Address:School of Chemistry and Chemical Engineering Nanjing University 22 Hankou Road, Nanjing, P. R. China

 

Phone: 86-25-83593072

 

Fax: 86-25-83685976

 

E-mail: njuzy@nju.edu.cn

 

 

 

 

 

 

 

Education and Research Experience:

 

1993-1997      B.S. Jilin University

 

1997-2002      Ph.D. Nanjing University

 

2002-2004      Postdoc in HongKong University of Science and Technology

 

2004-2006      Postdoc in Stanford University, Molecular Imaging Programm of Stanford

 

2006-present   Professor of chemistry in Nanjing University

 

 

 

Current research interests:

 

The main research interest in Yan Zhang’s group is to use photoactive molecules and photochemistry to construct small molecular probes or nano-probes for chemical biological study and optical imaging.

 

 

 

Selected Publications:

1.Heng Jiang, Chengmei Huang, Jiajia Guo, Chuanqi Zeng, Yan Zhang,* and Shouyun Yu*, Direct C-H Functionalization of Enamides and Enecarbamates by Using Visible-Light Photoredox Catalysis, Chem. Eur. J., 2012, 18, 15158-15166.

2.Xuejiao Chen, Chengmei Huang, Wenjie Zhang, Yihan Wu, Xi Chen*, Chen-yu Zhang* and Yan Zhang*, Universal activator of microRNAs identified from photoreaction products, Chem. Commun., 2012, 48, 6432–6434.

3.Dongdong Wu, Lei Wang, Kai Xu, Jia Song, Hoong-Kun Fun, Jianhua Xu and Yan Zhang*，Facile and highly atom-economic approach to biaryl-containing medium-ring bislactones.Chem. Commun., 2012, 48, 1168 – 1170.

4.Jinbo Li, Subee Tan, Xuejiao Chen, Chen-yu Zhang and Yan Zhang*， Peptide aptamers with biological and therapeutic applications. Curr. Med. Chem., 2011, 18, 4215-4222.

5.Lei Wang, Yu-Cheng Huang, Yang Liu, Hoong-Kun Fun, Yan Zhang*, Jian-Hua Xu*. Photoinduced [4+4], [4+2] and [2+2] cycloadditions of o-quinones with oxazoles — chemo-, regio- and diastereoselectivity. J. Org. Chem. 2010, 75, 7757-7761.

6.Haitao Yu, Jinbo Li, Zhuangfei Kou, Xuewen Du, Yi Wei, Hoong-Kun Fun, Jianhua Xu and Yan Zhang*， Photoinduced Tandem Reactions of Isoquinoline-1,3,4-trione with Alkynes To Build Aza-polycycles， J. Org. Chem. 2010, 75, 2989-2992.

7.Haitao Yu, Jinbo Li, Dongdong Wu, Zhenjun Qiu and Yan Zhang*, Chemistry and biological applications of photo-labile organic molecules Chem. Soc. Rev., 2010, 39, 464-469.

8.Manlung Ma, Yi Kuang, Yuan Gao, Yan Zhang, Ping Gao, and Bing Xu*, Aromatic-Aromatic Interactions Induce the Self-Assembly of Pentapeptidic Derivatives in Water To Form Nanofibers and Supramolecular Hydrogels, J. Am. Chem. Soc., 2010, 132, 1719-1728.

9.Zhenjun Qiu, Haitao Yu, Jinbo Li, Yu Wang and Yan Zhang*, Spiropyran-linked dipeptide forms supramolecular hydrogel with dual responses to light and to ligand–receptor interaction Chem. Commun., 2009, 3342-3346.

10.Hequan Yao, Yan Zhang, Fei Xiao, Zuyong Xia, Jianghong Rao*, Quantum Dot/Bioluminescence Resonance Energy Transfer Based Highly Sensitive Detection of Proteases Angew. Chem. Int. Ed.， 2007, 46， 4346-4350

11.Yan Zhang, Min-kyung So and Jianghong Rao*, Protease-Modulated Cellular Uptake of Quantum Dots Nano Lett. 2006， 6，1988-1993.

12.Yan Zhang, Min-kyung So, Andreas M. Loening, Hequan Yao, Sanjiv S. Gambhir, and Jianghong Rao*, HaloTag Protein-Mediated Specific Conjugation of Bioluminescent Proteins to Quantum Dots Angew. Chem. Int. Ed.， 2006， 45， 4936-4940

13.Yan Zhang, Zhimou Yang, Fang Yuan, Hongwei Gu, Ping Gao and Bing Xu*, Molecular Recognition Remolds the Self-Assembly of Hydrogelators and Increases the Elasticity of the Hydrogel by 106-Fold J. Am. Chem. Soc., 2004, 126, 15028-15032

14.Yan Zhang, Lei Wang, Min Zhang, Hoong Kun Fun and Jian-Hua Xu*, Photoinduced [4 + 4] Cycloadditions of o-Quinones with Oxazoles Org. Lett., 2004, 6, 4893-4899

15.Yan Zhang, Hongwei Gu, Zhimou Yang and Bing Xu*, Supramolecular Hydrogels Respond to Ligand-Receptor Interaction J. Am. Chem. Soc., 2003, 125, 13680-13685