姓名：郝先
职务\职称：教研室主任、教授
系别：公共卫生与预防医学 卫生检验与检疫
研究方向：重大感染性疾病检测、生物传感器研发
工作邮箱：xian.hao@ncu.edu.cn
简介：2001年毕业于中国地质大学（北京）材料科学与工程学院，2011年1月在中国科学院长春应用化学研究所获得理学博士学位 。郝先博士先后在丹麦技术大学（Technical University of Denmark）、休斯顿大学（University of Houston）和加州大学（University of California, Merced）、法国巴斯德研究所（Institut Pasteur）进行博士后研究。先后获得丹麦大学联盟博士后奖学金和法国巴斯德研究所Roux-Cantarin****。现任南昌大学公共卫生学院卫生检验学教研室主任。江西省第二批“双千计划”入选者，南昌市预防医学会理事。主要从事重大感染性疾病检测、生物传感器和单分子分析仪器的研发。发表SCI论文24篇， 包括Nature Communications，Nano Letters，Small，Nanoscale等期刊。获权中国专利6项，省级科技进步奖1项。
论文、专著与专利：
1.Xian Hao, Eric A Josephs, Qufei Gu and Tao Ye, Molecular Conformations of DNA Targets Captured by Model Nanoarrays. Nanoscale, 2017, 9, 13419-13424.
2.Heng Liu*, Xian Hao*, Chunhui Duan*, Hui Yang*, Yi Lv, Haijiao Xu, Hongda Wang, F. Huang, Debao Xiao and Zhiyuan Tian. Al3+-Induced Far-red Fluorescence Enhancement of Conjugated Polymer Nanoparticles and Its Application in Live Cell Imaging, Nanoscale, 5 (2013), 9340-9347. (*共同一作).
3.Xian Hao, Nan Zhu, Tina Gschneidtner, Elvar ?. Jonsson, Jingdong Zhang, Kasper Moth-Poulsen, Hongda Wang, Kristian S. Thygesen, Karsten W. Jacobsen, Jens Ulstrup, Qijin Chi, Direct Measurement and Modulation of Single-molecule Coordinative Bonding Forces in a Transition Metal Complex, Nature Communications, 4 (2013), 2121.
4.Heng Liu*, Hui Yang*, Xian Hao*, Haijiao Xu, Yi Lv, Debao Xiao, Hongda Wang, and Zhiyuan Tian, Development of Polymeric Nanoprobes with Improved Lifetime Dynamic Range and Stability for Intracellular Oxygen Sensing, Small, 9 (2013), 2639-2648. (*共同一作).
5.Xian Hao, Jingdong Zhang, Hongda Wang, Hans E.M. Christensen and Jens. Ulstrup, Electrochemical Single-molecule AFM of the Redox Metalloenzyme Copper Nitrate Reductase in Action, ChemPhysChem, 13 (2012), 2919-2924.
6.Xian Hao*, Jiazhen Wu, Yuping Shan, Mingjun Cai, Xin Shang, Junguang Jiang, Hongda Wang, Caveolae-mediated Endocytosis of Biocompatible Gold Nanoparticles in Living Cells, Journal of Physics: Condensed Matter, 24 (2012), 164207.
7.Xian Hao, Xin Shang, Jiazhen Wu, Yuping Shan, Mingjun Cai, Junguang Jiang, Zhong Huang, Zhiyong Tang and Hongda Wang. Single-Particle Tracking of Hepatitis B Virus-like Vesicle Entry into Cells, Small, 7 (2011), 1212-1218. (封面文章)
8.Junguang Jiang*, Xian Hao*, Mingjun Cai, Yuping Shan, Xin Shang, Zhiyong Tang, and Hongda Wang. Localization of Na+-K+ATPases in Quasi-Native Cell Membranes, Nano Letters, 9 (2009): 4489-4493. (共同一作)
主持的科研项目：
1.2019.04-2024.04，南昌大学学科带头人启动经费，300万；
2.2013.01-2015.12，国家自然科学基金青年项目（**），单粒子示踪方法研究狂犬病毒与宿主细胞相互作用 ，27万