Becki Yi KUANG
曠怡
PhD in Chemistry
Brandeis University, 2013

Assistant Professor
Department of Chemical and Biological Engineering



(852) 3469 2617
kekuang@ust.hk
Room 5578
Personal Web

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Google Scholar
lOKGlxAAAAAJ

ResearcherID
Q-4197-2017

Scopus ID
8850494400




Research Interest Publications Projects Teaching Assignment RPG Supervision Space used




Research Interest

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Synthetic biology
Biomaterials
Biomedical engineering (BME)



Publications

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All Years 41 2022 0 2021 0 2020 1 2019 0 2018 1 2017 2 2016 37

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2020 1

N¹-Methylpseudouridine substitution enhances the performance of synthetic mRNA switches in cells
Nucleic Acids Research, v. 48, (6), April 2020, p. e35
Parr, Callum J.C.; Wada, Shunsuke; Kotake, Kenjiro; Kameda, Shigetoshi; Matsuura, Satoshi; Sakashita, Souhei; Park, Soyoung; Sugiyaman, Hiroshi; Kuang, Becki Yi; Saito, Hirohide Article

2018 1

Synthetic RNA-based Logic Computation in Mammalian Cells
Nature Communications, v. 9, (1), November 2018, article number 4847
Matsuura, Satoshi; Ono, Hiroki; Kawasaki, Shunsuke; Kuang, Yi; Fujita, Yoshihiko; Saito, Hirohide Article

2017 2

Efficient, Selective Removal of Human Pluripotent Stem Cells via Ecto-Alkaline Phosphatase-Mediated Aggregation of Synthetic Peptides
Cell Chemical Biology, v. 24, (6), June 2017, p. 685-694.e4
Kuang, Yi; Miki, Kenji; Parr, Callum J. C.; Hayashi, Karin; Takei, Ikue; Li, Jie; Iwasaki, Mio; Nakagawa, Masato; Yoshida, Yoshinori; Saito, Hirohide Article
In Situ Generated D-peptidic Nanofibrils as Multifaceted Apoptotic Inducers to Target Cancer Cells
Cell Death and Disease, v. 8, (2), 2017, article number e2614
Du, Xuewen; Zhou, Jie; Wang, Huainin; Shi, Junfeng; Kuang, Yi; Zeng, Wu; Yang, Zhimou; Xu, Bing Article

2016 2

MicroRna-302 Switch to Identify and Eliminate Undifferentiated Human Pluripotent Stem Cells
Scientific Reports, v. 6, September 2016, article number 32532
Parr, Callum J.C.; Katayama, Shota; Miki, Kenji; Kuang, Yi; Yoshida, Yoshinori; Morizane, Asuka; Takahashi, Jun B.; Yamanaka, Shinya; Saito, Hirohide Article
Nanonets Collect Cancer Secretome from Pericellular Space
PLoS ONE, v. 11, (4), April 2016, article number e0154126
Zhou, Rong; Kuang, Yi; Zhou, Jie; Du, Xuewen; Li, Jie; Shi, Junfeng; Haburcak, Richard; Xu, Bing Article

2015 1

Enzyme-Instructed Intracellular Molecular Self-Assembly to Boost Activity of Cisplatin against Drug-Resistant Ovarian Cancer Cells
Angewandte Chemie - International Edition, v. 54, (45), November 2015, p. 13307-13311
Li, Jie; Kuang, Yi; Shi, Junfeng; Zhou, Jie; Medina, Jamie E.; Zhou, Rong; Yuan, Dan; Yang, Cuihong; Wang, Huaimin; Yang, Zhimou; Liu, Jianfeng; Dinulescu, Daniela M.; Xu, Bing Article

2014 5

Pericellular Hydrogel/Nanonets Inhibit Cancer Cells
Angewandte Chemie - International Edition, v. 53, (31), July 2014, p. 8104-8107
Kuang, Yi; Shi, Junfeng; Li, Jie; Yuan, Dan; Alberti, Kyle A.; Xu, Qiaobing; Xu, Bing Article
Prion-like Nanofibrils of Small Molecules (PriSM) Selectively Inhibit Cancer Cells by Impeding Cytoskeleton Dynamics
Journal of Biological Chemistry, v. 289, (42), October 2014, p. 29208-29218
Kuang, Yi; Long, Marcus J. C.; Zhou, Jie; Shi, Junfeng; Gao, Yuan; Xu, Chen; Hedstrom, Lizbeth; Xu, Bing Article
Supramolecular Nanofibrils Inhibit Cancer Progression In Vitro and In Vivo
Advanced Healthcare Materials, v. 3, (8), August 2014, p. 1217-1221
Kuang, Yi; Du, Xuewen; Zhou, Jie; Xu, Bing Article
The First Supramolecular Peptidic Hydrogelator Containing Taurine
Chemical Communications, v. 50, (21), March 2014, p. 2772-2774
Kuang, Yi; Gao, Yuan; Shi, Junfeng; Li, Jie; Xu, Bing Article
Biocompatibility of Hydrogelators Based on Small Peptide Derivatives
Hydrogels in Cell-Based Therapies / Editor(s): Che J Connon, Ian W Hamley. Cambridge, United Kingdom : Royal Society Of Chemistry, 2014, p. 31-47
Kuang, Yi; Zhou, Ning; Xu, Bing Book chapter

2013 10

A Redox Responsive, Fluorescent Supramolecular Metallohydrogel Consists of Nanofibers With Single-molecule Width
Journal of the American Chemical Society, v. 135, (13), April 2013, p. 5008-5011
Zhang, Ye; Zhang, Bei; Kuang, Yi; Gao, Yuan; Shi, Junfeng; Zhang, Xi Xiang; Xu, Bing Article
Active Cross-linkers That Lead to Active Gels
Angewandte Chemie - International Edition, v. 52, (44), October 2013, p. 11494-11498
Zhang, Ye; Zhou, Ning; Akella, Sathish V.; Kuang, Yi; Kim, Dongshin; Schwartz, Alyssa; Bezpalko, Mark W.; Foxman, Bruce M.; Fraden, Seth; Epstein, Irving R.; Xu, Bing Article
D-Amino Acids Boost the Selectivity and Confer Supramolecular Hydrogels of a Nonsteroidal Anti-Inflammatory Drug (NSAID)
Journal of the American Chemical Society, v. 135, (2), January 2013, p. 542-545
Li, Jiayang; Kuang, Yi; Gao, Yuan; Du, Xuewen; Shi, Junfeng; Xu, Bing Article
Dephosphorylation of D-peptide Derivatives to Form Biofunctional, Supramolecular Nanofibers/hydrogels and Their Potential Applications for Intracellular Imaging and Intratumoral Chemotherapy
Journal of the American Chemical Society, v. 135, (26), July 2013, p. 9907-9914
Li, Jiayang; Gao, Yuan; Kuang, Yi; Shi, Junfeng; Du, Xuewen; Zhou, Jie; Wang, Huaimin; Yang, Zhimou; Xu, Bing Article
Disruption of the Dynamics of Microtubules and Selective Inhibition of Glioblastoma Cells by Nanofibers of Small Hydrophobic Molecules
Angewandte Chemie - International Edition, v. 52, (27), July 2013, p. 6944-6948
Kuang, Yi; Xu, Bing Article
Imaging Self-assembly Dependent Spatial Distribution of Small Molecules in Cellular Environment
Langmuir, v. 29, (49), December 2013, p. 15191-15200
Gao, Yuan; Kuang, Yi; Du, Xuewen; Zhou, Jie; Chandran, Preethi; Horkay, Ferenc; Xu, Bing Article
Interactions Between Cellular Proteins and Morphologically Different Nanoscale Aggregates of Small Molecules
RSC Advances, v. 3, (21), June 2013, p. 7704-7707
Kuang, Yi; Yuan, Dan; Zhang, Ye; Kao, Anita; Du, Xuewen; Xu, Bing Article
Probing Nanoscale Self-Assembly of Nonfluorescent Small Molecules inside Live Mammalian Cells
ACS Nano, v. 7, (10), October 2013, p. 9055-9063
Gao, Yuan; Berciu, Cristina; Kuang, Yi; Shi, Junfeng; Nicastro, Daniela; Xu, Bing Article
Self-Delivery Multifunctional Anti-HIV Hydrogels for Sustained Release
Advanced Healthcare Materials, v. 2, (12), December 2013, p. 1586-1590
Li, Jiayang; Li, Xinming; Kuang, Yi; Gao, Yuan; Du, Xuewen; Shi, Junfeng; Xu, Bing Article
The Conjugation of Nonsteroidal Anti-inflammatory Drugs (NSAID) to Small Peptides for Generating Multifunctional Supramolecular Nanofibers/hydrogels
Beilstein Journal of Organic Chemistry, v. 9, May 2013, p. 908-917
Li, Jiayang; Kuang, Yi; Shi, Junfeng; Gao, Yuan; Zhou, Jie; Xu, Bing Article

2012 5

“Molecular Trinity” for Soft Nanomaterials: Integrating Nucleobases, Amino Acids, and Glycosides to Construct Multifunctional Hydrogelators
Soft Matter, v. 8, (10), March 2012, p. 2801-2806
Li, Xinming; Kuang, Yi; Xu, Bing Article
Catalytic Dephosphorylation of Adenosine Monophosphate (AMP) to Form Supramolecular Nanofibers/hydrogels
Chemical Communications, v. 48, (15), February 2012, p. 2098-2100
Du, Xuewen; Li, Junfeng; Gao, Yuan; Kuang, Yi; Xu, Bing Article
Post-self-assembly Cross-linking of Molecular Nanofibers for Oscillatory Hydrogels
Langmuir, v. 28, (6), February 2012, p. 3063-3066
Zhang, Ye; Li, Ning; Delgado, Jorge; Gao, Yuan; Kuang, Yi; Fraden, Seth; Epstein, Irving R.; Xu, Bing Article
Supramolecular Hydrogel of Kanamycin Selectively Sequesters 16S rRNA
Chemical Communications, v. 48, (74), September 2012, p. 9257-9259
Yang, Zhimou; Kuang, Yi; Li, Xinming; Zhou, Ning; Zhang, Ye; Xu, Bing Article
Supramolecular Hydrogels Formed by the Conjugates of Nucleobases, Arg-Gly-Asp (RGD) Peptides, and Glucosamine
Soft Matter, v. 8, (28), July 2012, p. 7402-7404
Li, Xinming; Du, Xuewen; Gao, Yuan; Shi, Junfeng; Kuang, Yi; Xu, Bing Article

2011 5

Multifunctional, Biocompatible Supramolecular Hydrogelators Consist Only of Nucleobase, Amino Acid, and Glycoside
Journal of the American Chemical Society, v. 133, (43), November 2011, p. 17513-17518
Li, Xinming; Kuang, Yi; Shi, Junfeng; Gao, Yuan; Lin, Hsin-Chieh; Xu, Bing Article
Supramolecular Hydrogelators of N-terminated Dipeptides Selectively Inhibit Cancer Cells
Chemical Communications, v. 47, (47), December 2011, p. 12625-12627
Kuang, Yi; Gao, Yuan; Xu, Bing Article
Supramolecular Hydrogels Based on the Epitope of Potassium Ion Channels
Chemical Communications, v. 47, (31), August 2011, p. 8772-8774
Kuang, Yi; Gao, Yuan; Shi, Junfeng; Lin, Hsin-Chieh; Xu, Bing Article
Supramolecular Nanofibers and Hydrogels of Nucleopeptides
Angewandte Chemie - International Edition, v. 50, (40), September 2011, p. 9365-9369
Li, Xinming; Kuang, Yi; Lin, Hsin-Chieh; Gao, Yuan; Shi, Junfeng; Xu, Bing Article
Versatile Small-molecule Motifs for Self-assembly in Water and the Formation of Biofunctional Supramolecular Hydrogels
Langmuir, v. 27, (2), January 2011, p. 529-537
Zhang, Ye; Kuang, Yi; Gao, Yuan; Xu, Bing Article

2010 4

Aromatic-Aromatic Interactions Induce the Self-Assembly of Pentapeptidic Derivatives in Water To Form Nanofibers and Supramolecular Hydrogels
Journal of the American Chemical Society, v. 132, (8), February 2010, p. 2719-2728
Ma, Nlung; Kuang, Yi; Gao, Yuan; Zhang, Yan; Gao, Ping; Xu, Bing Article
Enzymatic Formation of a Photoresponsive Supramolecular Hydrogel
Chemical Communications, v. 46, (29), 2010, p. 5364-5366
Li, Xinming; Gao, Yuan; Kuang, Yi; Xu, Bing Article
Enzyme-instructed Self-assembly of Peptide Derivatives to Form Nanofibers and Hydrogels
Biopolymers, v. 94, (1), January 2010, p. 19-31
Gao, Yuan; Yang, Zhimou; Kuang, Yi; Ma, Man-Lung; Li, Jiayang; Zhao, Fan; Xu, Bing Article
Molecular Nanofibers of Olsalazine Form Supramolecular Hydrogels for Reductive Release of an Anti-inflammatory Agent
Journal of the American Chemical Society, v. 132, (50), December 2010, p. 17707-17709
Li, Xinming; Li, Jiayang; Gao, Yuan; Kuang, Yi; Shi, Junfeng; Xu, Bing Article

2009 2

Enzyme-Instructed Molecular Self-assembly Confers Nanofibers and a Supramolecular Hydrogel of Taxol Derivative
Journal of the American Chemical Society, v. 131, (38), September 2009, p. 13576-13577
Gao, Yuan; Kuang, Yi; Guo, Zufeng; Guo, Zhihong; Krauss, Isaac J.; Xu, Bing Article
Supramolecular Hydrogel of a D-Amino Acid Dipeptide for Controlled Drug Release in Vivo
Langmuir, v. 25, (15), August 2009, p. 8419-8422
Liang, Gaolin; Yang, Zhimou; Zhang, Rongjun; Li, Lihua; Fan, Yijun; Kuang, Yi; Gao, Yuan; Wang, Ting; Lu, W. William; Xu, Bing Article

2008 1

Multifunctional Yolk-shell Nanoparticles: A Potential MRI Contrast and Anticancer Agent
Journal of the American Chemical Society, v. 130, (35), September 2008, p. 11828-11833
Gao, Jinhao; Liang, Gaolin; Cheung, Jerry S.; Pan, Yue; Kuang, Yi; Zhao, Fan; Zhang, Bei; Zhang, Xixiang; Wu, Ed X.; Xu, Bing Article

2007 2

FePt@CoS2 Yolk-shell Nanocrystals as a Potent Agent to Kill HeLa Cells
Journal of the American Chemical Society, v. 129, (5), February 2007, p. 1428-1433
Gao, Jinhao; Liang, Gaolin; Zhang, Bei; Kuang, Yi; Zhang, Xixiang; Xu, Bing Article
Using Congo Red to Report Intracellular Hydrogelation Resulted From Self-assembly of Small Molecules
Chemical communications, (40), 2007, p. 4096-4098
Liang, Gaolin; Xu, Keming; Li, Lihua; Wang, Ling; Kuang, Yi; Yang, Zhimou; Xu, Bing Article


Expand All Collapse All


Article 1

N¹-Methylpseudouridine substitution enhances the performance of synthetic mRNA switches in cells
Nucleic Acids Research, v. 48, (6), April 2020, p. e35
Parr, Callum J.C.; Wada, Shunsuke; Kotake, Kenjiro; Kameda, Shigetoshi; Matsuura, Satoshi; Sakashita, Souhei; Park, Soyoung; Sugiyaman, Hiroshi; Kuang, Becki Yi; Saito, Hirohide


Expand All Collapse All


Article 1

Synthetic RNA-based Logic Computation in Mammalian Cells
Nature Communications, v. 9, (1), November 2018, article number 4847
Matsuura, Satoshi; Ono, Hiroki; Kawasaki, Shunsuke; Kuang, Yi; Fujita, Yoshihiko; Saito, Hirohide


Expand All Collapse All


Article 2

Efficient, Selective Removal of Human Pluripotent Stem Cells via Ecto-Alkaline Phosphatase-Mediated Aggregation of Synthetic Peptides
Cell Chemical Biology, v. 24, (6), June 2017, p. 685-694.e4
Kuang, Yi; Miki, Kenji; Parr, Callum J. C.; Hayashi, Karin; Takei, Ikue; Li, Jie; Iwasaki, Mio; Nakagawa, Masato; Yoshida, Yoshinori; Saito, Hirohide
In Situ Generated D-peptidic Nanofibrils as Multifaceted Apoptotic Inducers to Target Cancer Cells
Cell Death and Disease, v. 8, (2), 2017, article number e2614
Du, Xuewen; Zhou, Jie; Wang, Huainin; Shi, Junfeng; Kuang, Yi; Zeng, Wu; Yang, Zhimou; Xu, Bing


Expand All Collapse All


Article 2

MicroRna-302 Switch to Identify and Eliminate Undifferentiated Human Pluripotent Stem Cells
Scientific Reports, v. 6, September 2016, article number 32532
Parr, Callum J.C.; Katayama, Shota; Miki, Kenji; Kuang, Yi; Yoshida, Yoshinori; Morizane, Asuka; Takahashi, Jun B.; Yamanaka, Shinya; Saito, Hirohide
Nanonets Collect Cancer Secretome from Pericellular Space
PLoS ONE, v. 11, (4), April 2016, article number e0154126
Zhou, Rong; Kuang, Yi; Zhou, Jie; Du, Xuewen; Li, Jie; Shi, Junfeng; Haburcak, Richard; Xu, Bing


Expand All Collapse All


Article 1

Enzyme-Instructed Intracellular Molecular Self-Assembly to Boost Activity of Cisplatin against Drug-Resistant Ovarian Cancer Cells
Angewandte Chemie - International Edition, v. 54, (45), November 2015, p. 13307-13311
Li, Jie; Kuang, Yi; Shi, Junfeng; Zhou, Jie; Medina, Jamie E.; Zhou, Rong; Yuan, Dan; Yang, Cuihong; Wang, Huaimin; Yang, Zhimou; Liu, Jianfeng; Dinulescu, Daniela M.; Xu, Bing


Expand All Collapse All


Article 4

Pericellular Hydrogel/Nanonets Inhibit Cancer Cells
Angewandte Chemie - International Edition, v. 53, (31), July 2014, p. 8104-8107
Kuang, Yi; Shi, Junfeng; Li, Jie; Yuan, Dan; Alberti, Kyle A.; Xu, Qiaobing; Xu, Bing
Prion-like Nanofibrils of Small Molecules (PriSM) Selectively Inhibit Cancer Cells by Impeding Cytoskeleton Dynamics
Journal of Biological Chemistry, v. 289, (42), October 2014, p. 29208-29218
Kuang, Yi; Long, Marcus J. C.; Zhou, Jie; Shi, Junfeng; Gao, Yuan; Xu, Chen; Hedstrom, Lizbeth; Xu, Bing
Supramolecular Nanofibrils Inhibit Cancer Progression In Vitro and In Vivo
Advanced Healthcare Materials, v. 3, (8), August 2014, p. 1217-1221
Kuang, Yi; Du, Xuewen; Zhou, Jie; Xu, Bing
The First Supramolecular Peptidic Hydrogelator Containing Taurine
Chemical Communications, v. 50, (21), March 2014, p. 2772-2774
Kuang, Yi; Gao, Yuan; Shi, Junfeng; Li, Jie; Xu, Bing

Book chapter 1

Biocompatibility of Hydrogelators Based on Small Peptide Derivatives
Hydrogels in Cell-Based Therapies / Editor(s): Che J Connon, Ian W Hamley. Cambridge, United Kingdom : Royal Society Of Chemistry, 2014, p. 31-47
Kuang, Yi; Zhou, Ning; Xu, Bing


Expand All Collapse All


Article 10

A Redox Responsive, Fluorescent Supramolecular Metallohydrogel Consists of Nanofibers With Single-molecule Width
Journal of the American Chemical Society, v. 135, (13), April 2013, p. 5008-5011
Zhang, Ye; Zhang, Bei; Kuang, Yi; Gao, Yuan; Shi, Junfeng; Zhang, Xi Xiang; Xu, Bing
Active Cross-linkers That Lead to Active Gels
Angewandte Chemie - International Edition, v. 52, (44), October 2013, p. 11494-11498
Zhang, Ye; Zhou, Ning; Akella, Sathish V.; Kuang, Yi; Kim, Dongshin; Schwartz, Alyssa; Bezpalko, Mark W.; Foxman, Bruce M.; Fraden, Seth; Epstein, Irving R.; Xu, Bing
D-Amino Acids Boost the Selectivity and Confer Supramolecular Hydrogels of a Nonsteroidal Anti-Inflammatory Drug (NSAID)
Journal of the American Chemical Society, v. 135, (2), January 2013, p. 542-545
Li, Jiayang; Kuang, Yi; Gao, Yuan; Du, Xuewen; Shi, Junfeng; Xu, Bing
Dephosphorylation of D-peptide Derivatives to Form Biofunctional, Supramolecular Nanofibers/hydrogels and Their Potential Applications for Intracellular Imaging and Intratumoral Chemotherapy
Journal of the American Chemical Society, v. 135, (26), July 2013, p. 9907-9914
Li, Jiayang; Gao, Yuan; Kuang, Yi; Shi, Junfeng; Du, Xuewen; Zhou, Jie; Wang, Huaimin; Yang, Zhimou; Xu, Bing
Disruption of the Dynamics of Microtubules and Selective Inhibition of Glioblastoma Cells by Nanofibers of Small Hydrophobic Molecules
Angewandte Chemie - International Edition, v. 52, (27), July 2013, p. 6944-6948
Kuang, Yi; Xu, Bing
Imaging Self-assembly Dependent Spatial Distribution of Small Molecules in Cellular Environment
Langmuir, v. 29, (49), December 2013, p. 15191-15200
Gao, Yuan; Kuang, Yi; Du, Xuewen; Zhou, Jie; Chandran, Preethi; Horkay, Ferenc; Xu, Bing
Interactions Between Cellular Proteins and Morphologically Different Nanoscale Aggregates of Small Molecules
RSC Advances, v. 3, (21), June 2013, p. 7704-7707
Kuang, Yi; Yuan, Dan; Zhang, Ye; Kao, Anita; Du, Xuewen; Xu, Bing
Probing Nanoscale Self-Assembly of Nonfluorescent Small Molecules inside Live Mammalian Cells
ACS Nano, v. 7, (10), October 2013, p. 9055-9063
Gao, Yuan; Berciu, Cristina; Kuang, Yi; Shi, Junfeng; Nicastro, Daniela; Xu, Bing
Self-Delivery Multifunctional Anti-HIV Hydrogels for Sustained Release
Advanced Healthcare Materials, v. 2, (12), December 2013, p. 1586-1590
Li, Jiayang; Li, Xinming; Kuang, Yi; Gao, Yuan; Du, Xuewen; Shi, Junfeng; Xu, Bing
The Conjugation of Nonsteroidal Anti-inflammatory Drugs (NSAID) to Small Peptides for Generating Multifunctional Supramolecular Nanofibers/hydrogels
Beilstein Journal of Organic Chemistry, v. 9, May 2013, p. 908-917
Li, Jiayang; Kuang, Yi; Shi, Junfeng; Gao, Yuan; Zhou, Jie; Xu, Bing


Expand All Collapse All


Article 5

“Molecular Trinity” for Soft Nanomaterials: Integrating Nucleobases, Amino Acids, and Glycosides to Construct Multifunctional Hydrogelators
Soft Matter, v. 8, (10), March 2012, p. 2801-2806
Li, Xinming; Kuang, Yi; Xu, Bing
Catalytic Dephosphorylation of Adenosine Monophosphate (AMP) to Form Supramolecular Nanofibers/hydrogels
Chemical Communications, v. 48, (15), February 2012, p. 2098-2100
Du, Xuewen; Li, Junfeng; Gao, Yuan; Kuang, Yi; Xu, Bing
Post-self-assembly Cross-linking of Molecular Nanofibers for Oscillatory Hydrogels
Langmuir, v. 28, (6), February 2012, p. 3063-3066
Zhang, Ye; Li, Ning; Delgado, Jorge; Gao, Yuan; Kuang, Yi; Fraden, Seth; Epstein, Irving R.; Xu, Bing
Supramolecular Hydrogel of Kanamycin Selectively Sequesters 16S rRNA
Chemical Communications, v. 48, (74), September 2012, p. 9257-9259
Yang, Zhimou; Kuang, Yi; Li, Xinming; Zhou, Ning; Zhang, Ye; Xu, Bing
Supramolecular Hydrogels Formed by the Conjugates of Nucleobases, Arg-Gly-Asp (RGD) Peptides, and Glucosamine
Soft Matter, v. 8, (28), July 2012, p. 7402-7404
Li, Xinming; Du, Xuewen; Gao, Yuan; Shi, Junfeng; Kuang, Yi; Xu, Bing


Expand All Collapse All


Article 5

Multifunctional, Biocompatible Supramolecular Hydrogelators Consist Only of Nucleobase, Amino Acid, and Glycoside
Journal of the American Chemical Society, v. 133, (43), November 2011, p. 17513-17518
Li, Xinming; Kuang, Yi; Shi, Junfeng; Gao, Yuan; Lin, Hsin-Chieh; Xu, Bing
Supramolecular Hydrogelators of N-terminated Dipeptides Selectively Inhibit Cancer Cells
Chemical Communications, v. 47, (47), December 2011, p. 12625-12627
Kuang, Yi; Gao, Yuan; Xu, Bing
Supramolecular Hydrogels Based on the Epitope of Potassium Ion Channels
Chemical Communications, v. 47, (31), August 2011, p. 8772-8774
Kuang, Yi; Gao, Yuan; Shi, Junfeng; Lin, Hsin-Chieh; Xu, Bing
Supramolecular Nanofibers and Hydrogels of Nucleopeptides
Angewandte Chemie - International Edition, v. 50, (40), September 2011, p. 9365-9369
Li, Xinming; Kuang, Yi; Lin, Hsin-Chieh; Gao, Yuan; Shi, Junfeng; Xu, Bing
Versatile Small-molecule Motifs for Self-assembly in Water and the Formation of Biofunctional Supramolecular Hydrogels
Langmuir, v. 27, (2), January 2011, p. 529-537
Zhang, Ye; Kuang, Yi; Gao, Yuan; Xu, Bing


Expand All Collapse All


Article 4

Aromatic-Aromatic Interactions Induce the Self-Assembly of Pentapeptidic Derivatives in Water To Form Nanofibers and Supramolecular Hydrogels
Journal of the American Chemical Society, v. 132, (8), February 2010, p. 2719-2728
Ma, Nlung; Kuang, Yi; Gao, Yuan; Zhang, Yan; Gao, Ping; Xu, Bing
Enzymatic Formation of a Photoresponsive Supramolecular Hydrogel
Chemical Communications, v. 46, (29), 2010, p. 5364-5366
Li, Xinming; Gao, Yuan; Kuang, Yi; Xu, Bing
Enzyme-instructed Self-assembly of Peptide Derivatives to Form Nanofibers and Hydrogels
Biopolymers, v. 94, (1), January 2010, p. 19-31
Gao, Yuan; Yang, Zhimou; Kuang, Yi; Ma, Man-Lung; Li, Jiayang; Zhao, Fan; Xu, Bing
Molecular Nanofibers of Olsalazine Form Supramolecular Hydrogels for Reductive Release of an Anti-inflammatory Agent
Journal of the American Chemical Society, v. 132, (50), December 2010, p. 17707-17709
Li, Xinming; Li, Jiayang; Gao, Yuan; Kuang, Yi; Shi, Junfeng; Xu, Bing


Expand All Collapse All


Article 2

Enzyme-Instructed Molecular Self-assembly Confers Nanofibers and a Supramolecular Hydrogel of Taxol Derivative
Journal of the American Chemical Society, v. 131, (38), September 2009, p. 13576-13577
Gao, Yuan; Kuang, Yi; Guo, Zufeng; Guo, Zhihong; Krauss, Isaac J.; Xu, Bing
Supramolecular Hydrogel of a D-Amino Acid Dipeptide for Controlled Drug Release in Vivo
Langmuir, v. 25, (15), August 2009, p. 8419-8422
Liang, Gaolin; Yang, Zhimou; Zhang, Rongjun; Li, Lihua; Fan, Yijun; Kuang, Yi; Gao, Yuan; Wang, Ting; Lu, W. William; Xu, Bing


Expand All Collapse All


Article 1

Multifunctional Yolk-shell Nanoparticles: A Potential MRI Contrast and Anticancer Agent
Journal of the American Chemical Society, v. 130, (35), September 2008, p. 11828-11833
Gao, Jinhao; Liang, Gaolin; Cheung, Jerry S.; Pan, Yue; Kuang, Yi; Zhao, Fan; Zhang, Bei; Zhang, Xixiang; Wu, Ed X.; Xu, Bing


Expand All Collapse All


Article 2

FePt@CoS2 Yolk-shell Nanocrystals as a Potent Agent to Kill HeLa Cells
Journal of the American Chemical Society, v. 129, (5), February 2007, p. 1428-1433
Gao, Jinhao; Liang, Gaolin; Zhang, Bei; Kuang, Yi; Zhang, Xixiang; Xu, Bing
Using Congo Red to Report Intracellular Hydrogelation Resulted From Self-assembly of Small Molecules
Chemical communications, (40), 2007, p. 4096-4098
Liang, Gaolin; Xu, Keming; Li, Lihua; Wang, Ling; Kuang, Yi; Yang, Zhimou; Xu, Bing


Expand All Collapse All


2016 2

MicroRna-302 Switch to Identify and Eliminate Undifferentiated Human Pluripotent Stem Cells
Scientific Reports, v. 6, September 2016, article number 32532
Parr, Callum J.C.; Katayama, Shota; Miki, Kenji; Kuang, Yi; Yoshida, Yoshinori; Morizane, Asuka; Takahashi, Jun B.; Yamanaka, Shinya; Saito, Hirohide Article
Nanonets Collect Cancer Secretome from Pericellular Space
PLoS ONE, v. 11, (4), April 2016, article number e0154126
Zhou, Rong; Kuang, Yi; Zhou, Jie; Du, Xuewen; Li, Jie; Shi, Junfeng; Haburcak, Richard; Xu, Bing Article

2015 1

Enzyme-Instructed Intracellular Molecular Self-Assembly to Boost Activity of Cisplatin against Drug-Resistant Ovarian Cancer Cells
Angewandte Chemie - International Edition, v. 54, (45), November 2015, p. 13307-13311
Li, Jie; Kuang, Yi; Shi, Junfeng; Zhou, Jie; Medina, Jamie E.; Zhou, Rong; Yuan, Dan; Yang, Cuihong; Wang, Huaimin; Yang, Zhimou; Liu, Jianfeng; Dinulescu, Daniela M.; Xu, Bing Article

2014 5

Pericellular Hydrogel/Nanonets Inhibit Cancer Cells
Angewandte Chemie - International Edition, v. 53, (31), July 2014, p. 8104-8107
Kuang, Yi; Shi, Junfeng; Li, Jie; Yuan, Dan; Alberti, Kyle A.; Xu, Qiaobing; Xu, Bing Article
Prion-like Nanofibrils of Small Molecules (PriSM) Selectively Inhibit Cancer Cells by Impeding Cytoskeleton Dynamics
Journal of Biological Chemistry, v. 289, (42), October 2014, p. 29208-29218
Kuang, Yi; Long, Marcus J. C.; Zhou, Jie; Shi, Junfeng; Gao, Yuan; Xu, Chen; Hedstrom, Lizbeth; Xu, Bing Article
Supramolecular Nanofibrils Inhibit Cancer Progression In Vitro and In Vivo
Advanced Healthcare Materials, v. 3, (8), August 2014, p. 1217-1221
Kuang, Yi; Du, Xuewen; Zhou, Jie; Xu, Bing Article
The First Supramolecular Peptidic Hydrogelator Containing Taurine
Chemical Communications, v. 50, (21), March 2014, p. 2772-2774
Kuang, Yi; Gao, Yuan; Shi, Junfeng; Li, Jie; Xu, Bing Article
Biocompatibility of Hydrogelators Based on Small Peptide Derivatives
Hydrogels in Cell-Based Therapies / Editor(s): Che J Connon, Ian W Hamley. Cambridge, United Kingdom : Royal Society Of Chemistry, 2014, p. 31-47
Kuang, Yi; Zhou, Ning; Xu, Bing Book chapter

2013 10

A Redox Responsive, Fluorescent Supramolecular Metallohydrogel Consists of Nanofibers With Single-molecule Width
Journal of the American Chemical Society, v. 135, (13), April 2013, p. 5008-5011
Zhang, Ye; Zhang, Bei; Kuang, Yi; Gao, Yuan; Shi, Junfeng; Zhang, Xi Xiang; Xu, Bing Article
Active Cross-linkers That Lead to Active Gels
Angewandte Chemie - International Edition, v. 52, (44), October 2013, p. 11494-11498
Zhang, Ye; Zhou, Ning; Akella, Sathish V.; Kuang, Yi; Kim, Dongshin; Schwartz, Alyssa; Bezpalko, Mark W.; Foxman, Bruce M.; Fraden, Seth; Epstein, Irving R.; Xu, Bing Article
D-Amino Acids Boost the Selectivity and Confer Supramolecular Hydrogels of a Nonsteroidal Anti-Inflammatory Drug (NSAID)
Journal of the American Chemical Society, v. 135, (2), January 2013, p. 542-545
Li, Jiayang; Kuang, Yi; Gao, Yuan; Du, Xuewen; Shi, Junfeng; Xu, Bing Article
Dephosphorylation of D-peptide Derivatives to Form Biofunctional, Supramolecular Nanofibers/hydrogels and Their Potential Applications for Intracellular Imaging and Intratumoral Chemotherapy
Journal of the American Chemical Society, v. 135, (26), July 2013, p. 9907-9914
Li, Jiayang; Gao, Yuan; Kuang, Yi; Shi, Junfeng; Du, Xuewen; Zhou, Jie; Wang, Huaimin; Yang, Zhimou; Xu, Bing Article
Disruption of the Dynamics of Microtubules and Selective Inhibition of Glioblastoma Cells by Nanofibers of Small Hydrophobic Molecules
Angewandte Chemie - International Edition, v. 52, (27), July 2013, p. 6944-6948
Kuang, Yi; Xu, Bing Article
Imaging Self-assembly Dependent Spatial Distribution of Small Molecules in Cellular Environment
Langmuir, v. 29, (49), December 2013, p. 15191-15200
Gao, Yuan; Kuang, Yi; Du, Xuewen; Zhou, Jie; Chandran, Preethi; Horkay, Ferenc; Xu, Bing Article
Interactions Between Cellular Proteins and Morphologically Different Nanoscale Aggregates of Small Molecules
RSC Advances, v. 3, (21), June 2013, p. 7704-7707
Kuang, Yi; Yuan, Dan; Zhang, Ye; Kao, Anita; Du, Xuewen; Xu, Bing Article
Probing Nanoscale Self-Assembly of Nonfluorescent Small Molecules inside Live Mammalian Cells
ACS Nano, v. 7, (10), October 2013, p. 9055-9063
Gao, Yuan; Berciu, Cristina; Kuang, Yi; Shi, Junfeng; Nicastro, Daniela; Xu, Bing Article
Self-Delivery Multifunctional Anti-HIV Hydrogels for Sustained Release
Advanced Healthcare Materials, v. 2, (12), December 2013, p. 1586-1590
Li, Jiayang; Li, Xinming; Kuang, Yi; Gao, Yuan; Du, Xuewen; Shi, Junfeng; Xu, Bing Article
The Conjugation of Nonsteroidal Anti-inflammatory Drugs (NSAID) to Small Peptides for Generating Multifunctional Supramolecular Nanofibers/hydrogels
Beilstein Journal of Organic Chemistry, v. 9, May 2013, p. 908-917
Li, Jiayang; Kuang, Yi; Shi, Junfeng; Gao, Yuan; Zhou, Jie; Xu, Bing Article

2012 5

“Molecular Trinity” for Soft Nanomaterials: Integrating Nucleobases, Amino Acids, and Glycosides to Construct Multifunctional Hydrogelators
Soft Matter, v. 8, (10), March 2012, p. 2801-2806
Li, Xinming; Kuang, Yi; Xu, Bing Article
Catalytic Dephosphorylation of Adenosine Monophosphate (AMP) to Form Supramolecular Nanofibers/hydrogels
Chemical Communications, v. 48, (15), February 2012, p. 2098-2100
Du, Xuewen; Li, Junfeng; Gao, Yuan; Kuang, Yi; Xu, Bing Article
Post-self-assembly Cross-linking of Molecular Nanofibers for Oscillatory Hydrogels
Langmuir, v. 28, (6), February 2012, p. 3063-3066
Zhang, Ye; Li, Ning; Delgado, Jorge; Gao, Yuan; Kuang, Yi; Fraden, Seth; Epstein, Irving R.; Xu, Bing Article
Supramolecular Hydrogel of Kanamycin Selectively Sequesters 16S rRNA
Chemical Communications, v. 48, (74), September 2012, p. 9257-9259
Yang, Zhimou; Kuang, Yi; Li, Xinming; Zhou, Ning; Zhang, Ye; Xu, Bing Article
Supramolecular Hydrogels Formed by the Conjugates of Nucleobases, Arg-Gly-Asp (RGD) Peptides, and Glucosamine
Soft Matter, v. 8, (28), July 2012, p. 7402-7404
Li, Xinming; Du, Xuewen; Gao, Yuan; Shi, Junfeng; Kuang, Yi; Xu, Bing Article

2011 5

Multifunctional, Biocompatible Supramolecular Hydrogelators Consist Only of Nucleobase, Amino Acid, and Glycoside
Journal of the American Chemical Society, v. 133, (43), November 2011, p. 17513-17518
Li, Xinming; Kuang, Yi; Shi, Junfeng; Gao, Yuan; Lin, Hsin-Chieh; Xu, Bing Article
Supramolecular Hydrogelators of N-terminated Dipeptides Selectively Inhibit Cancer Cells
Chemical Communications, v. 47, (47), December 2011, p. 12625-12627
Kuang, Yi; Gao, Yuan; Xu, Bing Article
Supramolecular Hydrogels Based on the Epitope of Potassium Ion Channels
Chemical Communications, v. 47, (31), August 2011, p. 8772-8774
Kuang, Yi; Gao, Yuan; Shi, Junfeng; Lin, Hsin-Chieh; Xu, Bing Article
Supramolecular Nanofibers and Hydrogels of Nucleopeptides
Angewandte Chemie - International Edition, v. 50, (40), September 2011, p. 9365-9369
Li, Xinming; Kuang, Yi; Lin, Hsin-Chieh; Gao, Yuan; Shi, Junfeng; Xu, Bing Article
Versatile Small-molecule Motifs for Self-assembly in Water and the Formation of Biofunctional Supramolecular Hydrogels
Langmuir, v. 27, (2), January 2011, p. 529-537
Zhang, Ye; Kuang, Yi; Gao, Yuan; Xu, Bing Article

2010 4

Aromatic-Aromatic Interactions Induce the Self-Assembly of Pentapeptidic Derivatives in Water To Form Nanofibers and Supramolecular Hydrogels
Journal of the American Chemical Society, v. 132, (8), February 2010, p. 2719-2728
Ma, Nlung; Kuang, Yi; Gao, Yuan; Zhang, Yan; Gao, Ping; Xu, Bing Article
Enzymatic Formation of a Photoresponsive Supramolecular Hydrogel
Chemical Communications, v. 46, (29), 2010, p. 5364-5366
Li, Xinming; Gao, Yuan; Kuang, Yi; Xu, Bing Article
Enzyme-instructed Self-assembly of Peptide Derivatives to Form Nanofibers and Hydrogels
Biopolymers, v. 94, (1), January 2010, p. 19-31
Gao, Yuan; Yang, Zhimou; Kuang, Yi; Ma, Man-Lung; Li, Jiayang; Zhao, Fan; Xu, Bing Article
Molecular Nanofibers of Olsalazine Form Supramolecular Hydrogels for Reductive Release of an Anti-inflammatory Agent
Journal of the American Chemical Society, v. 132, (50), December 2010, p. 17707-17709
Li, Xinming; Li, Jiayang; Gao, Yuan; Kuang, Yi; Shi, Junfeng; Xu, Bing Article

2009 2

Enzyme-Instructed Molecular Self-assembly Confers Nanofibers and a Supramolecular Hydrogel of Taxol Derivative
Journal of the American Chemical Society, v. 131, (38), September 2009, p. 13576-13577
Gao, Yuan; Kuang, Yi; Guo, Zufeng; Guo, Zhihong; Krauss, Isaac J.; Xu, Bing Article
Supramolecular Hydrogel of a D-Amino Acid Dipeptide for Controlled Drug Release in Vivo
Langmuir, v. 25, (15), August 2009, p. 8419-8422
Liang, Gaolin; Yang, Zhimou; Zhang, Rongjun; Li, Lihua; Fan, Yijun; Kuang, Yi; Gao, Yuan; Wang, Ting; Lu, W. William; Xu, Bing Article

2008 1

Multifunctional Yolk-shell Nanoparticles: A Potential MRI Contrast and Anticancer Agent
Journal of the American Chemical Society, v. 130, (35), September 2008, p. 11828-11833
Gao, Jinhao; Liang, Gaolin; Cheung, Jerry S.; Pan, Yue; Kuang, Yi; Zhao, Fan; Zhang, Bei; Zhang, Xixiang; Wu, Ed X.; Xu, Bing Article

2007 2

FePt@CoS2 Yolk-shell Nanocrystals as a Potent Agent to Kill HeLa Cells
Journal of the American Chemical Society, v. 129, (5), February 2007, p. 1428-1433
Gao, Jinhao; Liang, Gaolin; Zhang, Bei; Kuang, Yi; Zhang, Xixiang; Xu, Bing Article
Using Congo Red to Report Intracellular Hydrogelation Resulted From Self-assembly of Small Molecules
Chemical communications, (40), 2007, p. 4096-4098
Liang, Gaolin; Xu, Keming; Li, Lihua; Wang, Ling; Kuang, Yi; Yang, Zhimou; Xu, Bing Article


No Publications


No Publications


No Publications






Teaching Assignment

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2021-22 Winter 0 2021-22 Fall 3 2020-21 Summer 1 2020-21 Spring 3 2020-21 Winter 0 2020-21 Fall 2

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BIEN2610 Chemical Biology for Engineers
UROP1100E Undergraduate Research Opportunities Series 1
UROP3100E Undergraduate Research Opportunities Series 3


UROP1000 Undergraduate Research Opportunities


BIEN2410 Cellular and Systems Physiology for Engineers
CENG4920 Chemical Engineering Capstone Design
CENG4980S Investigation Project


BIEN2610 Chemical Biology for Engineers
BIEN3910 Bioengineering Laboratory


No Teaching Assignments


No Teaching Assignments






Research Postgraduate (RPG) Supervision From January 2019 to December 2022 (As of 30 January 2022)

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All Supervisions Current RPGs Graduated RPGs

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Current RPGs

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Doctor of Philosophy LIANG, Zhenghua
Bioengineering( 2021 - )

LI, Cheuk Yin
Bioengineering( 2020 - )

HU, Yaxin
Bioengineering( 2019 - )

TAN, Kaixin
Chemical and Biomolecular Engineering( 2019 - )

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Master of Philosophy YAU, Wai Laam
Chemical and Biomolecular Engineering( 2021 - )

ZENG, Jiayu
Bioscience and Biomedical Engineering( 2021 - )

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Graduated RPGs

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Master of Philosophy LIANG, Zhenghua
Chemical and Biomolecular Engineering( Completed in 2021 )

SETIASABDA, Kharis Daniel
Bioengineering( Completed in 2021 )

LI, Cheuk Yin
Bioengineering( Completed in 2020 )









ProjectsFrom January 2020 to December 2022

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All Projects 4

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No Projects.
Developing Advanced Photoriboswitch for Bidirectional Regulations of mRNAs in Mammalian Cells


研發可感應光照在細胞中雙向調控蛋白質表達的新型mRNA控制迴路 Leading


RGC - General Research Fund


Project Team (HKUST)
KUANG Becki Yi (Lead)


2022 -




Development of Effective and Selective iPSC-derived Cell Purification Platform for Drug Screening


研發一種用於藥物篩選的高效精準iPSC分化細胞純化方法 Leading


RGC - General Research Fund


Project Team (HKUST)
KUANG Becki Yi (Lead)


2021 -




Development of fast detection platform for microRNA activity in living cells


研發無損傷檢測活細胞中小分子核糖核酸活性的方法 Leading


Guangdong Natural Science Foundation


Project Team (HKUST)
KUANG Becki Yi (Lead)


2020 -




High-performance cell type selection using synthetic RNA circuit and functional molecular self-assembly


一種利用RNA控制迴路與分子自組裝的高效細胞純化方法 Leading


RGC - Early Career Scheme


Project Team (HKUST)
KUANG Becki Yi (Lead)


2020 -