学术学位博导
--> 职称：教授
**
单位：神经生物学系
gaojun@njmu.edu.cn
专业：神经生物学
个人简介
发表论文:
Maged1 co-interacting with CREB through a hexapeptide repeat domain regulates learning and memory in mice.
A novel pathway regulates memory and plasticity via SIRT1 and miR-134
Resveratrol improves learning and memory in normally aged mice through microRNA -CREB pathway.
SIRT1 activation as a caloric restriction-mimetic to delay the onset of neurodegeneration.
SIRT1 collaborates with ATM and HDAC1 to maintain genomic stability in neurons
Synaptic Deficits Are Rescued in the p25/Cdk5 Model of Neurodegeneration by the Reduction of β-Secretase (BACE1)
Cdk5 is required for memory function and hippocampal plasticity via the cAMP signaling pathway.
Critical-size calvarial bone defects healing in a mouse model with silk scaffolds and SATB2-modified iPSCs.
Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy.
PDK1 deficit impairs the development of the dentate gyrus in mice
教材专著:
科研成果:
酸敏感离子通道的生物学功能、工作原理和病理意义
一种树鼩活动性行为监测箱
小动物触摸屏条件行为操作系统V1.0
目前承担的科研项目:
疾病与学习记忆损伤
遗忘的功能和机制研究
miRNA-137在脑缺血性损伤和功能障碍中的调控研究
恒定菌群移植抗焦虑效应及其调控苯二氮卓结合抑制蛋白DBI的机制
疾病与学习记忆损伤
利用外泌体靶向治疗缺血性脑卒中的研究
认知功能障碍的转化研究
Maged1介导的自噬及凋亡信号通路在PD发生发展中的作用研究
已经完成的科研项目:
PP2A在AD中的作用研究
酸敏感离子通道在药物成瘾中作用研究
疾病与学习记忆损伤
