张业旺副教授l联系方式：江苏镇江学府路301号江苏大学药学院2413室邮编：212013电话/传真：0511-85038201（办）Email：zhangyewangujs.edu.cnl教育经历2002.09-2006.03，华东理工大学，博士，生物化工1997.09-2000.06，大连理工大学，硕士，生物化工1993.09-1997.06，武汉化工学院，学士，有机化工l工作经历：2009.03-2010.08，Assistantprofessor，KonkukUniversity,韩国2009.07至今副教授，江苏大学2008.09-2009.02，Postdoc，KonkukUniversity,韩国2006.06-2009.07，讲师，江苏大学2000.06-2002.07，研发工程师，石家庄制药集团l研究方向：生物催化与转化，制药过程工程。主要包括：(1)重要药物中间体的生物法生产新技术开发；(2)重要生物催化剂的修饰和开发；(3)制药过程集成化技术。招收生药学学术型研究生与制药工程专业学位研究生。欢迎化学、微生物学、分子生物学与药学相关专业的考生报考。l研究项目：1.江苏大学高级人才基金(主持,07JDG034)。2.国家自然科学基金(参与,30771176)。3.江苏省高校自然基金，(主持，09KJB530001)。4.江苏省博士后项目(主持,1101038C)。5.江苏省大气污染与环境检测重点实验室开放课题(主持，kHK1109)。6.中国博士后科学基金(主持，2012M511696)。l学术兼职担任ProcessBiochemistry，EnzymeandMicrobialTechnology,SpectroscopyLetters,InstrumentationScienceandTechnology,AppliedMicrobiologyandBiotechnology,JournalofScientificandIndustrialResearch等国际期刊的审稿人。l已发表代表性论文（*通讯联系人）：1.YueLi,Xiang-YuWang,Rui-ZhuoZhang,Xiao-YunZhang,Xi-MingXu,Ye-WangZhang*.MolecularImprintingandImmobilizationofCellulaseontoMagneticFe₃O₄@SiO₂Nanoparticles.JournalofNanoscienceandNanotechnology.Accepted.2.WeiLiu,FangZhou,Xiao-YunZhang,YueLi,Xiang-YuWang,Xi-MingXu,Ye-WangZhang*.PreparationofmagneticFe₃O₄@SiO₂nanoparticlesforimmobilizationoflipase.JournalofNanoscienceandNanotechnology.Accepted.3.JianfengWang,WeiLiu,BaoquanLiu,ShengdiFan,Ye-WangZhang*.Analyzingincreasedfluorescenceofsinglequantumdotsondehydratedagarosebysingle-molecularimaging.SpectroscopyLetters.2013,46:195-200.4.Ye-WangZhang,ManishKumarTiwarri,HuiGao,MarimuthuJeya,Jung-kulLee*.CloningandcharacterizationofathermostableH₂O-formingNADHoxidasefromLactobacillusrhamnosus.EnzymeandMicrobialTechnology.2012,50:255-262.5.Ye-WangZhang,ManishKumarTiwarri,MarimuthuJeya,Jung-kulLee*.CovalentimmobilizationofrecombinantRhizobiumetliCFN42xylitoldehydrogenaseontomodifiedsilicananoparticles.AppliedMicrobiologyandBiotechnology.2011,90:499-507.6.Ye-WangZhang,MarimuthuJeya,Jung-KulLee*.EnhancedactivityandstabilityofL-arabinoseisomerasebyimmobilizationonaminopropylglass.AppliedMicrobiologyandBiotechnology.2011,89:1435-1442.7.RaushanKumarSingh,Ye-WangZhang,Ngoc-Phuong-ThaoNguyen,MarimuthuJeya,Jung-KulLee*.Covalentimmobilizationofβ-1,4-glucosidasefromAgaricusarvensisontofunctionalizedsiliconoxidenanoparticles.AppliedMicrobiologyandBiotechnology,2011,89:337-344.8.Ye-WangZhang*,Rui-JiangLiu,Xi-MingXu*.One-pot,two-stepenzymaticsynthesisofamoxicillinbycomplexingwithZn²⁺.AppliedMicrobiologyandBiotechnology,2010,88:49-55.9.Ye-WangZhang,MarimuthuJeya,Jung-KulLee*.L-RibuloseproductionbyanEscherichiacoliharboringL-arabinoseisomerasefromBacilluslicheniformis.AppliedMicrobiologyandBiotechnology,2010,87:1993-1999.10.Ye-WangZhang,PonnandyPrabhu,Jung-KulLee*.AlginateimmobilizationofrecombinantEscherichiacoliwholecellsharboringL-arabinoseisomeraseforL-ribuloseproduction.BioprocessandBiosystemsEngineering,2010,33:741-748.11.Ye-WangZhang,PonnandyPrabhu,Jung-KulLee,In-WonKim*.EnhancedstabilityofBacilluslicheniformisL-arabinoseisomerasebyimmobilizationwithalginate.PreparativeBiochemistryandBiotechnology,2010,40:65-75.12.QiangTan,YewangZhang,QingxunSong,DongzhiWei.Single-potconversionofcephalosporinCto7-aminocephalosporanicacidintheabsenceofhydrogenperoxide.WorldJournalofMicrobiologyandBiotechnology.2010,26:145-152.^13.Shu-GuangFang,TanQiang,Rui-JiangLiu,Xi-MingXu,Ye-WangZhang*.Enhancedproductionof6-aminopenicillanicacidinaqueous-methylisobutylketonesystemwithimmobilizedpenicillinGacylase.PreparativeBiochemistryandBiotechnology.2010,40(1):38-45.14.Ye-WangZhang,PonnandyPrabhu,Jung-kulLee*.ImmobilizationofBacilluslicheniformisL-arabinoseisomeraseforsemi-continuousL-ribuloseproduction.Bioscience,BiotechnologyandBiochemistry.2009,73:2234-2239.15.MarimuthuJeya,Ye-WangZhang,In-WonKim,Jung-KulLee*.EnhancedsaccharificationofalkalitreatedricestrawbycellulaseofTrameteshirsutaandstatisticaloptimizationofhydrolysisconditionbyRSM.BioresourceTechnology,2009,100(21):5155-5161.16.YewangZhang,DongzhiWei*.Enzymaticpreparationofcefaclorwithimmobilizedpenicillinacylase.PreparativeBiochemistryandBiotechnology.2008,38:136-145.17.YewangZhang,ShulaiLiu,DongzhiWei*,RuijiangLiu,XimingXu.Kineticallycontrolledsynthesisofcefaclorwithimmobilizedpenicillinacylaseinthepresenceoforganiccosolvents.ChemicalandBiochemicalEngineeringQuarterly.2008,22:349-354.18.DengchaoLi,YewangZhang,DongzhiWei*,QingxunSong,ShiweiCheng.Enzymaticsynthesiscephalexinathighsubstratesconcentrationwithinsituproductremoval.FoodTechnologyandBiotechnology.2008,46:461-466.19.RuiHan,YewangZhang,XiulingDong,HongweiGai*andEdwardS.Yeung.Spectralimagingofsinglemoleculesbytransmissiongratingbasedepi-fluorescencemicroscopy.AnalyticaChimicaActa.2008,619:209-214.20.Yewang.Zhang,DongzhiWei*,DengchaoLi,ShulaiLiu,QingxunSong.Optimisationofenzymaticsynthesisofcefaclorwithinsituproductremovalandcontinuousacyldonorfeeding.BiocatalysisandBiotransformation.2007,25:59-64.21.YewangZhang*,RuijiangLiu,XiaoyuWu.TheproteolyticsystemsandheterologousproteinsdegradationinthemethylotrophicyeastPichiapastoris.AnnalsofMicrobiology.2007,37,553-560.22.QiangTan,QingxunSong,YewangZhang,DongzhiWei*.CharacterizationandapplicationofD-aminoacidoxidaseandcatalasewithinpermeabilizedPichiapastoriscellsinbioconversions.AppliedBiochemistryandBiotechnology.2007,136:279-289.23.YewangZhang,DengchaoLi,QingxunSong,DongzhiWei*.Effectsofsubstrateconcentrationontheenzymaticsynthesisofcefaclorbypenicillinacylasewithinsituproductremoval.ChemicalandBiochemicalEngineeringQuarterly.2006,20:183-188.