Tom CHEUNG
张晓东
PhD in Biochemistry
University of Colorado at Boulder, 2006

S H Ho Associate Professor of Life Science

Associate Professor
Division of Life Science

Director of HKUST-BGI Joint Research Center

Director of HKUST-Nan Fung Life Sciences Joint Laboratory

Associate Director of Biosciences Central Research Facility

Associate Director of HKUST-Shanghai Sixth People's Hospital Joint Research Center for Brain Science



(852) 2358 7306
tcheung@ust.hk
Room 5522
Personal Web

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Google Scholar
WtsX8AsAAAAJ

ORCID
0000-0003-0796-5406

Scopus ID
36847497100




Research Interest Publications Projects Teaching Assignment RPG Supervision Space used




Research Interest

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Aging
Muscle stem cells
Single particle / molecule / cell studies
Muscular dystrophy
Stem cell biology



Publications

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All Years 46 2022 0 2021 3 2020 5 2019 5 2018 4 2017 3 2016 26

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2021 3

Deciphering the chromatin organization and dynamics for muscle stem cell function
Current Opinion in Cell Biology, v. 73, December 2021, p. 124-132
Dong, Anqi; Cheung, Hiu Tung Tom Article
Nuclear receptors NHR-49 and NHR-79 promote peroxisome proliferation to compensate for aldehyde dehydrogenase deficiency in C. elegans
PLOS Genetics, v. 17, (7), July 2021, article number e1009635
Zeng, Lidan; Li, Xuesong; Preusch, Christopher Brandon; He, Jiawei; Xu, Ningyi; Cheung, Hiu Tung; Qu, Jianan; Mak, Ho Yi Article
Stem cell quiescence: the challenging path to activation
Development (Cambridge, England), v. 148, (3), February 2021, article number dev165084
Urbán, Noelia; Cheung, Hiu Tung Article

2020 5

A long noncoding RNA, LncMyoD, modulates chromatin accessibility to regulate muscle stem cell myogenic lineage progression
Proceedings of the National Academy of Sciences of the United States of America, v. 117, (51), December 2020, p. 32464-32475
Dong, Anqi; Preusch, Christopher Brandon; So, Wai Kin; Lin, Kangning; Luan, Shaoyuan; Yi, Ran; Wong, Wing Chiu; Wu, Zhenguo; Cheung, Hiu Tung Article
Dek Modulates Global Intron Retention during Muscle Stem Cells Quiescence Exit
Developmental Cell, v. 53, (6), June 2020, p. 661-676.e6
Yue, Lu; Wan, Raymond; Luan, Shaoyuan; Zeng, Wenshu; Cheung, Hiu Tung Article
High-contrast, fast chemical imaging by coherent Raman scattering using a self-synchronized two-colour fibre laser
Light: Science & Applications, v. 9, (1), February 2020, article number 25
Kong, Cihang; Pilger, Christian; Hachmeister, Henning; Wei, Xiaoming; Cheung, Tom H.; Lai, Cora S. W.; Lee, Nikki P.; Tsia, Kevin. K.; Wong, Kenneth K. Y.; Huser, Thomas Article
IL-33-PU.1 Transcriptome Reprogramming Drives Functional State Transition and Clearance Activity of Microglia in Alzheimer’s Disease
Cell Reports, v. 31, (3), April 2020, article number 107530
Lau, Shun Fat; Chen, Congping; Fu, Wing Yu; Qu, Jianan; Cheung, Hiu Tung; Fu, Kit Yu; Ip, Nancy Yuk-yu Article
Protocol for Isolation and Characterization of In Situ Fixed Quiescent Muscle Stem Cells
STAR Protocols, v. 1, (3), December 2020, article number 100128
Yue, Lu; Cheung, Hiu Tung Article

2019 5

High-Dimensional Single-Cell Cartography Reveals Novel Skeletal Muscle-Resident Cell Populations
Molecular cell, v. 74, (3), May 2019, p. 609-621.e6
Giordani, Lorenzo; He, Jiawei; Negroni, Elisa; Sakai, Hiroshi; Law, Yiu Chun; Siu, Men Yi Mona; Wan, Raymond; Corneau, Aurélien; Tajbakhsh, Shahragim; Cheung, Hiu Tung; Le grand, Fabien Article
Hormones Induce the Formation of Luminal-derived Basal Cells in the Mammary Gland
Cell Research, v. 29, (3), March 2019, p. 206-220
Song, Wenqian; Wang, Ran; Jiang, Weimin; Yin, Qi; Peng, Guangdun; Yang, Ruikai; Yu, Qing Cissy; Chen, Jianfeng; Li, Jingsong; Cheung, Hiu Tung; Jing, Naihe; Zeng, Yi Arial Article
YY1 Regulates Skeletal Muscle Regeneration Through Controlling Metabolic Reprogramming of Satellite Cells
EMBO Journal, v. 38, (10), May 2019, article number e99727
Chen, Fengyuan; Zhou, Jiajian; Li, Yuying; Zhao, Yu; Yuan, Jie; Cao, Yang; Wang, Lijun; Zhang, Zongkang; Zhang, Baoting; Wang, Chi Chiu; Cheung, Tom H.; Wu, Zhenguo; Wong, Carmen Chak‐Lui; Sun, Hao; Wang, Huating Article
α2-chimaerin is essential for neural stem cell homeostasis in mouse adult neurogenesis
Proceedings of the National Academy of Sciences of the United States of America, v. 116, (27), June 2019, p. 13651-13660
Su, Yiting; Lau, Shun Fat; Ip, P.K. Jacque; Cheung, Kit; Cheung, Hiu Tung; Fu, Kit Yu; Ip, Nancy Yuk-yu Article
IL-33-dependent transcriptome reprogramming drives functional state transition and clearance activity of microglia in Alzheimer’s disease
VIB Conference Series: The Brain Mosaic: Cellular heterogeneity in the CNS, Leuven, Belgium, 10-11 October 2019
Lau, Shun Fat; Chen, Congping; Fu, Wing Yu; Qu, Jianan; Cheung, Hiu Tung; Fu, Kit Yu; Ip, Nancy Yuk-Yu Conference paper

2018 4

Impaired notch signaling leads to a decrease in p53 activity and mitotic catastrophe in aged muscle stem cells
Cell Stem Cell, v. 23, (4), October 2018, p. 544-556.e4
Liu, Ling; Charville, Gregory W.; Cheung, Tom H.; Yoo, Bryan; Santos, Pauline J.; Schroeder, Matthew; Rando, Thomas A. Article
Large-Scale Expansion of Human iPSC-Derived Skeletal Muscle Cells for Disease Modeling and Cell-Based Therapeutic Strategies
Stem Cell Reports, v. 10, (6), June 2018, p. 1975-1990
van der Wal, Erik; Herrero-Hernandez, Pablo; Wan, Raymond; Broeders, Mike; in 't Groen, Stijn L.M.; van Gestel, Tom J.M.; van IJcken, Wilfred F.J.; Cheung, Hiu Tung; van der Ploeg, Ans T.; Schaaf, Gerben J.; Pijnappel, W.W.M.Pim Article
Molecular Regulation of Cellular Quiescence: A Perspective from Adult Stem Cells and Its Niches
Methods in Molecular Biology, v. 1686, 2018, p. 1-25, Cellular Quiescence: Methods and Protocols
So, Wai Kin; Cheung, Tom Article
p110α of PI3K is Necessary and Sufficient for Quiescence Exit in Adult Muscle Satellite Cells
EMBO journal, v. 37, (8), April 2018, article number e98239
Wang, Gang; Zhu, Han; Situ, Chenghao; Han, Lifang; Yu, Youqian; Cheung, Tom H.; Liu, Kai; Wu, Zhenguo Article

2017 3

A Molecular Switch Regulating Cell Fate Choice between Muscle Progenitor Cells and Brown Adipocytes
Developmental Cell, v. 41, (4), May 2017, p. 382-391.e5
An, Yitai; Wang, Gang; Diao, Yarui; Long, Yanyang; Fu, Xinrong; Weng, Mingxi; Zhou, Liang; Sun, Kun; Cheung, Tom H.; Ip, Nancy Yuk-yu; Sun, Hao; Wang, Huating; Wu, Zhenguo Article
Anemoside A3 Ameliorates Experimental Autoimmune Encephalomyelitis by Modulating T Helper 17 Cell Response
PLoS ONE, v. 12, (7), July 2017, article number e0182069
Ip, Fanny; Ng, Yupong; Or, Terry Cho Tsun; Sun, Peiran; Fu, Guangmiao; Li, Jessica Y.H.; Ye, Wencai; Cheung, Tom H.; Ip, Nancy Y.Y. Article
Compact fs Ytterbium Fiber Laser at 1010 nm for Biomedical Applications
Biomedical Optics Express, v. 8, (11), November 2017, article number 300964, p. 4921-4932
Kong, Cihang; Pilger, Christian; Hachmeister, Henning; Wei, Xiaoming; Cheung, Tom H.; Lai, Cora S. W.; Huser, Thomas; Tsia, Kevin. K.; Wong, Kenneth K. Y. Article

2016 8

IL-33 Ameliorates Alzheimer’s Disease-like Pathology and Cognitive Decline
Proceedings of the National Academy of Sciences of the United States of America, v. 113, (19), May 2016, p. 2705-2713
Fu, Kit Yu; Hung, Kwok Wang; Yuen, Yat Fai; Zhou, Xiaopu; Mak, Deejay S.Y.; Chan, Chi Wai; Cheung, Tom H.; Zhang, Baorong; Fu, Wing Yu; Liew, Foo Y.; Ip, Nancy Yuk-yu Article
Intronic Polyadenylation of PDGFRα in Resident Stem Cells Attenuates muscle Fibrosis
Nature, v. 540, (7632), December 2016, p. 276-279
Mueller, Alisa A.; Van Velthoven, Cindy T.; Fukumoto, Kathryn D.; Cheung, Tom H.; Rando, Thomas A. Article
STAT3 Regulates Self-Renewal of Adult Muscle Satellite Cells during Injury-Induced Muscle Regeneration
Cell Reports, v. 16, (8), 23 August 2016, p. 2102-2115
Zhu, Han; Xiao, Fang; Wang, Gang; Wei, Xiuqing; Jiang, Lei; Chen, Yan; Zhu, Lin; Wang, Haixia; Diao, Yarui; Wang, Huating; Ip, Nancy Y Y; Cheung, Tom H.; Wu, Zhenguo Article
The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery
Cell, v. 167, (5), November 2016, p. 1145-1149
Stunnenberg, Hendrik G.; The International Human Epigenome Consortium; Cheung, Tom H.; Hirst, Martin Article
IL-33 Ameliorates Alzheimer’s Disease-like Pathology and Cognitive Decline
The 46th Annual Meeting of the Society for Neuroscience, San Diego, USA, 12 - 16 November 2016
Fu, Kit Yu; Hung, Kwok Wang; Yuen, Matthew Ming Fai; Zhou, Xiaopu; Mak, Deejay S.Y.; Chan, I.C.W.; Cheung, Tom H.; Zhang, Baorong; Fu, Wing Yu; Liew, Foo Y.; Ip, Nancy Yuk-yu Conference paper
IL-33 ameliorates cognitive deficits and amyloid pathology in an Alzheimer’s disease-like mouse model
Molecular & Cellular Neurobiology, Gordon Research Conference, The Hong Kong University of Science and Technology, June, 2016
Fu, Kit Yu; Hung, Kwok Wang; Yuen, M.Y.F.; Zhou, Xiaopu; Mak, D.S.Y.; Chan, I.C.W.; Cheung, Tom; Zhang, B; Fu, Wing Yu; Liew, F.Y.; Ip, Nancy Yuk-yu Conference paper
IL-33 modulates microglial innate immunity in an Alzheimer’s disease-like mouse model
Molecular & Cellular Neurobiology, Gordon Research Conference, Hong Kong, 12-17 June 2016
Zhou, Xiaopu; Ip, Nancy Yuk-yu; Cheung, Tom; Liew, F.Y.; Chan, I.C.W.; Mak, D.S.Y.; Yuen, M.Y.F.; Hung, Kwok Wang; Fu, Kit Yu; Fu, Wing Yu Conference paper
IL-33 Modulates the Inflammatory Response in the Brains of Alzheimer’s disease mouse model
The 46th Annual Meeting of the Society for Neuroscience, San Diego, USA, 12-16 November 2016
Fu, Wing Yu; Fu, Kit Yu; Hung, Kwok Wang; Yuen, Matthew Ming Fai; Zhou, Xiaopu; Mak, D.S.Y.; Chan, I.C.W.; Liew, F.Y.; Cheung, Tom H.; Ip, Nancy Yuk-yu Conference paper

2015 2

Ex Vivo Expansion and In Vivo Self-Renewal of Human Muscle Stem Cells
Stem Cell Reports, v. 5, (4), October 2015, p. 621-632
Charville, Gregory W.; Cheung, Tom H.; Yoo, Bryan; Santos, Pauline J.; Lee, Gordon K.; Shrager, Joseph B.; Rando, Thomas A. Article
Isolation of skeletal muscle stem cells by fluorescence-activated cell sorting
Nature Protocols, v. 10, (10), October 2015, p. 1612-1624
Liu, Ling; Cheung, Tom Hiu Tung; Charville, Gregory William; Rando, Thomas A. Article

2013 3

All's well that ends well: Alternative polyadenylation and its implications for stem cell biology
Current Opinion in Cell Biology, v. 25, (2), 2013, p. 222-232
Mueller, A.A.; Cheung, Tom Hiu Tung; Rando, T.A. Article
Chromatin Modifications as determinants of muscle stem cell quiescence and chronological aging
Cell Reports, v. 4, (1), July 2013, p. 189-204
Liu, Ling; Cheung, Tom H.; Charville, Gregory W.; Hurgo, Bernadette Marie Ceniza; Leavitt, Tripp; Shih, Johnathan; Brunet, Anne; Rando, Thomas A. Article
Molecular regulation of stem cell quiescence
Nature Reviews Molecular Cell Biology, v. 14, (6), June 2013, p. 329-340
Cheung, Tom Hiu Tung; Rando, Thomas A. Article

2012 3

Alternative polyadenylation mediates microRNA regulation of muscle stem cell function
Cell stem cell, v. 10, (3), 2012, p. 327-336
Boutet, S.C.; Cheung, Tom Hiu Tung; Quach, N.L.; Liu, L.; Prescott, S.L.; Edalati, A.; Iori, K.; Rando, T.A. Article
Maintenance of muscle stem-cell quiescence by microRNA-489
Nature, v. 482, (7386), 2012, p. 524-528
Cheung, Tom Hiu Tung; Quach, N.L.; Charville, G.W.; Liu, L.; Park, L.; Edalati, A.; Yoo, B.; Hoang, P.; Rando, T.A. Article
Notch signaling is necessary to maintain quiescence in adult muscle stem cells
Stem cells, v. 30, (2), 2012, p. 232-242
Bjornson, C.R.R.; Cheung, Tom Hiu Tung; Liu, L.; Tripathi, P.V.; Steeper, K.M.; Rando, T.A. Article

2011 1

Remodeling the cardiac transcriptional landscape with diet
Physiological genomics, v. 43, (12), 2011, p. 772-780
Luczak, E.D.; Barthel, K.K.B.; Stauffer, B.L.; Konhilas, J.P.; Cheung, Tom Hiu Tung; Leinwand, L.A. Article

2007 2

Identifying pattern-defined regulatory islands in mammalian genomes
Proceedings of the National Academy of Sciences of the United States of America, v.104 , (24), 2007, Jun, p. 10116-10121
Cheung, Tom Hiu Tung; Barthel, K.K.B.; Yin, L.K.; Liu, X. Article
Systematic Identification of C.?elegans miRISC Proteins, miRNAs, and mRNA Targets by Their Interactions with GW182 Proteins AIN-1 and AIN-2
Molecular cell, v. 28, (4), 2007, p. 598-613
Zhang, L.; Ding, L.; Cheung, Tom Hiu Tung; Dong, M.Q.; Chen, J.; Sewell, A.K.; Liu, X.; Yates III, J.R.; Han, M. Article

2006 2

Global gene expression analysis of ERK5 and ERK1/2 signaling reveals a role for HIF-1 in ERK5-mediated responses
Journal of Biological Chemistry, v. 281, (30), 2006, p. 20993-21003
Schweppe, RE; Cheung, Tom Hiu Tung; Ahn, NG Article
Unraveling transcriptional control and cis-regulatory codes using the software suite GeneACT
Genome Biology, v. 7, (10), 2006
Cheung, Tom Hiu Tung; Kwan, YL; Hamady, M.; Liu, X. Article

2005 3

A method of mapping protein sumoylation sites by mass spectrometry using a modified small ubiquitin-like modifier 1 (SUMO-1) and a computational program
Molecular & cellular proteomics, v. 4, (10), October 2005, p. 1626-1636
Knuesel, M.; Cheung, Tom H.; Hamady, M.; Barthel, KKB; Liu, XD Article
Does protein structure influence trypsin miscleavage?
IEEE Engineering in Medicine and Biology Magazine, v. 24, (3), 2005, p. 58-66
Hamady, M.; Cheung, Tom Hiu Tung; Tufo, H.; Knight, R. Article
Key challenges in proteomics and proteoinformatics
IEEE Engineering in Medicine and Biology Magazine, v. 24, (3), 2005, p. 34-40
Hamady, M.; Cheung, Tom Hiu Tung; Resing, K.; Cios, K.J.; Knight, R. Article

2004 2

Control of cell cycle-dependent degradation of c-Ski proto-oncoprotein by Cdc34
Oncogene, v. 23, (33), 2004, p. 5643-5653
Macdonald, M.; Wan, Y.; Wang, W.; Roberts, E.; Cheung, Tom Hiu Tung; Erickson, R.; Knuesel, MT; Liu, X. Article
Improving reproducibility and sensitivity in identifying human proteins by shotgun proteomics
Analytical chemistry, v. 76, (13), July 2004, p. 3556-3568
Resing, KA; Meyer-Arendt, K.; Mendoza, AM; Aveline-Wolf, LD; Jonscher, KR; Pierce, KG; Old, WM; Cheung, Tom Hiu Tung; Russell, S.; Wattawa, JL; Goehle, GR; Knight, RD; Ahn, NG Article


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Article 3

Deciphering the chromatin organization and dynamics for muscle stem cell function
Current Opinion in Cell Biology, v. 73, December 2021, p. 124-132
Dong, Anqi; Cheung, Hiu Tung Tom
Nuclear receptors NHR-49 and NHR-79 promote peroxisome proliferation to compensate for aldehyde dehydrogenase deficiency in C. elegans
PLOS Genetics, v. 17, (7), July 2021, article number e1009635
Zeng, Lidan; Li, Xuesong; Preusch, Christopher Brandon; He, Jiawei; Xu, Ningyi; Cheung, Hiu Tung; Qu, Jianan; Mak, Ho Yi
Stem cell quiescence: the challenging path to activation
Development (Cambridge, England), v. 148, (3), February 2021, article number dev165084
Urbán, Noelia; Cheung, Hiu Tung


Expand All Collapse All


Article 5

A long noncoding RNA, LncMyoD, modulates chromatin accessibility to regulate muscle stem cell myogenic lineage progression
Proceedings of the National Academy of Sciences of the United States of America, v. 117, (51), December 2020, p. 32464-32475
Dong, Anqi; Preusch, Christopher Brandon; So, Wai Kin; Lin, Kangning; Luan, Shaoyuan; Yi, Ran; Wong, Wing Chiu; Wu, Zhenguo; Cheung, Hiu Tung
Dek Modulates Global Intron Retention during Muscle Stem Cells Quiescence Exit
Developmental Cell, v. 53, (6), June 2020, p. 661-676.e6
Yue, Lu; Wan, Raymond; Luan, Shaoyuan; Zeng, Wenshu; Cheung, Hiu Tung
High-contrast, fast chemical imaging by coherent Raman scattering using a self-synchronized two-colour fibre laser
Light: Science & Applications, v. 9, (1), February 2020, article number 25
Kong, Cihang; Pilger, Christian; Hachmeister, Henning; Wei, Xiaoming; Cheung, Tom H.; Lai, Cora S. W.; Lee, Nikki P.; Tsia, Kevin. K.; Wong, Kenneth K. Y.; Huser, Thomas
IL-33-PU.1 Transcriptome Reprogramming Drives Functional State Transition and Clearance Activity of Microglia in Alzheimer’s Disease
Cell Reports, v. 31, (3), April 2020, article number 107530
Lau, Shun Fat; Chen, Congping; Fu, Wing Yu; Qu, Jianan; Cheung, Hiu Tung; Fu, Kit Yu; Ip, Nancy Yuk-yu
Protocol for Isolation and Characterization of In Situ Fixed Quiescent Muscle Stem Cells
STAR Protocols, v. 1, (3), December 2020, article number 100128
Yue, Lu; Cheung, Hiu Tung


Expand All Collapse All


Article 4

High-Dimensional Single-Cell Cartography Reveals Novel Skeletal Muscle-Resident Cell Populations
Molecular cell, v. 74, (3), May 2019, p. 609-621.e6
Giordani, Lorenzo; He, Jiawei; Negroni, Elisa; Sakai, Hiroshi; Law, Yiu Chun; Siu, Men Yi Mona; Wan, Raymond; Corneau, Aurélien; Tajbakhsh, Shahragim; Cheung, Hiu Tung; Le grand, Fabien
Hormones Induce the Formation of Luminal-derived Basal Cells in the Mammary Gland
Cell Research, v. 29, (3), March 2019, p. 206-220
Song, Wenqian; Wang, Ran; Jiang, Weimin; Yin, Qi; Peng, Guangdun; Yang, Ruikai; Yu, Qing Cissy; Chen, Jianfeng; Li, Jingsong; Cheung, Hiu Tung; Jing, Naihe; Zeng, Yi Arial
YY1 Regulates Skeletal Muscle Regeneration Through Controlling Metabolic Reprogramming of Satellite Cells
EMBO Journal, v. 38, (10), May 2019, article number e99727
Chen, Fengyuan; Zhou, Jiajian; Li, Yuying; Zhao, Yu; Yuan, Jie; Cao, Yang; Wang, Lijun; Zhang, Zongkang; Zhang, Baoting; Wang, Chi Chiu; Cheung, Tom H.; Wu, Zhenguo; Wong, Carmen Chak‐Lui; Sun, Hao; Wang, Huating
α2-chimaerin is essential for neural stem cell homeostasis in mouse adult neurogenesis
Proceedings of the National Academy of Sciences of the United States of America, v. 116, (27), June 2019, p. 13651-13660
Su, Yiting; Lau, Shun Fat; Ip, P.K. Jacque; Cheung, Kit; Cheung, Hiu Tung; Fu, Kit Yu; Ip, Nancy Yuk-yu

Conference paper 1

IL-33-dependent transcriptome reprogramming drives functional state transition and clearance activity of microglia in Alzheimer’s disease
VIB Conference Series: The Brain Mosaic: Cellular heterogeneity in the CNS, Leuven, Belgium, 10-11 October 2019
Lau, Shun Fat; Chen, Congping; Fu, Wing Yu; Qu, Jianan; Cheung, Hiu Tung; Fu, Kit Yu; Ip, Nancy Yuk-Yu


Expand All Collapse All


Article 4

Impaired notch signaling leads to a decrease in p53 activity and mitotic catastrophe in aged muscle stem cells
Cell Stem Cell, v. 23, (4), October 2018, p. 544-556.e4
Liu, Ling; Charville, Gregory W.; Cheung, Tom H.; Yoo, Bryan; Santos, Pauline J.; Schroeder, Matthew; Rando, Thomas A.
Large-Scale Expansion of Human iPSC-Derived Skeletal Muscle Cells for Disease Modeling and Cell-Based Therapeutic Strategies
Stem Cell Reports, v. 10, (6), June 2018, p. 1975-1990
van der Wal, Erik; Herrero-Hernandez, Pablo; Wan, Raymond; Broeders, Mike; in 't Groen, Stijn L.M.; van Gestel, Tom J.M.; van IJcken, Wilfred F.J.; Cheung, Hiu Tung; van der Ploeg, Ans T.; Schaaf, Gerben J.; Pijnappel, W.W.M.Pim
Molecular Regulation of Cellular Quiescence: A Perspective from Adult Stem Cells and Its Niches
Methods in Molecular Biology, v. 1686, 2018, p. 1-25, Cellular Quiescence: Methods and Protocols
So, Wai Kin; Cheung, Tom
p110α of PI3K is Necessary and Sufficient for Quiescence Exit in Adult Muscle Satellite Cells
EMBO journal, v. 37, (8), April 2018, article number e98239
Wang, Gang; Zhu, Han; Situ, Chenghao; Han, Lifang; Yu, Youqian; Cheung, Tom H.; Liu, Kai; Wu, Zhenguo


Expand All Collapse All


Article 3

A Molecular Switch Regulating Cell Fate Choice between Muscle Progenitor Cells and Brown Adipocytes
Developmental Cell, v. 41, (4), May 2017, p. 382-391.e5
An, Yitai; Wang, Gang; Diao, Yarui; Long, Yanyang; Fu, Xinrong; Weng, Mingxi; Zhou, Liang; Sun, Kun; Cheung, Tom H.; Ip, Nancy Yuk-yu; Sun, Hao; Wang, Huating; Wu, Zhenguo
Anemoside A3 Ameliorates Experimental Autoimmune Encephalomyelitis by Modulating T Helper 17 Cell Response
PLoS ONE, v. 12, (7), July 2017, article number e0182069
Ip, Fanny; Ng, Yupong; Or, Terry Cho Tsun; Sun, Peiran; Fu, Guangmiao; Li, Jessica Y.H.; Ye, Wencai; Cheung, Tom H.; Ip, Nancy Y.Y.
Compact fs Ytterbium Fiber Laser at 1010 nm for Biomedical Applications
Biomedical Optics Express, v. 8, (11), November 2017, article number 300964, p. 4921-4932
Kong, Cihang; Pilger, Christian; Hachmeister, Henning; Wei, Xiaoming; Cheung, Tom H.; Lai, Cora S. W.; Huser, Thomas; Tsia, Kevin. K.; Wong, Kenneth K. Y.


Expand All Collapse All


Article 4

IL-33 Ameliorates Alzheimer’s Disease-like Pathology and Cognitive Decline
Proceedings of the National Academy of Sciences of the United States of America, v. 113, (19), May 2016, p. 2705-2713
Fu, Kit Yu; Hung, Kwok Wang; Yuen, Yat Fai; Zhou, Xiaopu; Mak, Deejay S.Y.; Chan, Chi Wai; Cheung, Tom H.; Zhang, Baorong; Fu, Wing Yu; Liew, Foo Y.; Ip, Nancy Yuk-yu
Intronic Polyadenylation of PDGFRα in Resident Stem Cells Attenuates muscle Fibrosis
Nature, v. 540, (7632), December 2016, p. 276-279
Mueller, Alisa A.; Van Velthoven, Cindy T.; Fukumoto, Kathryn D.; Cheung, Tom H.; Rando, Thomas A.
STAT3 Regulates Self-Renewal of Adult Muscle Satellite Cells during Injury-Induced Muscle Regeneration
Cell Reports, v. 16, (8), 23 August 2016, p. 2102-2115
Zhu, Han; Xiao, Fang; Wang, Gang; Wei, Xiuqing; Jiang, Lei; Chen, Yan; Zhu, Lin; Wang, Haixia; Diao, Yarui; Wang, Huating; Ip, Nancy Y Y; Cheung, Tom H.; Wu, Zhenguo
The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery
Cell, v. 167, (5), November 2016, p. 1145-1149
Stunnenberg, Hendrik G.; The International Human Epigenome Consortium; Cheung, Tom H.; Hirst, Martin

Conference paper 4

IL-33 Ameliorates Alzheimer’s Disease-like Pathology and Cognitive Decline
The 46th Annual Meeting of the Society for Neuroscience, San Diego, USA, 12 - 16 November 2016
Fu, Kit Yu; Hung, Kwok Wang; Yuen, Matthew Ming Fai; Zhou, Xiaopu; Mak, Deejay S.Y.; Chan, I.C.W.; Cheung, Tom H.; Zhang, Baorong; Fu, Wing Yu; Liew, Foo Y.; Ip, Nancy Yuk-yu
IL-33 ameliorates cognitive deficits and amyloid pathology in an Alzheimer’s disease-like mouse model
Molecular & Cellular Neurobiology, Gordon Research Conference, The Hong Kong University of Science and Technology, June, 2016
Fu, Kit Yu; Hung, Kwok Wang; Yuen, M.Y.F.; Zhou, Xiaopu; Mak, D.S.Y.; Chan, I.C.W.; Cheung, Tom; Zhang, B; Fu, Wing Yu; Liew, F.Y.; Ip, Nancy Yuk-yu
IL-33 modulates microglial innate immunity in an Alzheimer’s disease-like mouse model
Molecular & Cellular Neurobiology, Gordon Research Conference, Hong Kong, 12-17 June 2016
Zhou, Xiaopu; Ip, Nancy Yuk-yu; Cheung, Tom; Liew, F.Y.; Chan, I.C.W.; Mak, D.S.Y.; Yuen, M.Y.F.; Hung, Kwok Wang; Fu, Kit Yu; Fu, Wing Yu
IL-33 Modulates the Inflammatory Response in the Brains of Alzheimer’s disease mouse model
The 46th Annual Meeting of the Society for Neuroscience, San Diego, USA, 12-16 November 2016
Fu, Wing Yu; Fu, Kit Yu; Hung, Kwok Wang; Yuen, Matthew Ming Fai; Zhou, Xiaopu; Mak, D.S.Y.; Chan, I.C.W.; Liew, F.Y.; Cheung, Tom H.; Ip, Nancy Yuk-yu


Expand All Collapse All


Article 2

Ex Vivo Expansion and In Vivo Self-Renewal of Human Muscle Stem Cells
Stem Cell Reports, v. 5, (4), October 2015, p. 621-632
Charville, Gregory W.; Cheung, Tom H.; Yoo, Bryan; Santos, Pauline J.; Lee, Gordon K.; Shrager, Joseph B.; Rando, Thomas A.
Isolation of skeletal muscle stem cells by fluorescence-activated cell sorting
Nature Protocols, v. 10, (10), October 2015, p. 1612-1624
Liu, Ling; Cheung, Tom Hiu Tung; Charville, Gregory William; Rando, Thomas A.


Expand All Collapse All


Article 3

All's well that ends well: Alternative polyadenylation and its implications for stem cell biology
Current Opinion in Cell Biology, v. 25, (2), 2013, p. 222-232
Mueller, A.A.; Cheung, Tom Hiu Tung; Rando, T.A.
Chromatin Modifications as determinants of muscle stem cell quiescence and chronological aging
Cell Reports, v. 4, (1), July 2013, p. 189-204
Liu, Ling; Cheung, Tom H.; Charville, Gregory W.; Hurgo, Bernadette Marie Ceniza; Leavitt, Tripp; Shih, Johnathan; Brunet, Anne; Rando, Thomas A.
Molecular regulation of stem cell quiescence
Nature Reviews Molecular Cell Biology, v. 14, (6), June 2013, p. 329-340
Cheung, Tom Hiu Tung; Rando, Thomas A.


Expand All Collapse All


Article 3

Alternative polyadenylation mediates microRNA regulation of muscle stem cell function
Cell stem cell, v. 10, (3), 2012, p. 327-336
Boutet, S.C.; Cheung, Tom Hiu Tung; Quach, N.L.; Liu, L.; Prescott, S.L.; Edalati, A.; Iori, K.; Rando, T.A.
Maintenance of muscle stem-cell quiescence by microRNA-489
Nature, v. 482, (7386), 2012, p. 524-528
Cheung, Tom Hiu Tung; Quach, N.L.; Charville, G.W.; Liu, L.; Park, L.; Edalati, A.; Yoo, B.; Hoang, P.; Rando, T.A.
Notch signaling is necessary to maintain quiescence in adult muscle stem cells
Stem cells, v. 30, (2), 2012, p. 232-242
Bjornson, C.R.R.; Cheung, Tom Hiu Tung; Liu, L.; Tripathi, P.V.; Steeper, K.M.; Rando, T.A.


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Article 1

Remodeling the cardiac transcriptional landscape with diet
Physiological genomics, v. 43, (12), 2011, p. 772-780
Luczak, E.D.; Barthel, K.K.B.; Stauffer, B.L.; Konhilas, J.P.; Cheung, Tom Hiu Tung; Leinwand, L.A.


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Article 2

Identifying pattern-defined regulatory islands in mammalian genomes
Proceedings of the National Academy of Sciences of the United States of America, v.104 , (24), 2007, Jun, p. 10116-10121
Cheung, Tom Hiu Tung; Barthel, K.K.B.; Yin, L.K.; Liu, X.
Systematic Identification of C.?elegans miRISC Proteins, miRNAs, and mRNA Targets by Their Interactions with GW182 Proteins AIN-1 and AIN-2
Molecular cell, v. 28, (4), 2007, p. 598-613
Zhang, L.; Ding, L.; Cheung, Tom Hiu Tung; Dong, M.Q.; Chen, J.; Sewell, A.K.; Liu, X.; Yates III, J.R.; Han, M.


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Article 2

Global gene expression analysis of ERK5 and ERK1/2 signaling reveals a role for HIF-1 in ERK5-mediated responses
Journal of Biological Chemistry, v. 281, (30), 2006, p. 20993-21003
Schweppe, RE; Cheung, Tom Hiu Tung; Ahn, NG
Unraveling transcriptional control and cis-regulatory codes using the software suite GeneACT
Genome Biology, v. 7, (10), 2006
Cheung, Tom Hiu Tung; Kwan, YL; Hamady, M.; Liu, X.


Expand All Collapse All


Article 3

A method of mapping protein sumoylation sites by mass spectrometry using a modified small ubiquitin-like modifier 1 (SUMO-1) and a computational program
Molecular & cellular proteomics, v. 4, (10), October 2005, p. 1626-1636
Knuesel, M.; Cheung, Tom H.; Hamady, M.; Barthel, KKB; Liu, XD
Does protein structure influence trypsin miscleavage?
IEEE Engineering in Medicine and Biology Magazine, v. 24, (3), 2005, p. 58-66
Hamady, M.; Cheung, Tom Hiu Tung; Tufo, H.; Knight, R.
Key challenges in proteomics and proteoinformatics
IEEE Engineering in Medicine and Biology Magazine, v. 24, (3), 2005, p. 34-40
Hamady, M.; Cheung, Tom Hiu Tung; Resing, K.; Cios, K.J.; Knight, R.


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Article 2

Control of cell cycle-dependent degradation of c-Ski proto-oncoprotein by Cdc34
Oncogene, v. 23, (33), 2004, p. 5643-5653
Macdonald, M.; Wan, Y.; Wang, W.; Roberts, E.; Cheung, Tom Hiu Tung; Erickson, R.; Knuesel, MT; Liu, X.
Improving reproducibility and sensitivity in identifying human proteins by shotgun proteomics
Analytical chemistry, v. 76, (13), July 2004, p. 3556-3568
Resing, KA; Meyer-Arendt, K.; Mendoza, AM; Aveline-Wolf, LD; Jonscher, KR; Pierce, KG; Old, WM; Cheung, Tom Hiu Tung; Russell, S.; Wattawa, JL; Goehle, GR; Knight, RD; Ahn, NG


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2016 8

IL-33 Ameliorates Alzheimer’s Disease-like Pathology and Cognitive Decline
Proceedings of the National Academy of Sciences of the United States of America, v. 113, (19), May 2016, p. 2705-2713
Fu, Kit Yu; Hung, Kwok Wang; Yuen, Yat Fai; Zhou, Xiaopu; Mak, Deejay S.Y.; Chan, Chi Wai; Cheung, Tom H.; Zhang, Baorong; Fu, Wing Yu; Liew, Foo Y.; Ip, Nancy Yuk-yu Article
Intronic Polyadenylation of PDGFRα in Resident Stem Cells Attenuates muscle Fibrosis
Nature, v. 540, (7632), December 2016, p. 276-279
Mueller, Alisa A.; Van Velthoven, Cindy T.; Fukumoto, Kathryn D.; Cheung, Tom H.; Rando, Thomas A. Article
STAT3 Regulates Self-Renewal of Adult Muscle Satellite Cells during Injury-Induced Muscle Regeneration
Cell Reports, v. 16, (8), 23 August 2016, p. 2102-2115
Zhu, Han; Xiao, Fang; Wang, Gang; Wei, Xiuqing; Jiang, Lei; Chen, Yan; Zhu, Lin; Wang, Haixia; Diao, Yarui; Wang, Huating; Ip, Nancy Y Y; Cheung, Tom H.; Wu, Zhenguo Article
The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery
Cell, v. 167, (5), November 2016, p. 1145-1149
Stunnenberg, Hendrik G.; The International Human Epigenome Consortium; Cheung, Tom H.; Hirst, Martin Article
IL-33 Ameliorates Alzheimer’s Disease-like Pathology and Cognitive Decline
The 46th Annual Meeting of the Society for Neuroscience, San Diego, USA, 12 - 16 November 2016
Fu, Kit Yu; Hung, Kwok Wang; Yuen, Matthew Ming Fai; Zhou, Xiaopu; Mak, Deejay S.Y.; Chan, I.C.W.; Cheung, Tom H.; Zhang, Baorong; Fu, Wing Yu; Liew, Foo Y.; Ip, Nancy Yuk-yu Conference paper
IL-33 ameliorates cognitive deficits and amyloid pathology in an Alzheimer’s disease-like mouse model
Molecular & Cellular Neurobiology, Gordon Research Conference, The Hong Kong University of Science and Technology, June, 2016
Fu, Kit Yu; Hung, Kwok Wang; Yuen, M.Y.F.; Zhou, Xiaopu; Mak, D.S.Y.; Chan, I.C.W.; Cheung, Tom; Zhang, B; Fu, Wing Yu; Liew, F.Y.; Ip, Nancy Yuk-yu Conference paper
IL-33 modulates microglial innate immunity in an Alzheimer’s disease-like mouse model
Molecular & Cellular Neurobiology, Gordon Research Conference, Hong Kong, 12-17 June 2016
Zhou, Xiaopu; Ip, Nancy Yuk-yu; Cheung, Tom; Liew, F.Y.; Chan, I.C.W.; Mak, D.S.Y.; Yuen, M.Y.F.; Hung, Kwok Wang; Fu, Kit Yu; Fu, Wing Yu Conference paper
IL-33 Modulates the Inflammatory Response in the Brains of Alzheimer’s disease mouse model
The 46th Annual Meeting of the Society for Neuroscience, San Diego, USA, 12-16 November 2016
Fu, Wing Yu; Fu, Kit Yu; Hung, Kwok Wang; Yuen, Matthew Ming Fai; Zhou, Xiaopu; Mak, D.S.Y.; Chan, I.C.W.; Liew, F.Y.; Cheung, Tom H.; Ip, Nancy Yuk-yu Conference paper

2015 2

Ex Vivo Expansion and In Vivo Self-Renewal of Human Muscle Stem Cells
Stem Cell Reports, v. 5, (4), October 2015, p. 621-632
Charville, Gregory W.; Cheung, Tom H.; Yoo, Bryan; Santos, Pauline J.; Lee, Gordon K.; Shrager, Joseph B.; Rando, Thomas A. Article
Isolation of skeletal muscle stem cells by fluorescence-activated cell sorting
Nature Protocols, v. 10, (10), October 2015, p. 1612-1624
Liu, Ling; Cheung, Tom Hiu Tung; Charville, Gregory William; Rando, Thomas A. Article

2013 3

All's well that ends well: Alternative polyadenylation and its implications for stem cell biology
Current Opinion in Cell Biology, v. 25, (2), 2013, p. 222-232
Mueller, A.A.; Cheung, Tom Hiu Tung; Rando, T.A. Article
Chromatin Modifications as determinants of muscle stem cell quiescence and chronological aging
Cell Reports, v. 4, (1), July 2013, p. 189-204
Liu, Ling; Cheung, Tom H.; Charville, Gregory W.; Hurgo, Bernadette Marie Ceniza; Leavitt, Tripp; Shih, Johnathan; Brunet, Anne; Rando, Thomas A. Article
Molecular regulation of stem cell quiescence
Nature Reviews Molecular Cell Biology, v. 14, (6), June 2013, p. 329-340
Cheung, Tom Hiu Tung; Rando, Thomas A. Article

2012 3

Alternative polyadenylation mediates microRNA regulation of muscle stem cell function
Cell stem cell, v. 10, (3), 2012, p. 327-336
Boutet, S.C.; Cheung, Tom Hiu Tung; Quach, N.L.; Liu, L.; Prescott, S.L.; Edalati, A.; Iori, K.; Rando, T.A. Article
Maintenance of muscle stem-cell quiescence by microRNA-489
Nature, v. 482, (7386), 2012, p. 524-528
Cheung, Tom Hiu Tung; Quach, N.L.; Charville, G.W.; Liu, L.; Park, L.; Edalati, A.; Yoo, B.; Hoang, P.; Rando, T.A. Article
Notch signaling is necessary to maintain quiescence in adult muscle stem cells
Stem cells, v. 30, (2), 2012, p. 232-242
Bjornson, C.R.R.; Cheung, Tom Hiu Tung; Liu, L.; Tripathi, P.V.; Steeper, K.M.; Rando, T.A. Article

2011 1

Remodeling the cardiac transcriptional landscape with diet
Physiological genomics, v. 43, (12), 2011, p. 772-780
Luczak, E.D.; Barthel, K.K.B.; Stauffer, B.L.; Konhilas, J.P.; Cheung, Tom Hiu Tung; Leinwand, L.A. Article

2007 2

Identifying pattern-defined regulatory islands in mammalian genomes
Proceedings of the National Academy of Sciences of the United States of America, v.104 , (24), 2007, Jun, p. 10116-10121
Cheung, Tom Hiu Tung; Barthel, K.K.B.; Yin, L.K.; Liu, X. Article
Systematic Identification of C.?elegans miRISC Proteins, miRNAs, and mRNA Targets by Their Interactions with GW182 Proteins AIN-1 and AIN-2
Molecular cell, v. 28, (4), 2007, p. 598-613
Zhang, L.; Ding, L.; Cheung, Tom Hiu Tung; Dong, M.Q.; Chen, J.; Sewell, A.K.; Liu, X.; Yates III, J.R.; Han, M. Article

2006 2

Global gene expression analysis of ERK5 and ERK1/2 signaling reveals a role for HIF-1 in ERK5-mediated responses
Journal of Biological Chemistry, v. 281, (30), 2006, p. 20993-21003
Schweppe, RE; Cheung, Tom Hiu Tung; Ahn, NG Article
Unraveling transcriptional control and cis-regulatory codes using the software suite GeneACT
Genome Biology, v. 7, (10), 2006
Cheung, Tom Hiu Tung; Kwan, YL; Hamady, M.; Liu, X. Article

2005 3

A method of mapping protein sumoylation sites by mass spectrometry using a modified small ubiquitin-like modifier 1 (SUMO-1) and a computational program
Molecular & cellular proteomics, v. 4, (10), October 2005, p. 1626-1636
Knuesel, M.; Cheung, Tom H.; Hamady, M.; Barthel, KKB; Liu, XD Article
Does protein structure influence trypsin miscleavage?
IEEE Engineering in Medicine and Biology Magazine, v. 24, (3), 2005, p. 58-66
Hamady, M.; Cheung, Tom Hiu Tung; Tufo, H.; Knight, R. Article
Key challenges in proteomics and proteoinformatics
IEEE Engineering in Medicine and Biology Magazine, v. 24, (3), 2005, p. 34-40
Hamady, M.; Cheung, Tom Hiu Tung; Resing, K.; Cios, K.J.; Knight, R. Article

2004 2

Control of cell cycle-dependent degradation of c-Ski proto-oncoprotein by Cdc34
Oncogene, v. 23, (33), 2004, p. 5643-5653
Macdonald, M.; Wan, Y.; Wang, W.; Roberts, E.; Cheung, Tom Hiu Tung; Erickson, R.; Knuesel, MT; Liu, X. Article
Improving reproducibility and sensitivity in identifying human proteins by shotgun proteomics
Analytical chemistry, v. 76, (13), July 2004, p. 3556-3568
Resing, KA; Meyer-Arendt, K.; Mendoza, AM; Aveline-Wolf, LD; Jonscher, KR; Pierce, KG; Old, WM; Cheung, Tom Hiu Tung; Russell, S.; Wattawa, JL; Goehle, GR; Knight, RD; Ahn, NG Article


No Publications






Teaching Assignment

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2021-22 Winter 0 2021-22 Fall 5 2020-21 Summer 1 2020-21 Spring 9 2020-21 Winter 0 2020-21 Fall 6

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LIFS4370 Human Genetics and Personalized Medicine
LIFS5070 Workshops in Biosciences
SCIE3500 IRE Research Project I
SCIE4500 IRE Research Project II
UROP1100E Undergraduate Research Opportunities Series 1


LIFS3520 Junior Research Project II


LIFS3520 Junior Research Project II
LIFS3580 Bioinformatics
LIFS4963 Biotechnology Capstone Project
LIFS4981 Biochemistry and Cell Biology Project Research II
LIFS4983 Biotechnology Project Research II
LIFS6116D Current Topics in Genomics and Bioinformatics
LIFS6800 Frontiers in Nucleic Acid Research
SCIE2500 Guided Study on Research II
SCIE3500 IRE Research Project I


LIFS4370 Human Genetics and Personalized Medicine
LIFS4961 Biochemistry and Cell Biology Capstone Project
LIFS4963 Biotechnology Capstone Project
LIFS4971 Biochemistry and Cell Biology Project Research I
LIFS4973 Biotechnology Project Research I
LIFS5070 Workshops in Biosciences


No Teaching Assignments


No Teaching Assignments






Research Postgraduate (RPG) Supervision From January 2019 to December 2022 (As of 30 January 2022)

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All Supervisions Current RPGs Graduated RPGs

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Current RPGs

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Doctor of Philosophy KUNG, Wai Hing
Life Science( 2021 - )

HU, Shenyuan
Life Science( 2020 - )

LUAN, Shaoyuan
Life Science( 2018 - )

HE, Jiawei
Life Science( 2017 - )

LAM, Sheung Wai
Life Science( 2017 - )

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Master of Philosophy NGAN, Lok Pui
Life Science( 2020 - )

PREUSCH, Christopher Brandon
Life Science( 2019 - )

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Graduated RPGs

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Doctor of Philosophy DONG, Anqi
Life Science( Completed in 2021 )

LIN, Kangning
Life Science( Completed in 2021 )

YI, Ran
Life Science( Completed in 2021 )

ZENG, Wenshu
Life Science( Completed in 2021 )

YUE, Lu
Life Science( Completed in 2020 )

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Master of Philosophy HU, Shenyuan
Life Science( Completed in 2020 )









ProjectsFrom January 2020 to December 2022

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All Projects 19 Leading Projects 7 Participating Projects 12

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Stem cell-niche interactions in tissue maintenance and engineering


干细胞与微环境互作在组织维持和组织工程中的应用 Participating


RGC - Theme-based Research Scheme


Project Team (HKUST)
XIE Ting (Lead)
CHEUNG Tom
GUO Yusong
LEUNG Danny Chi Yeu
LIU Kai
MAK Ho Yi
SUN Fei
WEN Zilong
WU Angela Ruohao
WU Zhenguo
YAN Yan


2022 -




Development Of Therapeutic Molecules For Alzheimer’s Disease Based On High-performance Plasma Proteome Profiling


基於高效血浆蛋白质组学分析的阿尔茨海默症分子干预策略研究 Participating


Fong's Family Foundation, Innovation and Technology Fund, Morningside Life Science Limited


Project Team (HKUST)
IP Nancy Yuk-Yu (Lead)
CHEUNG Tom
FU Amy Kit Yu
LIU Kai


2022 -




Post-transcriptional regulation of muscle stem cell early activation by Rbfox2


Rbfox2对肌肉干细胞早期活化的转录後调控 Leading


RGC - General Research Fund


Project Team (HKUST)
CHEUNG Tom (Lead)


2021 -




The Center for Neurodegenerative Diseases


N/A Participating


Innovation and Technology Fund


Project Team (HKUST)
IP Nancy Yuk-Yu (Lead)
CHEUNG Tom
FU Amy Kit Yu
LEUNG Danny Chi Yeu
LIU Kai
WANG Jiguang
WONG Yung Hou
WU Zhenguo


2020 -




Investigating the Cellular Dynamics in Skeletal Muscles for Early Detection of Sarcopenia during Aging Leading


Health and Medical Research Fund


Project Team (HKUST)
CHEUNG Tom (Lead)


2020 -




Molecular regulation of muscle stem cell mitochondrial functions by CPEB4


CPEB4对肌肉干细胞线粒体功能的分子调控 Leading


RGC - General Research Fund


Project Team (HKUST)
CHEUNG Tom (Lead)


2020 -




Molecular regulation of quiescence and early activation in muscle stem cells


骨骼肌干细胞静息态及早期活化的分子调控 Participating


RGC - Collaborative Research Fund


Project Team (HKUST)
WU Zhenguo (Lead)
CHEUNG Tom
LEUNG Danny Chi Yeu


2020 -




The Role of IL-33 in Synaptic Dysfunctions and Pathogenesis of Alzheimer's Disease


白介素-33在阿兹海默氏症突触功能失调及发病过程中的作用 Participating


RGC - Collaborative Research Fund


Project Team (HKUST)
IP Nancy Yuk-Yu (Lead)
CHEUNG Tom
FU Amy Kit Yu
WU Zhenguo
XIA Jun


2020 -




Modelling and application of risk assessment based on molecular biomakers


基于生物标志物的风险评估模型建立和应用 Leading


Shenzhen Science and Technology Innovation Committee


Project Team (HKUST)
CHEUNG Tom (Lead)
ZHOU Fred Xiaopu


2020 -




A Stem Cell Approach to Dissect the Molecular Basis of Neurodegenerative Diseases


以干细胞方法解析神经退行性疾病的分子基础 Participating


RGC - Theme-based Research Scheme


Project Team (HKUST)
IP Nancy Yuk-Yu (Lead)
CHEUNG Tom
CHUNG Kenny K
FU Amy Kit Yu
QI Robert Zhong
QU Jianan
TSIM Karl Wah Keung
WEN Zilong
WONG Yung Hou
WU Zhenguo
XIA Jun


2019 -




Post-transcriptional regulation of muscle stem cell early activation by CPEB1?


CPEB1介导的转录後调控机制在骨骼肌干细胞早期激活过程的作用机理研究 Leading


RGC - General Research Fund


Project Team (HKUST)
CHEUNG Tom (Lead)


2019 -




Study of a novel population of mammary stem cells arise during pregnancy


研究在孕期乳腺产生的一群新的干细胞 Leading


National Natural Science Foundation of China / Research Grants Council Joint Research Scheme


Project Team (HKUST)
CHEUNG Tom (Lead)


2019 -




Comprehensive Analysis Of Molecular, Structural And Functional Biomarkers For Alzheimer's Disease In The Chinese Population


中国人群阿尔茨海默症相关生物标志物的分子、结构和功能综合分析 Participating


Innovation and Technology Fund


Project Team (HKUST)
IP Nancy Yuk-Yu (Lead)
CHEUNG Tom
FU Amy Kit Yu


2019 -




Identification of epigenetic biomarkers for Alzheimer's disease in blood using epigenome-wide analysis


利用表观基因组关联研究分析监定血液中阿尔茨海默病的表观遗传生物标志物 Participating


Bio-Gene Technology Limited, Fong's Family Foundation, Innovation and Technology Fund, Oracle Link Technology Ltd.


Project Team (HKUST)
IP Nancy Yuk-Yu (Lead)
CHEUNG Tom
FU Amy Kit Yu


2019 -




Multi-dimensional analysis of biomarkers for Alzheimer's disease in the Chinese population


中国人群阿尔茨海默症多维度生物标志物综合研究 Participating


Ministry of Science and Technology of the People's Republic of China


Project Team (HKUST)
CHEUNG Tom
IP Nancy Yuk-Yu
ZHOU Fred Xiaopu


2019 -




The Research on diagnosis and treatment of Alzheimer's disease


阿尔茨海默症的诊治方法研究 Participating


Department of Science and Technology of Guangdong Province


Project Team (HKUST)
IP Nancy Yuk-Yu (Lead)
CHEUNG Tom
FU Amy Kit Yu
LIU Kai
WONG Yung Hou
WU Zhenguo
ZHOU Fred Xiaopu


2018 -




Cellular mechanisms of synaptic functions and plasticity in health and neurodegenerative diseases


健康及神经退行性病变过程中突触功能和可塑性调控的细胞机制 Participating


RGC - Areas of Excellence Scheme


Project Team (HKUST)
IP Nancy Yuk-Yu (Lead)
CHEUNG Tom
FU Amy Kit Yu
LIU Kai
WONG Yung Hou
WU Zhenguo
XIA Jun


2017 -




A groundbreaking research for the development of treatments for Alzheimer's Disease ("AD") focusing on the Chinese population Participating


Lee Hysan Foundation


Project Team (HKUST)
IP Nancy Yuk-Yu (Lead)
CHEUNG Tom
FU Amy Kit Yu


2016 -




Molecular regulation of muscle stem cell ageing Leading


Croucher Foundation


Project Team (HKUST)
CHEUNG Tom (Lead)


2015 - 2021