杨东雷教授,博士生导师,江苏省杰出青年基金获得者办公室:理科楼A220电子邮箱:dlyang@njau.edu.cn 联系电话:025-84396559研究经历:长期以水稻和拟南芥为材料从事表观遗传学与植物免疫学研究。研究成果在Nature Plants, PNAS, Cell Research, Cell Host&Microbe, Molecular Plant, Plant Physiology,New Phytologist等杂志上发表30余篇。现在主要研究水稻抗病与生长发育之间的交叉对话、小RNA介导的DNA甲基化分子途径,表观遗传学调控水稻的抗病与产量性状发育等。研究领域:作物免疫、激素信号、抗病与生长发育互作、DNA甲基化、smallRNA,表观遗传学教育经历:2003.08-2009.11:中国科学院,上海生命科学研究院,植物生理与生态研究所,博士1999.09-2003.06:山东大学,生命科学学院,生物科学专业,学士工作经历:2015.01-至今南京农业大学,农学院教授,博士生导师2012. 01-2014.12 中国科学院,上海植物逆境生物学研究中心,美国科学院院士朱健康实验室担任副研究员2011.01-2011.12:美国普渡大学,农学院美国科学院院士朱健康实验室从事博士后研究2009.12-2010.12:美国康奈尔大学,农学院华健教授实验室从事博士后研究
代表性文章:1. LiuM(#), Shi Z(#), Zhang X, Wang M, Zhang L, Zheng K, Liu J, Hu X, DiC, Qian Q, He Z, Yang DL(*). Inducible overexpression of Ideal Plant Architecture1improves both yield and disease resistance in rice. Nat. Plants. 2019(IF2017=11.471)2. Yang DL(#)(*), Zhang G, Wang L, Li J, Xu D, Di C, Tang K, Yang L, Zeng L, Miki D, Duan CG, Zhang H, Zhu JK(*).Four putative SWI2/SNF2 chromatin remodelers have dual roles in regulating DNA methylation in Arabidopsis.Cell Discov.2018 Oct 16;4:55. doi: 10.1038/s41421-018-0056-8.(IF2017=4.462)3. Li Y(#), Guo J, Yang Z, Yang DL(*).Plasma Membrane-Localized Calcium Pumps and Copines Coordinately Regulate Pollen Germination and Fertility in Arabidopsis.(2018).Int J Mol Sci. 19(6). pii: E1774. doi: 10.3390/ijms19061774.(IF2017=3.687)4. Yang DL(#)(*), Shi Z(#), Bao Y(#), Yan J(#), Yang Z, Yu H, Li Y, Gou M, Wang S, Zou B, Xu D, Ma Z, Kim J, Hua J(*). (2017). Calcium pumps and interacting BON1 protein modulate calcium signature, stomatal closure, andplantimmunity.PlantPhysiol.175(1):424-437.(IF2017=5.949)5. Li X(#), Yang DL(#), Sun L(#), Li Q, Mao B, He Z(*).(2016). The Systemic Acquired Resistance Regulator OsNPR1 Attenuates Growth by Repressing Auxin Signaling through Promoting IAA-Amido Synthase Expression.Plant Physiol.172(1):546-558.(IF2017=5.949)6. Yang DL(#),Zhang G(#), Tang K, Li J, Yang L, Huang H, Zhang H, Zhu JK(*). (2016). Dicer-independent RNA-directed DNA methylation in Arabidopsis. Cell Res. 26(1): 66-82. (IF2017=15.393)7. Zou B(#), Yang DL(#), Shi Z(#), Dong H, Hua J(*).(2014).Monoubiquitination of Histone 2B at the disease resistance gene locus regulates its expression and impacts immune responses in Arabidopsis. Plant Physiol.165(1):309-318.(IF2017=5.949)8. Sun L(#), Yang DL(#),Kong Y, Chen Y, Li XZ, Zeng LJ, Li Q, Wang ET,He ZH(*).(2014).Sugar homeostasis mediated by cell wall invertase GRAIN INCOMPLETE FILLING 1 (GIF1) plays a role in pre-existing and induced defence in rice. Mol.PlantPathol.15(2):161-173.(IF2017=4.188)9. Yang DL(#), Yang Y, He Z(*). (2013). Roles ofplanthormones and their interplay in rice immunity. MolPlant.6(3):675-685.(IF2017=9.326)10.Yang DL(#), Dong WX(#), Zhang YY, He ZH(*).(2013).Gibberellins modulate abiotic stress tolerance in plants. Scientia Sinica.43(12): 1119-112611.Yang DL(#), Yao J(#), Mei CS(#),Tong XH, Zeng LJ, Li Q, Xiao LT, Sun TP, Li J, Deng XW, Lee CM, Thomashow MF, Yang Y(*), He Z(*), He SY(*). (2012). Plant hormone jasmonate prioritizes defense over growth by interfering with gibberellin signaling cascade. Proc Natl Acad Sci USA. 109(19):E1192-1200.(IF2017=9.504)12.Yang DL(#), Li Q, Deng YW, Lou YG, Wang MY, Zhou GX, Zhang YY, He ZH(*). (2008). Altered disease development in the euimutants and Eui overexpressors indicates that gibberellins negatively regulate rice basal disease resistance. Molecular Plant. 1:528-537. (IF2017=9.326)13. Zhang Q, Liang Z, Cui X, Ji C, Li Y, Zhang P, Liu J, Riaz A, Yao P, Liu M, Wang Y, Lu T, Yu H, Yang D, Zheng H, Gu X.(2018). N6-Methyladenine DNA Methylation in Japonica and Indica Rice Genomes and Its Association with Gene Expression, Plant Development and Stress Responses.Mol Plant. 2018 Nov 15. pii: S1674-2052(18)30341-1.(IF2017=9.326)14. Wang L, Yuan J, Ma Y, Jiao W, Ye W,Yang DL, Yi C, Chen ZJ.(2018). Rice Interploidy Crosses Disrupt Epigenetic Regulation, Gene Expression, and Seed Development.Mol Plant.11:300-314.(IF2017=9.326)15. You Q(#), Zhai K(#), Yang D, Yang W, Wu J, Liu J, PanW, Wang J, Zhu X, Jian Y, Liu J, Zhang Y, Deng Y, Li Q, Lou Y, Xie Q, He Z(*).(2016). An E3Ubiquitin Ligase-BAG Protein Module Controls Plant Innate Immunity and Broad-Spectrum Disease Resistance.Cell Host&Microbe.20(6):758-769.(IF2017=17.872)16. Yuan J(#), Chen S(#), Jiao W(#), Wang L, Wang L, Ye W, Lu J, Hong D, You S, Cheng Z, Yang DL, Chen ZJ.(2017). Both maternally and paternally imprinted genes regulate seed development inrice.New Phytol. 216(2):373-387.(IF2017=7.433)17.Xu J(#), Zhang L, Yang DL, Li Q, He Z(*).(2015). Thymidine kinases shareaconservedfunctionfornucleotidesalvageandplayanessentialroleinArabidopsisthalianagrowthanddevelopment. New Phytol.208(4): 1089-1103.(IF2017=7.433)18. Feng Z(#), Zhang B(#), Ding W, Liu X, Yang DL, Wei P, Cao F, Zhu S, Zhang F, Mao Y, Zhu JK(*).(2013). Efficient genome editing inplantsusing a CRISPR/Cas system. Cell Res.23(10):1229-1232.(IF2017=15.393)19. Feng Z(#), Mao Y, Xu N, Zhang B, Wei P, Yang DL, Wang Z, Zhang Z, Zheng R, Yang L, Zeng L, Liu X, Zhu JK(*).(2014). Multigeneration analysis reveals the inheritance, specificity, and patterns of CRISPR/Cas-induced gene modifications in Arabidopsis. Proc Natl Acad Sci USA. 111(12):4632-4637. (IF2017=9.504)20. Yuan Y(#), Zhong S, Li Q, Zhu Z, Lou Y, Wang L, Wang J, Wang M, Li Q,Yang DL, He Z(*).(2007). Functional analysis of rice NPR1-like genes reveals that OsNPR1/NH1 is the rice orthologue conferring disease resistance with enhanced herbivore susceptibility. Plant Biotechnol J.5(2):313-324.(IF2017=6.305)专著:何祖华,王牧阳,杨东雷第八章:水杨酸,218页-230页《植物激素作用的分子机理》许智宏薛红卫主编,上海科学技术出版社出版,2012年10月主持的科研项目:1.江苏省自然科学基金-杰出青年基金,SBK2017010093, 激素互作调控水稻抗病-产量性状平衡的机制,2017/07-‐2020/06,100万,主持2.国家重点研发计划“七大作物育种”,2016YFD0100603-9,主要农作物抗病虫抗逆性状形成的分子基础,2016/07-2020/12,140万, 子课题负责人3.转基因专项,2016ZX08001002, 抗病转基因水稻新品种培育,在研,2016/01-2020/12,在研,62万,子课题负责人4.国家自然科学基金面上项目,31671340,一个新的RdRP基因调控水稻DNA甲基化与基因表达的机制研究,2017/01-2020/12,62万,主持5. 南京农业大学高层次人才启动费,2015/01-2019/12,100万,主持6. 江苏省自然基金委-青年基金,BK20150659, miR156-OsSPL14调控水稻抗白叶枯病的分子机理解析,2015/07-2018/06,20万,主持7. 中央高校基本业务费,2015/01-2020/12,50万,主持8. 作物遗传与种质创新国家重点实验室自主课题,20万,主持9. 江苏省作物学优势学科,40万,主持