学术学位博导
--> 职称：教授
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单位：办公室
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专业：生殖医学
个人简介
发表论文:
Transient estrogen receptor binding and p300 redistribution support a squelching mechanism for estradiol-repressed genes
Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation
The role of MATER in endoplasmic reticulumdistribution and calcium homeostasis in mouse oocytes
PAD1 promotes epithelial-mesenchymal transition and metastasis in triple-negative breast cancer cells by regulating MEK1-ERK1/2-MMP2 signaling.
Perfluorooctanoic acid induces human Ishikawa endometrial cancer cell migration and invasion through activation of ERK/mTOR signaling
Peptidylarginine deiminase 1-catalyzed histone citrullination is essential for early embryo development
Role for PADI6 in securing the mRNA-MSY2 complex to the oocyte cytoplasmic lattices
Targeted H3R26 deimination specifically facilitates estrogen receptor binding by modifying nucleosome structure.
Genome-wide analysis reveals PADI4 cooperates with Elk-1 to activate c-Fos expression in breast cancer cells
Perfluorooctanoic acid stimulates ovarian cancer cell migration, invasion via ERK/NF-κB/MMP-2/-9 pathway.
教材专著:
科研成果:
美国苏珊科曼乳腺癌基金会博士后研究基金奖
美国康奈尔大学比较癌症生物学培训研究基金奖
2014年南京医科大学校特聘教授
2014 年度江苏省“双创团队”核心成员
目前承担的科研项目:
PADI2对雌激素应答基因转录调控机制及其在乳腺癌发生发展中的作用,81372850
PADI抑制剂对乳腺癌细胞的抑制效应及其作用机制,15KJA320003
南京医科大学人才引进启动基金
母源性因子控制卵母细胞成熟与早期胚胎发育
肾母细胞瘤基因WT1在上皮性卵巢癌侵袭转移中的作用研究
已经完成的科研项目:
