Faculty Staff
Dr Pelekos, George

MUDr, MSc (Masaryk); MClinDent (UCL), PhD, MFDSRCS





General Information
Title

Clinical Assistant Professor in Periodontology


Division

Periodontology & Implant Dentistry


E-mail

george74@hku.hk
>


Phone Number

2859 0343


Research profile

HKU Scholars Hub
>
Scopus
>
ORCID
>


Areas of Research Expertise

Peri-implant disease
Agressive periodontitis
Periodontal regeneration




Category
Publications Knowledge Exchange Professional Societies Grants Invited Lectures and Keynote Speeches HKU Committee Appointments


Advanced Sorting
Publications
Article
Ning W, Acharya A, Sun Z, Ogbuehi AC, Li C, Hua S, Ou Q, Zeng M, Liu X, Deng Y, Haak R, Ziebolz D, Schmalz G, Pelekos G, Wang Y, Hu X. Deep Learning Reveals Key Immunosuppression Genes and Distinct Immunotypes in Periodontitis, Frontiers in Genetics 2021; 12: article no. 648329-article no. 648329 doi:10.3389/fgene.2021.648329
Ho DKL, Wong JHL, Pelekos G, Deng K, Tonetti MS. Prevalence and morphological characteristics of disto-lingual roots in mandibular first molars: a cone beam CT study with diagnostic and therapeutic implications, Clinical Oral Investigations 2021; 25(6): 4023-4030 doi:10.1007/s00784-020-03733-3
Nibali L, Sultan D, Arena C, Pelekos G, Lin GH, Tonetti M. Periodontal infrabony defects: Systematic review of healing by defect morphology following regenerative surgery, Journal of Clinical Periodontology 2021; 48(1): 100-113 doi:10.1111/jcpe.13381
FOK MR, Pelekos G, Tonetti MS. Feasibility and needs for simultaneous or staged bone augmentation to place prosthetically guided dental implants after extraction or exfoliation of first molars due to severe periodontitis, Journal of Clinical Periodontology 2020; 47(10): 1237-1247 doi:10.1111/jcpe.13344
Pelekos G, Acharya A, Eiji N, Hong G, Leung WK, McGrath C. Effects of adjunctive probiotic L. reuteri lozenges on S/RSD outcomes at molar sites with deep pockets, Journal of Clinical Periodontology 2020; 47(9): 1098-1107 doi:10.1111/jcpe.13329
ZHAO D, Khawaja AT, Jin L, Chan KW, Tonetti M, Tang SCW, Pelekos G. Effect of non-surgical periodontal therapy on renal function in chronic kidney disease patients with periodontitis: a systematic review and meta-analysis of interventional studies, Clinical Oral Investigations 2020; 24: 1607-1618 doi:10.1007/s00784-019-03066-w
WANG Y, Liu HN, Zhen Z, Pelekos G, Wu MZ, Chen Y, Tonetti M, Tse HF, Yiu KH, Jin L. A randomized controlled trial of the effects of non‐surgical periodontal therapy on cardiac function assessed by echocardiography in type 2 diabetic patients, Journal of Clinical Periodontology 2020; 47(6): 726-736 doi:10.1111/jcpe.13291
HO SN, Acharya A, Sidharthan S, Li KY, Leung WK, McGrath C, Pelekos G. A Systematic Review and Meta-analysis of Clinical, Immunological, and Microbiological Shift in Periodontitis After Nonsurgical Periodontal Therapy With Adjunctive Use of Probiotics, Journal of Evidence Based Dental Practice 2020; 20(1): article no. 101397-article no. 101397 doi:10.1016/j.jebdp.2020.101397
Gupta B, Acharya A, Singh S, Brazolli S, Ghorab M, Malik S, Pelekos G, Rossouw PE. Evaluation of jawbone morphology and bone density indices in panoramic radiographs of selective serotonin reuptake inhibitor users: a preliminary study, Dentomaxillofacial Radiology 2019; 48(1): article no. **-article no. ** doi:10.1259/dmfr.**
Acharya A, Li S, Liu X, Pelekos G, Ziebolz D, Mattheos N. Biological links in Periodontitis and Rheumatoid arthritis: discovery via text-mining PubMed abstracts, Journal of Periodontal Research 2019; 54(4): 318-328 doi:10.1111/jre.12632
Chan YH, Pelekos G, Ho KL, Cortellini P, Tonetti M. The depth of the implant mucosal tunnel modifies the development and resolution of experimental peri-implant mucositis: A case-control study, Journal of Clinical Periodontology 2019; 46: 248-255 doi:10.1111/jcpe.13066
ZHAO D, Zhen Z, Pelekos G, Yiu KH, Jin L. Periodontal disease increases the risk for onset of systemic comorbidities in dental hospital attendees: An 18-year retrospective cohort study, Journal of Periodontology 2019; 90: 225-233 doi:10.1002/JPER.18-0224
Jagannathan N, Acharya A, Ong F, Li KY, Nibali L, Pelekos G. Disease severity, debridement approach and timing of drug modify outcomes of adjunctive azithromycin in non-surgical management of chronic periodontitis: a multivariate meta-analysis, BMC Oral Health 2019; 19: 65-65 doi:10.1186/s12903-019-0754-0
Pelekos G, Lu JZ, Ho DKL, Graziani F, Cairo F, Cortellini P, Tonetti MS. Aesthetic assessment after root coverage of multiple adjacent recessions with coronally advanced flap with adjunctive collagen matrix or connective tissue graft: Randomized clinical trial, Journal of Clinical Periodontology 2019; 46(5): 564-571 doi:10.1111/jcpe.13103
Wang Y, Zhen Z, Liu HN, Lai I, Pelekos G, Tse HF, Yiu KH, Jin L. Periodontitis links to exacerbation of myocardial dysfunction in subjects with type 2 diabetes, Journal of Periodontal Research 2019; 54(4): 339-348 doi:10.1111/jre.12634
Pelekos G, HO SN, Acharya A, Leung WK, McGrath C. A double‐blind, paralleled‐arm, placebo‐controlled and randomized clinical trial of the effectiveness of probiotics as an adjunct in periodontal care, Journal of Clinical Periodontology 2019; 46(12): 1217-1227 doi:10.1111/jcpe.13191
Pelekos G, Tse JMN, Ho D, Tonetti MS. Defect morphology, bone thickness, exposure settings and examiner experience affect the diagnostic accuracy of standardized digital periapical radiographic images but not of cone beam computed tomography in the detection of peri‐implant osseous defects: An in vitro study, Journal of Clinical Periodontology 2019; 46(12): 1294-1302 doi:10.1111/jcpe.13200
Kaiser F, Donos N, Henderson B, Alagarswamy R, Pelekos G, Boniface D, Nibali L. Association between circulating levels of heat-shock protein 27 and aggressive periodontitis, Cell Stress and Chaperones 2018; 23: 847-856 doi:10.1007/s12192-018-0891-4
ZHAO D, Khawaja AT, Jin L, Li KY, Tonetti M, Pelekos G. The directional and non-directional associations of periodontitis with chronic kidney disease: A systematic review and meta-analysis of observational studies, Journal of Periodontal Research 2018; 53(5): 682-704 doi:10.1111/jre.12565
Pelekos G, Acharya A, Tonetti M, Bornstein MM. Diagnostic performance of cone beam computed tomography in assessing peri-implant bone loss: A systematic review, Clinical Oral Implants Research 2018; 29(5): 443-464 doi:10.1111/clr.13143
WANG Y, Liu HN, Zhen Z, Yiu KH, Tse HF, Pelekos G, Tonetti M, Jin L. Periodontal treatment modulates gene expression of endothelial progenitor cells in diabetic patients, Journal of Clinical Periodontology 2017; 44: 1253-1263 doi:10.1111/jcpe.12806
Liu F, Pelekos G, Jin LJ. The gingival biotype in a cohort of Chinese subjects with and without history of periodontal disease, Journal of Periodontal Research 2017; 52(6): 1004-1010 doi:10.1111/jre.12471
Gupta B, ACHARYA A, Pelekos G, Gopalakrishnan D, Kolokythas A. Selective serotonin reuptake inhibitors and dental implant failure-A significant concern in elders?, Gerodontology 2017; 34(4): 505-507 doi:10.1111/ger.12287
Pelekos G, Mardas N. Natural teeth or implants? Informing the decision-making process, Implant Practice US 2015; 8(3): 38-40
Nibali L, Rizzo M, Li Volti G, D'Aiuto F, Giglio RV, Barbagallo I, Pelekos G, Donos L. Lipid subclasses profiles and oxidative stress in aggressive periodontitis before and after treatment, Journal of Periodontal Research 2015; 50: 890-896 doi:10.1111/jre.12283
Nibali L, Pelekos G, Onabolu O, Donos N. Effect and timing of non-surgical treatment prior to periodontal regeneration: a systematic review, Clinical Oral Investigations 2015; 19: 1755-1761 doi:10.1007/s00784-015-1493-5
Pelekos G. Non-surgical treatment in periodontal treatment in modern periodontoogy. Is periodontal surgery still important?, Hong Kong Dental Association Newsletter 2015; 12-15
Nibali L, Pelekos G, D'Aiuto F, Chaudhary N, Habeeb R, Ready D, Parkar M, Donos N. Influence of IL-6 haplotypes on clinical and inflammatory response in aggressive periodontitis, Clinical Oral Investigations 2013; 17(4): 1235-1242 doi:10.1007/s00784-012-0804-3
Conference Paper
Zhao D, Yiu KH, Wu M, Yu SY, Pelekos G, Jin L. Is severe periodontitis a pre-indicator of abnormal systemic conditions?, Journal of Dental Research (Spec Issue) 2019; 98(Spec Iss A): abstract no. 0361-abstract no. 0361
Wang Y, Liu HN, Zhen Z, Yiu KH, Tse HF, Zhang C, Pelekos G, Jin L. Periodontal treatment increases circulating EPC counts in patients with T2DM, Journal of Dental Research (Spec Issue) 2018; 97(Spec Iss B): no. 1114-no. 1114
Wang Y, Zhen Z, Liu HN, Lai IA, Pelekos G, Tse HF, Yiu KH, Jin L. A case‐control study on periodontitis and left ventricular function in patients with diabetes, Journal of Clinical Periodontology 2018; 45(S19): 98 Abstract no. PD156-98 Abstract no. PD156 doi:10.1111/jcpe.160_12914
Zhao D, Yiu KH, Zhen Z, Pelekos G, Tonetti M, Jin L. Oral/periodontal conditions are closely associated with general health status and comorbidity profiles, Journal of Clinical Periodontology 2018; 45(S19): 87 Abstract no. PD128-87 Abstract no. PD128 doi:10.1111/jcpe.130_12914
Zhao D, Luo W, Pelekos G, Jin L. Kidney infection pathogen/P. gingivalis lipopolysaccharides modulate pro-inflammatory response in hRPTEpiCs, Journal of Dental Research (Spec Issue) 2018; 97(Spec Iss B): abstract no. 3492-abstract no. 3492
Zhao D, Yiu KH, Zhen Z, Pelekos G, Jin L. Deterioration of periodontal conditions reflects individual susceptibility to systemic comorbidities?, Journal of Dental Research 2017; 96(Spec B): 191-191
Wang Y, Liu HN, Zhen Z, Yiu KH, Tse HF, Pelekos G, Jin L. Decreased CPC/EPC counts in type 2 diabetes patients with periodontitis, Journal of Dental Research 2017; 96(Spec Iss B): 153-153
Wang Y, Liu HN, Zhen Z, Yiu KH, Pelekos G, Tse HF, Jin L. Periodontal treatment affects gene expression of EPCs in DM patients, Journal of Dental Research (Spec Issue) 2017; 96(Spec Iss A): abstract no. 2195-abstract no. 2195
Liu F, Pelekos G, Jin L. The gingival biotype in a cohort of Chinese subjects with and without history of periodontal disease, Journal of Dental Research (Spec Issue) 2017; 96(Spec Iss A): no. 3480-no. 3480
Zhao D, Yiu KH, Zhen Z, Pelekos G, Jin L. Periodontitis is linked to noncommunicable diseases among dental hospital attendees, Journal of Dental Research (Spec Issue) 2017; 96(Spec Iss A): abstract no. 0963-abstract no. 0963
Nibali L, Kaiser F, Alagarswami R, Henderson B, Pelekos G, Donos N. Differential circulating levels of HSP-27 in chronic and aggressive periodontitis, Journal of Dental Research (Spec Issue) 2017; 96(Spec Iss A): no. 1748-no. 1748
Wang Y, Liu HHL, Zhen Z, Yiu KH, Tse HF, Pelekos G, Jin L. Periodontitis links with EPC counts in patients with T2 diabetes, Journal of Dental Research 2016; 95(Spec. Iss. B)
Nibali L, Rizzo M, Livolti GL, D'Aiuto F, Pelekos G, Donos N. Lipid subclasses profiles and oxidative stress in aggressive periodontitis before and after treatment, Journal of Dental Research Meeting Abstracts 2015; 94(Spec. Iss. A)
Eng HL, Pelekos G. Effects of pregnancy on aggressive periodontitis disease progression, Journal of Dental Research 2015; 94(Spec Iss B (SEA Division))
Cheng CK, Jin LJ, Pelekos G. Halitosis and oral/periodontal conditions in Hong Kong adults, Journal of Dental Research 2015; 94(Spec Iss B (SEA Division))
Chang JWW, Pelekos G, Pow EHN. Clinical challenges and solutions, Hong Kong International Dental Expo and Symposium, 2015 2015;
Pelekos G, Nibali L, Donos N, Onabolu L. Non-surgical treatment in periodontal regeneration studies: a systematic review, Journal of Dental Research 2014; 93(Spec. Iss. C)

Knowledge Exchange
29 August 2020: Pelekos Georgios. The importance of periodontal health.
14 July 2019: Pelekos Georgios. Service Trip /Dental Volunteering Cambodia 2019 .
03 June 2019: Bornstein Michael Marc, Flemmig Thomas Frank, Watt Rory Munro, Pelekos Georgios, McGrath Colman Patrick Joseph, Mariano Sanz, Nairn Wilson, Margaret Wilson, Sa?o Ivanovski, Jennifer Go, Bo Chen, Lisa Heitz-Mayfield, Niklaus P. Lang, Ki-Tae Koo, Atsushi Saito, Samantha Li. Osteology Research Academy Hong Kong 3 – 6 June 2019.
10 November 2017: Pelekos Georgios. Perimplantitis no panacea here.
03 March 2017: Pelekos Georgios. oSouth China Dental exhibition conference in Guangzhou .
20 January 2017: Pelekos Georgios. Promotion of studying dentistry in HKU/Interview of overseas applicants for HKU (Malaysia KL/Singapore).
08 August 2016: Pelekos Georgios. Cultural and Dental Exchange visit (HKU/SYSU(.
12 May 2016: Pelekos Georgios. Promotion of studying in HKU/Dentistry.
23 April 2016: Pelekos Georgios. Interview by Xinhua TV about ranking No1 globally by HKU in dentistry.
12 March 2016: Pelekos Georgios. Health and aging HKMA sysmposium.
07 August 2015: Pelekos Georgios. : The periodontal curriculum on undergraduate level in HKU.

Professional Societies
2018-current: member. RCPSC(Glg).
2014-current: member. HKDA.
2014 -current: member. SPID HK.
2012 -present: member. IADR.
2008 until current: Member. ITI international team for Implantology.
2005-current: Specialist Reg.. GDC.

Grants
Project Title: Coronectomy versus total removal of lower third molars in the periodontal attachment and bone regeneration of adjacent second molars: A randomized clinical trial
Grant Type: General Research Fund (GRF)
Funding Year: 2020
Amount: HKD944454
Principal Investigator: Dr Leung, Mike Yiu Yan
Co-investigator(s): Dr Pelekos Georgios, Professor Wong May Chun Mei, Professor Tonetti Maurizio, Dr Yeung Wai Kan Andy
Project Title: Self-detection and professional screening strategies for early detection of periodontitis: diagnostic accuracy of bleeding on brushing, salivary aMMP-8 and CDC/AAP screening
Grant Type: Health and Medical Research Fund - Full Grant
Funding Year: 2019
Amount: HKD880112
Principal Investigator: Professor Jin, Lijian
Co-investigator(s): Dr Ho King Lun, Professor Tonetti Maurizio, Dr Pelekos Georgios
Project Title: Are periodontitis and masticatory dysfunction associated with the rate of progression of chronic kidney disease in patients with type 2 diabetes?
Grant Type: Health and Medical Research Fund - Full Grant
Funding Year: 2019
Amount: HKD187250
Principal Investigator: Dr Pelekos, Georgios
Co-investigator(s): Professor Tonetti Maurizio, Dr Chan Kam Wa, Professor Tang Sydney Chi Wai
Project Title: Randomized non-inferiority controlled clinical trial comparing periodontal endoscopic surgery and open flap debridement in the management of intra-bony defects: clinical and patient reported outcome measures
Grant Type: Health and Medical Research Fund - Full Grant
Funding Year: 2018
Amount: HKD187586
Principal Investigator: Dr Ho, King Lun
Co-investigator(s): Dr Pelekos Georgios, Professor Tonetti Maurizio

Invited Lectures and Keynote Speeches
06 February 2021: Management of extraction sockets in future implant sites. ITI study club Greece.
23 February 2017: Periimplantitis ...Times for a new disease . oNepalese Society of Periodontology -Oration lecture .
17 June 2016: Critical assessment and comprehensive care are fundamental for preventing Peri-implantitis”. oHong Kong Asian Pacific Dental Conference.
31 March 2016: Teeth vs Implants Decision Making . Sendai Tohoku University .
15 March 2016: “Principles of guided bone regeneration “). Greek Society for Oral Surgery .
05 November 2015: ‘The importance of soft tissues around implants). Botiss Seminars Hong Kong.
23 May 2015: Different therapeutic approaches in periodontology. Fujian Stomatology University China .
16 March 2015: Aggressive Periodontitis. DY Patil Dental School Pune India .
13 March 2015: An update The role of periodontal surgery . Perio DnYan .
21 January 2015: The importance of corrective periodontal treatment” . Hong Kong Dental Association .
13 December 2014: Diabetes and Periodontal disease Common approach for prevention and management. Beijing China Sunstar International Periodontal Forum .
10 October 2014: “Role of host in the periodontal pathogenesis”). Eastman Dental Institute 2014 –London UK lecture .
19 September 2014: Introduction to periodontal plastic surgery. Thamassat University Bkk Thailand.
13 August 2014: Non-surgical treatment in periodontal regeneration studies: a systematic review. IADR SEA Aug 2014.

HKU Committee Appointments
01 April 2014-31 March 2018: Faculty of Dentistry, Board of the. The teachers who are members of the Faculty and who are full-time employees of the University