Pingbo HUANG
黄平波
PhD in Physiology
University of Cincinnati, 1994

Professor
Division of Life Science
Department of Chemical and Biological Engineering



(852) 2358 7305
bohuangp@ust.hk
Room 5463
Personal Web

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ORCID
0000-0002-4560-8760

Scopus ID
7403658576




Research Interest Publications Projects Teaching Assignment RPG Supervision Space used




Research Interest

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Sensory neurobiology
Mechanotransduction of hair cells
Hearing
Ion channels
Molecular mechanobiology



Publications

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All Years 68 2022 0 2021 4 2020 5 2019 4 2018 1 2017 5 2016 49

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2021 4

Alternative Splicing of Three Genes Encoding Mechanotransduction-Complex Proteins in Auditory Hair Cells
eNeuro, v. 8, (1), January 2021, article number ENEURO.0381-20.2020, p. 1-11
Zhou, Zijing; Yu, Xiaojie; Jiang, Biaobin; Feng, Wanying; Tian, Ye; Liu, Zhiyong; Wang, Jiguang; Huang, Pingbo Article
Analyzing Protein-protein Interactions In Rare Cells Using Microbead-based Single-molecule Pulldown Assay
Lab on a Chip, v. 21, (16), 15 June 2021, p. 3137-3149
Zhao, Qirui; Shen, Yusheng; Li, Xiaofen; Tian, Fang; Yu, Xiaojie; Yobas, Levent; Park, Hyo Keun; Duan, Yuanyuan; Huang, Pingbo Article
Opposing roles of E3 ligases TRIM23 and TRIM21 in regulation of ion channel ANO1 protein levels
Journal of Biological Chemistry, v. 296, January-June 2021, article number 100738
Cao, Xu; Zhou, Zijing; Tian, Ye; Liu, Zhengzhao; Cheng, Kar On; Chen, Xibing; Hu, Wenbao; Wong, Yuk Ming; Li, Xiaofen; Zhang, Hailin; Hu, Ronggui; Huang, Pingbo Article
Unified description of compressive modulus revealing multiscale mechanics of living cells
Physical Review Research, v. 3, (4), December 2021, article number 043166
Guan, Dongshi; Shen, Yuesheng; Zhang, Rui; Huang, Pingbo; Lai, Pik-Yin; Tong, Penger Article

2020 5

CFTR Is a Negative Regulator of γδ T Cell IFN-γ Production and Antitumor Immunity
Cellular and Molecular Immunology, v. 18, (8), 2020, p. 1934-1944
Duan, Yuanyuan; Li, Guangqiang; Xu, Miaomiao; Qi, Xiaofei; Deng, Mingxia; Lin, Xuejia; Lei, Zhiwei; Hu, Yi; Jia, Zhenghu; Yang, Quanli; Cao, Guangchao; Liu, Zonghua; Wen, Qiong; Li, Zhenhua; Tang, Jie; Zhang, Wei Kevin; Huang, Pingbo; Zheng, Limin; Flavell, Richard A.; Hao, Jianlei; Yin, Zhinan Article
Deafness mutation D572N of TMC1 destabilizes TMC1 expression by disrupting LHFPL5 binding
Proceedings of the National Academy of Sciences of the United States of America, v. 117, (47), November 2020, p. 29894-29903
Yu, Xiaojie; Zhao, Qirui; Li, Xiaofen; Chen, Yixuan; Tian, Ye; Liu, Shuang; Xiong, Wei; Huang, Pingbo Article
The role of entrance functionalization in carbon nanotube-based nanofluidic systems: An intrinsic challenge
Physics of Fluids, v. 33, (1), January 2021, article number 012015
Tao, Ran; Gao, Xiang; Lin, Dewu; Chen, Yixuan; Jin, Yakang; Chen, Xibing; Yao, Shuhuai; Huang, Pingbo; Zhang, Jin; Li, Zhigang Article
A novel nanobead-based single-molecule pull-down for cell populations single cells
64th Annual Meeting of the Biophysical Society (bps 2020), San Diego, USA, 15-19 February 2020
Zhao, Qirui; Shen, Yusheng; Tian, Fang; Yobas, Levent; Park, Hyo Keun; Huang, Pingbo Conference paper
Physical and functional interactions of TMC1 and TMHS in cochlear hair cells
43rd Annual MidWinter Meeting of ARO (Association for Research in Otolaryngology),, San Jose, USA., 25-29 Jan 2020
Yu, Xiaojie; Zhao, Qirui; Li, Xiaofen; Xiong, Wei; Huang, Pingbo Conference paper

2019 4

Localization of TMC1 and LHFPL5 in Auditory Hair Cells in Neonatal and Adult Mice
The FASEB Journal, v. 33, (6), June 2019, p. 6838-6851
Li, Xiaofen; Yu, Xiaojie; Chen, Xibing; Liu, Zhengzhao; Wang, Guangqin; Li, Chao; Wong, Elaine; Sham, Maihar; Tang, Jie; Xiong, Wei; Liu, Zhiyong; Huang, Pingbo Article
Surgery-free Video-oculography in Mouse models: Enabling Quantitative and Short-interval Longitudinal Assessment of Vestibular Function
Neuroscience Letters, v. 696, March 2019, p. 212-218
Yang, Xiaojie; Zhou, Shiyue; Wu, Jiaojiao; Liao, Qun; Wang, Changquan; Liu, Minghua; Qu, Lei; Zhang, Yuan; Cheng, Cheng; Chai, Renjie; Zhang, K.; Yu, Xiaojie; Huang, Pingbo; Liu, Lian; Xiong, Wei; Chen, Shi; Chen, Fangyi Article
TMC1 is an essential component of a leak channel that modulates tonotopy and excitability of auditory hair cells in mice
eLife, v. 8, October 2019, article number e47441
Liu, Shuang; Wang, Shufeng; Zou, Linzhi; Li, Jie; Song, Chenmeng; Chen, Jiaofeng; Hu, Qun; Liu, Lian; Huang, Pingbo; Xiong, Wei Article
Two antagonizing TRIM23 and TRIM21 E3 ligases regulate ANO1 channel homeostasis.
The 7th International Ion Channel Conference (IICC-7), Hangzhou, China, 16-20 June 2019
Cao, Xu; Zhou, Zijing; Liu, Zhengzhao; Chen, Xibing; Hu, Wenbao; Li, Xiaofen; Hu, ronggui; Zhang, hailin; Huang, Pingbo Conference paper

2018 1

Mechaosensitive channels: from osmosensing to hearing
The 10th Asian Biophysics Association (ABA) Symposium in conjunction with Australian Society for Biophysics Meeting, Melbourne, Australia, 2-6 December 2018
Huang, Pingbo Conference paper

2017 5

Mechanical Characterization of Microengineered Epithelial Cysts by Using Atomic Force Microscopy
Biophysical Journal, v. 112, (2), January 2017, p. 398-409
Shen, Yusheng; Guan, Dongshi; Serien, Daniela; Takeuchi, Shoji; Tong, Penger; Yobas, Levent; Huang, Pingbo Article
The complex of TRIP-Br1 and XIAP ubiquitinates and degrades multiple adenylyl cyclase isoforms
eLife, v. 6, June 2017, article number e28021
Hu, Wenbao; Yu, Xiaojie; Liu, Zhengzhao; Sun, Ying; Chen, Xibing; Yang, Xin; Li, Xiaofen; Lam, Wai Kwan; Duan, Yuanyuan; Cao, Xu; Steller, Hermann; Liu, Kai; Huang, Pingbo Article
ANO1 is ubiquitinated and stabilized by TRIM23 E3 ligase
The 6th International Ion Channel Conference, Qingdao, China, 23-27 June 2017
Cao, Xu; Zhou, Zijing; Chen, Xibing; Hu, Wenbao; Liu, zhengzhao; Hu, ronggui; Zhang, hailin; Huang, Pingbo Conference paper
Localization and physical/functional interactions of TMC1 and TMHS in hair cells
The 3rd International Symposium on Mechanobiology (ISMB 2017) , Singapore, 11-14 December 2017
Liu, Xiaofen; Yu, Xiaojie; Chen, Xibing; Liu, Zhengzhao; Zhao, Qirui; Wong, elan; Sham, mei har; He, jufang; Huang, Pingbo Conference paper
TRIM23 ubiquitinates and stabilizes ANO1
The 6th International Ion Channel Conference, Qingdao, China, 23-27 June 2017
Xu, cao; Zhou, Zijing; Liu, zhengzhao; Chen, xibing; Hu, Wenbao; Hu, ronggui; Zhang, hailin; Huang, Pingbo Conference paper

2016 5

Actinin-1 Binds to the C-terminus of A_2B Adenosine Receptor (A_2BAR) and Enhances A_2BAR Cell-surface Expression
Biochemical Journal, v. 473, (14), 2016, p. 2179-2186
Sun, Ying; Hu, Wenbao; Yu, Xiaojie; Liu, Zhengzhao; Tarran, Robert; Ravid, Katya; Huang, Pingbo Article
Adenosine A_2B Receptor: From Cell Biology to Human Diseases
Frontiers in Chemistry, v. 4, (AUG), August 2016, article number 37
Sun, Ying; Huang, Pingbo Article
Mechanosensitivity of wild-type and G551D cystic fibrosis transmembrane conductance regulator (CFTR) controls regulatory volume decrease in simple epithelia
The FASEB Journal, v. 30, (4), April 2016, p. 1579-1589
Xie, Changyan; Cao, Xu; Cheng, Xibing; Wang, Dong; Zhang, Wei Kevin; Sun, Ying; Hu, Wenbao; Zhou, Zijing; Wang, Yan; Huang, Pingbo Article
Mechanosensitivity of wild-type and G551D cystic fibrosis transmembrane conductance regulator (CFTR) controls regulatory volume decrease in epithelia
The 60th Annual Meeting of Biophysical Society, Los Angeles, California, USA, 27 February - 2 March 2016
Huang, Pingbo; Wang, Yan; Zhou, Zijing; Hu, Wenbao; Sun, Ying; Zhang, Wei; Wang, Dong; Chen, Xibing; Cao, Xu; Xie, Changyan Conference paper
TRIM23 regulates the ubiquitination and degradation of ANO1 chloride channel
The 60th Annual Meeting of Biophysical Society, Los Angeles, California, USA, 27 February - 2 March 2016
Zhang, Hailin,; Hu, Ronggui; Hu, Wenbao; Chen, Xibing; Liu, Zhengzhao; Zhou, Zijing; Cao, Xu; Huang, Pingbo Conference paper

2015 4

Cooperative control of blood compatibility and re-endothelialization by immobilized heparin and substrate topography
Acta Biomaterialia, v. 15, March 2015, p. 150-163
Ding, Yonghui; Yang, Meng; Yang, Zhilu; Luo, Rifang; Lu, Xiong; Huang, Nan; Huang, Pingbo; Leng, Yang Article
In vitro epithelial organoid generation induced by substrate nanotopography
Scientific Reports, v.5, March 2015, article number 9293
Shen, Yusheng; Hou, Youmin; Yao, Shuhuai; Huang, Pingbo; Yobas, Levent Article
Mechanical Characterization of Microengineered Epithelial Cysts Using Atomic Force Microscopy
MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, 2015, p. 173-175
Shen, Yusheng; Guan, Dongshi; Serien, Daniela; Takeuchi, Shoji; Tong, Penger; Huang, Pingbo; Yobas, Levent Conference paper
TRIP-Br1 is a novel adaptor protein for ubiquitinating and degrading multiple adenylyl cyclase isofroms by XIAP E3 ligase
9th Asian Biophysics Association (ABA) Symposium (ABA 2015), Hangzhou, China, 9-12 May 2015
Hu, Wenbao; Liu, Zhengzhao; Sun, Ying; Lam, Wai Kwan; Duan, Yuanyuan; Huang, Pingbo Conference paper

2014 4

Directing Vascular Cell Selectivity and Hemocompatibility on Patterned Platforms Featuring Variable Topographic Geometry and Size
ACS Applied Materials and Interfaces, v. 6, (15), August 2014, p. 12062-12070
Ding, Yonghui; Yang, Zhilu; Bi, Cathy W.C.; Yang, Meng; Xu, Sherry Li; Lu, Xiong; Huang, Nan; Huang, Pingbo; Leng, Yang Article
Modulation of Protein Adsorption, Vascular Cell Selectivity and Platelet Adhesion by Mussel-inspired Surface Functionalization
Journal of Materials Chemistry B: Materials for biology and medicine, v. 2, (24), June 2014, p. 3819-3829
Ding, Yonghui; Yang, Zhilu; Bi, Wenchuan; Yang, Meng; Zhang, Jingcheng; Xu, Sherry Li; Lu, Xiong; Huang, Nan; Huang, Pingbo; Leng, Yang Article
In vitro epithelial organoid generation induced by substrate nanotopography
International Symposium on Mechanobiology (ISMB 2014), Okayama University, Japan, 20-23 May 2014
Shen, Yusheng; Huang, Pingbo; Yobas, Levent Conference paper
Wild type and G551D CFTR control epithelial regulatory volume decrease as volume-sensitive channel
The Second International Symposium on Mechanobiology (ISMB 2014), Okayama, Japan, 20-23 May 2014
Xie, Changyan; Cao, Xu; Zhang, Wei; Sun, Ying; Hu, Wenbao; Wang, Yan; Huang, Pingbo Conference paper

2013 1

Organic Electrochemical Transistor Array for Recording Transepithelial Ion Transport of Human Airway Epithelial Cells
Advanced Materials, v. 25, (45), December 2013, p. 6575-6580
Yao, Chunlei; Xie, Changyan; Lin, Peng; Yan, Feng; Huang, Pingbo; Hsing, I-Ming Article

2012 6

A novel mechanism of control of NF kappa B activation and inflammation involving A(2B) adenosine receptors
Journal of cell science, v. 125, (19), 2012, p. 4507-4517
Sun, Ying; Duan, Yuanyuan; Eisenstein, Anna S.; Hu, Wenbao; Quintana, Adrien; Lam, Wai Kwan; Wang, Yan; Wu, Zhenguo; Ravid, Katya; Huang, Pingbo Article
Impaired CFTR-dependent amplification of FSH-stimulated estrogen production in cystic fibrosis and PCOS
The Journal of clinical endocrinology and metabolism, v. 97, (3), 2012, p. 923-932
Chen, H.; Guo, J.H.; Lu, Y.C.; Ding, G.L.; Yu, M.K.; Tsang, L.L.; Fok, K.L.; Liu, X.M.; Zhang, X.H.; Chung, Y.W.; Huang, P.; Huang, H.; Chan, H.C. Article
Keratin K18 Increases Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Surface Expression by Binding to Its C-terminal Hydrophobic Patch
Journal of Biological Chemistry, v. 287, (48), 2012, Nov, p. 40547-40559
Duan, Yuanyuan; Sun, Ying; Zhang, Fan; Zhang, Wei; Wang, Dong; Wang, Yan; Cao, Xu; Hu, Wenbao; Xie, Changyan; Cuppoletti, John; Magin, Thomas Michael; Wang, Haixia; Wu, Zhenguo; Li, Ning; Huang, Pingbo Article
Microcapillary-assisted dielectrophoresis for single-particle positioning
Lab on a chip, v. 12, (20), 2012, p. 4085-4092
Luo, Yuan; Cao, Xu; Huang, Pingbo; Yobas, Levent Article
Ligand-independent control of the NFkappaB pathway and inflammation by A2B adenosine receptors
Purine 2012, Fukuoka, Japan, May 31-Jun 2 2012
Sun, Ying; Duan, Yuanyuan; Eisenstein, Ann; Hu, Wenbao; Quintana, Adrien; Lam, Wai Kwan; Wang, Yan; Wu, Zhenguo; Ravid, Kataya; Huang, Pingbo Conference paper
Physical and functional interactins of A2B adenosine receptors with alpha-actinin-1
Purine 2012, Fukuoka, Japan, May 31-Jun 2 2012
Sun, Ying; Sun, Fengqiang; Ravid, Kataya; Huang, Pingbo Conference paper

2011 2

Defective CFTR-Dependent CREB Activation Results in Impaired Spermatogenesis and Azoospermia
PLoS ONE, v. 6, (5), May 2011
Xu, Wen Ming; Chen, Jing; Chen, Hui; Diao, Rui Ying; Fok, Kin Lam; Dong, Jian Da; Sun, Ting Ting; Chen, Wen Ying; Yu, Mei Kuen; Zhang, Xiao Hu; Tsang, Lai Ling; Lau, Ann; Shi, Qi Xian; Shi, Qing Hua; Huang, Ping Bo; Chan, Hsiao Chang Article
Mechanosensitivity of CFTR in transepithelial anion secretion and volume regulation
The 7th Asian Biophysics Association Symposium, Delhi, India, , 2011
Huang, Pingbo Conference paper

2010 4

Involvement of CFTR in oviductal HCO3- secretion and its effect on soluble adenylate cyclase-dependent early embryo development
Human reproduction, v. 25, (7), 2010, JUL, p. 1744-1754
Chen, Min Hui; Chen, Hui; Zhou, Zhen; Ruan, Ye Chun; Wong, Hau Yan; Lu, Yong Chao; Guo, Jing Hui; Chung, Yiu Wa; Huang, Ping Bo; Huang, He Feng; Zhou, Wen Liang; Chan, Hsiao Chang Article
Mechanosensitive Gating of CFTR
Nature Cell Biology, v. 12, (5), 2010, May, p. 507-512
Zhang, Wei Kevin; Wang, Dong; Duan, Yuanyuan; Loy, Michael M.T.; Chan, Hsiao Chang; Huang, Pingbo Article
Pathologically Activated Neuroprotection via Uncompetitive Blockade of N-Methyl-D-aspartate Receptors with Fast Off-rate by Novel Multifunctional Dimer Bis(propyl)-cognitin
Journal of biological chemistry, v. 285, (26), 2010, JUN 25, p. 19947-19958
Luo, Jialie; Li, Wenming; Zhao, Yuming; Fu, Hongjun; Ma, Dik-Lung; Tang, Jing; Li, Chaoying; Peoples, Robert W.; Li, Fushun; Wang, Qinwen; Huang, Pingbo; Xia, Jun; Pang, Yuanping; Han, Yifan Article
Keratin 18 increases CFTR surface expression by binding to its C-terminal hydrophobic patch
Joint Scientific Meeting of Hong Kong Society of Neurosceinces and The Biophysical Society of Hong Kong, HKU, Hong Kong, June 7-8, 2010
Duan, Yuanyuan; Zhang, Fan; Zhang, Wei; Wang, Dong; Wang, Yan; Sun, Ying; Yang, Pingfang; Cuppoletti, John; Magin, Thomas; Wang, Haixia; Wu, Zhenguo; Ning, Li; Huang, Pingbo Conference paper

2008 7

Adenosine promotes IL-6 release in airway epithelia
JOURNAL OF IMMUNOLOGY, v. 180, (6), 2008, MAR 15, p. 4173-4181
Sun, Ying; Wu, Fan; Sun, Fengqiang; Huang, Pingbo Article
Apical adenosine regulates basolateral Ca2+-activated potassium channels in human airway Calu-3 epithelial cells
American journal OF physiology-cell Physiology, v. 294, (6), 2008, JUN, p. C1443-C1453
Wang, Dong; Sun, Ying; Zhang, Wei; Huang, Pingbo Article
EGY1 plays a role in regulation of endodermal plastid size and number that are involved in ethylene-dependent gravitropism of light-grown Arabidopsis hypocotyls
Plant molecular biology, v. 66, (4), 2008, MAR, p. 345-360
Guo, Di; Gao, Xiaorong; Li, Hao; Zhang, Tao; Chen, Gu; Huang, Pingbo; An, Lijia; Li, Ning Article
Functional coupling of Gs and CFTR is independent of their association with lipid rafts in epithelial cells
Pflügers Archiv - European Journal of Physiology, v. 456, (5), 2008, AUG, p. 929-938
Wang, Dong; Wang, Wen; Duan, Yuanyuan; Sun, Ying; Wang, Yan; Huang, Pingbo Article
Intracellular spatial control of fluorescent magnetic nanoparticles
Journal of the American Chemical Society, v. 130, (12), 2008, MAR 26, p. 3710+
Gao, Jinhao; Zhang, Wei; Huang, Pingbo; Zhang, Bei; Zhang, Xixiang; Xu, Bing Article
A2B Adenosine Receptor Negatively Regulates NFB Activation through Physical Interaction with p105
48th Annual Meeting of the American Society for Cell Biology, The Moscone Center, San Francisco, California (USA), 13-17 Dec 2008
Sun, Y.; Lam, W.; Duan, Y.; Quintana, A.; Sun, F.; Wu, Z.; Huang, P. Conference paper
The C-Terminal Hydrophobic Patch of CFTR Interacts with Cytoskeletal Keratin 18 for Stable Surface Expression
48th Annual Meeting of the American Society for Cell Biology, The Moscone Center, San Francisco, California (USA), 13-17 Dec 2008
Duan, Y.; Zhang, F.; Wang, D.; Zhang, W.; Sun, Y.; Yang, P.; Cuppoletti, J.; Wang, H.; Wu, Z.; Magin, T.; Huang, P. Conference paper

2007 1

Novel dimeric bis(7)-tacrine proton-dependently inhibits NMDA-activated currents
Biochemical and biophysical research communications, v. 361, (2), 2007, SEP 21, p. 505-509
Luo, Jialie; Li, Wenming; Liu, Yuwei; Zhang, Wei; Fu, Hongjun; Lee, Nelson T.K.; Yu, Hua; Pang, Yuanping; Huang, Pingbo; Xia, Jun; Li, Zhi-Wang; Li, Chaoying; Han, Yifan Article

2006 2

Micromolding of PDMS scaffolds and microwells for tissue culture and cell patterning: A new method of microfabrication by the self-assembled micropatterns of diblock copolymer micelles
Polymer, v. 47, (14), 2006, JUN 28, p. 5124-5130
Mi, Yongli; Chan, Yannie; Trau, Dieter; Huang, Pingbo; Chen, Erqiang Article
Cytoskeletal Keratin 18 Regulates the Cell Surface Expression of CFTR Channel via Direct Binding
4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS 2006), Cheung Kung Hai Conference Centre, Hong Kong City (Hong Kong-S.A.R of China), 30 Nov-2 Dec 2006
Duan, Yuanyuan; Yang, Pingfan; Zhang, Wei; Sun, Ying; Wang, Dong; Huang, Pingbo Conference paper

2005 2

Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium
Journal of Biological Chemistry, v. 280, (9), 2005, p. 7997-8003
Barnes, A.P.; Livera, G.; Huang, P.; Sun, C.; O'Neal, W.K.; Conti, M.; Stutts, M.J.; Milgram, S.L. Article
Regulation of CFTR channels by HCO₃^?-sensitive soluble adenylyl cyclase in human airway epithelial cells
American journal OF physiology-cell Physiology, v. 289, (5), 2005, NOV, p. C1145-C1151
Wang, Yan; Lam, Chak Sum; Wu, Fan; Wang, Wen; Duan, Yuanyuan; Huang, Pingbo Article

2004 3

Local regulation of cystic fibrosis transmembrane regulator and epithelial sodium channel in airway epithelium.
Proc Am Thorac Soc, v. 1, (1), 2004, p. 33-37
Huang, P.; Gilmore, E.; Kultgen, P.; Barnes, P.; Milgram, S.; Stutts, M.J. Article
Voltage-dependent anion channel-1 (VDAC-1) contributes to ATP release and cell volume regulation in murine cells
Journal of General Physiology, v. 124, (5), 2004, p. 513-526
Okada, S.F.; O'Neal, W.K.; Huang, P.; Nicholas, R.A.; Ostrowski, L.E.; Craigen, W.J.; Lazarowski, E.R.; Boucher, R.C. Article
Contribution of Vdac (Voltage-Dependent Anion Channel) to Epithelial ATP Release And Cell Volume Regulation
Purines 2004, Chapel Hill, North Carolina, USA
Okada, Seiko F.; O'neal, Wanda K.; Huang, Pingbo; Nicholas, Robert A.; Craigen, William J.; Ostrowski, Lawrence E.; Lazarowski, Eduardo R.; Boucher, Richard C. Conference paper

2001 1

Compartmentalized autocrine signaling to cystic fibrosis transmembrane conductance regulator at the apical membrane of airway epithelial cells
Proceedings of the National Academy of Sciences of the United States of America, 98(24), 14120-14125
Huang, P.; Lazarowski, E.R.; Tarran, R.; Milgram, S.L.; Boucher, R.C.; Stutts, M.J. Article

2000 1

PKA holoenzyme is functionally coupled to CFTR by AKAPs
Am. J. Physiol, 278, C417-C422
Huang, P.; Trotter, K.; Boucher, R.C.; Milgram, S.L.; Stutts, M.J. Article

1998 1

Lysophosphatidylglycerol: a novel effective detergent for solubilizing and purifying the cystic fibrosis transmembrane conductance regulator
Anal Biochem, v. 259, 1998, p. 89-97
Huang, Pingbo; Liu, Q.; Scarborough, GA Article

1996 1

Functional expression of the cystic fibrosis transmembrane conductance regulator in yeast
Biochim Biophys Acta (Biomembranes), v. 1281, 1996, p. 80-90
Huang, Pingbo; Stroffekova, K.; Cuppoletti, J.; Mahanty, SK; Scarborough, GA Article

1993 1

Stimulus-associated protein in gastric parietal cell detected using antimelittin antibody
Am. J. Physiol, v. 264, 1993, p. G637-G644
Cuppoletti, J.; Huang, Pingbo; Kaetzel, M.A.; Malinowska, D.H. Article

1992 3

Structure-function relationships in the interaction of amphipathic helical polypeptides with the gastric H/K ATPase
Annals of the New York Academy of Sciences, v. 671, p. 443-445, 1992
Cuppoletti, J.; Chernyak, B.V.; Huang, Pingbo; Malinowska, D.H. Article
The role of afferent C fibers in electroacupuncture of "Zusanli" point activating nucleus raphe magnus
Chinese J. Physiol. Sci, v. 8, (3), 1992, p. 257-267
Liu, X.; Jiang, M.; Huang, Pingbo; Zou, T. Article
Bioactive peptide inhibitors and an endogenous pariteal cell protein interactions with the gastric H/K ATPase
NATO Advanced Research Conference Held in York, England, 1992
Cuppoletti, J.; Huang, Pingbo; Malinowska, D.H. Conference paper


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Article 4

Alternative Splicing of Three Genes Encoding Mechanotransduction-Complex Proteins in Auditory Hair Cells
eNeuro, v. 8, (1), January 2021, article number ENEURO.0381-20.2020, p. 1-11
Zhou, Zijing; Yu, Xiaojie; Jiang, Biaobin; Feng, Wanying; Tian, Ye; Liu, Zhiyong; Wang, Jiguang; Huang, Pingbo
Analyzing Protein-protein Interactions In Rare Cells Using Microbead-based Single-molecule Pulldown Assay
Lab on a Chip, v. 21, (16), 15 June 2021, p. 3137-3149
Zhao, Qirui; Shen, Yusheng; Li, Xiaofen; Tian, Fang; Yu, Xiaojie; Yobas, Levent; Park, Hyo Keun; Duan, Yuanyuan; Huang, Pingbo
Opposing roles of E3 ligases TRIM23 and TRIM21 in regulation of ion channel ANO1 protein levels
Journal of Biological Chemistry, v. 296, January-June 2021, article number 100738
Cao, Xu; Zhou, Zijing; Tian, Ye; Liu, Zhengzhao; Cheng, Kar On; Chen, Xibing; Hu, Wenbao; Wong, Yuk Ming; Li, Xiaofen; Zhang, Hailin; Hu, Ronggui; Huang, Pingbo
Unified description of compressive modulus revealing multiscale mechanics of living cells
Physical Review Research, v. 3, (4), December 2021, article number 043166
Guan, Dongshi; Shen, Yuesheng; Zhang, Rui; Huang, Pingbo; Lai, Pik-Yin; Tong, Penger


Expand All Collapse All


Article 3

CFTR Is a Negative Regulator of γδ T Cell IFN-γ Production and Antitumor Immunity
Cellular and Molecular Immunology, v. 18, (8), 2020, p. 1934-1944
Duan, Yuanyuan; Li, Guangqiang; Xu, Miaomiao; Qi, Xiaofei; Deng, Mingxia; Lin, Xuejia; Lei, Zhiwei; Hu, Yi; Jia, Zhenghu; Yang, Quanli; Cao, Guangchao; Liu, Zonghua; Wen, Qiong; Li, Zhenhua; Tang, Jie; Zhang, Wei Kevin; Huang, Pingbo; Zheng, Limin; Flavell, Richard A.; Hao, Jianlei; Yin, Zhinan
Deafness mutation D572N of TMC1 destabilizes TMC1 expression by disrupting LHFPL5 binding
Proceedings of the National Academy of Sciences of the United States of America, v. 117, (47), November 2020, p. 29894-29903
Yu, Xiaojie; Zhao, Qirui; Li, Xiaofen; Chen, Yixuan; Tian, Ye; Liu, Shuang; Xiong, Wei; Huang, Pingbo
The role of entrance functionalization in carbon nanotube-based nanofluidic systems: An intrinsic challenge
Physics of Fluids, v. 33, (1), January 2021, article number 012015
Tao, Ran; Gao, Xiang; Lin, Dewu; Chen, Yixuan; Jin, Yakang; Chen, Xibing; Yao, Shuhuai; Huang, Pingbo; Zhang, Jin; Li, Zhigang

Conference paper 2

A novel nanobead-based single-molecule pull-down for cell populations single cells
64th Annual Meeting of the Biophysical Society (bps 2020), San Diego, USA, 15-19 February 2020
Zhao, Qirui; Shen, Yusheng; Tian, Fang; Yobas, Levent; Park, Hyo Keun; Huang, Pingbo
Physical and functional interactions of TMC1 and TMHS in cochlear hair cells
43rd Annual MidWinter Meeting of ARO (Association for Research in Otolaryngology),, San Jose, USA., 25-29 Jan 2020
Yu, Xiaojie; Zhao, Qirui; Li, Xiaofen; Xiong, Wei; Huang, Pingbo


Expand All Collapse All


Article 3

Localization of TMC1 and LHFPL5 in Auditory Hair Cells in Neonatal and Adult Mice
The FASEB Journal, v. 33, (6), June 2019, p. 6838-6851
Li, Xiaofen; Yu, Xiaojie; Chen, Xibing; Liu, Zhengzhao; Wang, Guangqin; Li, Chao; Wong, Elaine; Sham, Maihar; Tang, Jie; Xiong, Wei; Liu, Zhiyong; Huang, Pingbo
Surgery-free Video-oculography in Mouse models: Enabling Quantitative and Short-interval Longitudinal Assessment of Vestibular Function
Neuroscience Letters, v. 696, March 2019, p. 212-218
Yang, Xiaojie; Zhou, Shiyue; Wu, Jiaojiao; Liao, Qun; Wang, Changquan; Liu, Minghua; Qu, Lei; Zhang, Yuan; Cheng, Cheng; Chai, Renjie; Zhang, K.; Yu, Xiaojie; Huang, Pingbo; Liu, Lian; Xiong, Wei; Chen, Shi; Chen, Fangyi
TMC1 is an essential component of a leak channel that modulates tonotopy and excitability of auditory hair cells in mice
eLife, v. 8, October 2019, article number e47441
Liu, Shuang; Wang, Shufeng; Zou, Linzhi; Li, Jie; Song, Chenmeng; Chen, Jiaofeng; Hu, Qun; Liu, Lian; Huang, Pingbo; Xiong, Wei

Conference paper 1

Two antagonizing TRIM23 and TRIM21 E3 ligases regulate ANO1 channel homeostasis.
The 7th International Ion Channel Conference (IICC-7), Hangzhou, China, 16-20 June 2019
Cao, Xu; Zhou, Zijing; Liu, Zhengzhao; Chen, Xibing; Hu, Wenbao; Li, Xiaofen; Hu, ronggui; Zhang, hailin; Huang, Pingbo


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Conference paper 1

Mechaosensitive channels: from osmosensing to hearing
The 10th Asian Biophysics Association (ABA) Symposium in conjunction with Australian Society for Biophysics Meeting, Melbourne, Australia, 2-6 December 2018
Huang, Pingbo


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Article 2

Mechanical Characterization of Microengineered Epithelial Cysts by Using Atomic Force Microscopy
Biophysical Journal, v. 112, (2), January 2017, p. 398-409
Shen, Yusheng; Guan, Dongshi; Serien, Daniela; Takeuchi, Shoji; Tong, Penger; Yobas, Levent; Huang, Pingbo
The complex of TRIP-Br1 and XIAP ubiquitinates and degrades multiple adenylyl cyclase isoforms
eLife, v. 6, June 2017, article number e28021
Hu, Wenbao; Yu, Xiaojie; Liu, Zhengzhao; Sun, Ying; Chen, Xibing; Yang, Xin; Li, Xiaofen; Lam, Wai Kwan; Duan, Yuanyuan; Cao, Xu; Steller, Hermann; Liu, Kai; Huang, Pingbo

Conference paper 3

ANO1 is ubiquitinated and stabilized by TRIM23 E3 ligase
The 6th International Ion Channel Conference, Qingdao, China, 23-27 June 2017
Cao, Xu; Zhou, Zijing; Chen, Xibing; Hu, Wenbao; Liu, zhengzhao; Hu, ronggui; Zhang, hailin; Huang, Pingbo
Localization and physical/functional interactions of TMC1 and TMHS in hair cells
The 3rd International Symposium on Mechanobiology (ISMB 2017) , Singapore, 11-14 December 2017
Liu, Xiaofen; Yu, Xiaojie; Chen, Xibing; Liu, Zhengzhao; Zhao, Qirui; Wong, elan; Sham, mei har; He, jufang; Huang, Pingbo
TRIM23 ubiquitinates and stabilizes ANO1
The 6th International Ion Channel Conference, Qingdao, China, 23-27 June 2017
Xu, cao; Zhou, Zijing; Liu, zhengzhao; Chen, xibing; Hu, Wenbao; Hu, ronggui; Zhang, hailin; Huang, Pingbo


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Article 3

Actinin-1 Binds to the C-terminus of A_2B Adenosine Receptor (A_2BAR) and Enhances A_2BAR Cell-surface Expression
Biochemical Journal, v. 473, (14), 2016, p. 2179-2186
Sun, Ying; Hu, Wenbao; Yu, Xiaojie; Liu, Zhengzhao; Tarran, Robert; Ravid, Katya; Huang, Pingbo
Adenosine A_2B Receptor: From Cell Biology to Human Diseases
Frontiers in Chemistry, v. 4, (AUG), August 2016, article number 37
Sun, Ying; Huang, Pingbo
Mechanosensitivity of wild-type and G551D cystic fibrosis transmembrane conductance regulator (CFTR) controls regulatory volume decrease in simple epithelia
The FASEB Journal, v. 30, (4), April 2016, p. 1579-1589
Xie, Changyan; Cao, Xu; Cheng, Xibing; Wang, Dong; Zhang, Wei Kevin; Sun, Ying; Hu, Wenbao; Zhou, Zijing; Wang, Yan; Huang, Pingbo

Conference paper 2

Mechanosensitivity of wild-type and G551D cystic fibrosis transmembrane conductance regulator (CFTR) controls regulatory volume decrease in epithelia
The 60th Annual Meeting of Biophysical Society, Los Angeles, California, USA, 27 February - 2 March 2016
Huang, Pingbo; Wang, Yan; Zhou, Zijing; Hu, Wenbao; Sun, Ying; Zhang, Wei; Wang, Dong; Chen, Xibing; Cao, Xu; Xie, Changyan
TRIM23 regulates the ubiquitination and degradation of ANO1 chloride channel
The 60th Annual Meeting of Biophysical Society, Los Angeles, California, USA, 27 February - 2 March 2016
Zhang, Hailin,; Hu, Ronggui; Hu, Wenbao; Chen, Xibing; Liu, Zhengzhao; Zhou, Zijing; Cao, Xu; Huang, Pingbo


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Article 2

Cooperative control of blood compatibility and re-endothelialization by immobilized heparin and substrate topography
Acta Biomaterialia, v. 15, March 2015, p. 150-163
Ding, Yonghui; Yang, Meng; Yang, Zhilu; Luo, Rifang; Lu, Xiong; Huang, Nan; Huang, Pingbo; Leng, Yang
In vitro epithelial organoid generation induced by substrate nanotopography
Scientific Reports, v.5, March 2015, article number 9293
Shen, Yusheng; Hou, Youmin; Yao, Shuhuai; Huang, Pingbo; Yobas, Levent

Conference paper 2

Mechanical Characterization of Microengineered Epithelial Cysts Using Atomic Force Microscopy
MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, 2015, p. 173-175
Shen, Yusheng; Guan, Dongshi; Serien, Daniela; Takeuchi, Shoji; Tong, Penger; Huang, Pingbo; Yobas, Levent
TRIP-Br1 is a novel adaptor protein for ubiquitinating and degrading multiple adenylyl cyclase isofroms by XIAP E3 ligase
9th Asian Biophysics Association (ABA) Symposium (ABA 2015), Hangzhou, China, 9-12 May 2015
Hu, Wenbao; Liu, Zhengzhao; Sun, Ying; Lam, Wai Kwan; Duan, Yuanyuan; Huang, Pingbo


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Article 2

Directing Vascular Cell Selectivity and Hemocompatibility on Patterned Platforms Featuring Variable Topographic Geometry and Size
ACS Applied Materials and Interfaces, v. 6, (15), August 2014, p. 12062-12070
Ding, Yonghui; Yang, Zhilu; Bi, Cathy W.C.; Yang, Meng; Xu, Sherry Li; Lu, Xiong; Huang, Nan; Huang, Pingbo; Leng, Yang
Modulation of Protein Adsorption, Vascular Cell Selectivity and Platelet Adhesion by Mussel-inspired Surface Functionalization
Journal of Materials Chemistry B: Materials for biology and medicine, v. 2, (24), June 2014, p. 3819-3829
Ding, Yonghui; Yang, Zhilu; Bi, Wenchuan; Yang, Meng; Zhang, Jingcheng; Xu, Sherry Li; Lu, Xiong; Huang, Nan; Huang, Pingbo; Leng, Yang

Conference paper 2

In vitro epithelial organoid generation induced by substrate nanotopography
International Symposium on Mechanobiology (ISMB 2014), Okayama University, Japan, 20-23 May 2014
Shen, Yusheng; Huang, Pingbo; Yobas, Levent
Wild type and G551D CFTR control epithelial regulatory volume decrease as volume-sensitive channel
The Second International Symposium on Mechanobiology (ISMB 2014), Okayama, Japan, 20-23 May 2014
Xie, Changyan; Cao, Xu; Zhang, Wei; Sun, Ying; Hu, Wenbao; Wang, Yan; Huang, Pingbo


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Article 1

Organic Electrochemical Transistor Array for Recording Transepithelial Ion Transport of Human Airway Epithelial Cells
Advanced Materials, v. 25, (45), December 2013, p. 6575-6580
Yao, Chunlei; Xie, Changyan; Lin, Peng; Yan, Feng; Huang, Pingbo; Hsing, I-Ming


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Article 4

A novel mechanism of control of NF kappa B activation and inflammation involving A(2B) adenosine receptors
Journal of cell science, v. 125, (19), 2012, p. 4507-4517
Sun, Ying; Duan, Yuanyuan; Eisenstein, Anna S.; Hu, Wenbao; Quintana, Adrien; Lam, Wai Kwan; Wang, Yan; Wu, Zhenguo; Ravid, Katya; Huang, Pingbo
Impaired CFTR-dependent amplification of FSH-stimulated estrogen production in cystic fibrosis and PCOS
The Journal of clinical endocrinology and metabolism, v. 97, (3), 2012, p. 923-932
Chen, H.; Guo, J.H.; Lu, Y.C.; Ding, G.L.; Yu, M.K.; Tsang, L.L.; Fok, K.L.; Liu, X.M.; Zhang, X.H.; Chung, Y.W.; Huang, P.; Huang, H.; Chan, H.C.
Keratin K18 Increases Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Surface Expression by Binding to Its C-terminal Hydrophobic Patch
Journal of Biological Chemistry, v. 287, (48), 2012, Nov, p. 40547-40559
Duan, Yuanyuan; Sun, Ying; Zhang, Fan; Zhang, Wei; Wang, Dong; Wang, Yan; Cao, Xu; Hu, Wenbao; Xie, Changyan; Cuppoletti, John; Magin, Thomas Michael; Wang, Haixia; Wu, Zhenguo; Li, Ning; Huang, Pingbo
Microcapillary-assisted dielectrophoresis for single-particle positioning
Lab on a chip, v. 12, (20), 2012, p. 4085-4092
Luo, Yuan; Cao, Xu; Huang, Pingbo; Yobas, Levent

Conference paper 2

Ligand-independent control of the NFkappaB pathway and inflammation by A2B adenosine receptors
Purine 2012, Fukuoka, Japan, May 31-Jun 2 2012
Sun, Ying; Duan, Yuanyuan; Eisenstein, Ann; Hu, Wenbao; Quintana, Adrien; Lam, Wai Kwan; Wang, Yan; Wu, Zhenguo; Ravid, Kataya; Huang, Pingbo
Physical and functional interactins of A2B adenosine receptors with alpha-actinin-1
Purine 2012, Fukuoka, Japan, May 31-Jun 2 2012
Sun, Ying; Sun, Fengqiang; Ravid, Kataya; Huang, Pingbo


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Article 1

Defective CFTR-Dependent CREB Activation Results in Impaired Spermatogenesis and Azoospermia
PLoS ONE, v. 6, (5), May 2011
Xu, Wen Ming; Chen, Jing; Chen, Hui; Diao, Rui Ying; Fok, Kin Lam; Dong, Jian Da; Sun, Ting Ting; Chen, Wen Ying; Yu, Mei Kuen; Zhang, Xiao Hu; Tsang, Lai Ling; Lau, Ann; Shi, Qi Xian; Shi, Qing Hua; Huang, Ping Bo; Chan, Hsiao Chang

Conference paper 1

Mechanosensitivity of CFTR in transepithelial anion secretion and volume regulation
The 7th Asian Biophysics Association Symposium, Delhi, India, , 2011
Huang, Pingbo


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Article 3

Involvement of CFTR in oviductal HCO3- secretion and its effect on soluble adenylate cyclase-dependent early embryo development
Human reproduction, v. 25, (7), 2010, JUL, p. 1744-1754
Chen, Min Hui; Chen, Hui; Zhou, Zhen; Ruan, Ye Chun; Wong, Hau Yan; Lu, Yong Chao; Guo, Jing Hui; Chung, Yiu Wa; Huang, Ping Bo; Huang, He Feng; Zhou, Wen Liang; Chan, Hsiao Chang
Mechanosensitive Gating of CFTR
Nature Cell Biology, v. 12, (5), 2010, May, p. 507-512
Zhang, Wei Kevin; Wang, Dong; Duan, Yuanyuan; Loy, Michael M.T.; Chan, Hsiao Chang; Huang, Pingbo
Pathologically Activated Neuroprotection via Uncompetitive Blockade of N-Methyl-D-aspartate Receptors with Fast Off-rate by Novel Multifunctional Dimer Bis(propyl)-cognitin
Journal of biological chemistry, v. 285, (26), 2010, JUN 25, p. 19947-19958
Luo, Jialie; Li, Wenming; Zhao, Yuming; Fu, Hongjun; Ma, Dik-Lung; Tang, Jing; Li, Chaoying; Peoples, Robert W.; Li, Fushun; Wang, Qinwen; Huang, Pingbo; Xia, Jun; Pang, Yuanping; Han, Yifan

Conference paper 1

Keratin 18 increases CFTR surface expression by binding to its C-terminal hydrophobic patch
Joint Scientific Meeting of Hong Kong Society of Neurosceinces and The Biophysical Society of Hong Kong, HKU, Hong Kong, June 7-8, 2010
Duan, Yuanyuan; Zhang, Fan; Zhang, Wei; Wang, Dong; Wang, Yan; Sun, Ying; Yang, Pingfang; Cuppoletti, John; Magin, Thomas; Wang, Haixia; Wu, Zhenguo; Ning, Li; Huang, Pingbo


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Article 5

Adenosine promotes IL-6 release in airway epithelia
JOURNAL OF IMMUNOLOGY, v. 180, (6), 2008, MAR 15, p. 4173-4181
Sun, Ying; Wu, Fan; Sun, Fengqiang; Huang, Pingbo
Apical adenosine regulates basolateral Ca2+-activated potassium channels in human airway Calu-3 epithelial cells
American journal OF physiology-cell Physiology, v. 294, (6), 2008, JUN, p. C1443-C1453
Wang, Dong; Sun, Ying; Zhang, Wei; Huang, Pingbo
EGY1 plays a role in regulation of endodermal plastid size and number that are involved in ethylene-dependent gravitropism of light-grown Arabidopsis hypocotyls
Plant molecular biology, v. 66, (4), 2008, MAR, p. 345-360
Guo, Di; Gao, Xiaorong; Li, Hao; Zhang, Tao; Chen, Gu; Huang, Pingbo; An, Lijia; Li, Ning
Functional coupling of Gs and CFTR is independent of their association with lipid rafts in epithelial cells
Pflügers Archiv - European Journal of Physiology, v. 456, (5), 2008, AUG, p. 929-938
Wang, Dong; Wang, Wen; Duan, Yuanyuan; Sun, Ying; Wang, Yan; Huang, Pingbo
Intracellular spatial control of fluorescent magnetic nanoparticles
Journal of the American Chemical Society, v. 130, (12), 2008, MAR 26, p. 3710+
Gao, Jinhao; Zhang, Wei; Huang, Pingbo; Zhang, Bei; Zhang, Xixiang; Xu, Bing

Conference paper 2

A2B Adenosine Receptor Negatively Regulates NFB Activation through Physical Interaction with p105
48th Annual Meeting of the American Society for Cell Biology, The Moscone Center, San Francisco, California (USA), 13-17 Dec 2008
Sun, Y.; Lam, W.; Duan, Y.; Quintana, A.; Sun, F.; Wu, Z.; Huang, P.
The C-Terminal Hydrophobic Patch of CFTR Interacts with Cytoskeletal Keratin 18 for Stable Surface Expression
48th Annual Meeting of the American Society for Cell Biology, The Moscone Center, San Francisco, California (USA), 13-17 Dec 2008
Duan, Y.; Zhang, F.; Wang, D.; Zhang, W.; Sun, Y.; Yang, P.; Cuppoletti, J.; Wang, H.; Wu, Z.; Magin, T.; Huang, P.


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Article 1

Novel dimeric bis(7)-tacrine proton-dependently inhibits NMDA-activated currents
Biochemical and biophysical research communications, v. 361, (2), 2007, SEP 21, p. 505-509
Luo, Jialie; Li, Wenming; Liu, Yuwei; Zhang, Wei; Fu, Hongjun; Lee, Nelson T.K.; Yu, Hua; Pang, Yuanping; Huang, Pingbo; Xia, Jun; Li, Zhi-Wang; Li, Chaoying; Han, Yifan


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Article 1

Micromolding of PDMS scaffolds and microwells for tissue culture and cell patterning: A new method of microfabrication by the self-assembled micropatterns of diblock copolymer micelles
Polymer, v. 47, (14), 2006, JUN 28, p. 5124-5130
Mi, Yongli; Chan, Yannie; Trau, Dieter; Huang, Pingbo; Chen, Erqiang

Conference paper 1

Cytoskeletal Keratin 18 Regulates the Cell Surface Expression of CFTR Channel via Direct Binding
4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS 2006), Cheung Kung Hai Conference Centre, Hong Kong City (Hong Kong-S.A.R of China), 30 Nov-2 Dec 2006
Duan, Yuanyuan; Yang, Pingfan; Zhang, Wei; Sun, Ying; Wang, Dong; Huang, Pingbo


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Article 2

Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium
Journal of Biological Chemistry, v. 280, (9), 2005, p. 7997-8003
Barnes, A.P.; Livera, G.; Huang, P.; Sun, C.; O'Neal, W.K.; Conti, M.; Stutts, M.J.; Milgram, S.L.
Regulation of CFTR channels by HCO₃^?-sensitive soluble adenylyl cyclase in human airway epithelial cells
American journal OF physiology-cell Physiology, v. 289, (5), 2005, NOV, p. C1145-C1151
Wang, Yan; Lam, Chak Sum; Wu, Fan; Wang, Wen; Duan, Yuanyuan; Huang, Pingbo


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Article 2

Local regulation of cystic fibrosis transmembrane regulator and epithelial sodium channel in airway epithelium.
Proc Am Thorac Soc, v. 1, (1), 2004, p. 33-37
Huang, P.; Gilmore, E.; Kultgen, P.; Barnes, P.; Milgram, S.; Stutts, M.J.
Voltage-dependent anion channel-1 (VDAC-1) contributes to ATP release and cell volume regulation in murine cells
Journal of General Physiology, v. 124, (5), 2004, p. 513-526
Okada, S.F.; O'Neal, W.K.; Huang, P.; Nicholas, R.A.; Ostrowski, L.E.; Craigen, W.J.; Lazarowski, E.R.; Boucher, R.C.

Conference paper 1

Contribution of Vdac (Voltage-Dependent Anion Channel) to Epithelial ATP Release And Cell Volume Regulation
Purines 2004, Chapel Hill, North Carolina, USA
Okada, Seiko F.; O'neal, Wanda K.; Huang, Pingbo; Nicholas, Robert A.; Craigen, William J.; Ostrowski, Lawrence E.; Lazarowski, Eduardo R.; Boucher, Richard C.


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Article 1

Compartmentalized autocrine signaling to cystic fibrosis transmembrane conductance regulator at the apical membrane of airway epithelial cells
Proceedings of the National Academy of Sciences of the United States of America, 98(24), 14120-14125
Huang, P.; Lazarowski, E.R.; Tarran, R.; Milgram, S.L.; Boucher, R.C.; Stutts, M.J.


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Article 1

PKA holoenzyme is functionally coupled to CFTR by AKAPs
Am. J. Physiol, 278, C417-C422
Huang, P.; Trotter, K.; Boucher, R.C.; Milgram, S.L.; Stutts, M.J.


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Article 1

Lysophosphatidylglycerol: a novel effective detergent for solubilizing and purifying the cystic fibrosis transmembrane conductance regulator
Anal Biochem, v. 259, 1998, p. 89-97
Huang, Pingbo; Liu, Q.; Scarborough, GA


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Article 1

Functional expression of the cystic fibrosis transmembrane conductance regulator in yeast
Biochim Biophys Acta (Biomembranes), v. 1281, 1996, p. 80-90
Huang, Pingbo; Stroffekova, K.; Cuppoletti, J.; Mahanty, SK; Scarborough, GA


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Article 1

Stimulus-associated protein in gastric parietal cell detected using antimelittin antibody
Am. J. Physiol, v. 264, 1993, p. G637-G644
Cuppoletti, J.; Huang, Pingbo; Kaetzel, M.A.; Malinowska, D.H.


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Article 2

Structure-function relationships in the interaction of amphipathic helical polypeptides with the gastric H/K ATPase
Annals of the New York Academy of Sciences, v. 671, p. 443-445, 1992
Cuppoletti, J.; Chernyak, B.V.; Huang, Pingbo; Malinowska, D.H.
The role of afferent C fibers in electroacupuncture of "Zusanli" point activating nucleus raphe magnus
Chinese J. Physiol. Sci, v. 8, (3), 1992, p. 257-267
Liu, X.; Jiang, M.; Huang, Pingbo; Zou, T.

Conference paper 1

Bioactive peptide inhibitors and an endogenous pariteal cell protein interactions with the gastric H/K ATPase
NATO Advanced Research Conference Held in York, England, 1992
Cuppoletti, J.; Huang, Pingbo; Malinowska, D.H.


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2016 5

Actinin-1 Binds to the C-terminus of A_2B Adenosine Receptor (A_2BAR) and Enhances A_2BAR Cell-surface Expression
Biochemical Journal, v. 473, (14), 2016, p. 2179-2186
Sun, Ying; Hu, Wenbao; Yu, Xiaojie; Liu, Zhengzhao; Tarran, Robert; Ravid, Katya; Huang, Pingbo Article
Adenosine A_2B Receptor: From Cell Biology to Human Diseases
Frontiers in Chemistry, v. 4, (AUG), August 2016, article number 37
Sun, Ying; Huang, Pingbo Article
Mechanosensitivity of wild-type and G551D cystic fibrosis transmembrane conductance regulator (CFTR) controls regulatory volume decrease in simple epithelia
The FASEB Journal, v. 30, (4), April 2016, p. 1579-1589
Xie, Changyan; Cao, Xu; Cheng, Xibing; Wang, Dong; Zhang, Wei Kevin; Sun, Ying; Hu, Wenbao; Zhou, Zijing; Wang, Yan; Huang, Pingbo Article
Mechanosensitivity of wild-type and G551D cystic fibrosis transmembrane conductance regulator (CFTR) controls regulatory volume decrease in epithelia
The 60th Annual Meeting of Biophysical Society, Los Angeles, California, USA, 27 February - 2 March 2016
Huang, Pingbo; Wang, Yan; Zhou, Zijing; Hu, Wenbao; Sun, Ying; Zhang, Wei; Wang, Dong; Chen, Xibing; Cao, Xu; Xie, Changyan Conference paper
TRIM23 regulates the ubiquitination and degradation of ANO1 chloride channel
The 60th Annual Meeting of Biophysical Society, Los Angeles, California, USA, 27 February - 2 March 2016
Zhang, Hailin,; Hu, Ronggui; Hu, Wenbao; Chen, Xibing; Liu, Zhengzhao; Zhou, Zijing; Cao, Xu; Huang, Pingbo Conference paper

2015 4

Cooperative control of blood compatibility and re-endothelialization by immobilized heparin and substrate topography
Acta Biomaterialia, v. 15, March 2015, p. 150-163
Ding, Yonghui; Yang, Meng; Yang, Zhilu; Luo, Rifang; Lu, Xiong; Huang, Nan; Huang, Pingbo; Leng, Yang Article
In vitro epithelial organoid generation induced by substrate nanotopography
Scientific Reports, v.5, March 2015, article number 9293
Shen, Yusheng; Hou, Youmin; Yao, Shuhuai; Huang, Pingbo; Yobas, Levent Article
Mechanical Characterization of Microengineered Epithelial Cysts Using Atomic Force Microscopy
MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, 2015, p. 173-175
Shen, Yusheng; Guan, Dongshi; Serien, Daniela; Takeuchi, Shoji; Tong, Penger; Huang, Pingbo; Yobas, Levent Conference paper
TRIP-Br1 is a novel adaptor protein for ubiquitinating and degrading multiple adenylyl cyclase isofroms by XIAP E3 ligase
9th Asian Biophysics Association (ABA) Symposium (ABA 2015), Hangzhou, China, 9-12 May 2015
Hu, Wenbao; Liu, Zhengzhao; Sun, Ying; Lam, Wai Kwan; Duan, Yuanyuan; Huang, Pingbo Conference paper

2014 4

Directing Vascular Cell Selectivity and Hemocompatibility on Patterned Platforms Featuring Variable Topographic Geometry and Size
ACS Applied Materials and Interfaces, v. 6, (15), August 2014, p. 12062-12070
Ding, Yonghui; Yang, Zhilu; Bi, Cathy W.C.; Yang, Meng; Xu, Sherry Li; Lu, Xiong; Huang, Nan; Huang, Pingbo; Leng, Yang Article
Modulation of Protein Adsorption, Vascular Cell Selectivity and Platelet Adhesion by Mussel-inspired Surface Functionalization
Journal of Materials Chemistry B: Materials for biology and medicine, v. 2, (24), June 2014, p. 3819-3829
Ding, Yonghui; Yang, Zhilu; Bi, Wenchuan; Yang, Meng; Zhang, Jingcheng; Xu, Sherry Li; Lu, Xiong; Huang, Nan; Huang, Pingbo; Leng, Yang Article
In vitro epithelial organoid generation induced by substrate nanotopography
International Symposium on Mechanobiology (ISMB 2014), Okayama University, Japan, 20-23 May 2014
Shen, Yusheng; Huang, Pingbo; Yobas, Levent Conference paper
Wild type and G551D CFTR control epithelial regulatory volume decrease as volume-sensitive channel
The Second International Symposium on Mechanobiology (ISMB 2014), Okayama, Japan, 20-23 May 2014
Xie, Changyan; Cao, Xu; Zhang, Wei; Sun, Ying; Hu, Wenbao; Wang, Yan; Huang, Pingbo Conference paper

2013 1

Organic Electrochemical Transistor Array for Recording Transepithelial Ion Transport of Human Airway Epithelial Cells
Advanced Materials, v. 25, (45), December 2013, p. 6575-6580
Yao, Chunlei; Xie, Changyan; Lin, Peng; Yan, Feng; Huang, Pingbo; Hsing, I-Ming Article

2012 6

A novel mechanism of control of NF kappa B activation and inflammation involving A(2B) adenosine receptors
Journal of cell science, v. 125, (19), 2012, p. 4507-4517
Sun, Ying; Duan, Yuanyuan; Eisenstein, Anna S.; Hu, Wenbao; Quintana, Adrien; Lam, Wai Kwan; Wang, Yan; Wu, Zhenguo; Ravid, Katya; Huang, Pingbo Article
Impaired CFTR-dependent amplification of FSH-stimulated estrogen production in cystic fibrosis and PCOS
The Journal of clinical endocrinology and metabolism, v. 97, (3), 2012, p. 923-932
Chen, H.; Guo, J.H.; Lu, Y.C.; Ding, G.L.; Yu, M.K.; Tsang, L.L.; Fok, K.L.; Liu, X.M.; Zhang, X.H.; Chung, Y.W.; Huang, P.; Huang, H.; Chan, H.C. Article
Keratin K18 Increases Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Surface Expression by Binding to Its C-terminal Hydrophobic Patch
Journal of Biological Chemistry, v. 287, (48), 2012, Nov, p. 40547-40559
Duan, Yuanyuan; Sun, Ying; Zhang, Fan; Zhang, Wei; Wang, Dong; Wang, Yan; Cao, Xu; Hu, Wenbao; Xie, Changyan; Cuppoletti, John; Magin, Thomas Michael; Wang, Haixia; Wu, Zhenguo; Li, Ning; Huang, Pingbo Article
Microcapillary-assisted dielectrophoresis for single-particle positioning
Lab on a chip, v. 12, (20), 2012, p. 4085-4092
Luo, Yuan; Cao, Xu; Huang, Pingbo; Yobas, Levent Article
Ligand-independent control of the NFkappaB pathway and inflammation by A2B adenosine receptors
Purine 2012, Fukuoka, Japan, May 31-Jun 2 2012
Sun, Ying; Duan, Yuanyuan; Eisenstein, Ann; Hu, Wenbao; Quintana, Adrien; Lam, Wai Kwan; Wang, Yan; Wu, Zhenguo; Ravid, Kataya; Huang, Pingbo Conference paper
Physical and functional interactins of A2B adenosine receptors with alpha-actinin-1
Purine 2012, Fukuoka, Japan, May 31-Jun 2 2012
Sun, Ying; Sun, Fengqiang; Ravid, Kataya; Huang, Pingbo Conference paper

2011 2

Defective CFTR-Dependent CREB Activation Results in Impaired Spermatogenesis and Azoospermia
PLoS ONE, v. 6, (5), May 2011
Xu, Wen Ming; Chen, Jing; Chen, Hui; Diao, Rui Ying; Fok, Kin Lam; Dong, Jian Da; Sun, Ting Ting; Chen, Wen Ying; Yu, Mei Kuen; Zhang, Xiao Hu; Tsang, Lai Ling; Lau, Ann; Shi, Qi Xian; Shi, Qing Hua; Huang, Ping Bo; Chan, Hsiao Chang Article
Mechanosensitivity of CFTR in transepithelial anion secretion and volume regulation
The 7th Asian Biophysics Association Symposium, Delhi, India, , 2011
Huang, Pingbo Conference paper

2010 4

Involvement of CFTR in oviductal HCO3- secretion and its effect on soluble adenylate cyclase-dependent early embryo development
Human reproduction, v. 25, (7), 2010, JUL, p. 1744-1754
Chen, Min Hui; Chen, Hui; Zhou, Zhen; Ruan, Ye Chun; Wong, Hau Yan; Lu, Yong Chao; Guo, Jing Hui; Chung, Yiu Wa; Huang, Ping Bo; Huang, He Feng; Zhou, Wen Liang; Chan, Hsiao Chang Article
Mechanosensitive Gating of CFTR
Nature Cell Biology, v. 12, (5), 2010, May, p. 507-512
Zhang, Wei Kevin; Wang, Dong; Duan, Yuanyuan; Loy, Michael M.T.; Chan, Hsiao Chang; Huang, Pingbo Article
Pathologically Activated Neuroprotection via Uncompetitive Blockade of N-Methyl-D-aspartate Receptors with Fast Off-rate by Novel Multifunctional Dimer Bis(propyl)-cognitin
Journal of biological chemistry, v. 285, (26), 2010, JUN 25, p. 19947-19958
Luo, Jialie; Li, Wenming; Zhao, Yuming; Fu, Hongjun; Ma, Dik-Lung; Tang, Jing; Li, Chaoying; Peoples, Robert W.; Li, Fushun; Wang, Qinwen; Huang, Pingbo; Xia, Jun; Pang, Yuanping; Han, Yifan Article
Keratin 18 increases CFTR surface expression by binding to its C-terminal hydrophobic patch
Joint Scientific Meeting of Hong Kong Society of Neurosceinces and The Biophysical Society of Hong Kong, HKU, Hong Kong, June 7-8, 2010
Duan, Yuanyuan; Zhang, Fan; Zhang, Wei; Wang, Dong; Wang, Yan; Sun, Ying; Yang, Pingfang; Cuppoletti, John; Magin, Thomas; Wang, Haixia; Wu, Zhenguo; Ning, Li; Huang, Pingbo Conference paper

2008 7

Adenosine promotes IL-6 release in airway epithelia
JOURNAL OF IMMUNOLOGY, v. 180, (6), 2008, MAR 15, p. 4173-4181
Sun, Ying; Wu, Fan; Sun, Fengqiang; Huang, Pingbo Article
Apical adenosine regulates basolateral Ca2+-activated potassium channels in human airway Calu-3 epithelial cells
American journal OF physiology-cell Physiology, v. 294, (6), 2008, JUN, p. C1443-C1453
Wang, Dong; Sun, Ying; Zhang, Wei; Huang, Pingbo Article
EGY1 plays a role in regulation of endodermal plastid size and number that are involved in ethylene-dependent gravitropism of light-grown Arabidopsis hypocotyls
Plant molecular biology, v. 66, (4), 2008, MAR, p. 345-360
Guo, Di; Gao, Xiaorong; Li, Hao; Zhang, Tao; Chen, Gu; Huang, Pingbo; An, Lijia; Li, Ning Article
Functional coupling of Gs and CFTR is independent of their association with lipid rafts in epithelial cells
Pflügers Archiv - European Journal of Physiology, v. 456, (5), 2008, AUG, p. 929-938
Wang, Dong; Wang, Wen; Duan, Yuanyuan; Sun, Ying; Wang, Yan; Huang, Pingbo Article
Intracellular spatial control of fluorescent magnetic nanoparticles
Journal of the American Chemical Society, v. 130, (12), 2008, MAR 26, p. 3710+
Gao, Jinhao; Zhang, Wei; Huang, Pingbo; Zhang, Bei; Zhang, Xixiang; Xu, Bing Article
A2B Adenosine Receptor Negatively Regulates NFB Activation through Physical Interaction with p105
48th Annual Meeting of the American Society for Cell Biology, The Moscone Center, San Francisco, California (USA), 13-17 Dec 2008
Sun, Y.; Lam, W.; Duan, Y.; Quintana, A.; Sun, F.; Wu, Z.; Huang, P. Conference paper
The C-Terminal Hydrophobic Patch of CFTR Interacts with Cytoskeletal Keratin 18 for Stable Surface Expression
48th Annual Meeting of the American Society for Cell Biology, The Moscone Center, San Francisco, California (USA), 13-17 Dec 2008
Duan, Y.; Zhang, F.; Wang, D.; Zhang, W.; Sun, Y.; Yang, P.; Cuppoletti, J.; Wang, H.; Wu, Z.; Magin, T.; Huang, P. Conference paper

2007 1

Novel dimeric bis(7)-tacrine proton-dependently inhibits NMDA-activated currents
Biochemical and biophysical research communications, v. 361, (2), 2007, SEP 21, p. 505-509
Luo, Jialie; Li, Wenming; Liu, Yuwei; Zhang, Wei; Fu, Hongjun; Lee, Nelson T.K.; Yu, Hua; Pang, Yuanping; Huang, Pingbo; Xia, Jun; Li, Zhi-Wang; Li, Chaoying; Han, Yifan Article

2006 2

Micromolding of PDMS scaffolds and microwells for tissue culture and cell patterning: A new method of microfabrication by the self-assembled micropatterns of diblock copolymer micelles
Polymer, v. 47, (14), 2006, JUN 28, p. 5124-5130
Mi, Yongli; Chan, Yannie; Trau, Dieter; Huang, Pingbo; Chen, Erqiang Article
Cytoskeletal Keratin 18 Regulates the Cell Surface Expression of CFTR Channel via Direct Binding
4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS 2006), Cheung Kung Hai Conference Centre, Hong Kong City (Hong Kong-S.A.R of China), 30 Nov-2 Dec 2006
Duan, Yuanyuan; Yang, Pingfan; Zhang, Wei; Sun, Ying; Wang, Dong; Huang, Pingbo Conference paper

2005 2

Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium
Journal of Biological Chemistry, v. 280, (9), 2005, p. 7997-8003
Barnes, A.P.; Livera, G.; Huang, P.; Sun, C.; O'Neal, W.K.; Conti, M.; Stutts, M.J.; Milgram, S.L. Article
Regulation of CFTR channels by HCO₃^?-sensitive soluble adenylyl cyclase in human airway epithelial cells
American journal OF physiology-cell Physiology, v. 289, (5), 2005, NOV, p. C1145-C1151
Wang, Yan; Lam, Chak Sum; Wu, Fan; Wang, Wen; Duan, Yuanyuan; Huang, Pingbo Article

2004 3

Local regulation of cystic fibrosis transmembrane regulator and epithelial sodium channel in airway epithelium.
Proc Am Thorac Soc, v. 1, (1), 2004, p. 33-37
Huang, P.; Gilmore, E.; Kultgen, P.; Barnes, P.; Milgram, S.; Stutts, M.J. Article
Voltage-dependent anion channel-1 (VDAC-1) contributes to ATP release and cell volume regulation in murine cells
Journal of General Physiology, v. 124, (5), 2004, p. 513-526
Okada, S.F.; O'Neal, W.K.; Huang, P.; Nicholas, R.A.; Ostrowski, L.E.; Craigen, W.J.; Lazarowski, E.R.; Boucher, R.C. Article
Contribution of Vdac (Voltage-Dependent Anion Channel) to Epithelial ATP Release And Cell Volume Regulation
Purines 2004, Chapel Hill, North Carolina, USA
Okada, Seiko F.; O'neal, Wanda K.; Huang, Pingbo; Nicholas, Robert A.; Craigen, William J.; Ostrowski, Lawrence E.; Lazarowski, Eduardo R.; Boucher, Richard C. Conference paper

2001 1

Compartmentalized autocrine signaling to cystic fibrosis transmembrane conductance regulator at the apical membrane of airway epithelial cells
Proceedings of the National Academy of Sciences of the United States of America, 98(24), 14120-14125
Huang, P.; Lazarowski, E.R.; Tarran, R.; Milgram, S.L.; Boucher, R.C.; Stutts, M.J. Article

2000 1

PKA holoenzyme is functionally coupled to CFTR by AKAPs
Am. J. Physiol, 278, C417-C422
Huang, P.; Trotter, K.; Boucher, R.C.; Milgram, S.L.; Stutts, M.J. Article

1998 1

Lysophosphatidylglycerol: a novel effective detergent for solubilizing and purifying the cystic fibrosis transmembrane conductance regulator
Anal Biochem, v. 259, 1998, p. 89-97
Huang, Pingbo; Liu, Q.; Scarborough, GA Article

1996 1

Functional expression of the cystic fibrosis transmembrane conductance regulator in yeast
Biochim Biophys Acta (Biomembranes), v. 1281, 1996, p. 80-90
Huang, Pingbo; Stroffekova, K.; Cuppoletti, J.; Mahanty, SK; Scarborough, GA Article

1993 1

Stimulus-associated protein in gastric parietal cell detected using antimelittin antibody
Am. J. Physiol, v. 264, 1993, p. G637-G644
Cuppoletti, J.; Huang, Pingbo; Kaetzel, M.A.; Malinowska, D.H. Article

1992 3

Structure-function relationships in the interaction of amphipathic helical polypeptides with the gastric H/K ATPase
Annals of the New York Academy of Sciences, v. 671, p. 443-445, 1992
Cuppoletti, J.; Chernyak, B.V.; Huang, Pingbo; Malinowska, D.H. Article
The role of afferent C fibers in electroacupuncture of "Zusanli" point activating nucleus raphe magnus
Chinese J. Physiol. Sci, v. 8, (3), 1992, p. 257-267
Liu, X.; Jiang, M.; Huang, Pingbo; Zou, T. Article
Bioactive peptide inhibitors and an endogenous pariteal cell protein interactions with the gastric H/K ATPase
NATO Advanced Research Conference Held in York, England, 1992
Cuppoletti, J.; Huang, Pingbo; Malinowska, D.H. Conference paper


No Publications






Teaching Assignment

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2021-22 Winter 0 2021-22 Fall 3 2020-21 Summer 0 2020-21 Spring 4 2020-21 Winter 1 2020-21 Fall 6

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LIFS4971 Biochemistry and Cell Biology Project Research I
LIFS6113E Current Topics in Biochemistry and Biophysics
SCIE4500 IRE Research Project II


LIFS3020 Molecular and Cellular Biology II
LIFS3040 Animal Physiology
LIFS4981 Biochemistry and Cell Biology Project Research II
LIFS6660 Molecular Medicine


LIFS6660 Molecular Medicine


BIPH3010 Advanced Biological Physics
LIFS4961 Biochemistry and Cell Biology Capstone Project
LIFS4963 Biotechnology Capstone Project
LIFS4971 Biochemistry and Cell Biology Project Research I
LIFS6113D Current Topics in Biochemistry and Biophysics
SCIE3900 International Research Experience


No Teaching Assignments


No Teaching Assignments






Research Postgraduate (RPG) Supervision From January 2019 to December 2022 (As of 30 January 2022)

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All Supervisions Current RPGs Graduated RPGs

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Current RPGs

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Doctor of Philosophy FENG, Wanying
Bioscience and Biomedical Engineering( 2021 - )

LU, Yiying
Life Science( 2021 - )

CHEN, Yixuan
Bioengineering( 2018 - )

TIAN, Ye
Life Science( 2018 - )

YANG, Yingkun
Life Science( 2018 - )

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Master of Philosophy LI, Yihao
Bioscience and Biomedical Engineering( 2021 - )

LUI, Sin Tung
Life Science( 2021 - )

LI, Yulin
Life Science( 2020 - )

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Graduated RPGs

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Doctor of Philosophy ZHAO, Qirui
Life Science( Completed in 2021 )

CHEN, Xibing
Life Science( Completed in 2019 )

LI, Xiaofen
Bioengineering( Completed in 2019 )

YU, Xiaojie
Life Science( Completed in 2019 )

ZHOU, Zijing
Life Science( Completed in 2019 )

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Master of Philosophy WONG, Yuk Ming
Life Science( Completed in 2021 )

CHENG, Kar On
Life Science( Completed in 2020 )









ProjectsFrom January 2020 to December 2022

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All Projects 11 Leading Projects 7 Participating Projects 4

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Ectopic expression and functional study of full-length human TMC1 in the absence or presence of TMIE


人全长TMC1单独或和TMIE一起的外源表达和功能研究 Leading


RGC - General Research Fund


Project Team (HKUST)
HUANG Pingbo (Lead)
PARK Hyo Keun


2021 -




Probing emergent mechanics of living matter: From single cells to epithelial


探索生命物质的新兴力学：从单细胞到表皮单细胞层 Participating


RGC - General Research Fund


Project Team (HKUST)
TONG Penger (Lead)
HUANG Pingbo


2021 -




Functional characterization of the splicing isoforms of Tmc1 and Lhfpl5 genes in mouse auditory hair cells


小鼠内耳听毛细胞TMC1和LHFPL5替代拼接亚型的功能研究 Leading


RGC - General Research Fund


Project Team (HKUST)
HUANG Pingbo (Lead)
WANG Jiguang


2020 -




Working mechanisms of TMC1 in auditory hair cells


TMC1 在听觉毛细胞中的工作机制 Leading


National Natural Science Foundation of China / Research Grants Council Joint Research Scheme


Project Team (HKUST)
HUANG Pingbo (Lead)


2019 -




Physical and functional interactions of TMC1 and Rab37 in auditory hair cells


TMC1和Rab37在听觉毛细胞中物理上和功能上之相互作用 Leading


RGC - General Research Fund


Project Team (HKUST)
HUANG Pingbo (Lead)


2018 - 2021




Neurotransmitter release and receptor diffusion dynamics during inhibitory synaptic transmission


抑制性突触传递中神经递质释放和受体扩散动力学研究 Participating


ANR / RGC Joint Research Scheme


Project Team (HKUST)
PARK Hyo Keun (Lead)
HUANG Pingbo


2018 - 2021




Explore the regulation of calcium-activated chloride channel ANO1 by E3 ligase TRIM21, and its role in tumorigenesis


泛素连接酶TRIM21对钙激活通道ANO1的调节及该调节对肿瘤形成的影响 Leading


Shenzhen Science and Technology Innovation Committee


Project Team (HKUST)
HUANG Pingbo (Lead)


2018 - 2020




FLRT1 and FLRT3 in auditory hair cells: distinct roles in the development and maintenance of the hair bundle and their interactions with TMC1


FLRT1和FLRT3在听毛细胞发育及维持听毛形态中的不同功能以及其与TMC1 的相互作用 Leading


RGC - General Research Fund


Project Team (HKUST)
HUANG Pingbo (Lead)
GUO Yusong


2017 - 2021




Robust Microsystems for a High-Throughput Precision Intracellular Delivery


用於高通量精确细胞内转运的可靠微系统 Participating


RGC - General Research Fund


Project Team (HKUST)
YOBAS Levent (Lead)
HUANG Pingbo


2017 - 2021




State Key Laboratory of Molecular Neuroscience (The Hong Kong University of Science and Technology)


分子神经科学国家重点实验室（香港科技大学） Participating


Innovation and Technology Fund


Project Team (HKUST)
IP Nancy Yuk-Yu (Lead)
CHOW King Lau
CHUNG Kenny K
DAI Wei Min
GUO Zhihong
HUANG Pingbo
LIANG Chun
MILLER Andrew Leitch
POON Randy Yat Choi
QI Robert Zhong
TSIM Karl Wah Keung
WEN Zilong
WONG Joseph Tin Yum
WONG Yung Hou
WU Zhenguo
ZHU Guang


2011 -




Investigation of the role of soluble AC in the modulation of CFTR Leading


University of Cincinnati


Project Team (HKUST)
HUANG Pingbo (Lead)


2006 - 2021