课题组简介
最小化 最大化

杂环化学课题组依托于中国科学院合成橡胶重点实验室，主要致力于四元、五元、六元杂环以及稠杂环的高效选择性合成方法学研究，并探索功能杂环分子在可控聚合与生物医用领域方面的应用。主要研究兴趣涵盖杂环、芳环类化合物的合成方法；活性可控表面引发聚合方法；具有生物活性杂环分子与生物相容型高分子；有机硅中间体与有机氟硅高分子等领域。
招聘信息 招聘信息
最小化 最大化

课题组热忱欢迎有志青年的加入，欢迎报考本组的研究生，以博士后或职工的身份加入课题组，优秀博士毕业生或博士后可优先推荐出国深造或留所工作，本招聘公告长期有效。

董德文　研究员
   

博士生导师，杂环化学课题组组长

合成楼二期221室

电话：

传真：

Email：dwdong@ciac.ac.cn

 

 
教育和工作经历

  

            1985-1989                              东北师范大学化学系，学士学位

            1989-1992                              东北师范大学化学系有机化学专业，硕士学位

            1996-1999                              中国科学院长春应用化学研究所高分子化学与物理专业，博士学位

            1992-1996                              中国科学院长春应用化学研究所，助理研究员

            1999-2001                              日本静冈大学(Shizuoka University)，特别研究员、非常勤讲师

            2001-2003                              英国赫尔大学(The University of Hull), 博士后研究员

            2004-2006                              东北师范大学化学学院，教授，博士生导师

            2006-现在                               中国科学院长春应用化学研究所，研究员，博士生导师
 
主要荣誉

             2005年获吉林省优秀留学回国人员称号

         2013 年获吉林省自然科学奖二等奖，获奖名称："杂环化合物合成方法学研究"
 研究领域介绍：

鉴于杂环类化合物在有机合成化学以及生物活性物质中发挥的重要作用，我们从简单合成前体如1,3-二羰基化合物及其具有多活性官能化结构的衍生物出发，利用现代合成手段如：维尔斯迈尔反应、有机氧化反应、过渡金属催化的缩合反应、电环化与重排反应等，建立系列四元、五元、六元杂环化合物的合成策略。阐明新方法中杂环构建、高效催化、绿色合成所涉及的反应机理、选择性等基本科学问题，形成新理论，为具有生物活性的杂环母核构建提供新的合成技术与理论依据。

 高分子化学
最小化 最大化

智能高分子与表面

我们长期从事简单、高效聚合方法的开发与利用工作，并致力于功能型零维、一维、二维与三维聚合物刷的设计制备、结构研究与应用探索。

研究兴趣一：

从功能性单体与催化剂的设计合成入手，探寻功能性单体的可控高效聚合方法，制备具有不同拓扑结构的刺激响应型聚合物，为功能聚合物材料的制备提供简便高效的制备方法的同时，也为理解材料结构与性质之间的关系提供理论与实验参考。

                                                      

研究兴趣二：

在具有不同几何结构的有机、无机材料表面与界面，通过共价键接枝化学成分可调、结构可控的聚合物刷，建立简单高效的表面引发活性聚合方法，探索聚合物刷在功能防护、能源、催化、光电与生物医用等领域的应用。
有机氟硅高分子材料
最小化 最大化

研究领域介绍：

    含硅聚合物的分子结构设计、制备与应用研究。探索功能有机硅聚合物结构与性能的关系，通过与功能性有机高分子预聚物的接枝、共聚、共混等手段，制备新型有机硅材料。
    有机硅纳米结构材料的研究。通过分子结构单元尺寸和构型的控制，制备新型有机硅纳米结构材料，并开展其在催化、分子探针、多孔材料等领域的研究。

研究成果


2019 2019
最小化 最大化

    B. Deng, C. B. Rao, R. Zhang, J. Li, Y. Liang, Y. Zhao,* M. Gao, D. Dong,* A Formal [3+2] Annulation of β-Oxoamides and 3-Alkyl/Arylprop-2-ynyl Sulfonium Salts: Substrate-Controlled Chemoselective Synthesis of Substituted γ-Lactams and Furans, Advanced Synthesis & Catalysis 2019, 361, 4549-4557.
    J. Yuan, B. Deng, Y. Liang, C. B. Rao, R. Zhang,* Y. Zhao, D. Dong,* PIFA/TEMPO-Mediated Oxidative Cascade Cyclization of α-[(β-Amino)propenoyl]-Alkylamides: Access to Polysubstituted 3,7-Dihydrooxazolo[4,5-c]pyridine-2,4,6(5H)-triones, Advanced Synthesis & Catalysis 2019, 361, 4324-4333.
    J. Yuan, C. B. Rao, Y. Liang, R. Zhang,* Q. Zhang, L. Hou, D. Dong,* Copper-Catalyzed Regioselective Oxidative Cycloamidation of α-[(β-Dimethylamino)propenoyl]-Alkylamides: Synthetic Route to Substituted Pyrrolidine-2,4-diones, Advanced Synthesis & Catalysis 2019, 361, 160-169.
     Q. Wang, S. Chen, B. Deng, Y. Wang, D. Dong,* N. Zhang,* Rare Earth Metal-Mediated Ring-opening Polymerisation of Cyclic Phosphoesters, Polymer Chemistry 2019, 10, 2101-2105.
    B. Deng, C. Li, J. Yuan, C. B. Rao, Y. Zhao,* R. Zhang, D. Dong,* Synthesis of Substituted Dihydro-1H-pyrazoles and 1H-Pyrazoles via Formal [4+1] Annulation of α-Arylhydrazonoketones and Dimethylsulfonium Methylides,Tetrahedron 2019, 75, 2273-2279.

2018 2018
最小化 最大化

    L. Hou, Y. Liang, Q. Wang, Y. Zhang,* D. Dong, N. Zhang,* Lewis Pair-Mediated Surface-Initiated Polymerization, ACS Macro Letters 2018, 7, 65-69.

    C. B. Rao, J. Yuan, Q. Zhang, R. Zhang,* N. Zhang, J. Fang, Dewen Dong,* Iodosobenzene-Mediated α‑Acyloxylation of 1,3-Dicarbonyl Compounds with Carboxylic Acids and Insight into the Reaction Mechanism, Journal of Organic Chemistry 2018, 83, 2904-2911.

    C. Li, J. Yuan, Q. Zhang, C. B. Rao, R. Zhang,Y. Zhao, B. Deng, Dewen Dong, Oxidative Cyclization of β-Aminoacrylamides Mediated by PhIO: Chemoselective Synthesis of Isoxazoles and 2H-Azirines,  Journal of Organic Chemistry, 2018, 83, 14999-15008.

    S. Chen, L. Hou, Q. Wang, D. Dong, N. Zhang,* Facile Synthesis of Cylindrical Molecular Brushes via Lewis Pair-Mediated Polymerization, Polymer Chemistry 2018, 9, 5470-5475.

    C. Wang, Y. Li, Y. Ma, Y. Gao,* D. Dong, J. Fang, N. Zhang,* Thermoresponsive Polymeric Nanoparticles Based on Poly(2-Oxazoline)s and Tannic Acid, Journal of Polymer Science, Part A: Polymer Chemistry 2018, 56, 1520-1527.

    J. Yuan, C. B. Rao, Q. Zhang, R. Zhang,* Y. Liang, N. Zhang, Dewen Dong,* PIFA-Mediated Oxidative Cyclization Reactions of α-Acyl Acrylamides: A Synthetic Route to Substituted Isoxazol-3(2H)-ones, Synthesis 2018, 50, 1875-1882.

2017 2017
最小化 最大化

    Q. Wang, S. Chen, Y. Liang, D. Dong, N. Zhang,* Bottle-Brush Brushes: Surface-Initiated Rare Earth Metal Mediated Group Transfer Polymerization from a Poly(3-((2,6-dimethylpyridin-4-yl)oxy)propyl methacrylate) Backbone, Macromolecules 2017, 50, 8456−8463.
    L. Hou, M. Zhou, X. Dong, L. Wang, Z. Xie, D. Dong, N. Zhang,* Controlled Growth of Metal-Organic Frameworks on Polymer Brushes, Chemistry - A European Journal 2017, 23, 13337-13341.
    L. Hou, J. Fang, W. Wang, Z. Xie, D. Dong, N. Zhang,* Indocyanine green-functionalized bottle brushes of poly(2-oxazoline) on cellulose nanocrystals for photothermal cancer therapy, Journal of Materials Chemistry B 2017, 5, 3348-3354.
    Q. Zhang, J. Yuan, M. Yu, R. Zhang,* Y. Liang, P. Huang, D. Dong,* Triflic Anhydride Promoted Intramolecular Cyclization of N-Aryl Cinnamides: Access to Polysubstituted Quinolin-2(1H)-ones, Synthesis 2017, 49, 4996-5002.

2016 2016
最小化 最大化

    H. Bian, J. Yang, N. Zhang,* Q. Wang, Y. Liang, D. Dong,* Ultrathin free-standing polymer membranes with chemically responsive luminescence via consecutive photopolymerizations, Polymer Chemistry, 2016, 7, 1191-1196.
    L. Hou, L. Wang,  N. Zhang,* Z. Xie, D. Dong, Polymer brushes on metal-organic frameworks by UV-induced photopolymerization, Polymer Chemistry, 2016, 7, 5828-5834.
    M. Yu, Q. Zhang, G. Li, J. Yuan, N. Zhang,* R. Zhang, Y. Liang, D. Dong,* Copper-Nitrene Triggered Annulation of α-Acyl Cinnamides: Access to Isoxazol-3(2H)-ones, Advanced Synthesis & Catalysis, 2016, 358, 410-416.
    Q. Zhang, M. Yu, J. Yuan, R. Zhang,* Y. Liang, J. Tian, D. Dong,* Formal [4+1] Annulation of alpha-Arylhydrazonoketones and Dimethylsulfoxonium Methylide: One-pot Synthesis of Substituted Pyrazoles and Dihydropyrazoles, Journal of Organic Chemistry, 2016, 81, 6036-6041.
    L. Hou, H. Bian, Q. Wang, N. Zhang,* Y. Liang, D. Dong,* Direct Functionalization of Cellulose Nanocrystals with Polymer Brushes via UV-induced Polymerization: Access to Novel Heterogeneous Visible-light Photocatalysts, RSC Advances 2016, 6, 53062-53068.
    M. Yu, Q. Zhang, J. Wang, P. Huang, P. Yan,* R. Zhang, D. Dong* Triflic Anhydride-Mediated Beckmann Rearrangement Reaction of β-Oximyl Amides: One-pot Access to 5-Iminooxazolines, Journal of Chemical Sciences 2016, 128, 951-956.
    Y. Yang,* C. Gao, N. Zhang, D. Dong,* Tetraphenylethene functionalized rhodamine chemosensor for Fe3+ and Cu2+ ions in aqueous media, Sensors and Actuators B: Chemical 2016, 222, 741-746.
    M. Yu, Q. Zhang, J. Wang, P. Huang, P. Yan,* R. Zhang, D. Dong* Triflic Anhydride-Mediated Ring-opening/Recyclization Reaction of α-Carbamoyl-α-Oximyl Cyclopropanes with DMF: Synthetic Route to 5-Aminoisoxazoles, Synthesis 2016, 48, 1934-1938.
    Y. Yang,* C. Gao, J. Chen, N. Zhang, D. Dong,* A pyrene-based fluorescent and colorimetric chemodosimeter for the detection of ClO- ions, Analytical Methods 2016, 8, 805-809.
    Y. Yang,* C. Gao, J. Liu, D. Dong,* Recent developments in the rhodamine salicylidene hydrazine chemosensors, Analytical Methods 2016, 8, 2863-2871.

2015 2015
最小化 最大化

    J. Yang, D. Xiang, R. Zhang, N. Zhang,* Y. Liang, X. Xin, D. Dong,* POCl3-Mediated Reaction of 1-Acyl-1-Carbamoyl Oximes: A New Entry to Cyanoformamides, Organic Letters 2015, 17, 809-811.
    J. Yuan, Q. Zhang, M. Yu, P. Huang,* R. Zhang, D. Dong,* Phenyliodine(III) Diacetate Mediated Oxidative Cyclization of 1‑Alkenoyl-1-carbamoyl Cycloalkanes: Access to Spiro-Fused Dihydrofuran-3(2H)‑ones, Organic Letters 2015, 17, 5012-5015.
    L. Shi, Q. Zhang, F. Gan, R. Zhang,* Y. Ding, C. Liu, D. Dong,* PBr3-mediated [5 + 1] annulation of a-alkenoyl-a-carbamoyl ketene-S,S-acetals: access to substituted pyridine-2,6(1H,3H)-diones, RSC Advances, 2015, 5, 82743-82747.
    J. Yang, N. Zhang,* H. Li, B. Xu, W. Tian, D. Dong,* Polymer Grafts on Zirconia Particles and Its Application as Supports of Hybrid Catalyst, Polymer International 2015, 64, 804-810.

2014 2014
最小化 最大化

    Q. Zhang, X. Liu, X. Xin, R. Zhang,* Y. Liang, D. Dong,* Formal [4+2] Annulation of Enaminones and Cyanomethyl Sulfur Ylide: One-Pot Access to Pyridin-2(1H)-ones, Chemical Communications 2014, 50, 15378-15380.
    Z. Wang, X. Bi, Y. Liang,* P. Liao, D. Dong,* Copper-Catalyzed Formal O-H Insertion Reaction of α-Diazo-1,3-Dicarb-Onyl Compounds to Carboxylic Acids with The Assistance of Isocyanide, Chemical Communications 2014, 50, 3976-3978.
    C. Liu, Y. Li, J. Ding, D. Dong, F. Han,* The Development of Copper-Catalyzed Aerobic Oxidative Coupling of H-Tetrazoles with Boronic Acids and An Insight Into The Reaction Mechanism, Chemistry - A European Journal 2014, 20, 2373-2381.
    J. Yang, L. Hou, B. Xu, N. Zhang,* Y. Liang, W. Tian, D. Dong,* Polymer Brushes on Planar TiO2 Substrate, Macromolecular Rapid Communications  2014, 35,1224-1229.
    J. Yang, Y. Liang, S. Salzinger, N. Zhang,* D. Dong, B. Rieger,* Poly(vinylphosphonate)s Functionalized Polymer Microspheres via Rare Earth Metal-mediated Group Transfer Polymerization, Journal of Polymer Science Part A: Polymer Chemistry 2014, 52, 2919-2925.
    X. Xin,X. Liu,D. Zhang, R. Zhang,Y. Liang,* F. Han,D. Dong,* Divergent Synthesis of 2,3-Dihydro-1H-pyrroles, 3-Alkyl-1H-Pyrroles and 3-Alkenyl-1H-Pyrroles from 2,4-Pentadienenitriles and Isocyanide,Organic and Biomolecular Chemistry 2014, 12, 5477-5483.
    X. Xin, Q. Zhang, Y. Liang,* R. Zhang, D. Dong,* Tandem Halogenation/Michael-Initiated Ring-Closing Reaction of α,β-Unsaturated Nitriles and Activated Methylene Compounds: One-Pot Diastereoselective Synthesis of Functionalized Cyclopropanes, Organic and Biomolecular Chemistry 2014, 12, 2427-2435.
    F. Zhou, N. Zhang, Y. Liang,* X. Xin, X. Zhang, R. Zhang, D. Dong,* Synthesis of Multi-Substituted4-Aminopyridines via Ring-Opening and Recyclization Reactions of 2-Iminopyridines, RSC Advances 2014, 4, 18198-18204.
    X. Liu, Q. Zhang, X. Xin, R. Zhang, N. Zhang,* Y. Liang, D. Dong,* BF3·Et2O-Mediated Intramolecular Cyclization of Unsaturated Amides: Regioselective Synthesis of Dihydroquinolin-2-One-BF2 Complexes, RSC Advances 2014, 4, 36234-36240.
    B. S. Soller, N. Zhang,*  B. Rieger,* Catalytic Precision Polymerization: Rare Earth Metal-Mediated Synthesis of Homopolymers, Block Copolymers, and Polymer Brushes, Macromolecular Chemistry and Physics 2014, 215, 1946-1962. (Invited Review)
    N. Zhang, D. Dong, Formylation and the Vilsmeier Reagents,  in C-1 Building Blocks in Organic Synthesis, Volume 2, book chapter, 333-347, Georg Thieme Verlag KG, Stuttgart, 2014, Editor: P. W. N. M.van Leeuwen.
    梁永久, 黄鹏,* 张睿, 董德文,* β-氧代酰胺衍生物的Vilsmeier反应在杂环化合物合成中的应用, 有机化学, 2014, 6, 1037-1047. （邀请综述，封面）

2013 2013
最小化 最大化

    N. Zhang,* S. Salzinger, B. S. Soller, B. Rieger,* Rare Earth Metal-Mediated Group Transfer Polymerization: From Defined Polymer Microstructures to High Precision Nano-Scaled Objects, Journal of the American Chemical Society 2013,135, 8810-8813.
    D. Zhang, Q. Zhang, R. Zhang, Y. Liang, D. Dong,* Formal [4+1] Annulation of α,α-Dialkyl β-Oxo Amides and Dimethylsulfoxonium Methylide: a Synthetic Route to β-Hydroxy-γ-Lactams, Chemical Communications 2013, 49, 7358-7360.
    Z. Wang, X. Bi,* P. Liao, X. Liu, D. Dong,* Cu(II)-Catalyzed Cyclization of α-Diazo-β-Oxoamides with Amines Leading to Pyrrol-3(2H)-Ones, Chemical Communications 2013, 49,1309-1311.
    F. Zhou, X. Liu, Y. Liang, R. Zhang, N. Zhang,* X. Xin, D. Dong,* Copper-catalyzed Three-component Reaction: Solvent-controlled Regioselective Synthesis of 4-Amino-and 6-Amino-2-Iminopyridines, Organic Letters 2013, 15, 5786-5789.
    X. Liu, Q. Zhang, D. Zhang, X. Xin, J. Yang, R. Zhang, F. Zhou, D. Dong,* PPA-Mediated C-C Bond Formation: a Synthetic Route to Substituted Indeno[2,1-c]Quinolin-6(7H)-ones, Organic Letters 2013, 15, 776-779.
    X. Xin, D. Xiang, J. Yang, Q. Zhang, F. Zhou, D. Dong,* Homogeneous and Stereoselective Copper(II)-Catalyzed Monohydration of Methylene-malononitriles to 2-Cyanoacrylamides, Journal of Organic Chemistry 2013, 78, 11956-11961.
    X. Liu, N. Zhang, J. Yang, Y. Liang, R. Zhang, D. Dong,* Hydrogen Bond-Assisted 6π-Azaelectro Cyclization of Penta-2,4-Dienamides: Synthesis of Dihydropyridin-2(3H)-Ones, Journal of Organic Chemistry 2013, 78, 3323-3328.
    X. Xin, P. Huang, D. Xiang, R. Zhang, F. Zhao, N. Zhang, D. Dong,* [5C + 1N] Annulation of 2,4-Pentadienenitriles with Hydroxylamine: A Synthetic Route to Multi-Substituted 2-Aminopyridines, Organic and Biomolecular Chemistry 2013, 11, 1001-1006
    X. Liu, X. Xin, D. Xiang, Y. Liang,* X. Xin, W. Li, D, Dong,* One-pot Synthesis of Substituted 2,5-Dihydrofurans from β-Oxo Amides and Cinnamaldehydes, RSC Advances 2013, 3, 1346-1349.
    D. Xiang, X. Bi,* P. Liao, Z. Wang, X. Xin, D, Dong,* Solvent-Controlled, Regio-Switchable Formation of 3-Arylamino- or 5-Arylaminopyrazole Isomer in The Cyclocondensation of b-Aminoenones with Hydrazides: Intermolecular Hydrogen Bonding Plays The Role, RSC Advances 2013, 3, 386-389.
    J. Wang, H. Li,* D. Zhang, R. Zhang,* P. Huang, Y. Liang, D. Dong, Divergent Synthesis of α,α-Dihaloamides via α,α-Dihalogenation of β-Oxo Amides using N-Halosuccinimides, European Journal of Organic Chemistry 2013, 69, 5376-5380.

2012 2012
最小化 最大化

    N. Zhang, S. Salzinger, F. Deubel, R. Jordan, B. Rieger,* Surface-Initiated Group Transfer Polymerization Mediated by Rare Earth Metal Catalysts, Journal of the American Chemical Society 2012, 134, 7333-7336.
    N. Zhang,* S. Salzinger, B. Rieger,* Poly(vinylphosphonate)s with Widely Tuneable LCST: A Promising Alternative to Conventional Thermoresponsive Polymers, Macromolecules 2012, 45, 9751-9758. (Most read article in 2013.01)
    Y. Hu, X. Fu, B. Barry, X. Bi,* D. Dong,* One-Pot Synthesis of N-Aryl-3-Spirocyclic-β-Lactams and Further Regiospecific β-Lactam Ring-Opening/Recyclization Reactions Catalyzed by Lewis-Brønsted Acids Combined Superacid Catalyst System: A New Entry to 3-Spirocyclicquinolin-4(1H)-Ones, Chemical Communications 2012, 48, 690-692.
    Z. Wang, X. Bi,* P. Liao, R. Zhang, Y. Liang, D. Dong,* The Catalytic Wolff 1,2,3-Triazole Synthesis: Intramolecular Hydrogen Bonding-Assisted Cyclocondensation of α-Diazo-β-Oxoamides with Various Amines, Chemical Communications 2012, 48, 7076-7078.
    P. Huang, R. Zhang, Y. Liang, D. Dong,* [5C + 1N] Annulations: Two Novel Routes to Substituted Dihydrofuro[3,2-c]Pyridines, Organic Letters 2012, 14, 5196-5199.
    P. Huang, N. Zhang,* R. Zhang, D. Dong,* Vilsmeier-type Reaction of Dimethylaminoalkenoyl Cyclopropanes: One-Pot Access to 2,3-Dihydrofuro [3,2-c]Pyridine-4(5H)-Ones, Organic Letters 2012, 14, 370-373.
    D. Xiang, X. Xin, X. Liu, R. Zhang,* J. Yang, D. Dong,* Regioselective Synthesis of 3-Arylamino- and 5-Arylamino-isoxazoles from Enaminones, Organic Letters 2012, 14, 644-647.
    N. Zhang, T. Pompe,* I. Amin, R. Luxenhofer, C. Werner, R. Jordan,* Tailored Polymer Brushes of Poly(2-oxazoline)s to Control the Protein Adsorption and Cell Adhesion’ Macromolecular Bioscience 2012, 12, 926-936. (Most accessed in 2012.7, cover article)
    N. Zhang, R. Luxenhofer, R. Jordan,* Thermo-responsive Poly(2-oxazoline) Molecular Brushes by Living Ionic Polymerization: Modulation of the Cloud Point by Random and Block Copolymer Pendant Chains, Macromolecular Chemistry and Physics 2012, 213, 1963-1969.
    N. Zhang, R. Luxenhofer, R. Jordan, Thermo-responsive Poly(2-oxazoline) Molecular Brushes by Living Ionic Polymerization: Kinetic Investigations of Pendant Chain Grafting and Cloud Point Modulation by Backbone and Side Chain Length Variation, Macromolecular Chemistry and Physics 2012, 213, 973-981. (Most accessed in 2012.6)
    C. Wu, J. Wang, P. Chang, H. Cheng, Y. Yu, Z. Wu, D. Dong, F. Zhao,* Polyureas from Diamines and Carbon Dioxide: Synthesis, Structures and Properties, Physical Chemistry Chemical physics 2012, 14, 464-468.
    P. Huang, R. Zhang, Y. Liang, D. Dong,* Lawesson's Reagent-Initiated Domino Reaction of Aminopropenoyl Cyclopropanes: Synthesis of Thieno[3,2-c]Pyridinones, Organic and Biomolecular Chemistry 2012, 10, 1639-1644.
    X. Liu, X. Xin, D. Xiang, R. Zhang, S. Kumar and D. Dong,* H2SO4-Mediated Cyclization of Penta-2,4-Dienamides: Facile and Efficient Synthesis of Quinolin-2(1H)-Ones, Organic and Biomolecular Chemistry 2012, 10, 5043-5646.
    D. Zhang, R. Zhang, D. Xiang, Y. Liang, D. Dong,* Formal [4+1]Annulation of Cyclopropyl Amides and Water Mediated by Lewis Acid: A Novel Entry to γ-Butyrolactones, Synthesis 2012, 1679-1685.
    D. Zhang, R. Zhang, D. Xiang, N. Zhang,* Y. Liang, D. Dong,* Efficient and Divergent Synthesis of Functionalized Cyclopropanes via Iodoform Reaction, Synthesis 2012, 705-710.
    B. Gao, D. Dong, J. Zhang, C. Ding,* Y. Liang, R. Zhang,* A Facile One-Pot Synthesis of Substituted Thieno-[2,3-b]-Pyridines from Enaminones, Synthesis 2012, 201-206.
    P. Huang, X. Fu, Y. Liang, R. Zhang, D. Dong,* Divergent Synthesis of Benzo [d]-Thiazoles via PIFA-Mediated Cyclization of -Oxo Thioamides, Australian Journal of Chemistry 2012, 65, 121-128.
    N. Zhang, T. Pompe, R. Luxenhofer, C. Werner, R. Jordan,* Poly(2-oxazoline) Bottle-brush Brushes for the Control of Protein Adsorption and Cell Adhesion, Polymer Preprints 2012, 53, 301-302.
    [13]  欧阳艳, 张睿, 何晓燕, 黄杰, 张月梅, 董德文, [5C+1N]成环反应:吡啶4(1H)酮类化合物的一种简便合成方法([5+1]Annulations: A Facile Synthetic Strategy towards Substituted Pyridine-4(1H)-Ones, 应用化学, 2012, 29, 1011-1016.

2011 2011
最小化 最大化

    M. Steenackers, A. M. Gigler, N. Zhang, F. Deubel, M. Seifert, L. H. Hess, C. H. Y. X. Lim, K. P. Loh, J. A. Garrido, R. Jordan, M. Stutzmann, I. D. Sharp,* Polymer Brushes on Graphene, Journal of the American Chemical Society 2011, 133, 10490-10498.
    I. Amin, M. Steenackers, N. Zhang, R. Schubel, A. Beyer, A. Gölzhäuser,* R. Jordan,* Polymer Carpets, Small 2011, 7, 683-687. (cover article)
    R. Zhang, D. Zhang, D. Dong,* Vilsmeier Reaction of 3-Aminopropenamides: One-Pot Synthesis of Pyrimidin-4(3H)-Ones, Journal of Organic Chemistry 2011, 76, 2880-2883.
    X. Fu, P. Huang, G. Zhou, Y. Hu, D. Dong,* Divergent Synthesis of Fully Substituted Isoxazoles and Spiro-Fused Pyrazolin-5-Ones from Cyclopropyl Oximes, Tetrahedron 2011, 67, 6347-6351.
    X. Yang,* Y. Cheng, F. Zhao, Y. Li, Y. Ding, Y. Liang, F. Gan, D. Dong,* A Facile and Efficient Synthesis of Fully Substituted Pyridin-2(1H)-Ones from a-Oxoketene-S,S-Acetals, Tetrahedron 2011, 67, 8343-8347.
    D. Xiang, X. Xin, X. Liu, S. Kumar and D. Dong,* One-Pot Synthesis of Pyrano[2,3-b]Quinolines from Enaminones under Solvent-Free Conditions, Synlett 2011, 2187.
    D. Xiang, Copper(I) Bromide, Synlett 2011, 2187.

2010 2010
最小化 最大化

    I. Amin, M. Steenackers, N. Zhang, A. Beyer, X. Zhang, T. Pirzer, T. Hugel, R. Jordan,* A. Gölzhäuser,* Patterned Polymer Carpets, Small 2010, 6, 1623-1630. (cover article)
    X. Xin,Y. Wang, W. Xu,Y. Lin,H. Duan, D. Dong,* A Facile and Efficient One-Pot Synthesis of Polysubstituted Benzenes in Guanidinium Ionic Liquids, Green Chemistry 2010, 12, 893-898.
    X. Xin, Y. Wang,S. Kumar,X. Liu,Y. Lin, D. Dong,* Efficient One-Pot Synthesis of Substituted Pyridines through Multicomponent Reaction, Organic and Biomolecular Chemistry 2010, 8, 3078-3082.
    N. A. Hutter, A. Reitinger,N. Zhang, M. Steenackers, O. Williams, J. A. Garrido,R. Jordan,* Microstructured Poly(2-oxazoline) Bottle-brush Brushes on Nanocrystalline Diamond, Physical Chemistry Chemical Physics 2010, 12, 4360-4366.
    W. Bao, M. Billa, K. Kassireddy, M. Haro, M. Kelly, S. Kitney, M. Kalifah, P. Wei, D. Dong, M. O'Neill, S. Kelly,* Carbazole Nematic Liquid Crystals, Liquid Crystals 2010, 37, 1289-1303.
    J. Liu, X. Fu, Y. Zhou, G. Zhou, Y. Liang, D. Dong,* A Facile and Divergent Synthesis of Substituted Pyridine-2,4(1H,3H)-Diones and 4H-Thiopyran-4-Ones from α-Alkenoyl-α-Carbamoyl Ketene-S,S-Acetals, Australian Journal of Chemistry 2010, 63, 1267-1271.

2009 2009
最小化 最大化

    N. Zhang, M. Steenackers, R. Luxenhofer, R. Jordan,* Bottle-brush Brushes: Cylindrical Molecular Brushes of Poly(2-oxazoline) on Glassy Carbon, Macromolecules 2009, 42, 5345-5351.
    N. Zhang, S. Huber, A. Schulz, R. Luxenhofer, R. Jordan,* Cylindrical Molecular Brushes of Poly(2-oxazoline)s from 2-Isopropenyl-2-oxazoline, Macromolecules 2009, 42, 2215-2221.
    Y. Wang, X. Xin, Y. Liang, Y. Lin,* H. Duan, D. Dong,* N,N,N',N'-Tetramethylchloroformamidinium Chloride-Mediated Cyclizations of b-Oxo Amides: Facile and Divergent One-pot Synthesis of Substituted 2H-Pyrans, 4H-Pyrans and Pyridin-2(1H)-ones, Advanced Synthesis & Catalysis 2009, 351,  2217-2223.
    K. Wang,X. Fu, J. Liu, Y. Liang,D. Dong,* PIFA-Mediated Oxidative Cyclization of 1-Carbamoyl-1-Oximylcycloalkanes: Synthesis of Spiro-Fused Pyrazolin-5-One N-Oxides, Organic Letters 2009, 11, 1015-1018.
    S. Dröge, M. O'Neill1,* A. Löbbert, S. P. Kitney, S. M. Kelly,* W. Pan, D. Dong, Photoalignment Using Photo-Addition to a Monolayer-Coated Surface, Nematic tolanes and acetylenes, Journal of Material Chemistry 2009,11, 274-279.
    Y. Wang, X. Xin, Y. Liang, Y. Lin, R. Zhang, D. Dong,* A Facile and Efficient One-Pot Synthesis of Substituted Quinolines from α-Arylamino Ketones Under Vilsmeier Conditions, European Journal of Organic Chemistry 2009, 4165-4169.
    Y. Ouyang, J. Huang,W. Pan, Y. Liang, Y. Yang,D. Dong,* [4+2] Annulation: Convenient Synthesis of Substituted Dihydropyranones in Aqueous Media, European Journal of Organic Chemistry 2009, 2003-2009.
    P. Huang, D. Xiang, Y. Zhou, Y. Liang,* T. Na,D. Dong,* A Facile and Practical One-pot Synthesis of β-Oxo Thioamides from β-Oxo Amides and Isothiocyanates, Synthesis 2009, 1797-1780.
    R. Zhang, Y. Zhou, Y. Liang, Z. Jiang, D. Dong,* Ring-Opening/Recyclization Reactions of Dimethyl Aminopropenoyl Cyclopropanes: Facile Synthesis of Halogenated Pyridin-2(1H)-Ones, Synthesis 2009, 15, 2497-2500.
    C. Ding, Y. Wang, W. Zhang, L. Lui, Y. Liang,D. Dong,* Convenient Synthesis of Substituted Quinoxalines and 2H-Benzo[b] [1,4] Oxazines in Water,  Chemical Research in Chinese Universities 2009, 25, 174-177.
    C. Liu, W. PAN, Y. YANG, K. Wang, D. Dong,* A Facile and Convenient One-Pot Synthesis of 1,1-Disubstituted Cyclo-Propanes in Water, Chemical Research in Chinese Universities 2009, 25, 37-39.

2008 2008
最小化 最大化

    D. Xiang, P. Huang, K. Wang, G. Zhou, Y. Liang, D. Dong,* Efficient and Divergent Synthesis of Cyclo- Phosphamide Analogues from 2-Arylamino-3-Acetyl-5,6-Dihydro-4H-Pyrans, Chemical Communications 2008, 6236-6238.
    K. Wang, D. Xiang, J. Liu, W. Pan, D. Dong,* Efficient and Divergent Synthesis of Fully Substituted 1H-Pyrazoles and Isoxazoles from Cyclopropyl Oximes, Organic Letters 2008, 10, 1691-1694.
    D. Xiang, K. Wang, Y. Liang, G. Zhou, D. Dong,* A Facile and Efficient Synthesis of Polyfunctionalized Pyridin-2(1H)-Ones from -Oxo Amides under Vilsmeier Conditions, Organic Letters 2008, 10, 345-348.
    R. Zhang, D. Zhang, Y. Guo, G. Zhou, Z. Jiang, D. Dong,* Vilsmeier Reaction of Enaminones: Efficient Synthesis of Halogenated Pyridin- 2(1H)-Ones, Journal of Organic Chemistry 2008, 73, 9504-9507.
    R. Zhang, Y. Liang, G. Zhou, K. Wang, D. Dong,* Ring Enlargement of Dimethylaminopropenoyl Cyclo-Propanes: An Efficient Route to Substituted 2,3-Dihydrofurans, Journal of Organic Chemistry 2008, 73, 8089- 8092.
    Y. Wang, J. Huang, Y. Chai, Q. Liu, Y. Liang, D. Dong,* Efficient One-Pot Synthesis of Highly Substituted Thiophene Library from 1,3-Dicarbonyl Compounds, Journal of Combinatorial Chemistry 2008, 10, 511-516.
    Y. Yang, D. Xiang, X. Zhao, Y. Liang, J. Huang, D. Dong,* Efficient Synthesis of -Alkylidene-Lactams via NaOH-Promoted Intramolecular Aza-Michael Addition of -Carbamoyl Ketene-S,S-acetals in Aqueous Media, Tetrahedron 2008, 64, 4959-4966.
    Y. Li, W. Li, R. Zhang, Y. Zhou, D. Dong,* A Facile One-Pot Synthesis of Substituted Pyridine-2,4(1H,3H)-Diones from α-Acyl-α-Carbamoyl Ketene-S,S-Acetals, Synthesis 2008, 3411-3414.
    C. Lin, X. Zhao, Y. Ouyang, H. Yu, D. Dong,* Solvent-Free Thia-Michael Addition Reactions Using 3-[Bis (alkylthio)Methylene]pentane-2,4- Diones as Efficient and Odorless Thiol Equivalents, Chinese Journal of Chemistry 2008, 26, 1431-1434.

2007 2007
最小化 最大化

    J. Huang, Y. Liang, W. Pan, Y. Yang, D. Dong,* Efficient Synthesis of Highly Substituted Pyrrolin-4-ones via PIFA-Mediated Cyclization Reactions of Enaminones, Organic Letters 2007, 9, 5345- 5348.
    W. Pan, D. Dong,* K. Wang, J. Zhang, R. Wu, D. Xiang, Q. Liu, Efficient One-Pot Synthesis of Highly Substituted Pyridin-2(1H)-Ones via The Vilsmeier-Haack Reaction of 1-Acetyl,1-Carbamoyl Cyclopropanes, Organic Letters 2007, 9, 2421-2423.
    M. A. Carrasco-Orozco, T. Stirner, M. O'Neill, C. Ellis, D. Dong, R. Kelly, M. Piepenbrock and S. M. Kelly, Superlattices of Organic/Inorganic Semiconductor Nanostructures from Liquid-Crystal Templates, Physical Review B 2007, 75, 035207.
    D. Xiang, Y. Yang, R. Zhang, Y. Liang, W. Pan, J. Huang, D. Dong,* Vilsmeier-Haack Reactions of 2- Arylamino-3-Acetyl-5, 6-Dihydro-4H-Pyrans towards the Synthesis of Highly Substituted Pyridin-2(1H)-Ones, Journal of Organic Chemistry 2007, 72, 8593-8596.
    Y. Wang, D. Dong,* Y. Yang, J. Huang, Y. Ouyang, Q. Liu, A Facile and Convenient One-Pot Synthesis of Polysubstituted Thiophenes from 1,3-Dicarbonyl Compounds in Water, Tetrahedron 2007, 63, 2724-2728.
    Y. Chai, D. Dong,* Y. Ouyang, Y. Liang, Y. Wang, M. Li, Q. Liu,  Thia-Michael Addition Reactions in Water Using 3-[Bis(alkylthio)methylene] Pentane-2,4-Diones as Odorless and Efficient Thiol Equivalents, Letters In Organic Chemistry 2007, 4, 281-284.
    W. Pan, D. Dong,* Y. Ouyang, R. Wu, Y. Yang, Q. Liu, Efficient Synthesis of Substituted Tetrahydro-Thiopyrano[2,3-b]Thiopyran-4,5-Diones by a Double Annulation Strategy from, -Dialkenoyl ketene-(S,S)-acetals, Synthesis 2007, 2115-2120.
    J. Huang, Y. Lu, B. Qiu, Y. Liang, N. Li, D. Dong,* One-Pot Synthesis of Substituted Isothiazol-3(2H)-Ones: Intramolecular Annulation of -Carbamoyl Ketene-(S,S)-Acetals via PIFA-Mediated N-S Bond Formation, Synthesis 2007, 2791-2796.
    H. Yu, D. Dong,* Y. Ouyang, Y. Wang, Q. Liu, NaOH-Promoted Thiolysis of Oxiranes Using 2-[Bis(alkylthio)menthylene]-3-Oxo-N-o- Tolylbutanamides as Odorless Thiol Equivalents, Synlett 2007, 151-155.
    Y. Ouyang, D. Dong,* Y. Liang, Y. Chai, Q. Liu, Acid-promoted Thioacetalization in Water Using 2-(1,3-Dithian-2-ylidene)Malonic Acid as An Odorless and Efficient Thioacetalization Reagent, Synthetic Communications 2007, 37, 993-1000.
    D. Zhu, W. Kang, D. Dong,  L. Xu, Q. Liu, A Novel Macrocyclic Dimeric Dicarboxylato Distannoxane Assembled from A Flexible Dicarboxylic Acid, Journal of Chemical Research 2007, 10, 577-579.
    刘丽, 李政, 李洪斌, 陆航, 丁长江, 董德文, 一步法合成多取代2-氨基噻酚衍生物，吉林大学学报（理学版）2007, 45, 853-856.

2006 2006
最小化 最大化

    Y. Ouyang, D. Dong,* H. Yu, Y. Liang, Q. Liu, A Clean, Facile and Practical Synthesis of -Oxo Ketene-(S,S)-Acetals in Water, Advanced Synthesis & Catalysis 2006, 348, 206-210.
    Y. Ouyang, D. Dong,* W. Pan, J. Zhang, Q. Liua, Facile and Clean Synthesis of -Alkenoyl Ketene-(S,S)-acetals via the Aldol Condensation Reactions in Water, Tetrahedron, 2006, 62, 10111-10116.
    M. P. Aldred, M. Carrasco-Orozco, A. E. A. Contoret, D. Dong, S. R. Farrar, S. M. Kelly, S. P. Kitney, D. Mathieson, M. O'Neill, W. C. Tsoi, P. Vlachos, Organic Electroluminescence using Polymer Networks from Smectic Liquid Crystals, Liquid Crystals 2006, 33, 459-467.
    Y. Ouyang, D. Dong,* C. Zheng, H. Yu, Q. Liu,* Z. Fu, Chemoselective Thioacetalization Using 3-(1,3-Dithian-2-Ylidene) Pentane-2,4-Dione as An Odorless and Efficient 1,3-Propanedithiol Equivalent under Solvent- Free Conditions, Synthesis 2006, 3801-3804.
    Y. Liang, D. Dong,* Y. Lu, Y. Wang, W. Pan, Y. Chai, Q. Liu, One-Pot Synthesis of Substituted 1-Pyrrolines through The Michael Addition of Nitroalkanes to Chalcones and Subsequent Reductive Cyclization in Aqueous Media, Synthesis 2006, 3301-3304.
    W. Pan, D. Dong,* S. Sun, Qun Liu, One-Pot Synthesis of Substituted Indole N-Oxides: TiCl4-mediated Baylis-Hillman Reaction of -Oxo Cyclic Ketene-S,S-Acetal with O-Nitrobenzaldehydes and Subsequent Intra-molecular Cyclization, Synlett 2006, 1090-1094.
    D. Dong,* H. Yu, Y. Ouyang, Q. Liu, X. Bi, Y. Lu, Thia-Michael Addition Reaction Using 2-[Bis(alkylthio)Methylene]-3-Oxo-N-O- Tolylbutanamides as Odorless and Efficient Thiol Equivalents, Synlett 2006, 283-287.
    D. Dong,* Y. Yang, B. Jiang, Sol-gel Approach to the Novel Organic-Inorganic Hybrid Composite Films with Ternary Europium Complex Covalently Bonded with Silica Matrix, Materials Chemistry and Physics 2006, 95: 89-93.
    张杰, 谭克, 毕锡和, 董德文, 刘群, 多取代5, 6二氢-4-噻喃并咪唑酮类化合物的合成，东北师大学报(自然科学版) 2006, 38, 87-89.
    欧阳艳, 于海丰, 董德文, 刘群, 无溶剂条件下代硫醇试剂与α, β-不饱和酮的迈克尔加成反应，东北师大学报(自然科学版) 2006, 38, 68-71.

2005 2005
最小化 最大化

    X. Bi, D. Dong,* Q. Liu*, W. Pan, L. Zhao, B. Li, [5+1] Annulation: A New Synthetic Strategy for Highly Substituted Phenols and Cyclohexenones, Journal of The Americal Chemical Society 2005, 127, 4578-4579.
    D. Dong,* X. Bi, Q. Liu, F. Cong, [5C+1N] Annulation: A Novel Synthetic Strategy for Functionalized 2,3-Dihydro-4-pyridones, Chemical Communications 2005, 28, 3580-3582.
    X. Bi, D. Dong,* Y. Li, Qun Liu, Q. Zhang, [5C+1S] Annulation: A Facile and Efficient Synthetic Route toward Functionalized 2,3-Dihydrothiopyran-4-Ones, Journal of Organic Chemistry 2005, 70, 10886-10889.
    D. Dong,* Y. Ouyang, H. Yu, Q. Liu, J. Liu, M.Wang, J. Zhu, Chemoselective Thioacetalization in Water: 3-(1,3-Dithian-2-Ylidene) Pentane-2,4-Dione as An Odorless, Efficient and Practical Thioacetalization Reagent, Journal of Organic Chemistry 2005, 70, 4535-4537.
    D. Dong,* R. Sun, H. Yu, Y. Ouyang, Q. Zhang, Q. Liu,* Facile Synthesis of Substituted Dihydro-1,4-Dithiins and-1,4-Dithiepins from -Oxo Ketene Cyclic Dithioacetals, Tetrahedron Letters 2005, 46, 7331-7335.
    S. Sun, Q. Zhang, Q. Liu, J. Kang, Y. Yin, D. Li and D. Dong, One-Pot Synthesis of Aza-Morita-Baylis-Hillman Adducts from -Oxo Ketene-S,S-Acetals, Arylaldehydes and Nitriles, Tetrahedron Letters 2005, 46, 6271-6274.
    H. Yu, D. Dong,* Y. Ouyang, Q. Liu, Chemoselective thioacetalization with odorless 2-(1,3-dithian-2-ylidene)-3-oxobutanoic acid as a 1,3-propanedithiol equivalent, Canadian Journal of Chemistry 2005, 83, 1741-1745.
    H. Yu, D. Dong,* Y. Ouyang, Q. Liu, Y. Wang, Acid-Promoted Cleavage of 4,4-Bis(alkylthio) But-3-En-2-One and Subsequent Michael Type Addition to, β-Unsaturated Ketones, Letters In Organic Chemistry 2005, 2, 755-759.
    M. P. Aldred, P. Vlachos, D. Dong, S. P. Kitney, W. C. Tsoi, M. O'Neill and S. M. Kelly, Heterocyclic Reactive Mesogens: Synthesis, Characterisation and Mesomorphic Behaviour, Liquid Crystals 2005, 32, 951-965.
    R. Sun, Q. Liu, H. Yu, Y. Zhao, J. Liu, Y. Ouyang, D. Dong,* Odorless and Practical Thioacetalization Reagent: Methyl 2-(1,3-Dithian-2-Ylidene)-3-Oxobutanoate, Chinese Journal Of Chemistry 2005, 23, 1060-1064.
    X. Bi, Q. Liu, S. Sun, J. Liu, W. Pan, L. Zhao and D. Dong,* A Facile and Efficient Synthesis of 3,5-Disubstituted Tetronic Acids in Aquous Media Involving Acid-Catalyzed Intramolecular Oxa-Pyridylethylation, Synlett 2005, 1, 49-54.
    D. Dong,* Y. Liu, Y. Zhao, Y. Qi, Z. Wang, Q. Liu,* Vilsmeier-Haack Reaction of β-Oxo Ketene Dithioacetals to α-Chlorovinyl/ Ethynyl Ketene Dithioacetals, Synthesis, 2005, 1, 85-91.
    欧阳艳, 于海丰, 董德文, 刘军, 王芒, 刘群, 2-（1, 3-亚丙二硫）亚甲基-3-羰基丁酸作为硫醇替代试剂在缩硫醛/酮化反应中的应用, 高等学校化学学报 2005, 26, 2237-2240.

合作单位
最小化 最大化

    The University of Hull, 英国
    Shizuoka University, 日本
    Technische Universität München, 德国
    Technische Universität Dresden, 德国
    Universität Würzburg, 德国
    Federal State Unitary Enterprise S.V. Lebedev Institute of Synthetic Rubber, 俄罗斯
    吉林大学
    东北师范大学

承担项目
最小化 最大化

1．多官能化酰胺化合物的高碘氧化反应导向的五元含氧杂环构建方法研究，国家自然科学基金, 2016.1-2016.12

2．基于α-羰基共轭烯酰胺类化合物的含氮杂环构建方法研究，国家自然科学基金青年基金, 2016.01-2018.12

3．高性能陶瓷化硅橡胶制备关键技术研发，江苏省科技厅重点研发计划项目，2015.6-2018.6

4．特种抗污节能氟碳涂料的研制与应用，长春市重大科技攻关项目，2014.12-2016.12

5. 刺激响应型自支持聚合物薄膜的设计制备与性质研究， 国家自然科学基金项目，2014.1-2016.12

6.  2-噁唑啉聚合物刷表面拓扑结构的设计制备与生物响应行为的研究，国家然科学基金项目，2014.1-2017.12

7.  酚醛基玻璃纤维发泡复合材料的研制，吉林省发改委吉林省产业技术研究与开发专项项目，2014.7-2016.6

8.  高阻燃聚氨酯保温板材关键技术研发及产业化，江苏省科技厅重大科技成果转化专项引导项目，2012.9-2014.8

9.  基于戊二烯腈的[5+1]成环反应研究，国家自然科学基金项目, 2012.1-2015.12

10.  军民两用防火有机硅密封/橡胶材料研制，科技部国际合作项目，2012.4-2015. 4

11.  氟硅化合物的防污节能涂料研制，长春市科技局国际合作项目，2011.8-2013.9

12.  基于氟硅化合物的防污节能涂料研制，吉林省科技厅吉林省科技发展重点项目，2011.8-2013.9

13. 基于手性膦配体的固载金属催化剂材料的设计、制备及其性能研究，国家自然科学基金项目，2011.1-2013.12

14. 吉林省绿色化学与过程研究创新团队，吉林省科技厅吉林省科技发展计划项目，2011.9-2013.9

15. 高阻燃聚氨酯泡沫材料的开发研究，中国科学院院地合作项目，2010.7-2013.6

16. 基于烯胺酮化学的杂环化合物合成方法学研究，国家自然科学基金项目，2009.1-2011.12

17. 可再生能源：液晶太阳能电池，国家自然科学基金委员会英国皇家学会中英合作项目，2007.4-2009.3

18. [5+1]成环反应构建六元碳环、杂环、芳环的合成新策略研究，国家自然科学基金项目，2006.1-2008.12

19. 哒螨酮合成新工艺的研究，吉林省科技厅吉林省科技发展重点项目，2005.1-2007.12

20. 环保型代硫醇试剂的研究与应用，教育部科学技术研究重点项目，2005.1-2007.12

21. 产生手性原因的基本问题，教育部科学技术研究重大项目，2004.1-2006.12