课题组简介

本课题组研究方向为天然产物和药物合成、过渡金属催化和不对称催化反应方法学研究。已在Chem. Soc. Rev.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Nat. Commun.、Adv. Mater.、iScience、Chem. Commun.、Org. Lett.、Chem. Eur. J.、Adv. Synth. Catal.等发表论文70余篇，被包括Science、Nature在内的国际知名刊物引用2200余次，被Nat. Rev. Chem.、Chem. Rev.、Chem. Soc. Rev.、Coord. Chem. Rev.、 Synfacts等进行图文评论或亮点工作介绍50余次，单篇最高引用500余次。

韩福社：男，中科院长春应化所研究员

博士生导师，中科院“百人计划”。
教育经历：

1996年9月至1999年9月：中科院长春应化所，博士；

1993年9月至1996年7月：大连理工大学，硕士；

1989年9月至1993年7月：重庆大学，学士
工作经历：

2008年8月至今：中科院长春应用化学研究所，研究员；

2006年4月至2008年7月：日本国立物质材料研究机构，博士研究员；

2003年4月至2006年3月：东京大学药学部，科学技振兴机构（JST）研究员；

2001年8月至2003年3月：日本爱媛大学工学部，博士后 ；

1999年10月至2001年7月：中科院上海有机所生命有机室，博士后
项目情况：

承担中科院“百人计划”、国家自然基金面上项目、省院科技合作高技术产业化专项资金、吉林省重点科技攻关项目及企业合作项目等30余项。


机理学习
Home>机理学习
2019年12月

    Enantioselective Total synthesis of Lyconadins A-E through A palladium-catalyzed Heck-type reaction
    Total synthesis of (+)-6-epi-Ophiobolin A
    Total Synthesis and Structural Revision of a Harziane Diterpenoid
    Synthesis of (−)-Mitrephorone A via a Bioinspired Late Stage C−H
    Mechanism-exercises-December-1
    Mechanism-exercises-December-2
    Mechanism-exercises-December-3
    Mechanism-exercises-December-4

2019年11月

    A Ten-step Total Synthesis of Speradine C
    Mechanism-exercises-november-1
    Mechanism-exercises-november-2
    Mechanism-exercises-november-3
    Total Synthesis and Stereochemical Assignment of Streptide

2019年10月

    Total Synthesis of Viridin and Viridiol
    Mechanism-exercises-october-1
    Mechanism-exercises-october-2

2019年9月

    Total Synthesis of Isomalabaricane Triterpenoids
    Mechanism-exercises-september-1
    Mechanism-exercises-september-2
    Total Synthesis of Himeradine A

2019年8月

    Enantioselective Total Synthesis of (−)-Caldaphnidine O via a Radical Cyclization Cascade
    Mechanism-exercises-August-1
    Mechanism-exercises-August-2
    Total Synthesis and Structure Rervision of (-)-IllisimoninA, a Neuroprotective Sesquiterpenoid from the Fruits of Illicium simonsii

2019年7月

    Asymmetric Total Synthesis of Arcutinidine, Arcutinine, and Arcutine
    Mechanism exercises-July-3
    Mechanism exercises-July-2
    Mechanism exercises-July-1
    Total Synthesis of (+)-Granatumine A

2019年6月

    Mechanism exercises-June-3
    Mechanism exercises-June-1
    Mechanism exercises-June-2
    Convergent Total Synthesis of Pricipinol D a Rearranged Kaurane Diterpenoid
    Enantioselective Total Synthesis of Pseudopteroxazole and
    Synthesis of (+)-Darwinolide, a Biofilm-Penetrating Anti-MRSA Agent
    Total Synthesis of (-)-Ambigunine P

2019年5月

    Mechanism exercises-May-1
    Mechanism exercises-May-2
    Calyciphylline B-type Alkaloids Total syntheses of Daphlongamine H and Isodaphongamine H
    Quaternary-centre-guided synthesis of complex polycyclic terpenes

2019年4月

    Mechanism exercises-April-2
    Mechanism exercises-April-1
    Total Synthesis of Daphenylline
    Enantioselective Total Synthesis of (-)-Arcutinine

2019年3月

    Mechanism exercises-March-5
    Mechanism exercises-March-4
    Mechanism exercises-March-3
    Mechanism exercises-March-2
    Mechanism exercises-March-1
    Total synthesis of Indoxamycins A and B
    Step Total Synthesis of Atropurpuran
    Enantioselective Synthesis of Azamerone


科研成果
Home>科研成果
代表性论文：

1、“Transition-Metal-Catalyzed Suzuki-Miyaura Cross-Coupling Reactions: A Remarkable Advance from Palladium to Nickel Catalysts”, F. Han,* Chem. Soc. Rev., 2013, 42, 5270. (Invited review, top 1% of highly cited authors in 2014).

2、“Enantioselective Total Synthesis and Configuration Assignment of (+)-Tronocarpine Enabled by an Asymmetric Michael/Aldol Reaction”, Dong-Xing Tan, Jie Zhou, Chao-You Liu, Fu-She Han,* Angew. Chem. Int. Ed., 2020, 59, 3834-3839. (Frontispiece Cover). (D.-X. Tan and J. Zhou contributed equally).

3、“Total Synthesis of Cyrneines A, B, and Glaucopine C”, G.-J. Wu, Y.-H. Zhang, D.-X. Tan, F.-S. Han,* Nat. Commun., 2018, 9, 2148. (Highlighted by SYNFACTS, 2018, 14(08), 0787).

4、“Palladium-Catalyzed Enantioselective Synthesis of P-Stereogenic Phosphinamides via Desymmetric C–H Arylation”, Z.-J. Du,# J. Guan,# G.-J. Wu, P. Xu, L.-X. Gao, F.-S. Han,* J. Am. Chem. Soc., 2015, 137, 632. (Highlighted by SYNFACTS, 2015, 11(4), 0404)

5、“Metallo-Supramolecular Polyelectrolytes Self-assembled from Various Pyridine Ring Substituted Bis-terpyridines and Metal Ions: Photophysical, Electrochemical and Electrochromic Properties” F. Han, M. Higuchi, D. G. Kurth, J. Am. Chem. Soc., 2008, 130, 2073.

6、“Metallo-Supramolecular Polymers Based on Functionalized Bis-terpyridines as Novel Electrochromic Materials” F. Han, M. Higuchi, D. G. Kurth, Adv. Mater., 2007, 19, 3928.

7、“Pd-Catalyzed aerobic oxidative Heck cross-coupling for the straightforward construction of indole d-lactams”, J. Zhang, F.-S. Han,* iScience, 2019, 17, 256.

8、“Efficient Synthesis of Cyclic P-Stereogenic Phosphinamide from Acyclic Chiral Precursors via Radical Oxidative Intramolecular Aryl C–H Phosphinamidation”, Y.-H. Chen, X.-L. Qin, F.-S. Han,* Chem. Commun., 2017, 53, 5826.

9、 “Organocatalytic Asymmetric Reaction of Indol-2-yl Carbinols with Enamides: Synthesis of Chiral 2-Indole-Substituted 1,1-Diarylalkanes”, C.-Y. Liu, F.-S. Han,* Chem. Commun., 2015, 51, 11844.

10、“A Total Synthesis of (–)-Hamigeran B and (–)-4-Bromohamigeran B”, B-C.  Cao,#        G.-J. Wu,# F. Yu, Y.-P. He*, F.-S. Han,* Org. Lett., 2018, 20, 3687.

11、“Synthetic Study Toward the Misassigned (±)-Tronoharine”, X. Zhong, Y. Li, J. Zhang, F.-S. Han,* Org. Lett., 2015, 17, 720.
全部论文：

79、“Enantioselective Total Synthesis and Configuration Assignment of (+)-Tronocarpine Enabled by an Asymmetric Michael/Aldol Reaction”, Dong-Xing Tan, Jie Zhou, Chao-You Liu, Fu-She Han,* Angew. Chem. Int. Ed., 2020, 59, 3834-3839. (Frontispiece Cover). (D.-X. Tan and J. Zhou contributed equally).

78、“A Total Synthesis of (±)Leuconodines D and E”, J. Zhang, F.-S. Han,* J. Org. Chem., 2019, 84, 13890-13896.(The top 20 most download articles in September and October, 2019)

77、“Pd-Catalyzed aerobic oxidative Heck cross-coupling for the straightforward construction of indole d-lactams”, J. Zhang, F.-S. Han,* iScience, 2019, 17, 256.

76、“Synthetic Studies on Enantioselective Total Synthesis of Cyathane Diterpenoids: Cyrneines A and B, Glaucopine C, and (+)-Allocyathin B2”, G.-J. Wu,# Y.-H. Zhang,# D.-X. Tan, L. He, B.-C. Cao, Y.-P. He, F.-S. Han,* J. Org. Chem., 2019, 84, 3223. (The top 20 most download articles in March and April, 2019)

75、“Synthesis of P-Stereogenic Diarylphosphinamides as Novel Inhibitors of Melanoma”, X. Tang, Z.-J. Du, G.-J. Wu, F.-S. Han,* Chem. Res. Chin. Univ., 2019, 35, 812-816.

74、“A Total Synthesis of (–)-Hamigeran B and (–)-4-Bromohamigeran B”, B-C. Cao,# G.-J. Wu,# F. Yu, Y.-P. He*, F.-S. Han,* Org. Lett., 2018, 20, 3687.

73、“Total Synthesis of Cyrneines A, B, and Glaucopine C”, G.-J. Wu, Y.-H. Zhang, D.-X. Tan, F.-S. Han,* Nat. Commun., 2018, 9, 2148, DOI: 10.1038/s41467-018-04480-6 (Highlighted by SYNFACTS, 2018, 14(08), 0787).

72、“A Facile Synthesis of Chiral Phosphinoaryloxazolines”, B. Cao, G. Wu,* Y. He,* F.-S. Han, Chin. J. Appl. Chem., 2018, 35, 189.

71、“A Convenient Synthesis of Indole and 1,4-Dihydropyridine Hybrid Macrocycles by Dimerization of [2-(1H-Indol-3-yl)ethyl]pyridinium Salts”, G. Ling, J. Zhang, R.-Z. Zhang, F.-S. Han,* Heterocycles, 2018, 96, 67.

70、“CuCl2/8-Hydroxyquinoline-Catalyzed a-Arylation of Diethyl Malonate with Aryl Bromides”, J.-Q. Yang, G.-J. Wu*, Y.-P. He* , F.-S. Han, Chem. Res. Chin. Univ., 2018, 34, 727.

69、“Efficient Synthesis of Cyclic P-Stereogenic Phosphinamide from Acyclic Chiral Precursors via Radical Oxidative Intramolecular Aryl C–H Phosphinamidation”, Y.-H. Chen, X.-L. Qin, F.-S. Han,* Chem. Commun., 2017, 53, 5826.

68、“A Thermoregulated Phase-Separable Chiral Pt Nanocatalyst for Recyclable Asymmetric Hydrogenation of α-Ketoesters”, X. Xue, Y. Wang,* F.-S. Han,* Chem. Commun., 2017, 53, 3346.

67、“Pd-Catalyzed Enantioselective C–H Arylation of Phosphinamides with Boronic Acids for Synthesis of P-Stereogenic Compounds”, Y.-H. Chen, X.-L. Qin, J. Guan, Z.-J. Du, F.-S. Han,* Tetrahedron: Asymmetry, 2017, 28, 522.

66、“Copper-Catalyzed Reductive N-Alkylation of Amides with N-Tosylhydrazones Derived from Ketones”, P. Xu, F.-L. Qi, F.-S. Han,* Y.-H. Wang*, Chem. Asian J., 2016, 11, 2030.

65、“Copper(I)-Catalyzed Amidation of Aldehydes and Amides Mediated by N-tosylhydrazones”, P. Xu, F.-S. Han,* Y.-H. Wang,* Adv. Synth. Catal., 2015, 357, 3441.

64、“Palladacycles Derived from Arylphosphinamides for Mild Suzuki-Miyaura Cross-Couplings”, G.-J. Wu, F.-S. Han,* Y.-L. Zhao,* RSC Adv., 2015, 5, 69776.

63、“Organocatalytic Asymmetric Reaction of Indol-2-yl Carbinols with Enamides: Synthesis of Chiral 2-Indole-Substituted 1,1-Diarylalkanes”, C.-Y. Liu, F.-S. Han,* Chem. Commun., 2015, 51, 11844.

62、“A Straightforward Synthesis of Alkyl 1H-Tetrazol-5-yl Thioethers via a One-pot Reaction of Aldehydes and 1H-tetrazole-5-thiols Mediated by N-tosylhydrazones”, L.-L. Li, L.-X. Gao, F.-S. Han,* RSC Adv., 2015, 5, 29996.

61、“Synthetic Study Toward the Misassigned (±)-Tronoharine”, X. Zhong, Y. Li, J. Zhang, F.-S. Han,* Org. Lett., 2015, 17, 720.

60、 “Palladium-Catalyzed Enantioselective Synthesis of P-Stereogenic Phosphinamides via Desymmetric C–H Arylation”, Z.-J. Du,# J. Guan,# G.-J. Wu, P. Xu, L.-X. Gao, F.-S. Han,* J. Am. Chem. Soc., 2015, 137, 632. (Highlighted by SYNFACTS, 2015, 11(4), 0404)

59、 “The Development of a Complementary Pathway for the Synthesis of Aliskiren”, L.-L. Li, J.-Y. Ding, L.-X. Gao, F.-S. Han,* Org. Biomol. Chem., 2015, 13, 1133.

58、“A study in indol-2-yl carbinol chemistry and the application for the total synthesis of Mersicarpine”, X. Zhong, S. Qi, Y. Li, J. Zhang, F.-S. Han,* Tetrahedron, 2015, 71, 3734 (Invited article)

57、“The determination of the absolute configuration of chiral                                       2,3′-diindolylarylmethanes assisted by NMR spectroscopy”, S. Qi, C.-Q. Kang, F.-S. Han,* Magn. Reson. Chem., 2015, 53, 181.

56、“Formal [3+3] Cyclization of Indol-2-yl Carbinol with Aza-Diene and the Subsequent Oxidative Ring Expansion Reaction for the Synthesis of Indole Azepinones”, X. Zhong, Y. Li, W.-X. Zhang, J. Zhang, S.-X. Wang, F.-S. Han,* Chem. Commun., 2014, 50, 11181.

55、“Chiral Phosphoramide-Catalyzed Enantioselective Synthesis of 2,3’-Diindoylarylmethanes from Indol-2-yl Carbinol and Indole”, S. Qi, C.-Y. Liu, J.-Y. Ding, F.-S. Han,* Chem. Commun., 2014, 50, 8605.

54、“Palladium-Catalyzed Silver-Mediated α-Arylation of Acetic acid: A New Approach for the α-Arylation of Carbonyl Compounds”, G.-J. Wu, J. Guan, F.-S. Han,* Y.-L. Zhao,* ChemCatChem, 2014, 6, 1589.

53、“Cu-Mediated Direct Aryl C–H Halogenation: a Strategy to Control Mono- and Di-Selectivity”, Z.-J. Du, L.-X. Gao, Y.-J. Lin, F.-S. Han,* ChemCatChem, 2014, 6, 123–126.

52、“Pd(II)-Catalyzed Mild C–H ortho Arylation and Intramolecular Amination Oriented by Phosphinamide Group”, J. Guan, G.-J.Wu, F.-S. Han,* Chem. Eur. J., 2014, 20, 3301.

51、“The Development of Copper-Catalyzed Aerobic Oxidative Coupling of H-Tetrazoles with Boronic Acids and an Insight into the Reaction Mechanism”, C.-Y. Liu, Y. Li, J.-Y. Ding, D.-W. Dong, F.-S. Han,* Chem. Eur. J., 2014, 20, 2373–2381.

50、“Design and Synthesis of Polyoxazole-based Macrocycles Tethered with a Phosphonate Group”, F.-L. Qi, L.-X. Gao, F.-S. Han,* Chin. J. Chem., 2014, 32, 585. (Cover picture)

49、 “Design and Synthesis of Macrocyclic Polyoxazoles”, F.-L. Qi, L.-X. Gao, F.-S. Han,* Chem. Res. Chin. Univ., 2014, 30, 587.

48、“Divergent Synthesis of 2,3-Dihydro-1H-pyrrole, 3-Alkyl-1H-pyrroles and 3-alkenyl-1H-pyrroles from 2,4-Pentadienenitriles and Isocyanide”, X. Xin, X. Liu, D. Zhang, R. Zhang, Y. Liang,* F.-S. Han, D. Dong,* Org. Biomol. Chem., 2014, 12, 5477.

47、“Pd(II)-Catalyzed C–H arylation of Aryl phosphonic Acid Derivatives and the Derivatization Reaction of the Coupled Products”, J. Guan, G. Wu, F.-S. Han,* Chin. J. Appl. Chem., 2014, 31, 1280.

46、“The Crystallographic Observation of Mesitylene-Mesitylene and Mesitylene-CH2Cl2-Mesitylene Adducts Trapped in an Irregular Cavity”, Y. Chen, L. Ma, Z. Bian, R.-Z. Jin, C.-Q. Kang, Z.-J. Li, X. Gao, F.-S. Han, X.-P. Qiu, L.-X. Gao, CrysEngComm, 2014, 37, 8652.

45、“Copper-Mediated Direct Aryl C–H Cyanation with Azobisisobutyro-nitrile via a Free-radical Pathway”, H. Xu, P.-T. Liu, Y.-H. Li, F.-S. Han,* Org. Lett., 2013, 15, 3354.

44、“Transition-Metal-Catalyzed Suzuki-Miyaura Cross-Coupling Reactions: A Remarkable Advance from Palladium to Nickel Catalysts”, F. Han,* Chem. Soc. Rev., 2013, 42, 5270. (Invited review, top 1% of highly cited authors in 2014)

43、“Iron-Catalyzed Direct Synthesis of Densely Substituted Benzofurans and Naphthopyrans from Phenolic Compounds and Propargylic Alcohols” F.-Q. Yuan, F. Han*, Adv. Synth. Catal., 2013, 355, 537.

42、“Cu2O-Mediated Room Temperature Cyanation of Aryl Boronic Acids/Esters and TMSCN”, Y. Ye, Y.-H. Wang, P.-T. Liu, F. Han*, Chin. J. Org. Chem., 2013, 31, 27. (Invited paper)

41、“Al-Catalyzed Facile Construction of Quaternary C–C Bonds via the Allylic Substitution of tertiary Alcohols: A Concise Formal Synthesis of (±)-Mersicarpine”, X. Zhong, Y. Li, F. Han*, Chem. Eur. J., 2012, 18, 9784.

40、“Ni-Catalyzed Construction of C–P Bond from Electron-deficient Phenols via the in situ Aryl C–O Activation by PyBroP”, Y.-L. Zhao, G.-J. Wu, F. Han*, Chem. Commun., 2012, 48, 5868.

39、“Ni(dppp)-Catalyzed Cross-coupling of Aryl Halides with Dialkylphosphite, Diphenylphosphine oxide, and Diphenylphosphine”, Y.-L. Zhao, G.-J. Wu, Y. Li, L.-X. Gao, F. Han*, Chem. Eur. J., 2012, 18, 9622.

38、“Synthesis of Densely Substituted a,b,g,d-Dienones via the PdII-Catalyzed Allylation, H-Migration, and Aerobic Oxidative d-Hydride Elimination Cascade”, F.-Q. Yuan, F. Han*, Org. Lett., 2012, 14, 1218.

37、“Efficient Synthesis of 2,5-Disubstituted Tetrazoles via the Cu2O-Catalyzed Aerobic Oxidative Direct Cross-coupling of N-H Free Tetrazoles with Boronic Acids”, Y. Li, L.-X. Gao, F. Han*, Chem. Commun., 2012, 48, 2719.

36、 “An Efficient Suzuki-Miyaura Coupling of Aryl Sulfamates and Boronic Acids Catalyzed by NiCl2(dppp)”, G.-J. Chen, F. Han*, Eur. J. Org. Chem., 2012, 3575.

35、“A simple and efficient method for the allylation of heteroarenes catalyzed by PdCl2”, F.-Q. Yuan, F.-Y. Sun, F. Han*, Tetrahedron, 2012, 68, 6837.

34、“Review of Allylation and Benzylation of Heteroarenes”, F.-Q. Yuan, F.-Y. Sun, F. Han,* Chin. J. Appl. Chem., 2012, 29, 1343.

33、“PdCl2(dppf)-Catalyzed in situ Coupling of 2-Hydroxypyridines with Aryl Boronic Acids Mediated by PyBroP and the one-pot Chemo- and Regioselective Construction of two Distinct Aryl-Aryl Bonds”, S.-M. Li, J. Huang, G.-J. Chen, F. Han*, Chem. Commun., 2011, 47, 12840.

32、“PdCl2-Catalyzed Efficient Allylation and Benzylation of Heteroarenes under Ligand, Base/Acid, and Additive-Free Conditions”, F.-Q. Yuan, L.-X. Gao, F. Han*, Chem. Commun., 2011, 47, 5289.

31、“Ni-Catalyzed Cross-Coupling of Phenols and Aryl Boronic Acids via an in situ Phenol Activation Mediated by PyBrOP”, G. J. Chen, J. Huang, L. X. Gao, F. Han*, Chem. Eur. J., 2011, 17, 4038.

30、 “A Highly Practical and Reliable Nickel Catalyst for Suzuki-Miyaura Coupling of Aryl Halides” Y.-L. Zhao, Y. Li, S.-M. Li, Y.-G. Zhou, F.-Y. Sun, L.-X. Gao, F.-S. Han*, Adv. Synth. Catal., 2011, 353, 1543.

29、 “Highly Efficient Suzuki-Miyaura Coupling of Aryl Tosylates and Mesylates Catalyzed by Stable, Cost-effective [1,3-Bis(diphenylphosphino)propane]nickel(II) Chloride {Ni(dppp)Cl2} with only 1 mol % Loading”, H. Gao, Y. Li, Y. G. Zhou, F. Han,* Y. J. Lin*, Adv. Synth. Catal., 2011, 353, 309.

28、“An Organogel Formed from a cyclic b-aminoalcohol”, C. Kang, Z. Bian, Y. He, F. Han, X. Qiu, L.-X. Gao, Chem. Commun., 2011, 47, 10746.

27、“Reliable and Diverse Synthesis of Aryl Azides via Copper-Catalyzed Coupling of Boronic Acids/Esters with TMSN3”, Y. Li, L. X. Gao, F. Han*, Chem. Eur. J., 2010, 16, 7969.

26、“Aryl Phosphoramides: Useful Electrophiles for Suzuki-Miyaura Coupling Catalyzed by NiCl2/dppp System”, Y. L. Zhao, Y. Li, Y. Li, L. X. Gao, F. Han*, Chem. Eur. J., 2010, 16, 4991.

25、“Asymmetric Michael addition of aldehydes to nitroolefins catalyzed by L-prolinamide derivatives using phenols as co-catalysts”, Y. Cheng, Z. Bian, Y. He, F. Han, et al, Tetrahedron Asymmetry, 2009, 20, 1753.

24、“Synthesis of p-conjugated Pyridine Ring Functionalized Bis-terpyridines with Efficient Green, Blue and Purple Emission” F. Han, M. Higuchi, D. G. Kurth, Tetrahedron, 2008, 64, 9108.

23、“Luminescence Properties of Metallo-supramolecular Coordination Polymers Assembled from Pyridine Ring Functionalized Ditopic Bis-terpyridine and Ru(II) ions” F. Han, M. Higuchi, T. Ikeda, Y. Negishi, T. Tsukuda, D. G. Kurth, J. Mater. Chem., 2008, 18, 4555.

22、“Metallo-Supramolecular Polyelectrolytes Self-assembled from Various Pyridine Ring Substituted Bis-terpyridines and Metal Ions: Photophysical, Electrochemical and Electrochromic Properties” F. Han, M. Higuchi, D. G. Kurth, J. Am. Chem. Soc., 2008, 130, 2073.

21、“Metallo-Supramolecular Polymers Based on Functionalized Bis-terpyridines as Novel Electrochromic Materials” F. Han, M. Higuchi, D. G. Kurth, Adv. Mater., 2007, 19, 3928.

20、“Design and Synthesis of Thiazoline-Thiazole Hybrid Macrocycles Possessing Strong Affinity to Pb2+ and Cd2+” F. Han, H. Tokuyama, T. Fukuyama, Chem. Comm., 2007, 3444.

19、“Novel Bis-2,2’:6’,2”-terpyridines: Synthesis, Fabrication of Metallosupramolecular Polymers and Electrochemical Properties” F. Han, M. Higuchi, A. Yumeno, Y. Otsuka, D. Kurth, Thin Solid Films, 2008, 516, 2469.(special issue)

18、“Novel Structural Motifs Consisting of Chiral Thiazolines: Synthesis, Molecular Recognition, and Anticancer Activity” F. Han, H. Osajima, M. Cheung, H. Tokuyama, and T. Fukuyama, Chem. Eur. J. 2007, 13,3026. (Selected as inside cover page)

17、“Diverse Synthesis of Novel Bisterpyridines via Suzuki-Type Cross-Coupling” F. Han, M. Higuchi, D. Kurth, Org. Lett., 2007, 9, 559-562.

16、“Synthesis of Chiral Cyclic Oligothiazolines: A Novel Structural Motif for a Macrocyclic Molecule”, F. Han, H. Osajima, M. Cheung, H. Tokuyama, and T. Fukuyama, Chem. Comm. 2006, 1757-1759.

15、“Resolution of Synthetically Useful myo-Inositiol Derivatives Using the Chiral Auxiliary O-Acetylmandelic Acid” K. M. Sureshan, Y. Kiyosawa, F. Han, A. Hyodo, Y. Uno, Y. Watanabe Tetrahedron: Asymmetry, 2005, 16, 231.

14、“Chemo-resolution of 1,2-O-cyclohexylidene-3,4-O-(tetraisopropyl- disiloxane-1,3-diyl)-myo-inositol and Synthesis of Phosphatidyl- D-myo-inositol 3,5-bisphosphate from both L- and D- Enantiomers” F. Han, Minoru Hayashi, Yutaka Watanabe Eur. J. Org. Chem., 2004, 558.

13、 “Regioselective Phosphorylation of Vicinal 3,4-Hydroxyl myo-Inositol Derivative Promoted Practical Synthesis of D-PtdIns(4,5)P2 and Ins(1,4,5)P3” F. Han, M Hayashi and Y. Watanabe, Tetrahedron, 2003, 59, 7703.

12、“Enantiomerically Convergent Synthesis of Phosphatidyl-D-myo-inositol 3,5-bisphosphate from both L- and D-1,2-O-cyclohexylidene myo-inositol” F. Han, M Hayashi, Y Watanabe Chem. Lett., 2003, 32, 724.

11、“A Short Synthesis of Dipalmitoylphosphatidylinositol 4,5-Bisphosphate via 3-O-Selective Phosphorylation of a 3,4-Free Inositol Derivative”, F. Han, M Hayashi, Y Watanabe Chem. Lett., 2003, 32, 46.

10、“Diastereoselective Henry Reactions of N,N-Dibenzyl aldehyde with Nitromethane Catalyzed by Enantiopure Gudaidines”, DW Ma, QB Pan, F. Han, Tetrahedron Lett., 2002, 43, 9401.

9、Progress in the Chemistry of Spirodilatone and Its Derivatives², JQ Qu, DQ Wang, F. Han, MX Ding, LX Gao, Chem. J. Chin. Univ., 2001, 22, 851. (Chinese)

8、Resolution of 3,3¢-dioxo-[1,1]-spirodiphthalan-5,5¢,6,6¢-tetracarboxylic Acid and Optically Active Polyimides Thereof², F. Han, JQ Qu, X Zhang, MX Ding LX Gao, Chin. Chem. Lett., 2000, 11, 1077.

7、Synthesis of Aromatic DiaminoSpirodilatoones², JQ Qu, DQ Wang, F. Han, MX Ding, LX Gao, Chem. J. Chin. Univ.-Chin., 2000, 21, 1939.

6、Polyimides from 3,3¢-dioxo-[1,1]-spirodiphthalan-5,5¢,6,6¢-tetracarboxylic

dianhydride², F. Han, LX Gao, MX Ding, Polymer, 1999, 40, 3809.

5、Crosslinking Polyimides via Spirodilactone Unit in Polymer Backbone², F. Han, MX Ding, LX Gao, J. Poly. Sci., Part A: Polymer Chemistry, 1999, 37, 3680.

4、Syntheses of a New Kind of Polyamides and Polyesters Including Aromatic Spirodilactone², J Yang, F. Han, LX Gao, MX Ding, Acta Polymerica Sinica, 1999, 5, 520 (Chinese).

3、Thermoregulated Phase-transfer Ligands and CatalysisVII. Cloud Point of Nonionic Surface-active Phosphine Ligands and Their Thermoregulated Phase-transfer Property², JY Jang, YH Wang, C Liu, F. Han, ZL Jin, Journal of Molecular Catalysis A: Chemical, 1999,147, 131.

2、Synthesis of Aromatic Spirodilactones and Spirodilatams², F. Han, LX Gao, MX

Ding, Chin. J. Org. Chem., 1997, 5(suppl.), 700. (Chinese)

1、Study on the Property of Complex Alkali Earth Catalyst for Ethoxylation of Narrow Distribution ², F. Han, ZL Jin, Jing Xi Hua Gong, 1997, 14, 14.