[个人简介]
性别：男
出生日期：1985年8月
职称：副研究员, 硕士生导师
E-mail：mt3138@ujs.edu.cn
[教育经历]
2012-2016 东京大学 生物情报工学 博士
2009-2012 东华大学 生物化学与分子生物学 硕士
2005-2009 苏州科技大学 生物科学 本科
[工作经历]
2018-至今 江苏大学 副研究员
2018-2019 亚利桑那大学 助理研究员
2017-2018 伊坎西奈山医学院(纽约) 博士后
2016-2017 哥伦比亚大学(纽约) 博士后



[主讲课程]
生物信息学



[研究领域]
算法开发和数据挖掘
高通量测序数据的流程开发
[学术活动]
Disease Markers 青年编委
Frontiers 特邀编辑
https://www.frontiersin.org/research-topics/11080/computational-methods-in-inferring-cancer-tissue-of-origin-and-cancer-molecular-classification-volum
https://www.frontiersin.org/research-topics/14361/computational-tools-in-inferring-cancer-tissue-of-origin-and-molecular-classification-towards-person
https://www.frontiersin.org/research-topics/19690/computational-tools-in-inferring-cancer-tissue-of-origin-and-molecular-classification-towards-person
BioMed Research International 特邀编辑
https://www.hindawi.com/journals/bmri/si/712473

[科研项目]
江苏大学高级人才启动基金 主持， 在研
江苏省双创博士项目 主持， 在研
国家自然科学基金青年项目 主持， 在研
[主要论文]


[1] Tang M, Alaniz ME, Felsky D, Vardarajan B, Reyes-Dumeyer D, Lantigua R, Medrano M, Bennett DA, de Jager PL, Mayeux R, Santa-Maria I, Reitz C (2020). Synonymous variants associated with Alzheimer disease in multiplex families. Neurology Genetics, 6(4):e450.
[2] Tang M, Kui L, Lu GY, Chen WQ (2020). Disease-associated circular RNAs: from biology to computational identification. BioMed Research International, 2020: **.
[3] Li WB, Kui L, Demetrios T, Gong X, Tang M* (2020). A Glimmer of Hope:Maintain Mitochondrial Homeostasis to Mitigate Alzheimer's Disease. Aging and disease, 11(5):1260-1275.
[4] Tang M, Reitz C (2017). Genetics of Alzheimer's disease - an update. Future Neurology, 12:237-247.
[5] Tang M, Sun J, Shimizu K, Kadota K (2015). Evaluation of methods for differential expression analysis on multi-group RNA-seq count data. BMC Bioinformatics, 16:361.
[6] Yang X, Kui L, Tang M, Li D, Wei K, Chen W, Miao J, Dong Y (2020). High-Throughput Transcriptome Profiling in Drug and Biomarker Discovery. Frontiers in Genetics, 11.
[7] Wang N, Zhu F, Shen M, Qiu L, Tang M, Xia H, Chen L, Yuan Y, Ma S, Chen K (2019). Network pharmacology-based analysis on bioactive anti-diabetic compounds in Potentilla discolor bunge. J Ethnopharmacol, 241:111905.
[8] Lu M, Xu X, Xi B, Dai Q, Li C, Su L, Zhou X, Tang M, Yao Y, Yang J (2018). Molecular Network-Based Identification of Competing Endogenous RNAs in Thyroid Carcinoma. Genes (Basel), 9.
[9] Qureshi YH, Patel VM, Berman DE, Kothiya MJ, Neufeld JL, Vardarajan B, Tang M, Reyes-Dumeyer D, Lantigua R, Medrano M, Jime?nez-Vela?zquez IJ, Small SA, Reitz C (2018). An Alzheimer's disease-linked loss-of-function CLN5 variant impairs cathepsin D maturation, consistent with a retromer trafficking defect. Molecular and cellular biology, 38:e00011-00018.
[10] Ge Q, Zhang S, Chen L, Tang M, Liu L, Kang M, Gao L, Ma S, Yang Y, Lv P, Kong M, Yao Q, Feng F, Chen K (2018). Mulberry Leaf Regulates Differentially Expressed Genes in Diabetic Mice Liver Based on RNA-Seq Analysis. Front Physiol, 9:1051.
[11] Ge Q, Chen L, Tang M, Zhang S, Liu L, Gao L, Ma S, Kong M, Yao Q, Feng F, Chen K (2018). Analysis of mulberry leaf components in the treatment of diabetes using network pharmacology. Eur J Pharmacol, 833:50-62.
[12] Cheng R, Tang M, Martinez I, Ayodele T, Baez P, Reyes-Dumeyer D, Lantigua R, Medrano M, Jimenez-Velazquez I, Lee JH, Beecham GW, Reitz C (2018).
[13] Linkage analysis of multiplex Caribbean Hispanic families loaded for unexplained early-onset cases identifies novel Alzheimer's disease loci. Alzheimers Dement (Amst), 10:554-562.
[14] 汤敏, 倪丽菊, 高骏, 肖君华, 胡建华, 高诚. 东方田鼠部分BAC文库的微卫星筛选[J]. 中国实验动物学报, 2012, 20(3):50-55.


[主要论著]
[1] Chen WQ, Tang M* (2020). An introduction to single-cell RNA-seq analysis and its applications. Systems Medicine: Integrative, Qualitative and Computational Approaches, 1:116-128.
[2] Sun JQ, Tang M* (2020). The programming languages: introduction of R. Systems Medicine: Integrative, Qualitative and Computational Approaches, 1:1-8.
[3] Kui L, Tang M* (2020). Overview of Computational Methods and Resources for circular RNAs. Systems Medicine: Integrative, Qualitative and Computational Approaches,1:85-93.
[4]門田幸二, 孫建強, 湯敏, 西岡輔, 清水謙多郎,「次世代シーケンサーデータの解析手法：第1回イントロダクション」, 日本乳酸菌学会誌, 25(2):87-94, 2014.
[5] 孫建強, 湯敏, 西岡輔, 清水謙多郎, 門田幸二,「次世代シーケンサーデータの解析手法：第2回GUI環境からコマンドライン環境へ」, 日本乳酸菌学会誌, 25(3):166-174, 2014.
[6] 孫建強, 湯敏, 清水謙多郎, 門田幸二,「次世代シーケンサーデータの解析手法：第4回クオリティコントロールとプログラムのインストール」, 日本乳酸菌学会誌, 26(2):124-132, 2015.