徐春明
东北师范大学生命科学学院
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职　　称：副教授
研究方向：基因组学/表观遗传学
办公电话：
办公地点：
电子邮件：xucm848@nenu.edu.cn



个人简历
2006-2011年获得东北师范大学植物学博士学位，主要研究方向为植物表观遗传学和基因组学。2010-2011年公派至Iowa State University学习分子进化与生物信息学。2011年加入东北师范大学分子表观遗传学教育部重点实验室。2015-2018年至美国University of Georgia进行博士后研究，主要研究内容包括机器学习在复杂性状和基因组研究中的应用，杂交与多倍化对基因组范围表观遗传与基因表达的影响等。在国际主流学术杂志上发表和参与发表多篇研究论文，包括MBE，Nature，PNAS，Plant Cell，Plant Journal，Plant Physiology等。2006/9-2011/7，东北师范大学，植物学，博士2002/9-2006/7，黑龙江大学，生物工程，本科2010/3-2011/3，Iowa State University，Department of Ecology, Evolution, and Organismal Biology，联合培养博士2011/7-2014/6，东北师范大学，生命科学学院，讲师2015/5-2018/12，University of Georgia, 博士后2014/7-至今，东北师范大学，生命科学学院，副教授发表论文：2018Xu C*, Nadon BD, Kim KD, Jackson SA*. (2018) Genetic and epigenetic divergence of duplicate genes in two legume species. Plant Cell Environ. 41:2033-2044 (* Corresponding author)Gao D, Chu Y, Xia H, Xu C, Heyduk K, Abernathy B, Ozias-Akins P, Leebens-Mack JH, Jackson SA. (2018) Horizontal Transfer of Non-LTR Retrotransposons from Arthropods to Flowering Plants. Mol Biol Evol 35:354-364.2017Sun Y, Wu Y, Yang CW, Sun S, Lin XY, Liu LX, Xu CM, Wendel JF, Gong L, Liu B. (2017) Segmental allotetraploidy generates extensive homoeologous expression rewiring and phenotypic diversity at the population level in rice. Molecular Ecology 26:5451-5466.2016Wu Y, Sun Y, Wang X, Lin X, Sun S, Shen K, Wang J, Jiang T, Zhong S, Xu C*, Liu B* (2016) Transcriptome shock in an interspecific F1 triploid hybrid of Oryza revealed by RNA sequencing. J Integr Plant Biol 58:150-164. (* Corresponding author)Wang XT, Hu LJ, Wang XF, Li N, Xu CM, Gong L, Liu B. (2016) DNA Methylation Affects Gene Alternative Splicing in Plants: An Example from Rice. Molecular Plant 9:305-307.2015Ou XF, Zhuang TT, Yin WC, Miao YL, Wang B, Zhang YH, Lin XY, Xu CM, von Wettstein D, Rustgi S, Liu B. (2015) DNA Methylation Changes Induced in Rice by Exposure to High Concentrations of the Nitric Oxide Modulator, Sodium Nitroprusside. Plant Molecular Biology Reporter 33:1428-1440.Li N, Chen YR, Ding Z, Li P, Wu Y, Zhang A, Yu S, Giovannoni JJ, Fei Z, Zhang W, Xiang, J. Z. Xu, C.* Liu, B. Zhong, S.* (2015) Nonuniform gene expression pattern detected along the longitudinal axis in the matured rice leaf. Sci Rep 5:8015. (* Corresponding author)2014Hu, L.J.?, Li, N?, Xu C.?, Zhong, S.L.?, Lin, X.Y., Yang, J.J., Zhou, T.Q., Yuliang, A.Z., Wu,Y., Chen, Y.R., Cao, X.F., Zemach, A., Rustgi, S., von Wettstein, D., and Liu, B. (2014). Mutation of a major CG methylase in rice causes genome-wide hypomethylation, dysregulated genome expression, and seedling lethality. Proc Natl Acad Sci U S A 111(29): p. 10642-10647. (? Equal contributors)Xu, C?, Bai, Y.?, Lin, X., Zhao, N., Hu, L.J., Gong, Z, Wendel, J.F., and Liu, B. (2014). Genome-wide disruption of gene expression in allopolyploids but not hybrids of rice subspecies. Mol. Biol. Evol. 31(5):1066–1076. (? Equal contributors)Zhang, H., Zhu, B., Qi, B., Gou, X., Dong, Y., Xu, C., Zhang, B., Huang, W., Liu, C., Wang, X., Yang, C., Zhou, H., Kashkush, K., Feldman, M., Wendel, F.J. and Liu, B. (2014). Evolution of the BBAA Component of Bread Wheat during Its History at the Allohexaploid Level. The Plant Cell 26(7): p. 2761-2776.Zhang, D., Wang, Z., Wang, N., Gao, Y., Liu, Y., Wu, Y., Bai, Y., Zhang, Z., Lin, X., Dong, Y., Ou, X., Xu, C.*, Liu, B.* (2014). Tissue Culture-Induced Heritable Genomic Variation in Rice, and Their Phenotypic Implications. PLoS One 7;9(5):e96879 (* Corresponding author)2013Zhang, H., Bian, Y., Gou, X., Dong, Y., Rustgi, S., Zhang, B., Xu, C., Li, N., Qi, B., Han, F., von Wettstein, D., and Liu, B. (2013). Intrinsic karyotype stability and gene copy number variations may have laid the foundation for tetraploid wheat formation. Proc Natl Acad Sci U S A 110, 19466-19471.Zhang, H., Bian, Y., Gou, X., Zhu, B., Xu, C., Qi, B., Li, N., Rustgi, S., Zhou, H., Han, F., Jiang, J., von Wettstein, D., and Liu, B. (2013). Persistent whole-chromosome aneuploidy is generally associated with nascent allohexaploid wheat. Proc Natl Acad Sci U S A 110, 3447-3452.Wang, Z., Zhang, D., Bai, Y., Zhang, Y., Liu, Y., Wu, Y., Lin, X., Wen, J., Xu, C., Li, L., and Liu, B. (2013). Genomewide variation in an introgression line of rice-Zizania revealed by whole-genome re-sequencing. Plos One 8, e74479.Wang, X., Wu, R., Lin, X., Bai, Y., Song, C., Yu, X., Xu, C., Zhao, N., Dong, Y., and Liu, B. (2013). Tissue culture-induced genetic and epigenetic alterations in rice pure-lines, F1 hybrids and polyploids. BMC Plant Biology 13.2012Paterson, A.H., Wendel, J.F., Gundlach, H., Guo, H., Jenkins, J., Jin, D.C., Llewellyn, D., Showmaker, K.C., Shu, S.Q., Udall, J., Yoo, M.J., Byers, R., Chen, W., Doron-Faigenboim, A., Duke, M.V., Gong, L., Grimwood, J., Grover, C., Grupp, K., Hu, G.J., Lee, T.H., Li, J.P., Lin, L.F., Liu, T., Marler, B.S., Page, J.T., Roberts, A.W., Romanel, E., Sanders, W.S., Szadkowski, E., Tan, X., Tang, H.B., Xu, C., Wang, J.P., Wang, Z.N., Zhang, D., Zhang, L., Ashrafi, H., Bedon, F., Bowers, J.E., Brubaker, C.L., Chee, P.W., Das, S., Gingle, A.R., Haigler, C.H., Harker, D., Hoffmann, L.V., Hovav, R., Jones, D.C., Lemke, C., Mansoor, S., Rahman, M.U., Rainville, L.N., Rambani, A., Reddy, U.K., Rong, J.K., Saranga, Y., Scheffler, B.E., Scheffler, J.A., Stelly, D.M., Triplett, B.A., Van Deynze, A., Vaslin, M.F.S., Waghmare, V.N., Walford, S.A., Wright, R.J., Zaki, E.A., Zhang, T.Z., Dennis, E.S., Mayer, K.F.X., Peterson, D.G., Rokhsar, D.S., Wang, X.Y., and Schmutz, J. (2012). Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres. Nature 492, 423-+.Ou, X., Zhang, Y., Xu, C., Lin, X., Zang, Q., Zhuang, T., Jiang, L., von Wettstein, D., and Liu, B. (2012). Transgenerational Inheritance of Modified DNA Methylation Patterns and Enhanced Tolerance Induced by Heavy Metal Stress in Rice (Oryza sativa L.). PloS One 7.Qi, B., Huang, W., Zhu, B., Zhong, X., Guo, J., Zhao, N., Xu, C., Zhang, H., Pang, J., Han, F., and Liu, B. (2012). Global transgenerational gene expression dynamics in two newly synthesized allohexaploid wheat (Triticum aestivum) lines. BMC Biology 10.Lin, C., Lin, X., Hu, L., Yang, J., Zhou, T., Long, L., Xu, C., Xing, S., Qi, B., Dong, Y., and Liu, B. (2012). Dramatic genotypic difference in, and effect of genetic crossing on, tissue culture-induced mobility of retrotransposon Tos17 in rice. Plant Cell Report 31, 2057-2063.2011Li, Y., Xia, Q., Kou, H., Wang, D., Lin, X., Wu, Y., Xu, C., Xing, S., and Liu, B. (2011). Induced Pib Expression and Resistance to Magnaporthe grisea are Compromised by Cytosine Demethylation at Critical Promoter Regions in Rice. Journal of Integrative Plant Biology 53, 814-823.Zhang, M., Xu, C., von Wettstein, D., and Liu, B. (2011). Tissue-Specific Differences in Cytosine Methylation and Their Association with Differential Gene Expression in Sorghum. Plant Physiology 156, 1955-1966.Zhao, N., Xu, L., Zhu, B., Li, M., Zhang, H., Qi, B., Xu, C., Han, F., and Liu, B. (2011). Chromosomal and genome-wide molecular changes associated with initial stages of allohexaploidization in wheat can be transit and incidental. Genome 54, 692-699.2009Zhang, M.?, Xu, C.?, Yan, H., Zhao, N., von Wettstein, D., and Liu, B. (2009). Limited tissue culture-induced mutations and linked epigenetic modifications in F-1 hybrids of sorghum pure lines are accompanied by increased transcription of DNA methyltransferases and 5-methylcytosine glycosylases. The Plant Jornal 57, 666-679. (? Equal contributors)Ngezahayo, F.?, Xu, C.?, Wang, H., Jiang, L., Pang, J., and Liu, B. (2009). Tissue culture-induced transpositional activity of mPing is correlated with cytosine methylation in rice. BMC Plant Biology 9. (? Equal contributors)Wang, H., Chai, Y., Chu, X., Zhao, Y., Wu, Y., Zhao, J., Ngezahayo, F., Xu, C.*, and Liu, B.* (2009). Molecular characterization of a rice mutator-phenotype derived from an incompatible cross-pollination reveals transgenerational mobilization of multiple transposable elements and extensive epigenetic instability. BMC Plant Biology 9. (* Corresponding author)Liu, B., Xu, C., Zhao, N., Qi, B., Kimatu, J.N., Pang, J., and Han, F. (2009). Rapid genomic changes in polyploid wheat and related species: implications for genome evolution and genetic improvement. Journal of Genetics and Genomics 36, 519-528.

社会兼职


吉林省遗传协会理事


获奖情况 （数据来源：科学技术处、社会科学处）


2014-11-04 吉林省科学技术奖自然科学奖二等奖


教学信息


表观遗传学生物信息学


科研信息 （数据来源：科学技术处、社会科学处）


项目：
1. 异源四倍体小麦形成早期实现细胞学二倍体化分子机制，2017年
2. 异源四倍体小麦中部分同源等位基因表达分歧的研究，2014年
3. 水稻亚种间新合成四倍体早期世代基因组变异，2014年
4. 高代稳定的新形成多倍体小麦性状变异的分子基础解析，国家自然科学基金委员会，2013年
5. 玉米自交系间器官发育时期特异DNA甲基化差异与相关基因表达和杂种优势的关系，国家自然科学基金委员会，2012年
论文：
1. Rapid and pervasive development- and tissue-specific homeolog expression partitioning in newly formed inter- subspecific rice segmental allotetraploids，BMC GENOMICS，2018年
2. Genetic and epigenetic divergence of duplicate genes in two legume species，PLANT CELL ENVIRON，2018年
3. Horizontal Transfer of Non-LTR Retrotransposons from Arthropods to Flowering Plants，MOL BIOL EVOL，2018年
4. Segmental allotetraploidy generates extensive homoeologous expression rewiring and phenotypic diversity at the population level in rice，MOL ECOL，2017年
5. Gene-body CG methylation and divergent expression of duplicate genes in rice，SCIENTIFIC REPORTS，2017年
6. DNA methylation affects gene alternative splicing in plants: an example from rice，MOLECULAR PLANT，2016年
7. Transcriptome shock in an interspecific F1 triploid hybrid of Oryza revealed by RNA sequencing，J INTEGR PLANT BIOL，2016年
8. Nonuniform gene expression pattern detected along the longitudinal axis in the matured rice leaf，SCIENTIFIC REPORTS ，2015年
9. DNA Methylation Changes Induced in Rice by Exposure to High Concentrations of the Nitric Oxide Modulator, Sodium Nitroprusside，PLANT MOL BIOL REP，2015年
10. Mutation of a major CG methylase in rice causes genome-wide hypomethylation,dysregulated genome expression,and seedling lethality，P NATL ACAD SCI USA，2014年
11. Evolution of the BBAA Component of Bread Wheat during Its History at the Allohexaploid Level，PLANT CELL，2014年
12. Tissue Culture-Induced Heritable Genomic Variation in Rice, and Their Phenotypic Implications ，PLoS ONE ，2014年
13. Genome-Wide Disruption of Gene Expression in Allopolyploids but Not Hybrids of Rice Subspecies，MOL BIOL EVOL，2014年
14. Intrinsic karyotype stability and gene copy number variations may have laid the foundation for tetraploid wheat formation，P NATL ACAD SCI USA，2013年
15. Genomewide Variation in an Introgression Line of Rice-Zizania Revealed by Whole-Genome re-Sequencing，PLoS ONE ，2013年
16. Tissue culture-induced genetic and epigenetic alterations in rice pure-lines, F1 hybrids and polyploids，BMC PLANT BIOL，2013年
17. Persistent whole-chromosome aneuploidy is generally associated with nascent allohexaploid wheat，P NATL ACAD SCI USA，2013年
18. Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres，NATURE，2012年
19. Transgenerational Inheritance of Modified DNA Methylation Patterns and Enhanced Tolerance Induced by Heavy Metal Stress in Rice (Oryza sativa L.)，PLoS ONE ，2012年
20. Regulation of ion homeostasis in rice subjected to salt and alkali stresses，AUSTRALIAN JOURNAL OF CROP SCIENCE，2012年
21. Global transgenerational gene expression dynamics in two newly synthesized allohexaploid wheat (Triticum aestivum) lines，BMC BIOL，2012年
22. Induced Pib Expression and Resistance to Magnaporthe grisea are Compromised by Cytosine Demethylation at Critical Promoter Regions in Rice，J INTEGR PLANT BIOL，2011年
专利：
诱导渐渗系水稻RZ1和RZ2中的Homebox基因发生甲基化升高的方法 2014-10-29