江南大学药学院硕士研究生导师简介-陈敬华
江南大学 免费考研网/2013-12-21
<=spanlang=3DEN-USstyle=3D'font-size:9.0pt;color:#333333;mso-font-kerning:0pt'=><=spanstyle=3D'font-size:9.0pt;font-family:SimSun;mso-ascii-font-family:"Times=NewRoman";color:#333333;mso-font-kerning:0pt'>【个人简&201=71;】=姓名陈敬华，JinghuaChen=性别男=出生日期1971.08=职称教授=电话0510－85911900=传真0510－85911900=E-mailjhchenwhut@126.com<=spanlang=3DEN-USstyle=3D'font-size:9.0pt;color:#333333;mso-font-kerning:0pt'=><=spanstyle=3D'font-size:9.0pt;font-family:SimSun;mso-ascii-font-family:"Times=NewRoman";color:#333333;mso-font-kerning:0pt'>【学术简&201=71;】〖学&2=0064;经历〗：
1996-1997=日本&228=23;阪大学理学部高分子=科学系,联合培养&21338=;士生1994-1999武汉&228=23;学化学系高分子化学=与物理专业,博士1990-1994武汉&228=23;学化学系化学专业<=spanlang=3DEN-USstyle=3D'font-size:9.0pt;line-height:125%;mso-hansi-font-fam=ily:SimSun;color:black;mso-font-kerning:0pt'>,本科〖工&2=0316;经历〗：2008-至今江南大学&33647=;学院教授,博士生导&24072=;2006-2007美国&212=71;卡大学药学院,访问教授=2005-2008武汉&297=02;工大学化学工程学院=制药工程系,教授2001-2005美国&212=71;卡大学药学院,博士后研&31350=;员2000-2001=日本&228=23;阪大学蛋白质研究所=,客座研究&21592=;1999-2000=国家&200=13;药现代化工程技术研=究中心,工程师〖学术及&310=38;会兼职〗：
美国化学会会员，国&=38469;糖生物学会会员<=spanstyle=3D'font-size:9.0pt;font-family:SimSun;mso-ascii-font-family:"Times=NewRoman";color:#333333;mso-font-kerning:0pt'>【主讲课&312=43;】本科&299=83;：药剂学研究&299=83;：化学生物学、药用=高分子材料、生物医&3=3647;学科前沿导论<=spanstyle=3D'font-size:9.0pt;font-family:SimSun;mso-ascii-font-family:"Times=NewRoman";color:#333333;mso-font-kerning:0pt'>【指导硕&122=89;博士生研究方向】<=/b>专业方向：博士&299=83;：制药工程与技术，=发酵工程；硕士生：药学&6=5288;学术型）、制药工&3124=3;（专业型）、生物工&=#31243;（专业型）研究方向：生物活性高分&2=3376;、糖药物、Glycomaterials<=spanstyle=3D'font-size:9.0pt;font-family:SimSun;mso-ascii-font-family:"Times=NewRoman";color:#333333;mso-font-kerning:0pt'>【研究领&224=95;】（1）生物活&=#24615;大分子的制备、结&26=500;改造、构象及构效&20851=;系（2）糖药物和多糖基生物智&=#33021;药物传递系统<=spanstyle=3D'font-size:9.0pt;line-height:125%;font-family:SimSun;mso-ascii-fo=nt-family:"TimesNewRoman";mso-hansi-font-family:"TimesNewRoman";color:#333333;mso-font-kerning:0pt;mso-bidi-font-weight:bold'>（3）基于生物&279=63;性大分子的生物医学=材料<=spanstyle=3D'font-size:9.0pt;font-family:SimSun;mso-ascii-font-family:"Times=NewRoman";color:#333333;mso-font-kerning:0pt'>【主要论&338=79;】=1.&n=bsp;C.Deng,Z.Hu,H.Fu,M.Hu,X.Xu,J.Chen*,Chemicalanalysisandantioxidantactivityinvitroofaβ-D-glucanisolated=fromDictyophoraindusiata,InternationalJournalofBiologic=alMacromolecules,2012,51(1-2),70-75.=2.=Y.Liu,L.Liu,J.Chen,J.Li,G.Du,J.Chen,EffectsofcarbonsourcesandfeedingstrategiesonheparosanproductionbyEscherichiacoliK5,BioprocessandBiosystemsEnginee=ring,2012,35(7),1209-1218.=3.=G.Lu,L.Kai,P.Zhao,Z.Xu,C.Deng,H.Zheng,J.Hu=ang,J.Chen*,Anovelinsitu-formedhydrogelwounddressingbythephotocross-linkingofachitosanderivative,Woundrepairandregeneration,2010,18(1),70-9.==4.=X.Zhang,J.Huang,P.Chang,J.Li,Y.Chen,D.Wang,=J.Yu,J.Chen,Structureandpropertiesofpolysaccharidenanocrystal-dopedsupramolecularhydrogelsbasedonCyclodextrininclusion,Polymer,2010,51(19),4398-4407.=5.=P.Xu,G.Guo,J.Huang,S.Zhou,D.Wang,J.Yu,J.Chen,Alginate-basedferrofluidandmagneticmicrospherethereof,InternationalJournalofBiologic=alMacromolecules,2010,47(5),654-660.=6.=J.Wang,X.Xu,H.Zheng,J.Li,C.Deng,Z.Xu,J.Chen*,StructuralCharacterization,ChainConformation,andMorphology=ofaβ-(1=→=3)-D-GlucanIsolatedfromtheFruitingBodyofDictyophoraindusiata,JournalofAgriculturalandFoodChemistry,2009,57(13),5918-5924.=7.=K.Ling,F.Zheng,J.Li,R.Tang,J.Huang,Y.Xu,H.Zheng,J.Chen*,EffectsofsubstitutiondegreeofphotoreactivegrouponthepropertiesontheUV-fabricatedchitosanscaffold,=JournalofBiomedicalMaterialResearch(A),2008,87(1),52-61.=8.=J.Chen,J.Courtney,J.Liu,Usinganenzymaticcombinatorialapproachtoidentifyanticoagulantheparanstructures,ChemistryandBiol=ogy,2007,14,986-993.=9.=J.Chen,F.Y.Avci,E.M.=Munozet.al.,Enzymaticredesigningofbiologicallyactiveheparansulfate<=/b>,JournalofBiologicalChem=istry,2005,280,42817-25.=10.G.Xia,J.Che=n,V.Tiwari,W.Juet.al.,Heparansulfate3-O-sulfotransferaseisoform5generatesbothanantithrombin-IIIbindingsiteandanentryreceptorforherpessimplexvirus,type1,JournalofBiologic=alChemistry,=2002,277,37912-37919.=11.L.MMcDowell，B.A.Frazier，D.R.Studelska，K.Giljum，J.Chenet.al.,InhibitionoractivationofapertsyndromeFGFR2(S2=52W)signalingbyspecificglycosaminoglycans,JournalofBiologicalChemistry,2006,281,6924-6930.=12.A.Neigishi,J=.Chen,D.M.MacCarty,R.J.Samulskiet.al.,Analysisoftheinteractionbetw=eenadeno-associatedvirusandheparansulfateusingatomicforcemicroscopy<=/b>,Glycobiology,2004,14,969-977.=13.<=spanlang=3DEN-USstyle=3D'font-size:9.0pt;line-height:120%'>J.Chen,M.B.Duncan,K.carrick,R.M.Popeet.al.=,Biosynthesisof3-O-sulfotransferaseheparansulfate:uniquesubstratespecificityof3-O-sulfotransferaseisoform5,Glycobiology,2003,13,785-794.=14.J.ChenandJ.Liu,Characterizationofthestructureofantithrombin-bindingheparansulfategeneratedbyheparansulfate3-O-sulfotransferase5,BiochimBiophysActa,=2005,1725,190-200.<=o:p>=15.M.B.Duncan,J=Chen,J.P.Krise,J.Liu,Thebiosynthesisofanticoagulantheparansulfate=bytheheparansulfate3-O-sulfotransferaseisoform5,BiochimBiophysActa,2004,1671,34-43.<=/b>=16.V.Tiwari,C.Clement,M.B.Duncan,J.Chenet.al.,Arolefor3-O-sulfatedheparansulfatein=cellfusioninducedbyherpessimplexvirustype1,JournalofGeneralVirology,2004,85,805-809.<=spanstyle=3D'font-size:9.0pt;font-family:SimSun;mso-ascii-font-family:"Times=NewRoman";color:#333333;mso-font-kerning:0pt'>【在研国&234=78;级科研项目】新型生物医用&2=6448;料的研制,新世纪优&31168=;人才支持计划酶法选择性改&3=6896;肝素结构制备肝素&3489=3;生物及其抗凝血活性&=#30740;究，教育部博士点&22=522;金表面原位合成&3=1867;肝素以提高生物材&2600=9;血液相溶性研究，国&=#23478;自然科学基金蛋白质吸附行&2=0026;与血液相容行生物&3964=0;分子材料的制备，973前期专项&23376=;课题新型抗凝血硫&3=7240;乙酰肝素的生物合&2510=4;及生物活性，教育部&=#22238;国留学人员启动基&37=329;<=spanstyle=3D'font-size:9.0pt;font-family:SimSun;mso-ascii-font-family:"Times=NewRoman";color:#333333;mso-font-kerning:0pt'>【科研成&265=24;及奖励】<=spanstyle=3D'font-size:9.0pt;line-height:125%;font-family:SimSun;mso-ascii-fo=nt-family:"TimesNewRoman";mso-hansi-font-family:"TimesNewRoman";color:#333333;mso-font-kerning:0pt'>已获批中国专&2=1033;4项，获批&222=69;际专利2项，正在&300=03;请的国际专利1项，中国&199=87;利20余项。<=spanstyle=3D'font-size:9.0pt;font-family:SimSun;mso-ascii-font-family:"Times=NewRoman";color:#333333;mso-font-kerning:0pt'>【主要授&264=35;和公开专利】1、Enzymaticsynthesisofsulfatedpolysaccharides，国&3=8469;发明专利，WO2006124801。2、Purifiedandisolatedheparinsulfate3-O-sulfotransferaseisoform5nucleicacidsandtherapeuticandscreeningmethodsusingSAMEisoform5nucleicacids=andtherapeuticandscreeningmethodsusingSAME，国&3=8469;发明专利，WO2004005475。3、一种制备肝素修饰=的金纳米粒子的方法&6=5292;发明专利公开号，200910024843.44、一种光交联壳聚糖=水凝胶膜的制备方法&6=5292;，发明专利公开号&6529=2;200910024842.X。5、一种制备高活性低=毒副作用肝素的方法&6=5292;发明专利公开号，201210464124.6。6、一种具有抗肿瘤活=性的低抗凝肝素的制&2=2791;方法，发明专利公&2432=0;号，201210464468.7。<=spanstyle=3D'font-size:9.0pt;font-family:SimSun;mso-ascii-font-family:"Times=NewRoman";color:#333333;mso-font-kerning:0pt'>【在读硕&122=89;博士人数】在读博士4人，硕士20人。<=spanstyle=3D'font-size:9.0pt;font-family:SimSun;mso-ascii-font-family:"Times=NewRoman";color:#333333;mso-font-kerning:0pt'>【已毕业&308=05;、博士人数】已毕业硕&227=63;15人。<=spanstyle=3D'font-size:9.0pt;font-family:SimSun;mso-ascii-font-family:"Times=NewRoman";color:#333333;mso-font-kerning:0pt'>【指导本&311=85;生人数】每年4-5人左右。<=spanstyle=3D'font-size:9.0pt;font-family:SimSun;mso-ascii-font-family:"Times=NewRoman";color:#333333;mso-font-kerning:0pt'>【以上资&260=09;更新日期】
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