研究，项目号：15KJB350001，起止时间：2015.7-2017.6.
[8] 参与国家自然科学基金：新型多功能碳纳米管基因传递系统的构建及性能研究，项目号：**，起止时间：2012.1~2015.12。
[9] 参与国家自然科学基金：TRAIL介导基于无机材料的层次化双重靶向肿瘤联合治疗给药系统构建及机制研究，项目号：**，起止时间：2014.1~2017.12。
近5年发表论文（仅列出一作及通讯作者文章）：
[19] Song Shen*, Lei Feng, Shunyao Qi, Jin Cao, Yanru Ge, Lin Wu*, Shu Wang*. Reversible Thermochromic Nanoparticles Composed of a Eutectic Mixture for Temperature-Controlled Photothermal Therapy. Nano Lett. 2020, DOI: 10.1021/acs.nanolett.0c00147.
[18] Song Shen, Chunlei Zhu, Da Huo, Miaoxin Yang, Jiajia Xue, Younan Xia*. A Hybrid Nanomaterial for the Controlled Generation of Free Radicals and Oxidative Destruction of Hypoxic Cancer Cells. Angew. Chem. Int. Ed. 2017, 56, 8801–8804.
[17] Song Shen*, Fei Han, Anran Yuan, Lin Wu*, Jin Cao, Jing Qian, Xueyong Qi, Yongsheng Yan, Yanru Ge*. Engineered nanoparticles disguised as macrophages for trapping lipopolysaccharide and preventing endotoxemia
Biomaterials, 2019, 189, 60-68.
[16] Song Shen, Marhaba Mamat, Shengchang Zhang, Jin Cao, Zachary D. Hood, Legna Figueroa-Cosme, and Younan Xia*. Synthesis of CaO₂ Nanocrystals and Their Spherical Aggregates with Uniform Sizes for Use as a Biodegradable Bacteriostatic Agent. Small 2019, **.
[15] Song Shen*, D. Huang, J. Cao, Y.Chen, X. Zhang, S. Guo, W. Ma, X. Qi, Y. Ge* and L. Wu*. Magnetic liposomes for light-sensitive drug delivery and combined photothermal–chemotherapy of tumors. J. Mater. Chem. B, 2019, 7, 1096
[14] Lin Wu, Song Shen*. What potential do magnetic iron oxide nanoparticles have for the treatment of rheumatoid arthritis? Nanomedicine, 2019, 14(8), 927–930.
[13] Lin Wu, Ling Zong, Haihua Ni, Xuexue Liu, Wen Wen, Lei Feng, Jin Cao*, Xueyong Qi, Yanru Ge*, and Song Shen*. Magnetic Thermosensitive Micelles with Upper Critical Solution Temperature for NIR Triggered Drug Release. Biomater. Sci. 2019, 7, 2134
[12] Song Shen, Bei Ding, Shengchang Zhang, Xueyong Qi*, Kun Wang, Jie Tian, Yongsheng Yan, Yanru Ge* and Lin Wu*. Near-Infrared Light-Responsive Nanoparticles with Thermosensitive Yolk-Shell Structure for Multimodal Imaging and Chemo-Photothermal Therapy of Tumor. Nanomed: Nanotech. Biol. Med., 2017, 13(5):1607-1616.
[11] Shen S, Kong FF, Guo XM, Wu L, Shen HJ, Xie M, Wang XS, Jin Yi*, Ge YR*. CMCTS stabilized Fe₃O₄ nanoparticles with extremely low toxicity as highly efficient near-infrared photothermal agents for in vivo tumor ablation. Nanoscale, 2013, 5, 8056–8066.
[10] Ling Chen, Lin Wu, Fei Liu, Xueyong Qi, Yanru Ge* and Song Shen*. Azo-functionalized Fe3O4 nanoparticles: a near-infrared light triggered drug delivery system for combined therapy of cancer with low toxicity. J. Mater. Chem. B, 2016, 4, 3660-3669.
[9] Lin Wu, Ling Chen, Fei Liu, Xueyong Qi, Yanru Ge, Song Shen*. Remotely controlled drug release based on iron oxide nanoparticles for specific therapy of cancer. Colloids Surf B Biointerfaces, 2017, 152: 440–448.
[8] Shengchang Zhang, Lin Wu, Jin Cao, Kaili Wang, Yanru Ge, Wanjun Ma, Xueyong Qi, Song Shen*. Effect of magnetic nanoparticles size on rheumatoid arthritis targeting and photothermal therapy. Colloids and Surfaces B: Biointerfaces, 170 (2018) 224–232.
[7] Song Shen, Lin Wu, Meng Xie, Haijun Shen, Xueyong Qi, Yongmin Yan, Yanru Ge and Yi Jin. Core-shell structured Fe₃O₄@TiO₂ nanoparticles for targeted chemo-sonodynamic therapy of cancer. Int. J. Pharm., 2015, 486, 380–388 (IF: 3.785).
[6] Song Shen, Xiaomeng Guo, Lin Wu, Meng Wang, Xinshi Wang, Fenfen Kong, Haijun Shen, Meng Xie, Yanru Ge, Yi Jin. Dual-core@shell-structured Fe₃O₄-NaYF₄@TiO₂ Nanocomposites as Magnetic Targeting Drug Carrier for Bioimaging and Combined Chemo-sonodynamic Therapy. J. Mater. Chem. B, 2014, 2, 5775. (IF: 4.8)
[5] MengJia Chen, Airen Xu, Wenyue He, Weicheng Ma*, Song Shen*. Ultrasound triggered drug delivery for mitochondria targeted sonodynamic therapy. J Drug Deliv Sci Tec, 2017, 39, 501–507.
[4] Bei Ding, Song Shen*, Lin Wu, Xueyong Qi, Haihua Ni, Yanru Ge. Doxorubicin loaded Fe₃O₄@SiO₂ nanoparticles as magnetic targeting agents for combined photothermal-chemotherapy of cancer. Chemistry letters, 2015, 6, 858-860 (IF: 1.4).
[3] Fei Liu, Lin Wu, Ling Chen, Xueyong Qi, Yanru Ge, and Song Shen. Ultrasound-guided Tumor Sonodynamic Therapy Based on Sonosensitizer Liposome. Chem. Lett. 2016, 45, 1304–1306.
[2] Song Shen, Bei Ding, Lin Wu, Xueyong Qi, Yanru, Ge. Fe₃O₄@TiO₂ nanocomposites for magnetic targeting sonodynamic therapy of cancer. Key Engineering Materials, 2015, 636: 129-132. (EI)
[1] Song Shen, Bei Ding, Qing Li, Xuwei Yu, Xueyong Qi, Yanru Ge. A novel chitosan microbubble as ultrasound-triggered drug carrier for antitumor in vitro. Key Engineering Materials, 2015, 636: 139-143. (EI)



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