王飞
姓名： 王飞

职称： 副教授
最高学位： 博士
Email：
工作地点： 生命科学楼361室
研究方向： 肿瘤及干细胞的表观遗传学调控机制
教育经历： 2001-2005 吉林大学生命科学学院 生物科学专业 本科
2005-2010 吉林大学生命科学学院 生物化学与分子生物学专业 博士
2008-2010 美国路易斯安纳州立大学健康科学中心药理、毒理及神经生物学系 联合培养博士
工作经历： 2011-2016 吉林大学生命科学学院 讲师
2016至今 吉林大学生命科学学院 副教授

研究成果： 1.Jiang D, Wang L, Zhao T, Zhang Z, Zhang R, Jin J, Cai Y and Wang F: Restoration of the tumor-suppressor function to mutant p53 by Ganoderma lucidum polysaccharides in colorectal cancer cells. Oncol. Rep. 37: 594-600, 2017.
2.Wu D, Zhao L, Feng Z, Yu C, Ding J, Wang L, Wang F, Liu D, Zhu H, Xing F, Conaway JW, Conaway RC, Cai Y and Jin J: O-Linked N-acetylglucosamine transferase 1 regulates global histone H4 acetylation via stabilization of the nonspecific lethal protein NSL3. J. Biol. Chem. 292: 10014-10025, 2017.
3.Wang F, Zhao J, Liu D, Zhao T, Lu Z, Zhu L, Cao L, Yang J, Jin J and Cai Y: Capsaicin reactivates hMOF in gastric cancer cells and induces cell growth inhibition. Cancer Biol. Ther. 17: 1117-1125, 2016.
4.Su J, Sui Y, Ding J, Li F, Shen S, Yang Y, Lu Z, Wang F, Cao L, Liu X, Jin J and Cai Y: Human INO80/YY1 chromatin remodeling complex transcriptionally regulates the BRCA2- and CDKN1A-interacting protein (BCCIP) in cells. Protein & cell 7: 749-760, 2016.
5.Su J, Wang F, Cai Y and Jin J: The Functional Analysis of Histone Acetyltransferase MOF in Tumorigenesis. International journal of molecular sciences 172016.
6.Wang J, Guan J, Lu Z, Jin J, Cai Y, Wang C and Wang F: Clinical and tumor significance of tropomyosin-1 expression levels in renal cell carcinoma. Oncol. Rep. 33: 1326-1334, 2015.
7.Zhu L, Yang J, Zhao L, Yu X, Wang L, Wang F, Cai Y and Jin J: Expression of hMOF, but not HDAC4, is responsible for the global histone H4K16 acetylation in gastric carcinoma. Int. J. Oncol. 46: 2535-2545, 2015.
8.Liu D, Wu D, Zhao L, Yang Y, Ding J, Dong L, Hu L, Wang F, Zhao X, Cai Y and Jin J: Arsenic Trioxide Reduces Global Histone H4 Acetylation at Lysine 16 through Direct Binding to Histone Acetyltransferase hMOF in Human Cells. PLoS One 10: e**, 2015.
9.Cao L, Ding J, Dong L, Zhao J, Su J, Wang L, Sui Y, Zhao T, Wang F, Jin J and Cai Y: Negative Regulation of p21Waf1/Cip1 by Human INO80 Chromatin Remodeling Complex Is Implicated in Cell Cycle Phase G2/M Arrest and Abnormal Chromosome Stability. PLoS One 10: e**, 2015.
10.丁健, 王飞, 金景姬 and 蔡勇: 表观遗传之染色质重塑. Progress in Biochemistry and Biophysics 42: 994-1002, 2015.
11.Cao L, Zhu L, Yang J, Su J, Ni J, Du Y, Liu D, Wang Y, Wang F, Jin J and Cai Y: Correlation of low expression of hMOF with clinicopathological features of colorectal carcinoma, gastric cancer and renal cell carcinoma. Int. J. Oncol. 44: 1207-1214, 2014.
12.Zhao X, Su J, Wang F, Liu D, Ding J, Yang Y, Conaway JW, Conaway RC, Cao L, Wu D, Wu M, Cai Y and Jin J: Crosstalk between NSL histone acetyltransferase and MLL/SET complexes: NSL complex functions in promoting histone H3K4 di-methylation activity by MLL/SET complexes. PLoS Genet. 9: e**, 2013.
13.Wang F, Liu J, Robbins D, Morris K, Sit A, Liu YY and Zhao Y: Mutant p53 exhibits trivial effects on mitochondrial functions which can be reactivated by ellipticine in lymphoma cells. Apoptosis : an international journal on programmed cell death 16: 301-310, 2011.