学术学位博导
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-5021
单位：第一附属医院
liuli@njmu.edu.cn
专业：老年医学
个人简介
刘莉，女，1965年出生，内科学（心血管病）博士学位，南京医科大学第一附属医院老年医学博士研究生导师。近10年承担国家自然科学基金项目6项，在SCI收录期刊发表论著40余篇，获得江苏省科技进步奖二等奖、江苏省医学科技奖二等奖等。
发表论文:
HSPA12A is required for adipocyte differentiation and diet-induced obesity through a positive feedback regulation with PPARγ
HSPA12A Is a Novel Player in Nonalcoholic Steatohepatitis via Promoting Nuclear PKM2-Mediated M1 Macrophage Polarization
Cardiomyocyte-specific deficiency of HSPB1 worsens cardiac dysfunction by activating NFκB-mediated leucocyte recruitment after myocardial infarction
Inhibition of A-Type K+ Channels by Urotensin-II Induces Sensory Neuronal Hyperexcitability Through the PKCα-ERK Pathway
HSPA12B Attenuated Acute Myocardial Ischemia/reperfusion Injury via Maintaining Endothelial Integrity in a PI3K/Akt/mTOR-dependent Mechanism
HSP27 Alleviates Cardiac Aging in Mice via a Mechanism Involving Antioxidation and Mitophagy Activation
HSPA12B attenuates acute lung injury during endotoxemia in mice
HSPA12B: a novel facilitator of lung tumor growth.
Class III PI3K-mediated prolonged activation of autophagy plays a critical role in the transition of cardiac hypertrophy to heart failure
HSPA12B inhibits lipopolysaccharide-induced inflammatory response in human umbilical vein endothelial cells
教材专著:
老年医学
科研成果:
心肌老化的分子机制及其保护的系列研究
HSP27和HSPA12B对心肌损伤的保护作用及机制研究
目前承担的科研项目:
巨噬细胞HSPA12A基因沉默对Ⅱ型糖尿病的保护作用及机制研究
HSPA12A基因沉默对非酒精性脂肪肝病的保护作用及机制研究
新基因HSPA12A对脑卒中的保护作用及机制研究
心血管病转化医学 (子课题)
已经完成的科研项目:
HSPA12B对脑卒中后功能障碍的修复作用及机制研究
Hsp27对心脏衰老的延缓作用及机制研究
HSPA12B对脑梗塞的保护作用及其机制研究
热休克蛋白27抑制内毒素心功能不全的机制研究
Hsp27改善急性心梗后慢性心力衰竭的实验研究
胰岛素样生长因子1基因工程产物纯化及检测试剂盒的研制开发
稳定高度表达HSP25对抗大鼠心肌细胞老化的影响
HSP27心肌特异性转基因鼠建立及其对心肌老化的影响
