个人简介
邱吉国，博士，副研究员，生命科学学院微生物系。
研究方向：环境微生物学、微生物生理学等。
招生：硕士研究生导师。欢迎致力于微生物学研究、勤奋努力、具有团队合作精神的学生报考！
General information
Name: Jiguo Qiu
Affiliation: Key Laboratory of Agricultural Environmental Microbiology of Ministry of Agriculture, College of Life Sciences, Nanjing Agricultural University, NO.1 Weigang, Nanjing 210095, Jiangsu Province, P. R. China
Tel: (86)-
Fax: (86)-
Email: qiujiguo@njau.edu.cn
qiujiguo456@gmail.com
Personal schoolar website:
https://www.researchgate.net/profile/Jiguo_Qiu
https://scholar.google.com/citations?hl=zh-CN&user=KTOLjJ0AAAAJ&view_op=list_works&sortby=pubdate
Education and Employment History
01/2019-present Associate Prof.in Microbiology, College of Life Sciences, Nanjing Agricultural University, China.
07/2019-08/2020Visiting Scholarin Microbiology, School of Medicine, University of Washington, Seattle, USA.
04/2016-12/2018Assistant Prof.in Microbiology, College of Life Sciences, Nanjing Agricultural University, China.
04/2014-04/2016Postdocin Environmental Science and Technology, College of Environment, Zhejiang University of Technology, China.
09/2010-03/2014Ph.D.in Environmental Science, College of Environmental and Resource Sciences, Zhejiang University, China.
09/2006-06/2009M.S.in Microbiology, College of Life Sciences, Nanjing Agricultural University, China.
09/2001-06/2005B.S.in Sericulture, School of Forestry, Shandong Agricultural University, China
Research Projects
PrincipalInvestigator. The catabolism of phenazine-1-carboxylic acid by bacterial strain Rhodococcus sp. WH99. National Natural Science Foundation of China (No. **). 01/2021-12/2024
PrincipalInvestigator. The catabolism of cotinine in Nocardioides sp. strain JQ2195. National Natural Science Foundation of China (No. **). 01/2019-12/2022
Principal Investigator. Molecular mechanism study on nicotine metabolism by Pusillimonas sp. T2. National Natural Science Foundation of China (No. **). 01/2016-12/2018
PrincipalInvestigator. Characterization and structure analyse of the tetrahydrofolate (THF)-dependent dicamba demethylase. China Postdoctoral Science Foundation (No. 2016M601826). 042016-04/2018
Research experience
My research has involved in the biodegradation of toxic compoundsby bacteria: (1) isolates and characterizes novel degrading strains; (2) determines the degrading pathways of compounds; (3) clones novel degradation genes or enzymes using ‘transposon mutagenesis’ and chromosome walking; (4) clones, overexpresses, and purifies the functional enzymes; (5) constructs recombinant for biocatalysis,bioremediation and synthetic biology.
Methods used: (1) Isolation and purification of DNA, RNA, plasmids from environmental samples. (2) High throughput sequencing (phylogenetic and functional marker genes). (3) Quantitative PCR. (4) Phylogenetic analysis, probe and primer design. (5) Cultivation and selecttion of bacteria and mutants. (6) Gene transfer including conjugation, transduction, classical transformation and electroporation, monitoring of gene transfer events. (7) Gene knockout and complementation. (8) Multivariate statistics. (9) Laboratory-based microbial model systems. (10) Bioinformatics and genomics. (11) Software on biological analysis, such as bioedit, omiga, mega, DNAman.
Publication list (*Corresponding author)
[1] Rabia Najme, Shulin Zhuang, Jiguo Qiu*, Zhenmei Lu*. Identification and characterization of nornicotine degrading strain Arthrobacter sp. NOR5. Science of the Total Environment, 2021, 764 (4): 142894.
[2] Siqiong Xu, Junwei Liu, Haiyan Ni, Xiaojun Yang, Jiguo Qiu*, Xing Huang, Jian He. Rudanella paleaurantiibacter sp. nov., isolated from activated sludge. Current Microbiology, 2020, 77 (9–10): 2016-2022.
[3] Yang Mu, Qing Chen, Rebecca E. Parales, Zhenmei Lu, Qing Hong, Jian He, Jiguo Qiu*, Jiandong Jiang*. Bacterial catabolism of nicotine: Catabolic strains, pathways and modules. Environmental Research, 2020, 183 (4): 109258.
[4] Shijun Zhu, Hui Wang, Wankui Jiang, Zhangong Yang, Yidong Zhou, Jian He, Jiguo Qiu*, Qing Hong. Genome analysis of carbaryl-degrading strain Pseudomonas putida XWY-1. Current Microbiology, 2019, 76 (8): 927-929.
[5] Yanting Zhang, Junbin Ji, Siqiong Xu, Hongmei Wang, Biao Shen, Jian He, Jiguo Qiu*, Qing Chen*. Biodegradation of picolinic acid by Rhodococcus sp. PA18. Applied Sciences, 2019, 9 (5): 1006.
[6] Jiguo Qiu, Lingling Zhao, Siqiong Xu, Qing Chen, Le Chen, Bin Liu, Qing Hong, Zhenmei Lu, Jian He*. Identification and characterization of a novel pic gene cluster responsible for picolinic acid degradation in Alcaligenes faecalis JQ135. Journal of Bacteriology, 2019, 201 (16): e00077-00019.
[7] Jiguo Qiu, Yanting Zhang, Shigang Yao, Hao Ren, Meng Qian, Qing Hong, Zhenmei Lu*, Jian He*. Novel 3, 6-dihydroxypicolinic acid decarboxylase mediated picolinic acid catabolism in Alcaligenes faecalis JQ135. Journal of Bacteriology, 2019, 201 (7): e00665-00618.
[8] Jiguo Qiu, Yanting Zhang, Lingling Zhao, Qin He, Jian-Dong Jiang, Qing Hong, Jian He*. Isolation and characterization of the cotinine-degrading bacterium Nocardioides sp. strain JQ2195. Journal of Hazardous Materials, 2018, (353): 158-165.
[9] Jiguo Qiu, Bin Liu, Lingling Zhao, Yanting Zhang, Dan Cheng, Xin Yan, Jiandong Jiang, Qing Hong, Jian He*. A novel degradation mechanism for pyridine derivatives in Alcaligenes faecalis JQ135. Applied and Environmental Microbiology, 2018, 84 (15): e00910-00918.
[10] Yanting Zhang, Qing Chen, Junbin Ji, Lingling Zhao, Lei Zhang, Jiguo Qiu*, Jian He. Complete genome sequence of Alcaligenes faecalis strain JQ135, a bacterium capable of efficiently degrading nicotinic acid. Current Microbiology, 2018, 75 (12): 1551-1554.
[11] Minggen Cheng, Yi Li, Yan Ma, Jiguo Qiu*, Xin Yan, Jian He. Complete genome sequence of Sphingobium baderi DE-13, an alkyl-substituted aniline-mineralizing bacterium. Current Microbiology, 2018, 75 (1): 27-31.
[12] Qing Chen, Hongmei Wang, Wen Zhuang, Zhongguan Sun, Jing Chen, Yan Ge, Jiguo Qiu*, Jian He. Flavobacterium zaozhuangense sp. nov., a new member of the family Flavobacteriaceae , isolated from metolachlor-contaminated soil. Antonie Van Leeuwenhoek, 2018, 111 (11): 1977-1984.
[13] Mei Yuan, Yanting Zhang, Lingling Zhao, Yun Ma*, Qin He, Jian He, Jiguo Qiu*. Identification and characterization of a new three‐component nicotinic acid hydroxylase NahAB1B2 from Pusillimonas sp. strain T2. Letters in Applied Microbiology, 2018, (66): 321-328.
[14] Shijun Zhu, Jiguo Qiu, Hui Wang, Xiang Wang, Wen Jin, Yingkun Zhang, Chenfei Zhang, Gang Hu, Jian He, Qing Hong*. Cloning and expression of the carbaryl hydrolase gene mcbA and the identification of a key amino acid necessary for carbaryl hydrolysis. Journal of Hazardous Materials, 2018, (344): 1126-1135.
[15] Jiguo Qiu, Junjie Zhang, Yanting Zhang, Yuhong Wang, Lu Tong, Qing Hong, Jian He*. Biodegradation of picolinic acid by a newly isolated bacterium Alcaligenes faecalis strain JQ135. Current Microbiology, 2017, 74 (4): 508-514.
[16] Chenghong Wang, Jiguo Qiu#, Youjian Yang, Jinwei Zheng, Jian He*, Shunpeng Li. Identification and characterization of a novel carboxylesterase (FpbH) that hydrolyzes aryloxyphenoxypropionate herbicides. Biotechnology Letters, 2017, 39 (4): 553-560.
[17] Aiwen Li#, Jiguo Qiu#, Dongzhi Chen, Jiexu Ye, Yuhong Wang, Lu Tong, Jiandong Jiang*, Jianmeng Chen*. Characterization and genome analysis of a nicotine and nicotinic acid-degrading strain Pseudomonas putida JQ581 isolated from marine. Marine Drugs, 2017, 15 (6): 156.
[18] Jiguo Qiu, Youjian Yang, Junjie Zhang, Haixia Wang, Yun Ma, Jian He, Zhenmei Lu*. The complete genome sequence of the nicotine-degrading bacterium Shinella sp. HZN7. Frontiers in Microbiology, 2016, 7 (1348): 1-4.
[19] Jiguo Qiu, Na Li, Zhenmei Lu, Youjian Yang, Yun Ma, Lili Niu, Jian He, Weiping Liu*. Conversion of nornicotine to 6-hydroxy-nornicotine and 6-hydroxy-myosmine by Shinella sp. strain HZN7. Applied Microbiology and Biotechnology, 2016, 100 (23): 10019-10029.
[20] Jiguo Qiu, Meng Liu, Rongti Wen, Dou Zhang, Jun Hong. Regulators essential for nicotine degradation in Shinella sp. HZN7. Process Biochemistry, 2015, 50 (11): 1947-1950.
[21] Yun Ma, Rongti Wen, Jiguo Qiu*, Jun Hong, Meng Liu, Dou Zhang. Biodegradation of nicotine by a novel strain Pusillimonas. Research in Microbiology, 2015, 166 (2): 67-71.
[22] Jiguo Qiu, Yin Wei, Yun Ma, Rongti Wen, Yuezhong Wen, Weiping Liu*. A novel (S)-6-hydroxynicotine oxidase gene from Shinella sp. strain HZN7. Applied and Environmental Microbiology, 2014, 80 (18): 5552-5560.
[23] Jiguo Qiu, Yun Ma, Jing Zhang, Yuezhong Wen, Weiping Liu*. Cloning of a novel nicotine oxidase gene from Pseudomonas sp. strain HZN6 whose product nonenantioselectively degrades nicotine to pseudooxynicotine. Applied and Environmental Microbiology, 2013, 79 (7): 2164-2171.
[24] Jiguo Qiu, Yun Ma, Yuezhong Wen, Liansheng Chen, Lifei Wu, Weiping Liu*. Functional identification of two novel genes from Pseudomonas sp. strain HZN6 involved in the catabolism of nicotine. Applied and Environmental Microbiology, 2012, 78 (7): 2154-2160.
[25] Jiguo Qiu, Yun Ma, Liansheng Chen, Lifei Wu, Yuezhong Wen, Weiping Liu*. A sirA-like gene, sirA2, is essential for 3-succinoyl-pyridine metabolism in the newly isolated nicotine-degrading Pseudomonas sp. HZN6 strain. Applied Microbiology and Biotechnology, 2011, 92 (5): 1023-1032.
Last updated at Feb. 18, 2021

---

教学情况
-

---

科研情况
-

---