博士研究生导师简介
姓名
吕镗烽
研究方向：
胸部肿瘤学，急性肺损伤及ARDS，肺部重症感染


联系方式
手机：**
E-mail：bairoushui@163.com

学术兼职：
任中华医学会慢阻肺联盟委员，中华医学会呼吸分会肺癌学组委员，江苏省医学会和江苏省医师协会呼吸分会委员， CSCO临床数据专业委员会委员，中国肺癌防治联盟预防委员会委员，中国肺癌防治联盟青年委员会委员，江苏研究型医院学会肺结节与肺癌MDT专委会常委，江苏省康复医学会呼吸康复委员会委员，江苏省医学会呼吸分会肺癌学组秘书，肿瘤学年鉴（中文版）秘书，《Translational Lung Cancer Research》杂志副主编。

个人简介

南京大学医学院附属金陵医院呼吸与危重症医学科副主任，副主任医师，南京大学博士生导师，南京医科大学和南方医科大学硕士生导师，美国德州理工大学访问****，《Translational Lung Cancer Research》杂志副主编。
主持和承担国家自然科学基金、江苏省自然科学基金和江苏省社会发展项目等多项研究课题，可支配经费500余万元。以第一作者和通讯作者发表研究论文近百篇，其中SCI论文50余篇，主编主译专著2本。获得省部级科技奖励2次。

代表性论文[近5年通讯作者和第一作者]

序号
论文名称
刊物名称及ISSN号
发表年份-卷-期-页
本人
排名

1
WNT5B exerts oncogenic effects and is negatively regulated by miR-5587-3p in lung adenocarcinoma progression.
Oncogene.
2020 39(7):1484-1497
共同通讯

2
LncRNA GMDS-AS1 inhibits lung adenocarcinoma development by regulating miR-96-5p/CYLD signaling.
Cancer Med.
2020 9(3):1196-1208
共同通讯

3
Geranylgeranyl diphosphate synthase 1 knockout ameliorates ventilator-induced lung injury via regulation of TLR2/4-AP-1 signaling.
Free Radic Biol Med.
2020 147():159-166
共同通讯

4
The Diagnostic Yield of Closed Needle Pleural Biopsy in Exudative Pleural Effusion: A Retrospective 10-year Study.
Ann Transl Med
2020 Apr;8(7):491.
通讯作者

5
Treatment with convalescent plasma for COVID-19 patients in Wuhan, China.
Med Virol.
2020 Apr 15:10.1002/jmv.25882. Online ahead of print.
通讯作者

6
Encephalitis as a clinical manifestation of COVID-19.
Brain Behav Immun.
2020 Apr 10:S0889-1591(20)30465-7. Online ahead of print.
通讯作者

7
Prolonged SARS-CoV-2 RNA shedding: Not a rare phenomenon.
Med Virol.
2020 Apr 29:10.1002/jmv.25952. Online ahead of print.
通讯作者

8
Zebrafish Xenograft Model of Human Lung Cancer for Evaluating Osimertinib Resistance.
Biomed Res Int.
2314-6133
2019():**
共同通讯

9
Treatment of uncommon mutations in non-small cell lung cancer: new evidence and treatment.
Transl Lung Cancer Res.
2218-6751
2019,8(3):302-316
共同通讯

10
Efficacy of rapid on-site evaluation for diagnosing pulmonarylesions and mediastinal lymph nodes: a systematic review andmeta-analysis
Transl Lung Cancer Res.
2218-6751
2019,8(6):1029-1044
通讯作者

11
Downregulation of GSDMD attenuates tumor proliferation via the intrinsic mitochondrial apoptotic pathway and inhibition of EGFR/Akt signaling and predicts a good prognosis in nonsmall cell lung cancer.
Oncol Rep.
1021-335X
2018,40(4):1971-1984.
共同通讯

12
Expression profiles and clinical value of plasma exosomal Tim-3 and Galectin-9 in non-small cell lung cancer.
Biochem Biophys Res Commun.
0006-291X
2018,498(3):409-415.
共同通讯

13
The correlation between crizotinib efficacy and molecular heterogeneity by next-generation sequencing in non-small cell lung cancer.
J Thorac Dis.
2072-1439
2018,10(5):2948-2959.
第一作者

14
RNA sequencing enables systematic identification of platelet transcriptomic alterations in NSCLC patients.
Biomedicine & Pharmacotherapy.
0753-3322
2018,105 (2018) 204–214.
共同通讯

15
TEAD4 exerts pro-metastatic effects and is negatively regulated by miR6839-3p in lung adenocarcinoma progression.
J Cell Mol Med.
1582-4934
2018,22(7):3560-3571.
共同通讯

16
Comparison of clinical and radiological characteristics between anaplastic lymphoma kinase rearrangement and epidermal growth factor receptor mutation in treatment na?ve advanced lung adenocarcinoma
J Thorac Dis
2072-1439
2017,9(10):3927-3937
共同通讯

17
Patterns and functional implications of platelets upon tumor "education"
Int J Biochem Cell Biol
1357-2725
2017,90:68-80
共同通讯

18
Erlotinib-based doublet targeted therapy versus erlotinib alone in previously treated advanced non-small-cell lung cancer: a meta-analysis from 24 randomized controlled trials
Oncotarget
1949-2553
2017,8(42):73258-73270
共同通讯

19
Protein regulator of cytokinesis-1 expression: prognostic value in lung squamous cell carcinoma patients
J Thorac Dis
2072-1439
2017,9(7):2054-2060
共同通讯

20
PRC1 contributes to tumorigenesis of lung adenocarcinoma in association with the Wnt/β-catenin signaling pathway
Mol Cancer
1476-4598
2017,16(1):108
共同通讯

21
NCAPG2 promotes tumour proliferation by regulating G2/M phase and associates with poor prognosis in lung adenocarcinoma
J Cell Mol Med
1582-4934
2017,21(4):665-676
共同通讯

22
Long intergenic noncoding RNA 00673 promotes non-small-cell lung cancer metastasis by binding with EZH2 and causing epigenetic silencing of HOXA5
Oncotarget
1949-2553
2017,8(20):32696-32705
共同通讯

23
Detection of oncogenic mutations in resected bronchial margins by next-generation sequencing indicates early relapse in stage IA lung adenocarcinoma patients
Oncotarget
1949-2553
2017,8(25):40643-40653
共同一作

24
Long non-coding RNA 00312 regulated by HOXA5 inhibits tumour proliferation and promotes apoptosis in Non-small cell lung cancer
J Cell Mol Med
1582-4934
2017,21(9):2184-2198
共同一作

25
Pulmonary ground-glass opacity: computed tomography features, histopathology and molecular pathology.
Transl Lung Cancer Res.
2218-6751
2017,6(1):68-75.
共同通讯

26
Correlation in histological subtypes with high resolution computed tomography signatures of early stage lung adenocarcinoma.
Transl Lung Cancer Res.
2218-6751
2017,6(1):14-22.
共同通讯

27
Transthoracic needle aspiration in solitary pulmonary nodule.
Transl Lung Cancer Res.
2218-6751
2017,6(1):76-85.
共同通讯

28
How to diagnose pulmonary nodules: from screening to therapy.
Transl Lung Cancer Res.
2218-6751
2017,6(1):3-5.
共同通讯

29
The pulmonary nodule ""discovered"" by pneumonia: a case rep
Transl Lung Cancer Res.
2218-6751
2017,6(1):92-96.
共同通讯

30
Comparison between endobronchial ultrasound-guided transbronchial biopsy and CT-guided transthoracic lung biopsy for the diagnosis of peripheral lung cancer: a systematic review and meta-analysis.
Transl Lung Cancer Res.
2218-6751
2017,6(1):23-34.
共同通讯

31
The imaging of small pulmonary nodules.
Transl Lung Cancer Res. Transl Lung Cancer Res.
2218-6751
2017,6(1):62-67.
共同通讯

32
Circulating long noncoding RNA GAS5 is a novel biomarker for the diagnosis of non-small cell lung cancer
Medicine (Baltimore)
0025-7974
2016,95(37):e4608
共同一作

33
Upregulation of long intergenic noncoding RNA 00673 promotes tumor proliferation via LSD1 interaction and repression of NCALD in non-small-cell lung cancer
Oncotarget
1949-2553
2016,7(18):25558-75
共同通讯

34
The role of TWIST1 in epithelial-mesenchymal transition and cancers
Tumour Biol
1010-4283
2016,37(1):185-97
通讯作者

35
Twist1-mediated 4E-BP1 regulation through mTOR in non-small cell lung cancer
Oncotarget
1949-2553
2015,6(32):33006-18
共同一作



承担科研项目[项目负责人]

序号
项目名称
项目来源
项目起讫
时间
项目负责人
入账经费（万元）

1
CRISPR/Cas9调节的 PD-1体外敲除联合MUC1、PSCA CAR-T技术治疗晚期非
江苏省科技厅社会发展--面上项目（BE**）
2019.07-
2022.06
吕镗烽
100

2
血小板外泌体来源的长非编码RNA Linc01021调控肺腺癌转移的机制研究
国家自然科学基金--面上项目
（**）
2018.01-
2021.12
吕镗烽
53

3
非编码RNA（ncRNA）在非小细胞肺癌早期诊断和预后中的研究
南京市国际联合研发项目
（）
2017.07-
2020.06
吕镗烽
5

4
高表达的linc01021在女性肺腺癌发生发展中作用的研究
江苏省自然科学基金（BK**）
2016.07-2019.07
吕镗烽
10

5
基于多组学技术支撑zPDX模型的晚期非小细胞肺癌精准诊疗新平台的建立及推广应用
江苏省科技厅
社会发展--重点项目-临床前沿技术（BE**）
2019.07-
2022.06
吕镗烽（第二负责人）
400



获奖情况

获奖成果名称
获奖类型与等级
评奖单位
获奖
时间
本人排名

非小细胞肺癌精准诊治转化研究及临床应用
科技进步二等奖
教育部
2016
2