学术学位博导
--> 职称：教授
单位：第一附属医院
dinggx@njmu.edu.cn
专业：老年医学
个人简介
内分泌博士，教授、主任医师，博士生导师
发表论文:
Comparison of gene transcription between subcutaneous and visceral adipose tissue in Chinese adults.
Regional differences in gene expression between subcutaneous and visceral adipose tissue.
11 beta-hydroxysteroid dehydrogenase type 1 promotes differentiation of 3T3-L1 preadipocyte.
Adipose tissue-targeted 11β-hydroxysteroid dehydrogenase type 1 inhibitor protects against diet-induced obesity.
One-step construction of Lentiviral reporter Using Red-Mediated Recombination.
Essential roles of 11b-HSD1 in regulating brown adipocyte function
BVT.2733, a selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitor, attenuates obesity and inflammation in diet-induced obese mice.
Glucocorticoids Transcriptionally Regulate miR-27b Expression Promoting Body Fat Accumulation Via Suppressing the Browning of White Adipose Tissue
Determination of UCP1 expression in subcutaneous and perirenal adipose tissues of patients with hypertension
Establishment of TBS reference plots and correlationbetween TBS and BMD in healthy mainland Chinese women
教材专著:
临床药物学
实用临床治疗药典
实用内分泌诊疗手册
科研成果:
一种棕色脂肪组织靶向性多肽及其应用
一种靶向至白色脂肪组织治疗代谢综合征的新型靶向药物
一种靶向至棕色脂肪组织治疗肥胖的新型靶向药物
代谢表型为导向的2型糖尿病个体化诊疗及其机理研究
目前承担的科研项目:
热卡限制类似方法——11β-HSD1抑制剂防治心肌纤维化机制研究
糖皮质激素差异调控脂肪祖细胞米色化的细胞特异性研究
已经完成的科研项目:
特异性11-HSD1靶向抑制剂治疗代谢综合症的作用机制研究
江苏省卫生厅兴卫工程领军人才课题——代谢综合征发病机制及靶向胰岛素增敏剂研究
脂肪组织源干细胞治疗骨质疏松的基础和临床研究
棕色脂肪靶向11β-HSD1抑制剂治疗肥胖的作用机制研究
南京医科大学第一附属医院“代谢与衰老”创新团队工程项目
mir149、mir137调控糖皮质激素促进内脏肥胖的分子机制研究
江苏高校优势学科建设工程一期项目
