学术学位博导
--> 职称：教授
**
单位：病理生理学系
yjxu@njmu.edu.cn
专业：病理学与病理生理学（病理生理学）
个人简介
发表论文:
MKL1 potentiates lung cancer cell migration and invasion by epigenetically activating MMP9 transcription.
MKL1 defines the H3K4Me3 landscape for NF-kB dependent inflammatory response.
The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction.
Angiogenic factor with G patch and FHA domains 1 (Aggf1) is a novel regulator of vascular injury.
Histone methyltransferase SUV39H1 mediated SIRT1 trans-repression contributes to cardiac ischemia-reperfusion injury.
The histone methyltransferase Suv39h2 contributes to non-alcoholic steatohepatitis in mice.
PIASy mediates hypoxia-induced transcriptional repression of SIRT1 gene and epithelial-to-mesenchymal transition by hypoxia in ovarian cancer cells.
MRTF-A programs epigenetic activation of hepatic stellate cells.
Endothelial MRTF-A mediates Angiotensin II induced cardiac hypertrophy.
Megakaryocytic leukemia 1 (MKL1) directs an H3K4 methyltransferase complex to regulate hypoxic pulmonary hypertension.
教材专著:
科研成果:
目前承担的科研项目:
Brg1调控血管内皮细胞稳态的机制及其在心肌肥大中的作用研究
H3K9甲基转移酶SUV39H1调控血管平滑肌表型转化的表观遗传机制研究
心血管系统稳态失衡的转录调控
PPARg/CIITA复合物对I型胶原基因(COL1A2)的转录调控
HIC1调控CIITA转录机制研究及其在B细胞分化中的意义
已经完成的科研项目:
