一 基本信息：
姓 名 刘殿峰
职 称 教授博士生导师
所在部门 动物科学学院
研究方向 人类疾病动物模型与分子病因学
实验动物种子资源保存与利用
现担任中国实验动物学会动物环境控制与节能专业委员会委员
东三省实验动物专家委员会委员
办公电话**
电子邮件ccldf@163.com
二学习与工作经历：
1981-1985沈阳农业大学畜牧专业农学学士
1996.1-1996.12日本东海大学健康科学部研修
2000-2003农牧大学动物学理学硕士
2003-2006吉林大学基础兽医学农学博士
2006-至今吉林大学动物科学学院教授/系主任
三主要教学工作
承担本科生《实验动物学》《实验动物生产学》与实习等课程；研究生《实验动物学进展》《实验动物质量检测》等课程。
四主要科研工作
国家自然基金项目“GLP-2对大鼠炎症性肠病的作用及机制”（项目批准号： **）， 2013-2016主持人79万元
吉林省自然科学基金项目“GLP-2与大鼠IBD的关系及相关机制研究”（项目批准号：），2012 - 2014主持人5万元
吉林省科技项目“神经炎症介导的帕金森病模型的建立及其在药物开发中的应用”（项目批准号：TC），2017-2019主持人20万元
吉林省科技项目“杜鹃素对LPS诱导的帕金森病模型的神经保护作用及其机制”
主持人10万元
吉林省自然科学基金项目“析小鼠癌症模型中H19与VEGF表达和甲基化模式分析”（JC），2018-2020主持人15万元
国家自然基金项目“HCA2在帕金森病小鼠模型中的神经保护作用及其机制”（项目批准号：**）2018-2021主持人62万元
五科研成果
1. Dewei He , Bingxu Huang , Shoupeng Fu , Yuhang Li , Xin Ran, Yandan Liu, Guangxin Chen, Juxiong Liu * and Dianfeng Liu *.Tubeimoside I Protects Dopaminergic Neurons Against In?ammation-Mediated Damage in Lipopolysaccharide (LPS)-Evoked Model of Parkinson’s Disease in Rats. Int. J. Mol. Sci. 2018, 19(8), 2242.
2. YAN, X., LIU, D. F., ZHANG, X. Y., LIU, D., XU, S. Y., CHEN, G. X., HUANG, B. X., REN, W. Z., WANG, W., FU, S. P. & LIU, J. X. Vanillin Protects Dopaminergic Neurons against Inflammation-Mediated Cell Death by Inhibiting ERK1/2, P38 and the NF-kappaB Signaling Pathway. Int J Mol Sci, 2017. 18(2).
3. HAO, Y., WANG, G., LIN, C., LI, D., JI, Z., GAO, F., LI, Z., LIU, D. & WANG, D. Valproic Acid Induces Decreased Expression of H19 Promoting Cell Apoptosis in A549 Cells. DNA Cell Biol, 2017. 36(6): p. 428-435.
4. WANG, D., WANG, G., YANG, H., LIU, H., LI, C., LI, X., LIN, C., SONG, Y., LI, Z. & LIU, D. DNA methylation modulates H19 and IGF2 expression in porcine female eye. Genet Mol Biol, 2017. 40(1): p. 153-159.
5. Bingxu Huang,aDewei He,aGuangxin Chen,aXin Ran,aWenjin Guo,aXingchi Kan,aWei Wang,aDianfeng Liu,aShoupeng Fu*aandJuxiong Liu*a. α-Cyperone inhibits LPS-induced inflammation in BV-2 cells through activation of Akt/Nrf2/HO-1 and suppression of the NF-κB pathway. Food Funct., Food Funct., 2018, 9, 2735–2743.
6. Guangxin Chen, Juxiong Liu, Liqiang Jiang, Xin Ran, Dewei He, Yuhang Li, Bingxu Huang, Wei Wang, Dianfeng Liu, and Shoupeng Fu*. Peiminine Protects Dopaminergic Neurons from Inflammation-Induced Cell Death by Inhibiting the ERK1/2 and NF-κB Signalling Pathways. Int J Mol Sci. 2018 Mar; 19(3): 821.
7. Bingxu Huang, Juxiong Liu, Chen Ju, Dongxue Yang, Guangxin Chen, Shiyao Xu, Yalong Zeng, Xuan Yan, Wei Wang, Dianfeng Liu, and Shoupeng Fu*. Licochalcone A Prevents the Loss of Dopaminergic Neurons by Inhibiting Microglial Activation in Lipopolysaccharide (LPS)-Induced Parkinson’s Disease Models. Int J Mol Sci. 2017 Oct; 18(10): 2043.
8. Li Nan#, Liu Bo-Wen#, Ren Wen-Zhi#, Liu Ju-Xiong#, Li Su-Nan#, Fu Shou-Peng, Zeng Ya-Long, Xu Shi-Yao, Yan Xuan, Gao Ying-Jie, Liu Dian-Feng, Wang Wei*. GLP-2 Attenuates LPS-Induced Inflammation in BV-2 Cells by Inhibiting ERK1/2, JNK1/2 and NF-κB Signaling Pathways. International journal of molecular sciences. 2016;17(2):190. (SCI, IF=3.257)
9.Du XY1, Yi S2, Huo XY1, Wang C1, Liu DF2, Ren WZ2, Chen ZW3.Selecting representative microsatellite loci for genetic monitoring and analyzing genetic structure of an outbred population of orange tabby cats in China. Genet Mol Res, 2015. 14(1): p. 1788-97.
10. Lv Qing-Kang#, Liu Ju-Xiong#, Li Su-Nan#, Gao Ying-Jie#, Lv Yan#, Xu Zi-Peng, Huang Bing-Xu, Xu Shi-Yao, Yang Dong-Xue, Zeng Ya-Long, Liu Dian-Feng, Wang Wei *. Mycophenolate Mofetil Modulates Differentiation of Th1/Th2 and the Secretion of Cytokines in an Active Crohn’s Disease Mouse Model. International journal of molecular sciences, 2015; 16(11):26654-66. (SCI, IF=3.257)
11. Xie S1, Liu B, Fu S, Wang W, Yin Y, Li N, Chen W, Liu J, Liu D.GLP-2 suppresses LPS-induced inflammation in macrophages by inhibiting ERK phosphorylation and NF-kappaB activation. Cell Physiol Biochem, 2014. 34(2): p. 590-602.
12. Xie Shan-Shan#, Liu Bing-Run#, Fu Shou-Peng#, Wang Wei#, Yin Yun-Hou#, Li Nan, Chen Wei, Liu Ju-Xiong*, Liu Dian-Feng*. GLP-2 Suppresses LPS-Induced Inflammation in Macrophages by Inhibiting ERK Phosphorylation and NF-κB Activation. Cellular physiology and biochemistry. 2014; 34(2): 590-602. (SCI, IF=4.652)
13.Na Chen1,?, Dianfeng Liu2,?, Lanan Wassy Soromou1, Jingjing Sun1, Weiting Zhong1, Weixiao Guo1, Meixia Huo1, Hongyu Li1, Shuang Guan1, Zhenwen Chen3 and Haihua Feng1,*. Paeonol suppresses lipopolysaccharide-induced inflammatory cytokines in macrophage cells and protects mice from lethal endotoxin shock.Fundam Clin Pharmacol. 2014. 6;28(3):268-76.
14.Xiao Chu 1 *, Lanxiang Jiang 2 *, Miaomiao Wei 1, Xiaofeng Yang 1, Mingfeng Guan 1, Xianxing Xie 1, Jingyuan Wei 1, 3, Dianfeng Liu 4 *, and Dacheng Wang 1 *. Attenuation of allergic airway inflammation in a murine model of asthma by Licochalcone A. Immunopharmacol Immunotoxicol. 2013.10;35(6):653-61
15.B. Guoa, X._M. Zhanga, S._J. Lib, X._C. Tiana, S._T. Wanga, D._D. Lia, D._F. Liua, and Z._P. Yuea. Expression and Regulation of Ang_2 in Murine Ovaries during Sexual Maturation and Development of Corpus Luteum1 . Molecular Biology, 2012, Vol. 46, No. 6, pp. 804–810.
六奖励与荣誉
参与吉林省科技进步二、三等奖各一项
2014年获吉林大学教书育人先进个人