学术学位博导
--> 职称:副教授
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单位:营养与食品卫生学系
liyuan@njmu.edu.cn
专业:营养与食品卫生学
个人简介
发表论文:
14-3-3η is a novel growth-promoting and angiogenic factor in hepatocellular carcinoma
Blocking of STAT-3/SREBP1-mediated glucose-lipid metabolism is involved in dietary phytoestrogen-inhibited ovariectomized-induced body weight gain in rats
The ROS-mediated activation of IL-6/STAT3 signaling pathway is involved in the 27-hydroxycholesterol induced cellular senescence in nerve cells
Arsenic trioxide reverses the chemo-resistance in hepatocellular carcinoma: a targeted intervention of 14-3-3η/NF-κB feedback loop
Reversal of sorafenib resistance in hepatocellular carcinoma: epigenetically regulated disruption of 14-3-3η/hypoxia inducible factor-1α
27-Hydroxycholesterol-induced EndMT acts via STAT3 signaling to promote breast cancer cell migration by altering the tumor microenvironment
教材专著:
科研成果:
砷暴露所致肺和皮肤损害及肿瘤的分子机制研究
肿瘤标志蛋白抑制剂及其在抑制肿瘤标志蛋白中的应用
目前承担的科研项目:
规范化大型胃癌队列的建立及其可用性研究(SQ2017YFSF090061)
14-3-3η在肝癌索拉菲尼抵抗中的作用机制及三氧化二砷对其靶向干预研究(JX21817902/006)
基于氧化/磷酸化调控蛋白14-3-3η为靶点,研发精准靶向肝癌耐药细胞亚群的小分子化合物及其作用机制研究
精准靶向14-3-3η在传统中药三氧化二砷 逆转肝癌Sorafenib抵抗中的作用及机制研究
已经完成的科研项目: