李娴静，博士，硕士生导师。2016年毕业于中国药科大学生命科学与技术学院，获得博士学位。毕业后进入中国药科大学药物科学研究院新药安全评价研究中心任教，主要从事肿瘤免疫学研究。以第一作者/共同第一作者或通讯作者在国际知名期刊PNAS、Gut及FASEB J等发表SCI论文7篇。主持国家及江苏省自然科学基金青年项目各一项，作为骨干成员参与“十三五“新药创制重大专项（2018ZX**-006）、重大研究计划培育（**）及集成项目（**）各一项。
联系方式：xjl@cpu.edu.cn
研究内容：
1. 巨噬细胞活化对炎症性疾病的调节作用及分子机制
2. 肿瘤相关巨噬细胞代谢特征、分子机制及干预策略
代表性论文：
1. Ye Zhang^#, Xue Yang^#, Wenchao Yan, Rui Li, Qian Ye, Linjun You, Wenhao Xie, Kun Mo, Ruifeng Fu, Yanxiang Wang, Yufei Chen, Hui Hou, Yong Yang, Lutz Birnbaumer*, Qin Di*, Xianjing Li*.Thymopentin improves the survival of septic mice by promoting the production of 15-deoxy-prostaglandin J2 and activating the PPARγ signaling pathway. FASEB J. 2020 Jul 11. doi: 10.1096/fj.R. Epub ahead of print. (IF=4.99)
2. Duowei Wang^#, Xianjing Li^#, Jiani Li^#, Yuan Lu#, Sen Zhao, Xinying Tang, Xin Chen, Jiaying Li, Yan Zheng, Shuran Li, Rui Sun, Ming Yan, Decai Yu, Guangwen Cao, Yong Yang*. APOBEC3B interaction with PRC2 modulates microenvironment to promote HCC progression. Gut. 2019 Oct; 68(10):1846-1857. (IF=19.8)
3. Xianjing Li^#, Duowei Wang^#, Zhen Chen^#, Ermei Lu, Zhuo Wang, Jingjing Duan, Wei Tian, Yun Wang, Linjun You, Yulian Zou, Yan Cheng, Qingyi Zhu, Xiaojian Wan, Tao Xi, Meisheng Jiang, Yuyuan Han, Cong Cao, Lutz Birnbaumer*, Wen-Ming Chu*,Yong Yang*. Gαi1 and Gαi3 Regulate Macrophage Polarization by Forming a Complex Containing CD14 and Gab1. Proc Natl Acad Sci U S A.2015 ;112(15):4731-6.(IF=9.5)
4. Xianjing Li^#, Wang Zhuo^#, Yulian Zou^#, Ermei Lu, Jingjing Duan, Hongbao Yang, Qijin Wu, Xiaona Zhao, Yun Wang, Linjun You, Ling He, Tao Xi^*, Yong Yang^*. Pretreatment with lipopolysaccharide attenuates diethylnitrosamine-caused liver injury in mice via TLR4-dependent induction of Kupffer cell M2 polarization.Immunol Res. 2015;62(2):137-45. (IF=2.9)