袁涛 博士

教授，博士生、硕士生导师
国家海外高层次人才引进计划
江西省“双千计划”创新领军人才
● 学习、工作经历：
2019.4至今 江西师范大学，生命科学学院，教授
2014.6-2019.3 中国科学院新疆理化技术研究所，研究员
2010.8-2014.5 美国罗德岛大学，药学院，博士后
2009.7-2010.7 中国科学院上海药物研究所，助理研究员
2006.9-2009.7 中国科学院上海药物研究所，博士学位，药物化学
2003.9-2006.7 沈阳药科大学，硕士学位，天然药物化学
1999.9-2003.7 江西中医药大学，学士学位，药学
●研究兴趣、领域：
1、道地药材（中药、民族药）药效物质基础研究；
2、天然产物中小分子药物先导化合物发现优化；
3、植物功能性食品研究与开发。
●开设的课程：
本科生课程：药物常识，植物分类；
研究生课程：天然化合物波谱解析
● 近5年代表性论文（通讯作者）：
2021：
Hao Cui,Xinying Zhu,Zhaoguang Wang,Jianping Fang, and Tao Yuan*.A Purified GlucomannanOligosaccharide from Amorphophallus konjac ImprovesColonic MucosalBarrier Function viaEnhancingButyrateProductionandHistone Protein H3 and H4 Acetylation. Journal of Natural Products2021, 84, 427-435.
Jie Gao, Yu Chen, Wei Liu, Yushuang Liu, Miaomiao Li, Guangying Chen, Tao Yuan*. Applanhydrides A and B, lanostane triterpenoids with unprecedented seven-membered cyclo-anhydride in ring C fromGanoderma applanatum. Tetrahedron2021, 79, 131839.
Wei Liu, Jie Gao, Miaomiao Li, Haji Akber Aisa,* Tao Yuan*. Tirucallane triterpenoids from the mastic (Pistacia lentiscus) and their anti-inflammatory and cytotoxic activities.Phytochemistry2021, 182, 112596.
2020：
Yushuang Liu, Lu Zhang, Jingjing Xue, Kaibo Wang, Huiming Hua, Tao Yuan*. Norcolocynthenins A and B, two cucurbitane 3-nor-triterpenoids from Citrullus colocynthisand their cytotoxicity. Bioorganic Chemistry2020, 101, 104045.
Lu Zhang, Wen-na Zhou, Zong-cai Tu,* Si-hang Yang, Liang Xu, and Tao Yuan*. Influence of Hydroxyl Substitution on the Suppression of Flavonol in Harmful Glycation Product Formation and the Inhibition Mechanism Revealed by Spectroscopy and Mass Spectrometry. Journal of Agricultural and Food Chemistry 2020, 68, 8263-8273.
Huijun Xie, Xiaoyu Chen, Miaomiao Li, Haji Akber Aisa, Tao Yuan*. Angustifolinoid B, a flavonoid glycoside dimer with cyclobutane from Elaeagnus angustifoliaflowers. Tetrahedron Lett.2020, 61, 151946.
Yu Chen, Jie Gao, Qibin Chen, Wei Liu, Yanru Qi, Haji Akber Aisa and Tao Yuan*. Applanaic acids A?C, three new highly oxygenated lanostane triterpenoids from the fruiting bodies of Ganoderma applanatum. Natural ProductResearch2020, doi.org/10.1080/**.2020.**.
2019：
LiJia, Lu Zhang, Yun-hua Ye,* Jin-lin Li, Mingyang Cong, and Tao Yuan*. Effect and mechanism of Elaeagnus angustifolia flower and its major flavonoid tiliroside on inhibiting non-enzymatic glycosylation. Journal of Agricultural and Food Chemistry 2019, 67, 13960-13968.
Yanru Qi, Wei Liu, Yu Chen, Ming Guan, Tao Yuan*.Euphatexols A and B, two unusual euphane triterpenoids from the latex ofEuphorbia resinifera. Tetrahedron Lett.2019, 60, 151303.
Qosimjon Khalilov, Liya Li, Yushuang Liu,Wei Liu, Sodik Numonov, Haji Akber Aisa*, Tao Yuan*.Brassinosteroid analogues from the fruiting bodies of Laetiporus sulphureusand their anti-inflammatory activity. Steroids2019, 151, 108468.
Lu Zhang, Yu Lu, Yun-hua Ye*, Si-hang Yang, Zong-cai Tu, Juan Chen, Hui Wang, Hong-hong Wang, andTao Yuan*. Insights into the Mechanism of Quercetin against BSA-Fructose Glycation by Spectroscopy and High Resolution Mass Spectrometry: Effect on Physicochemical Properties.Journal of Agricultural and Food Chemistry 2019,67, 236-246.
Qosimjon Khalilov, Liya Li, Yushuang Liu,Zeynep Tohtahon,Xiaoyu Chen, Haji Akber Aisa and Tao Yuan*. Piptolinic acids F?J, five new lanostane-type triterpenoids from Piptoporus betulinus. Natural ProductResearch2019, 33,3044-3051.
2018：
Yushuang Liu, Guangying Chen, Xiaoyu Chen, Shi-Xin Chen, Li-She Gan, Tao Yuan*. Colocynthenins A-D, Ring-A seco-cucurbitane triterpenoids from the fruits of Citrullus colocynthis. Journal of Natural Products2018, 81, 2115-2119.
Xiaoyu Chen, Yushuang Liu, Guangying Chen, Chi Gong, Shengge Li, Huiming Hua, Tao Yuan*. Angustifolinoid A, a macrocyclic flavonoid glycoside from Elaeagnus angustifoliaflowers. Tetrahedron Letters2018, 59, 2610?2613.
Jianxin Han, Sheng-Tong Niu,Yushuang Liu,Lishe Gan, Tianfu wang,Chong-Dao Lu,* and Tao Yuan*. Robustanoids A and B, two novel pyrrolo[2,3-b]indole alkaloids from Coffea canephora: isolation and total synthesis. Organic Chemistry Frontiers2018,5, 586?589.
Yushuang Liu, Jingjing Xue, Jianxin Han,Huiming Hua, Tao Yuan*.Polyacetylenes from the florets of Carthamus tinctorius and their cytotoxicity. Phytochemistry Letters2018, 23, 168?171.
2017：
Zeynep Tohtahon, Jingjing Xue, Jianxin Han,Yushuang Liu,Huiming Hua and Tao Yuan^*. Cytotoxic Lanostane Triterpenoids from the Fruiting Bodies of Piptoporus betulinus.Phytochemistry2017, 143, 98-103.
Zeynep Tohtahon, Lu Zhang, Jianxin Han,Xing Xie, Zongcai Tu,^*Tao Yuan^*. Extraction optimization, structural characterization and bio-activity evaluation of triterpenoids from hawthorn (Crataegus cuneata) fruits. Journal of Food Biochemistry2017,e12377.
Qing Ren, Xue-Ying Lu, Jian-Xin Han, Haji Akber Aisa, Tao Yuan*. Triterpenoids and phenolics from the fruiting bodies of Inonotus hispidus and their activations of melanogenesis and tyrosinase. Chinese Chemical Letters2017, 28, 1052-1056.
● 科研项目：
国家自然科学基金（**，U**）；
新疆维吾尔自治区重点研发计划项目（2016B03038-3）
●荣誉、奖励及参加学术团体的情况：
1、《中国中药杂志》编委；
2、《天然产物研究与开发》青年编委；
3、中国菌物学会药用真菌委员会副主任；
4、中国民族医药学会药用资源分会副会长；
5、2018年江西省自然科学奖三等奖；
6、中国青年科技工作者协会理事。
●联系方式：
地址：江西师范大学瑶湖校区 方荫楼3316
电话：
E-mail：tyuan@jxnu.edu.cn