学术学位硕导
--> 职称:教授
-3525
学院:药学院
qiuling@jsinm.org
专业:医学技术
http://www.jsinm.org/cxywyjzx/1962.shtml
个人简介
邱玲,女,1980年生,博士,研究员,硕士生导师。江苏省医学拔尖人才、江苏省“333高层次人才培养工程”第三层次培养对象、江苏省“十二五科教兴卫工程”医学重点人才、江苏省“十三五科教强卫工程”青年医学重点人才、无锡市青年岗位能手标兵、江苏省医学会核医学分会第八届和第九届显像学组委员及多个国际期刊审稿人。近年来主要从事肿瘤靶向特异性诊治药物的设计合成及其应用基础研究,作为项目负责人主持完成了国家自然科学基金、江苏省自然科学基金、吴阶平医学基金、无锡市卫健委重点项目、无锡市留学归国人员项目等十余项科研项目;以第一作者和通讯作者在《Analytical Chemistry,IF=6.785》《Theranostics,IF=8.063》、《Journal of Nuclear Medicine,IF=7.354》、《Chemical Communications,IF=6.164》等专业领域权威期刊上发表研究论文70余篇;获得国家发明专利授权16项(第一发明人5项)、实用新型专利授权4项(均为第一发明人);获得全国商业科技进步奖一等奖/三等奖各1项、江苏省医学新技术引进奖一等奖2项、江苏医学科技奖三等奖1项、江苏省优秀博士学位论文、全国百名优秀博士学位论文提名奖等学术奖励。
发表论文:
99mTc-labeled butyl-substituted zoledronic acid as a novel potential SPECT imaging agent: preparation and preclinical pharmacology study
Preparation and in vivo biological investigation of 99mTc-HEIDP as a novel radioligand for bone scanning.
Preparation and in vivo biological investigations on a novel radioligand for bone scanning: Technetium-99m labeled zoledronic acid derivative
A Series of Imidazolyl-Containing Bisphosphonates with Abundant Hydrogen-Bonding Interactions: Syntheses, Structures and Bone-Binding Affinity
Synthesis and pharmacological evaluation of 99mTc-labeled imidazolyl-containing diphosphonic acid as a novel bone imaging agent
Synthesis and evaluation of a series of 99mTc-labelled zoledronic acid derivatives as potential bone seeking agent
Synthesis and biological evaluation of a series of 99mTc-labeled disphosphonates as novel radiotracers with improved bone imaging
Development of superior bone scintigraphic agent from a series of 99mTc-labeled zoledronic acid derivatives
A novel 99mTc-labeled dimethyl-substituted zoledronic acid (DMIDP) with improved bone imaging efficiency.
Insights into the Nature of Anesthetic-Protein Interactions: An ONIOM Study
教材专著:
高能量密度材料的理论设计
科研成果:
江苏省优秀博士学位论文
全国优秀博士学位论文提名奖
目前承担的科研项目:
新型铂-唑来膦酸类骨靶向抗癌药物的研制
新型铂-唑来膦酸类配合物的设计合成及生物活性研究
已经完成的科研项目:
99mTc标双膦酸盐类骨肿瘤诊治剂的计算机辅助设计与合成
新型唑来膦酸类化合物的设计、合成及抗肿瘤活性研究(
新型骨肿瘤诊治剂的计算机辅助设计及其合成与活性研究
新型99mTc 标记甲磺酰苯胺类分子探针的研制及其对乳腺癌靶向显像和治疗作用研究