张文利联系方式:Tel:025-84396610;Email: wzhang25@njau.edu.cn个人简介:2005年,中国科学院遗传与发育生物学研究所,博士。2006.4-2008.12,美国威斯康辛大学-麦迪逊分校园艺系(Horticulture Department,University of Wisconsin-Madison),博士后。2009.1-2012.11,美国威斯康辛大学-麦迪逊分校园艺系,Associate Scientist。2012年12月,南京农业大学农学院作物遗传与种质创新国家重点实验室,教授,博士生导师。2014年,美国威斯康辛大学-麦迪逊分校园艺系,“Honorary Associate/Fellow”。2013年,美国威斯康辛大学农业与生命科学学院2012-2013年度“杰出研究人员奖”(Academic Staff Excellence in Research Awards)。2014年,江苏省双创人才。主要研究方向:植物表观调控基因组学1.植物R-loop、G4和i-Motif等non-B DNA生物学2.作物氮高效利用的表观分子基础。3. 作物纳米表观基因组学代表性论文:1.Tao ST, Lin KD, Zhu QQ, Zhang WL*(*通讯). 2020. MH-seq for functional characterization of open chromatin in plants. Trends Plant Sci.,25:618-619.2.Zhao HN#,Zhang WL#*(#共同第一,*共同通讯),Zhang T#,Lin Y,Hu YD,Fang C,Jiang JM*.2020.Genome-wide MNase hypersensitivity assay unveils distinct classes of open chromatin associated with H3K27me3 and DNA methylation in Arabidopsis thaliana, Genome Biol.,21:24.
3.Zhang PY#, Feng YL#(#共同第一), Wei HY*, Zhang WL* *共同通讯). 2019. R-loop identification and profiling in plants. Trends Plant Sci., 24: 971-972.4.Li ZJ#, Wang MY#, Lin KD#, Xie YL#(#共同第一), Guo JY, Ye LH, Zhuang YL, Teng W, Ran XJ, Tong YP, Xue YB, Zhang WL* (*共同通讯), Zhang YJ*. 2019. The bread wheat epigenome map reveals distinctchromatin architectural and evolutionary features of functional genetic elements. Genome Biol., 20: 139.5.Fang Y#, Chen LF#(#共同第一), Lin KD, Feng YL, Zhang PY, Pan XC, Sanders J, Wu YF, Wang XE, Su Z, Chen CY, Wei HY*, Zhang WL* (*共同通讯). 2019. Characterization of functional relationships of R-loops with gene transcription and epigenetic modification in rice. Genome Res., 29: 1287-1297.6.Zheng DY#, Wang L#, Chen LY#, Pan XC#(#共同第一), Lin KD, Fang Y, Wang XE, Zhang WL* (通讯). 2019. Salt-response genesare differentially regulated at the chromatin levels between seedlings and roots in rice. Plant Cell Physiol., 60: 1790-1803.7.Chen LF#,Wang XM#, Wang L#(#共同第一), Fang Y, Pan XC, Gao XQ, Zhang WL* (通讯). 2019. Functional characterization of chloroplast transit peptide in the small subunit of Rubisco in maize. J. Plant Physiol., 237: 12-20.8.Zhao HN*, Zhang WL*,¶(*共同第一;¶共同通讯), Chen LF, Wang L, Marand AP, Wu YF, and Jiang JM*,¶. 2018. Genome-wide mapping of open chromatin revealed proliferation of regulatory DNA elements derived from transposable elements in maize genome. Plant Physiol 176:2789-28039.Pan XC#, Fang Y#(co-first author),Yang XM, Zheng DY, Chen LF,WangL, Xiao J, Wang XE, Wang K, Cheng, ZK, Yu HX, and Zhang WL(通讯). 2017. Chromatin states responsible for the regulation of differentially expressed genes under 60Co~γ ray radiation in rice. BMC Genomics 18:77810.Liu Y#, Zhang WL#(共同第一), Zhang K, Yiu Q, Yan HY, Jiao YN, Jiang JM, Xu WY, Su Z. 2017. Genome-wide mapping of DNase I hypersensitive sites reveals chromatin accessibility changes in Arabidopsis euchromatin and heterochromatin in regions under extended darkness. SciRep7:409311.Zhang K, Xu WY, Wang CC, Yi X, Zhang WL#(#共同通讯), Su Z#. 2017. Differential deposition of H2A.Z in combination with histone modifications within related genes in rice callus and seedling. Plant J,89:264-27712.Fang Y, Wang L,Wang XM,YouQ, Pan XC, Xiao J, Wang XE, Wu YF, Su Z#, Zhang WL#(#共同通讯).2016. Histone modifications facilitate the coexpression of bidirectional promoters in rice. BMC Genomics 17:768 13.Fang Y, Wang XM, Wang L, Pan XC, Xiao J, Wang XE, Wu YF, Zhang WL(通讯).2016. Functional characterization of open chromatin in bidirectional promoters of rice. ScRep6:3208814.Zhu B*, Zhang WL*, Zhang T*, Liu B, Jiang JM. 2015. Open Chromatin Signature-based Enhancer Prediction and Validation in Arabidopsis thaliana. Plant Cell, 27:2415-2426 (*共同第一)15.Zhang T*, Zhang WL*, Jiang JM. 2015. Genome-Wide Nucleosome Occupancy and Positioning and Their Impact on Gene Expression and Genome Evolution in Plants. Plant Physiol. 168:1406-1416 (*共同第一)16.Zhang WL, Zhang T, Wu YF, Jiang JM (2014). Open chromatin in plant genomes. Cytogenetic and Genome Res. 143:18-27.17.Zhang T*, Talbert PB*, Zhang WL*, Wu YF, Yang ZJ, Henikoff J, HenikoffS, Jiang JM. 2013. The CentO satellites confers translational and rotational phasing on cenH3 nucleosomes in rice centromeres.Proc. Natl. Acad. Sci. USA. 110: E4875-E4883(*共同第一).18.Zhang WL, Zhang T, Wu YF, and Jiang JM. 2012. Mapping regulatory DNA elements and protein-binding footprints using signatures of open chromatin in Arabidopsis thaliana. Plant Cell, 24:2719-2731.19.Zhang WL, Wu YF, Schnable JC, Zeng ZX, Freeling M, Crawford GE, and Jiang JM. 2012. High-resolution mapping of open chromatin in the rice genome. Genome Res. 22: 151-162.20.Zhang WL, Friebe B, Gill BS, and Jiang JM. 2010. Centromere inactivation and epigenetic modifications of a plant chromosome with three functional centromeres. Chromosoma119: 553-63. 21.Zhang WL, Wang XE, Yu QY, Ming R, and Jiang JM. 2008.DNA methylation and heterochromatinization in the male-specific region of the primitive Y chromosome of papaya. Genome Res. 18: 1938-1943.22.Zhang WL, Lee H-R, Koo D-K, Jiang JM. 2008. Epigenetic modification of centromeric chromatin: Hypomethylation of DNA sequences in the CENH3-associated chromatin in Arabidopsis thalianaand maize. Plant Cell 20: 25-34.23.Zhang WL, Yi CD, Bao WD, Liu B, Cui JJ, Yu HX,Cao XF, Gu MH, Min Liu, and Cheng ZK.2005. The Transcribed 165-bp CentO is the major functional centromeric element in the wild rice species Oryza punctata. Plant Physiol. 139: 306-315.书本章节:1.Zhang AC, Li XX, Zhao HN, Jiang JM, Zhang WL(correspondence author). (2021). Genome-wide identification of open chromatin in plants using MH-seq.Methods in Molecular Biology(in press).2.Zhang WL(correspondence author) and Jiang JM (2018). Application of MNase-seq in the global mapping of nucleosome positioning in plants. In: Methods in Molecular Biology: Plant Transcription Factor. 1830:353-366.3.Zhang WLand Jiang JM (2015). Genome-wide mapping of DNaseI hypersensitive sites in plants. In: Methods in Molecular Biology:Plant Functional Genomics.1284:71-89.4.Zhang WL and Jiang JM(2014) Molecular Cytogenetics of Papaya. In: Genetics and Genomics of Papaya. Ray M and Moore P (ed.) Springer p157-167, ISBN: 978-1-4614-8086-0 (Print)978-1-4614-8087-7会议报告:1.Wenli Zhang(报告人) Functional Characterization of non-B DNA Structures in Plants. National Congress of Crop Science. Oct. 27-30, 2019. Blossom Water Museum Hotel, Hangzhou, China. 2.Wenli Zhang (报告人)Open chromatin associated with plant genome. National Congress of Plant Biology. Oct.9-11, 2013. Zhongshan Hotel, Nanjing, China.3.Wenli Zhang (报告人), Chingman Wai, Qingyi Yu, Ray Ming, and Jiming Jiang. Cytological characterization of the papaya genome. In: Abstract of Plant &Animal Genomics XX Conference. Jan. 14-18, 2012. Town & Country Convention Center, San Diego, CA.USA. P:W310.4.Wenli Zhang (报告人), Xiue Wang, Qingyi Yu, Ray Ming, and Jiming Jiang.Epigenetic modifications in the male-specific region of the primitive Y chromosome of papaya. In: Abstract of Plant &Animal Genomics XVII Conference. Jan. 10-14, 2009. Town & Country Convention Center, San Diego, CA.USA. P:W355.招生招聘:欢迎对植物表观遗传学,生物信息和表观基因组学研究方向感兴趣,具有生物信息,生化和分子生物学等研究背景的优秀毕业生加入;同时热忱欢迎对本实验室研究方向感兴趣的学生前来攻读硕、博士学位