柴纬明 博士

副教授，硕士生导师（生物学）
● 学习、工作经历：
2014.06至今 江西师范大学生命科学学院讲师、副教授
2009.09—2014.06 厦门大学博士（硕博连读）
2005.09—2009.07 江西师范大学学士（本科）
● 研究兴趣、领域：
植物资源学和天然产物化学（植物天然产物活性成分分析和开发）、食品科学与分子酶学、有机小分子合成及活性筛选、生态学、细胞生物学。
● 开设的课程：
本科生课程：《植物生物学》、《植物生物学实验》
研究生课程：《植物成分分析》、《植物科学研究进展》
● 代表性论文：
1.Huang, Q., Chai, W. M.,^*Ma, Z. Y., Ou-Yang, C., Wei, Q. M., Song, S., ... & Peng, Y. Y. (2019). Inhibition of α-glucosidase activity and non-enzymatic glycation by tannic acid: Inhibitory activity and molecular mechanism. International journal of biological macromolecules,141，358-368. (SCI二区，IF=4.784)
2.Chai, W., Ou-Yang, C., Ma, Z., Song, S., Huang, Q., Wei, Q., & Peng, Y. (2019). Anti-α-glucosidase and antityrosinase activity of condensed tannins from the bark of Clausena lansium (Lour.) Skeels with antiproliferative and apoptotic properties in B16 mouse melanoma cells. Process Biochemistry.(SCI三区，IF=2.883)
3.Chai, W. M.,^*Wei, Q., Deng, W., Zheng, Y. , Chen, X., Huang, Q., Ou-Yang, C. and Peng, Y. Y. (2019).Anti-melanogenesis property of condensed tannins from Vigna angularis seed with potent antioxidant and DNA damage protection activities. Food function, 10(1), 99-111. (SCI一区，IF= 3.241)
4.Lin, M. Z., Chai, W. M.,^*Zheng, Y. L., Huang, Q., Ou-Yang, C. (2019). Inhibitory kinetics and mechanism of rifampicin on α-glucosidase: Insights from spectroscopic and molecular docking analyses. International journal of biological macromolecules,122,1244-1252.(SCI二区，IF=4.784)
5.Chai, W. M.,^* Huang, Q., Lin, M. Z., Ou-Yang, C., Huang, W. Y., Wang, Y. X., Xu, K. L., Feng, H. L. (2018). Condensed tannins from longan bark as inhibitor of tyrosinase: structure, activity, and mechanism.Journal of agricultural and food chemistry, 66(4), 908-917. (SCI一区，IF=3.571)
6.Chai, W. M.,^*Ou-Yang, C., Huang, Q., Lin, M. Z., Wang, Y. X., Xu, K. L., (2018).Huang, W. Y., Pan, D. D. Antityrosinase and antioxidant properties of mung bean seed proanthocyanidins: Novel insights into the inhibitory mechanism. Food chemistry, 260, 27–36. (SCI二区TOP，IF=5.399)
7.Lin, M. Z., Chai, W. M.,^*Ou-Yang, C., Huang, Q., Xu, X. H., Peng, Y. Y. (2018).Antityrosinase mechanism of omeprazole and its application on the preservation of fresh-cut Fuji apple. International journal of biological macromolecules,117, 538-545. (SCI二区，IF=4.784)
8.Chai, W. M.,^* Lin, M. Z., Feng, H. L., Zou, Z. R., Wang, Y. X.(2017). Proanthocyanidins purified from fruit pericarp of Clausena lansium(Lour.) Skeels as efficient tyrosinase inhibitors: structure evaluation, inhibitory activity and molecular mechanism. Food function,8, 1043-1051. (SCI一区，IF= 3.241)
9.Chai, W. M.,^* Lin, M. Z., Wang, Y. X., Xu, K. L., Huang, W. Y., Pan, D. D., Zou Z R, & Peng, Y. Y. (2017).Inhibition of tyrosinase by cherimoya pericarp proanthocyanidins: Structural characterization, inhibitory activity and mechanism. Food research international,100,731-739. (SCI二区，IF=3.579)
10.Chai, W. M.,^* Lin, M. Z., Song, F. J., Wang, Y. X., Xu, K. L., Huang, J. X., Fu, J. P., & Peng, Y. Y. (2017).Rifampicin as a novel tyrosinase inhibitor: Inhibitory activity and mechanism. International journal of biological macromolecules, 102, 425-430. (SCI二区，IF=4.784)
11.Wang, R., Chai, W. M.,^*Yang, Q., Wei, M. K., Peng, Y. Y. (2016).2-(4-Fluorophenyl)-quinazolin-4 (3H)-one as a novel tyrosinase inhibitor: Synthesis, inhibitory activity, and mechanism. Bioorganic & medicinal chemistry, 24(19), 4620-4625. (IF=2.9)
12.Wei, M. K., Chai W M,^*Wang, R., Yang, Q., Deng, Z., Peng, Y. Y.(2016). Quinazolinone derivatives: synthesis and comparison of inhibitory mechanisms on α-glucosidase. Bioorganic & medicinal chemistry.25(4), 1303–1308 (IF=2.9)
13.Chai, W. M.,^*Wei, M. K., Wang, R., Deng, R. G., Zou, Z. R., Peng, Y. Y. (2015). Avocado proanthocyanidins as source of tyrosinase inhibitors: structure characterization, inhibitory activity and mechanism. Journal of agricultural and food chemistry,63(33), 7381–7387. (SCI一区，IF=3.571)
14.Chai, W. M.,Shi, Y, Feng, H. L., Xu, L., Xiang, Z. H., Gao, Y. S., Chen, Q. X.^*(2014).Structure characterization and anti-tyrosinase mechanism of polymeric proanthocyanidins fractionated from kiwifruit pericarp. Journal of agricultural and food chemistry,62(27), 6382-6389. (SCI一区，IF=3.571)
15.Chai, W. M.,Chen, C. M., Gao, Y. S., Feng, H. L., Ding, Y. M., Shi, Y., Zhou, H. T., Chen, Q. X.^*(2014).Structural analysis of proanthocyanidins isolated from fruit stone of Chinese hawthorn with potent antityrosinase and antioxidant activity. Journal of agricultural and food chemistry, 62(1), 123–129. (SCI一区，IF=3.571)
16.Chai, W. M.,Liu, X.,Hu, Y. H., Feng, H. L., Jia, Y. L., Guo, Y. J., Zhou, H. T.^*, Chen, Q. X.^*(2013).Antityrosinase and antimicrobial activities of furfuryl alcohol, furfural and furoic acid.International journal of biological macromolecules, 57, 151-155. (SCI二区，IF=4.784)
17.Chai, W. M., Shi, Y., Feng, H. L., Qiu, L., Zhou, H. C., Deng, Z. W., Yan, C. L.^*, Chen, Q. X.^*(2012).NMR, HPLC-ESI-MS, and MALDI-TOF MS analysis of condensed tannins from Delonix regiaand their bioactivities. Journal of agricultural and food chemistry, 60 (19), 5013-5022. (SCI一区，IF=3.57)
● 科研项目：
国家自然科学基金青年项目：龙眼（Dimocarpus longanLour.）单宁分离鉴定与抗酪氨酸酶机理研究 主持
江西省自然科学基金青年重点项目：MALDI-TOF MS和UPLC-MS/MS指导分离壳斗科植物单宁（tannins）及其抗酪氨酸酶机制研究 主持
江西省自然科学基金青年项目：黄皮原花色素分离纯化、结构分析与抗α－葡萄糖苷酶机制研究 主持
● 荣誉、奖励及参加学术团体的情况：
获厦门市科技进步二等奖、福建省优秀论文三等奖
指导挑战杯省二等奖、指导全国生命科学大赛优胜奖
中国生物化学与分子生物学会会员
江西省植物学会会员
● 联系方式：
地址：生命科学学院方荫楼3区W351室
E-mail：@qq.com