馬元博士教學科研部研究助理教授
中藥學
mayuan@hkbu.edu.hk

馬元博士分別於2013，2015，2019年在北京大學取得藥學學士學位，藥物化學碩士學位，藥物化學博士學位。後在香港浸會大學中醫藥學院從事博士後研究工作，並於2022年擔任研究助理教授。
馬博士的研究興趣集中在：1) 小核酸藥物的癌癥診療；2) 中藥現代化靶向治療。
精選出版物Yuan Ma^#, Sifan Yu^#, Shuaijian Ni, Baoxian Zhang, Angela Chun Fai Kung, Jin Gao, Aiping Lu, Ge Zhang*. Targeting strategies for enhancing paclitaxel specificity in chemotherapy. Frontiers in Cell and Developmental Biology, 2021, 9, 626910.
Fangqing Xue^#, Xiao Lin^#, Zhixiong Cai, Xiaolong Liu, Yuan Ma*, Ming Wu*. Doxifluridine-based pharmacosomes delivering miR-122 as tumor microenvironments-activated nanoplatforms for synergistic treatment of hepatocellular carcinoma. Colloids and Surfaces B: Biointerfaces, 2021, 197, 111367. (Co-corresponding author)
Ma Yuan^#, Zhao Wenting^#, Li Yiding, Pan Yufei, Wang Shuhe, Zhu Yuejie, Kong Lingxuan, Guan Zhu, Wang Jiancheng, Zhang Lihe, Yang Zhenjun*. Structural optimization and additional targets identification of antisense oligonucleotide G3139 encapsulated in a neutral cytidinyl-lipid combined with a cationic lipid in vitro and in vivo. Biomaterials, 2019, 197, 182-193.
Yuan Ma^#, Yuejie Zhu#, ChaoWang, Delin Pan, Shuang Liu, Mengyi Yang, Zhangping Xiao, Xiantao Yang, Wenting Zhao, Xinyang Zhou, Yiding Li, Yufei Pan, Jing Sun, Shuhe Wang, Zhu Guan, Lihe Zhang, Zhenjun Yang*. Annealing novel nucleobase-lipids with oligonucleotides or plasmid DNA based on H-bonding or p-p interaction: assemblies and transfections. Biomaterials, 2018, 178, 147-157.
Yuan Ma^#, Shuang Liu#, YusiWang, Yuanhe Zhao, Ye Huang, Lijun Zhong, Zhu Guan, Lihe Zhang, Zhenjun Yang*. Isonucleotide incorporation into middle and terminal siRNA duplexes exhibits high gene silencing efficacy and nuclease resistance. Organic & Biomolecular Chemistry, 2017, 15(24), 5161-5170.
Ye Huang^#, Yuan Ma^#, Yujia Guo, Lang Zou, Hongwei Jin, Lijun Zhong, Yun Wu, Lihe Zhang, Zhenjun Yang*. Exploring directional invasion of serum nuclease into siRNA duplexes by asymmetrical terminal modifications. ChemMedChem, 2014, 9(9), 2111-2119. (Co-first author)