学术学位博导
--> 职称：教授
单位：临床药学系
ychen@njmu.edu.cn
专业：临床药学
个人简介
发表论文:
Acid-Sensitive Peptide-Conjugated Doxorubicin Mediates the Lysosomal Pathway of Apoptosis and Reverses Drug Resistance in Breast Cancer.
Simultaneous Quantification of Protein Phosphorylation Sites using Liquid Chromatography−Tandem Mass Spectrometry-Based Targeted Proteomics: A Linear Algebra Approach for Isobaric Phosphopeptide
A liquid chromatography–tandem mass spectrometry-based targeted proteomics assay for monitoring P-glycoprotein levels in human breast tissue
An investigation of heat protein 27 and P-glycoprotein mediated multi-drug resistance inbreast cancer using liquid chromatography-tandem mass spectrometry-based targeted proteomics
A liquid chromatography-tandem mass spectrometry-based targeted proteomics approach for the assessment of transferrin receptor levels in breast cancer
Quantitative subcellular study of transferrin receptor-targeted doxorubicin and its metabolite in human breast cancer cells
Comparison of Liquid Chromatography-Tandem Mass Spectrometry-based Targeted Proteomics and Conventional Analytical Methods for the Determination of P-glycoprotein in Human Breast Cancer Cells
Nodularins in poisoning
A liquid chromatography-tandem mass spectrometry method for the determination of nodularin-R in human plasma and its preliminary clinical application
Subcellular Quantification of Doxorubicin and its Metabolite in Cultured Human Leukemia Cells using Liquid Chromatography-Tandem Mass Spectrometry
教材专著:
科研成果:
陈芸, 徐金慧, 盛媛, 许飞飞, 方丹君, 尤一雯, 肿瘤靶向多肽-阿霉素衍生物及其制备方法和应用
江苏省第五期“333高层次人才培养工程”
第六批江苏省六大人才高峰
目前承担的科研项目:
基于质谱的定向蛋白组学对细胞因子和肿瘤多药耐药相关性的研究 (21175071）
定向蛋白质组学定量研究乳腺癌生物标志物的新策略
东南大学-南京医科大学合作项目重点项目
蒽环类药物与内源性靶分子细胞毒性作用机制的亚细胞药代动力学研究
基于质谱的定向蛋白组学对细胞因子和肿瘤多药耐药相关性的研究
固定化DNA-多肽探针-准定向蛋白质组学定量研究乳腺癌相关的microRNAs
已经完成的科研项目:
