FAN, Xiaodan 樊晓丹Position Professor
Email xfan - _ - cuhk.edu.hk
Phone Number 3943 7930
Fax Number 2603 5188
Address LSB 107
Homepage https://www.sta.cuhk.edu.hk/xfan

Related News
10/06/2021
New Publication in Methods: Detect differentially methylated regions using non-homogeneous hidden Markov model for bisulfite sequencing data, Volume 189, pages 34-43.


Academic BackgroundPh.D. in Statistics (Harvard University)
M.S. in Pattern Recognition & Intelligent Systems (Tsinghua University)
B.E. in Automation (Tsinghua University)
Research InterestComputational Biology & BioinformaticsPattern Recognition and Classification MethodsStatistical Modeling and Computing
Selected Publications In Journals:
Hangjin Jiang, Xingqiu Zhao, Ronald C.W. Ma and Xiaodan Fan (corresponding author). Consistent Screening Procedures in High-dimensional Binary Classification. Statistica Sinica. Accepted.
Yingyu Chen, Chin Kiu Kwok (joint first author), Hangjin Jiang (joint corresponding author) and Xiaodan Fan (joint corresponding author) (2021). Detect differentially methylated regions using non-homogeneous hidden Markov model for bisulfite sequencing data. Methods, Volume 189, pages 34-43. DOI: 10.1016/j.ymeth.2020.09.009
Jiali Yang, Kun Lang, Guangle Zhang, Xiaodan Fan, Yuanyuan Chen, Cong Pian. (2020) SOMM4mC: a second-order Markov model for DNA N4-methylcytosine site prediction in six species. Bioinformatics. 36(14), 4103-4105. DOI: 10.1093/bioinformatics/btaa507. (Web Server: SOMM4mC)
Jie Hu, Huihui Qin and Xiaodan Fan (corresponding author). Can ODE Gene Regulatory Models Neglect Time Lag or Measurement Scaling? Bioinformatics. 36(13):4058-4064. DOI: 10.1093/bioinformatics/btaa268. (R Code: lagODE)
Hangjin Jiang, Hua-Bai Li (joint corresponding author), Xiaodan Fan (joint corresponding author) (2020). Bayesian Revisit of the Relationship between the Total Field Strength and the Volume Density of Interstellar Clouds. The Astrophysical Journal. 890(2):153. DOI: 10.3847/1538-4357/ab672b.
Hangjin Jiang and Xiaodan Fan (corresponding author) (2020). A Consistent Variable Screening Procedure with Family-wise Error Control. Journal of Statistical Computation and Simulation. 90(7):1267-1285. DOI: 10.1080/00949655.2020.1724291. (R Code: HHG-CIS)
Cong Pian, Shanjun Mao, Guangle Zhang, Jin Du, Fei Li, Suet Yi Leung, Xiaodan Fan (corresponding author) (2020). Discovering Cancer-related miRNAs from miRNA-target Interactions by Support Vector Machines. Molecular Therapy: Nucleic Acids. 19:1423-1433. DOI: 10.1016/j.omtn.2020.01.019.
Cong Pian, Guangle Zhang, Fei Li (joint corresponding author) and Xiaodan Fan (joint corresponding author) (2020). MM-6mAPred: Identifying DNA N6-methyladenine Sites Based on Markov Model. Bioinformatics, 36(2):388-392. DOI: 10.1093/bioinformatics/btz556. (Web Server: MM-6mAPred)
Chaojie Wang, Linghao Shen, Han Li, Xiaodan Fan (corresponding author) (2020). Nonparametric Statistical Inference and Imputation for Incomplete Categorical Data. Statistics and Its Interface, 13(1):17-25. DOI: 10.4310/SII.2020.v13.n1.a2. (Software: R-package “MMDai“)
Han Li, Minxuan Xu, Jun S. Liu and Xiaodan Fan (corresponding author) (2020). An Extended Mallows Model for Ranked Data Aggregation. Journal of the American Statistical Association, 115(530):730-746. DOI:10.1080/01621459.2019.1573733. (Software: R-package “ExtMallows“)
Chun Li and Xiaodan Fan (corresponding author) (2019). On Nonparametric Conditional Independence Tests for Continuous Variables. WIREs Computational Statistics, 12(3):e1489. DOI: 10.1002/wics.1489.
Cong Pian, Guangle Zhang, Libin Gao, Xiaodan Fan (joint corresponding author) and Fei Li (joint corresponding author)(2019). miR+Pathway: The Integration and Visualization of miRNA and KEGG Pathways. Briefings in Bioinformatics, 21(2):699-708. DOI:10.1093/bib/bby128. (Web Server: miR-pathway)
Guozhi Jiang, Andrea On Yan Luk, Claudia Ha Ting Tam, Fangying Xie, Bendix Carstensen, Eric Siu Him Lau, Cadmon King Poo Lim, Heung Man Lee, Alex Chi Wai Ng, Maggie Chor Yin Ng, Risa Ozaki, Alice Pik Shan Kong, Chun Chung Chow, Xilin Yang, Hui-yao Lan, Stephen Kwok Wing Tsui, Xiaodan Fan, Cheuk Chun Szeto, Wing Yee So, Juliana C. N. Chan, Ronald C. W. Ma (2019). Progression of Diabetic Kidney Disease and Trajectory of Kidney Function Decline in Chinese Patients with Type 2 Diabetes. Kidney International, 95(1):178-187.
Helen H.N. Yan, Hoi Cheong Siu, Simon Law, Siu Lun Ho, Sarah S.K. Yue, Wai Yin Tsui, Dessy Chan, April S. Chan, Stephanie Ma, Ka On Lam, Sina Bartfeld, Alice H.Y. Man, Bernard C.H. Lee, Annie S.Y. Chan, Jason W.H. Wong, Priscilla S.W. Cheng, Anthony K.W. Chan, Jiangwen Zhang, Jue Shi, Xiaodan Fan, Dora L.W. Kwong, Tak W. Mak, Siu Tsan Yuen, Hans Clevers, Suet Yi Leung (2018). A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening. Cell Stem Cell, 23(6):882-897.e11.
Wei Wang, Tong Liang, Fu Kit Sheong, Xiaodan Fan (joint corresponding author) and Xuhui Huang (joint corresponding author) (2018). An Efficient Bayesian Kinetic Lumping Algorithm to Identify Metastable Conformational States via Gibbs Sampling. The Journal of Chemical Physics, 149(7):072337.
Linghao Shen, Jun Zhu, Shuo-Yen Robert Li and Xiaodan Fan (Corresponding Author) (2017). Detect Differentially Methylated Regions Using Non-homogeneous Hidden Markov Model for Methylation Array Data. Bioinformatics, 33(23):3701-3708. (Software: R-package “DMRMark“)
Zengbing Lu, Man P. Ngan, Ge Lin, David T.W. Yew, Xiaodan Fan, Paul L.R. Andrews and John A. Rudd (2017). Gastric Myoelectric Activity during Cisplatin-Induced Acute and Delayed Emesis Reveals A Temporal Impairment of Slow Waves in Ferrets: Effects Not Reversed by The Glp-1 Receptor Antagonist, Exendin (9-39). Oncotarget, 8(58):98691-98707.
Qing Zhang, Xiaodan Fan (joint first author), Yejun Wang, Ming-an Sun, Jianlin Shao and Dianjing Guo (2017). BPP: A Sequence-based Algorithm for Branch Point Prediction. Bioinformatics, 33(20):3166-3172.
Qin Cao, Christine Anyansi, Xihao Hu, Liangliang Xu, Lei Xiong, Wenshu Tang, Myth T S Mok, Chao Cheng, Xiaodan Fan, Mark Gerstein, Alfred S L Cheng and Kevin Y Yip (2017). Reconstruction of Enhancer–Target Networks in 935 Samples of Human Primary Cells, Tissues and Cell Lines. Nature Genetics, 49(10):1428-1436.
Guozhi Jiang, Claudia H.T. Tam, Andrea O.Y. Luk, Cadmon K. Lim, Xiaodan Fan, Nelson L. S. Tang, Stephen K.W. Tsui, Weichuan Yu, Brian Tomlinson, Yu Huang, Hui Yao Lan, Cheuk-Chun Szeto, Wing Yee So, Juliana C.N. Chan and Ronald C.W. Ma (2017). Estimation of Heritability for Diabetic Complications Based on Genome-wide Association Study in Chinese Population. Diabetologia, 60(1 supp):S174-S174.
Hua-bai Li, Hangjin Jiang, Xiaodan Fan, Qilao Gu and Yapeng Zhang (2017). The Link between Magnetic-field Orientations and Star Formation Rates. Nature Astronomy, 1:0158.
Alexandra M Davis, Xiaodan Fan, Linghao Shen, Paul Robinson, Christopher M Riggs (2017). Improved Radiological Diagnosis of Palmar Osteochondral Disease in The Thoroughbred Racehorse. Equine Veterinary Journal, 49(4):454-460.
Timothy C.T. Ng, Chun Li (joint first author) and Xiaodan Fan (Corresponding Author) (2017). A Fast Algorithm for Reconstructing Multiple Sequence Alignment and Phylogeny Simultaneously. Current Bioinformatics, 12(4):329-348. (C++ Code: FAMAP for Windows/Linux)
Guozhi Jiang, Cheng Hu, Claudia H.T. Tam, Eric S.H. Lau, Ying Wang, Andrea O.Y. Luk, Xilin Yang, Alice P.S. Kong, Janice S.K. Ho, Vincent K.L. Lam, Heung Man Lee, Jie Wang, Rong Zhang, Stephen K.W. Tsui, Maggie C.Y. Ng, Cheuk-Chun Szeto, Weiping Jia, Xiaodan Fan, Wing Yee So, Juliana C.N. Chan and Ronald C.W. Ma (2016). Genetic and Clinical Variables Identify Predictors for Chronic Kidney Disease in Type 2 Diabetes. Kidney International, 89(2):411-420.
Han Li and Xiaodan Fan (Corresponding Author) (2016). A Pivotal Allocation-Based Algorithm for Solving the Label-Switching Problem in Bayesian Mixture Models. Journal of Computational and Graphical Statistics, 25(1):266-283. (R Code: PAR)
Han Li, Chun Li, Jie Hu, Xiaodan Fan (Corresponding Author) (2015). A Resampling Based Clustering Algorithm for Replicated Gene Expression Data. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 12(6):1295-1303. (R Code: RC)
Jie Hu, Zhongying Zhao, Hari Krishna Yalamanchili, Junwen Wang, Kenny Ye and Xiaodan Fan (Corresponding Author) (2015). Bayesian Detection of Embryonic Gene Expression Onset in C. elegans. Annals of Applied Statistics, 9(2):950-968.
Shengtong Han, Raymond K.W. Wong, Thomas C.M. Lee, Shuo-Yen Robert Li and Xiaodan Fan (Corresponding Author) (2014). A Full Bayesian Approach for Boolean Genetic Network Inference. PLoS ONE, 9(12):e115806.
Claudia H.T. Tam, Janice S.K. Ho, Ying Wang, Vincent K.L. Lam, Heung Man Lee, Guozhi Jiang, Eric S.H. Lau, Alice P.S. Kong, Xiaodan Fan, Jean L.F. Woo, Stephen K.W. Tsui, Maggie C.Y. Ng, Wing Yee So, Juliana C.N. Chan, Ronald C. W. Ma (2013). Use of Net Reclassification Improvement (NRI) Method Confirms The Utility of Combined Genetic Risk Score to Predict Type 2 Diabetes. PLoS ONE, 8(12):e83093.
Baojun Chen, Enhao Zheng, Xiaodan Fan, Tong Liang, Qining Wang, Kunlin Wei, and Long Wang (2013). Locomotion Mode Classification Using A Wearable Capacitive Sensing System. IEEE Transactions on Neural Systems and Rehabilitation Engineering. 21(5), 744-755.
Weiqiang Zhou, Hong Yan, Xiaodan Fan and Quan Hao (2013). Prediction of Protein-Protein Interactions Based on Molecular Interface Features and the Support Vector Machine. Current Bioinformatics, 8(1):3-8.
Jin Xu, Qiwei Li, Victor O. K. Li, Shuo-Yen Robert Li and Xiaodan Fan (2013). Improved short adjacent repeat identification using three evolutionary Monte Carlo schemes. International Journal of Data Mining and Bioinformatics. 8(4):462-479.
Tong Liang, Xiaodan Fan (Corresponding Author), Qiwei Li and Shuo-yen Robert Li (2012). Detection of Dispersed Short Tandem Repeats Using Reversible Jump Markov Chain Monte Carlo. Nucleic Acids Research, 40(19):e147. (Matlab Code: Pilot RJMCMC)
Qing Zhang, Xiaodan Fan, Yejun Wang, Mingan Sun, Samuel S. M. Sun and Dianjing Guo (2012) A Model-Based Method for Gene Dependency Measurement. PLoS ONE, 7(7): e40918.
Qiwei Li, Xiaodan Fan (Corresponding Author), Tong Liang, and Shuo-Yen Robert Li (2011). An MCMC Algorithm for Detecting Short Adjacent Repeats Shared by Multiple Sequences. Bioinformatics, 27(13):1772-1779. (C Code: BASARD)
Heung Man Lee, Yi Sui, Hailu Zhao, Kwong Wai Choy, Xiaodan Fan, Wing Yee So, Juliana Chung Ngor Chan and Ronald Ching Wan Ma (2011). The Effects of Uninephrectomy and Accompanied ACEI Treatment on Myocardial Gene Expression. Diabetes, 60(Supp 1):A155.
Xiaodan Fan, Yuan Yuan, and Jun S. Liu (2010). The EM Algorithm and the Rise of Computational Biology. Statistical Science, 25(4):476-491.
Xiang Wan, Can Yang, Qiang Yang, Hong Xue, Xiaodan Fan, Nelson L. S. Tang, and Weichuan Yu (2010). BOOST: A Fast Approach to Detecting Gene-Gene Interactions in Genome-wide Case-Control Studies. American Journal of Human Genetics, 87(3):325-40.
Xiaodan Fan, Saumyadipta Pyne, and Jun S. Liu (2010). Bayesian Meta-Analysis for Identifying Periodically Expressed Genes in Fission Yeast Cell Cycle. The Annals of Applied Statistics, 4(2):988-1013.
Xiaodan Fan and Jun S. Liu (2009). A Bayesian Model for Cross-Study Differential Gene Expression Comment. Journal of the American Statistical Association, 104(488):1314-1318.
Xiaodan Fan, Jun Zhu, Eric E. Schadt, and Jun S. Liu (2007). Statistical Power of Phylo-HMM for Evolutionarily Conserved Element Detection. BMC Bioinformatics, 8(1), 374.
Yingfei Sun, Xiaodan Fan (Joint First Authors), and Yanda Li (2003). Identifying Splicing Sites in Eukaryotic RNA: Support Vector Machine Approach. Computers in Biology and Medicine, 33(1):17-29.
Xiaodan Fan, Yingfei Sun, and Yanda Li (2003). Rapid Development of Real-time Control Systems in C++ Based on RTW. Journal of Tsinghua University, 43(7):895-898.
Yingfei Sun, Xiaodan Fan, and Yanda Li (2003). Secondary Structural Characteristic of Eukaryotic Gene Splicing Sites. Journal of Tsinghua University, 43(3):393-395.
In Conferences:
Guozhi Jiang, Claudia H. T. Tam, Andrea O. Y. Luk, Alice P. S. Kong, Wing Yee So, Juliana C. N. Chan, Ronald C. W. Ma and Xiaodan Fan (corresponding author) (2016). Variable Selection and Prediction of Clinical Outcome with Multiply-Imputed Data via Bayesian Model Averaging. In Proceedings of the IEEE International Conference on Bioinformatics and Biomedicine (BIBM 2016), pages 727-730, Shenzhen, China.
Guozhi Jiang, Claudia HT Tam, Andrea O Luk, Heung Man Lee, Cadmon K.P. Lim, Xiaodan Fan, Si Lok, Ting Fung Chan, Kevin Yuk-Lap Yip, Nelson Tang, Stephen KW Tsui, Weichuan Yu, Brian Tomlinson, Yu Huang, Huiyao Lan, Cheuk-Chun Szeto, Wing Yee So, Juliana C.N. Chan, Ronald C.W. Ma (2016). Genome-Wide Association Study in Chinese Identifies New Susceptibility Loci Associated with Chronic Kidney Disease in Type 2 Diabetes. Diabetes Research and Clinical Practice, 120(Supp 1):S49-S50.
Guozhi Jiang, Eric S. Lau, Ying Wang, Andrea O. Y. Luk, Claudia H. Tam, Janice S. Ho, Vincent K. Lam, Heung M. Lee, Xiaodan Fan, Wing-Yee So, Juliana C. N. Chan, Ronald Ching Wan Ma (2013). Development of Prediction Models under Multiple Imputation for Coronary Heart Disease in Type 2 Diabetes Mellitus. DOI: 10.5220/0315. In Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOINFORMATICS-2013), pages 312-315, Barcelona, Spain.
Han Li and Xiaodan Fan (corresponding author) (2013). A coupled finite mixture model for transcriptional modules discovery. The 59th World Statistics Congress, Hong Kong.
Jin Xu, Albert Y.S. Lam, Victor O. K. Li, Qiwei Li and Xiaodan Fan (corresponding author) (2012). Short Adjacent Repeat Identification Based on Chemical Reaction Optimization. In Proceedings of IEEE Congress on Evolutionary Computation (IEEE CEC 2012), Brisbane, Australia.
Weiqiang Zhou, Hong Yan, Xiaodan Fan, Quan Hao (2011). Prediction of Protein-protein Interactions using Alpha Shape Modeling. In 2011 International Symposium on Computational Models for Life Sciences. AIP Conference Proceedings (CMLS-11), Volume 1371, pages 244-252, Toyama City, Japan.
Qiwei Li, Tong Liang, Xiaodan Fan (corresponding author), Chunhui Xu, Weichang Yu, and Shuo-Yen Robert Li (2010). An Automatic Procedure to Search Highly Repetitive Sequences in Genome as Fluorescence in Situ Hybridization Probes and Its Application on Brachypodium Distachyon. In Proceedings of the 2010 IEEE International Conference on Bioinformatics & Biomedicine, Dec. 2010. pages 563-568, Hong Kong.
Jin Xu, Qiwei Li, Xiaodan Fan, Victor O. K. Li, and Shuo-Yen Robert Li (2010). An Evolutionary Monte Carlo Algorithm for Identifying Short Adjacent Repeats in Multiple Sequences. In Proceedings of the 2010 IEEE International Conference on Bioinformatics & Biomedicine, Dec. 2010. pages 643-648, Hong Kong.
Xiaodan Fan, Xinglai Ji, Rui Jiang (2018). Guest Editorial for Special Section on the Sixth National Conference on Bioinformatics and System Biology of China. IEEE-ACM Transactions On Computational Biology and Bioinformatics, 15(4):1092-1092.
In Reivew:
Shanjun Mao, Xiaodan Fan (joint corresponding author) and Jie Hu (joint corresponding author). Correlation for Tree-Shaped Datasets and Its Bayesian Estimation. Submitted.
Cong Huang, Nianwan Yang, Shuping Wang, Xiaodan Fan, Cong Pian, Jiapeng Luo, Xi Li, Kun Lang, Longsheng Xing, Mingxing Jiang, Wanxue Liu, Wanqiang Qian, Daniel Simberloff, Fanghao Wan, Fei Li. Predicting Insect Invasiveness with Whole-Genome Sequencing Data. Submitted
Hangjin Jiang and Xiaodan Fan (corresponding author). The Two-step Clustering Approach for Learning Metastable States from Molecular Dynamics Data. Submitted.
Hangjin Jiang, Xuhui Huang, Han Li, Wing Hung Wong, Xiaodan Fan (joint corresponding author). CAPT: A New Method for Revealing Free Energy Landscape from MD data. Submitted.
Chaojie Wang, Jin Du and Xiaodan Fan (corresponding author). High-Dimensional Correlation Matrix Estimation for General Continuous Data with Bagging Technique. Submitted.
Jie Hu, Zirui Chen, Wenwei Lin and Xiaodan Fan (corresponding author). Bayesian Detection of Event Spreading Pattern from Multivariate Binary Time Series. Submitted.
Seungyeul Yoo, Quan Chen, Li Wang, Wenhui Wang, Ankur Chakravarthy, Rita Busuttil, Alex Boussioutas, Dan Liu, Junjun She, Tim R. Fenton, Jiangwen Zhang, Xiaodan Fan, Suet-Yi Leung, Jun Zhu. Molecular and cellular heterogeneity of gastric cancer explained by methylation-driven key regulators. Submitted. DOI: 10.1101/2020.01.27.920744.
Cong Pian, Kun Lang, Guangle Zhang, Fei Li (joint corresponding author) and Xiaodan Fan (joint corresponding author). MM-4mCPred: Markov Model for DNA N4-methylcytosine Site Prediction in Six Species. Submitted. (Web Server: MM-4mCPred)
Professional ServicesAssociate Editor, Journal of Computational and Graphical Statistics (2012-07 to Present)
Editorial Board Member, Frontiers in Bioinformatics and Computational Biology (2015-04 to Present)
Guest Editor, IEEE/ACM Transactions on Computational Biology and Bioinformatics (2014-11 to 2018-04)
Referee for Journals: Journal of the American Statistical Association, Annals of Applied Statistics, Journal of Computational and Graphical Statistics, Journal of Statistical Computation and Simulation, Computational Statistics and Data Analysis, IEEE/ACM Trans. on Computational Biology; Bioinformatics, Psychometrika, Technometrics, IEEE Transactions on Signal Processing, PLoS Computational Biology, PLoS One, BMC Bioinformatics, Scientific Reports, etc.
Organizing Committee Member of Conferences: the 4th Institute of Mathematical Statistics Asia Pacific Rim Meeting, CUHK Symposium on Statistics, etc.
Programme Committee Member of Conferences: ICBBB, ITQM, BIBE, ChinaSIP of IEEE, IDASB of BIBM, etc.
TeachingSTAT 3004: Basic Methods in Biomedical Statistics (undergraduate course)
STAT 3011: Workshop on Data Analysis and Statistical Computing (undergraduate course)
STAT 6040: Studies on Selected Topics II (postgraduate course)
STAT 6106: Applied Bayesian Methods (postgraduate course)
My Graduate Students Ph.D. Students:
Li, Dongrong (Major: Statistics, 2020-present )
Zhu, Bencong (Major: Statistics, 2020-present )
Liu, Ran (Major: Statistics, 2019-present )
Zhang, Zhen (Major: Statistics, 2019-present )
Wang, Lijun (Major: Statistics, 2018-present )
Lian, Sheng (Major: Statistics, 2017-2021 )
Mao, Shanjun (Major: Statistics, 2017-2020)
Zhu, Yulin (Major: Statistics, 2016-2020)
Jiang, Hangjin (Major: Statistics, 2015-2018)
Wang, Chaojie (Major: Statistics, 2014-2018)
Shen, Linghao (Major: Information Engineering, 2013-2017)
Hu, Jie (Major: Statistics, 2011-2015)
Li, Chun (Major: Statistics, 2011-2014)
Li, Han (Major: Statistics, 2010-2014)
Jiang, Guozhi (Major: Medical Sciences, co-supervised with Prof. Ronald C.W. Ma, 2010-2013)
Liang, Tong (Major: Information Engineering, co-supervised with Prof. Shuo-Yen Robert Li, 2008-2013)
Han, Shengtong (Major: Statistics, 2009-2012)
M.Phil. Students:
Kwok, Chin Kiu (Major: Statistics, 2016-2018)
Tang, Sheung Ho (Major: Statistics, 2014-2016)
Chen, Zirui (Major: Statistics, 2014-2016)
Lau, Yuk Fai (Major: Statistics, 2013-2015)
Chan, Kwun Cheung (Major: Statistics, 2012-2014)
Lu, Jiayi (Major: Statistics, 2011-2013)
Fung, Ling Hiu (Major: Statistics, 2010-2012)
Li, Qiwei (Major: Information Engineering, co-supervised with Prof. Shuo-Yen Robert Li, 2008-2010)
Wong, Ka Wai (Major: Statistics, 2009-2010)
Research GrantsRGC-GRF Grant; Capacity: Principal Investigator
Title: Consistent Model-free Ultra-high Dimensional Variable Selection for Binary Response
Period: 2020 – 2022
RGC-GRF Grant; Capacity: Principal Investigator
Title: Detection of Differentially Methylated Regions Based on Array or Sequencing Data
Period: 2018 – 2020
RGC-Theme-based Research Scheme; Capacity: Co-Principal Investigator
Title: Gastric Cancer Genomics and Beyond – Moving from Patient Samples to 3D Organoid Cultures for Integrative Genomics Analysis, Drug Sensitivity Assays, Cell Biological Studies and Animal Models
Period: 2016 – 2021
RGC-GRF Grant; Capacity: Principal Investigator
Title: Bayesian Integrative Clustering for Combining Vectorial Data and Network Data
Period: 2016 – 2018
RGC-Theme-based Research Scheme; Capacity: Co-Investigator
Title: An integrated trans-omics approach to diabetic cardio-renal complications: from novel discoveries to personalized medicine
Period: 2014 – 2018
RGC-GRF Grant; Capacity: Principal Investigator
Title: Bayesian Model-based Clustering of the Conformational Space of Biomolecules
Period: 2013 – 2016
UGC-AoE Grant; Capacity: Co-Investigator
Title: Institute of Network Coding
Period: 2010 – 2017
RGC-GRF Grant; Capacity: Principal Investigator
Title: Bayesian Data Integration Approach for Cell-Cycle Gene Network Inference
Period: 2010 – 2012
ITC-ITF; Capacity: Co-Investigator
Title: Developing a Platform to Deliver Personalized Healthcare Using Genotype-based Risk Algorithms to Predict Diabetes and Diabetic Complications
Period: 2010 – 2012
Invited Talks Invited Talks in Conferences/Workshops:
2019-05-29: Statistical Platform for Common Bioinformatics Analyses. Science Faculty Research Day 2019, The Chinese University of Hong Kong, Hong Kong
2019-05-26: An extended Mallows model for ranked data aggregation. The 2019 Hangzhou International Conference on Frontiers of Data Science, organized by the Center for Data Science of Zhejiang University
2018-10-22: Two Problems of Traditional ODE Gene Regulatory Models. The 8th National Conference on Bioinformatics and Systems Biology of China and The 1st (Macao) International Bioinformatics Symposium, organized by Macao University, Macao
2018-07-06: A New Model for Integrating Rank Lists. The Fifth International Biostatistics Symposium, organized by International Biometric Society China and Sun Yat-sen University, China
2018-05-26: Model-based Clustering for Categorical Data with General High Missingness. The Hong Kong Mathematical Society Annual General Meeting 2018, organized by City University of Hong Kong, Hong Kong
2018-05-12: Several Computational Problems in Comparative Methylation Analyses. Quantitative Biology: Model and Inference, organized by Xiamen University, China
2016-10-15: A New Model for Ranked Data Aggregation. Symposium on Intelligent Information Processing (SIIP), organized by Tsinghua University, China
2016-06-30: Pooling partial observations for efficient estimation of the joint distribution. The 4th Institute of Mathematical Statistics Asia Pacific Rim Meeting, organized by Institute of Mathematical Statistics and The Chinese University of Hong Kong, Hong Kong
2016-03-19: An HMM model for the identification of differentially methylated regions. Workshop on Statistical theories, methodologies and applications in high dimensional data analysis and biomedicine, organized by Hong Kong Baptist University, Hong Kong
2015-06-25: Some Thoughts on Probabilistic Data Integration. The Workshop on Youth Statistician Forum: Prospect and Perspective in Statistical Inference and its Application, organized by The AMSS-PolyU JRI and The Hong Kong Polytechnic University
2015-04-19: Model-based inference of protein dynamics based on MD data. The 2015 Joint Statistical Workshop of The Chinese University of Hong Kong and Academia Sinica, organized by The Chinese University of Hong Kong and Academia Sinica
2015-01-22: Bayesian Detection of Gastric Slow Waves from Micro-electrode Data. Workshop Series in Applied Statistics: Statistical Methods in Medical Science, organized by Hang Seng Management College
2014-12-27: Statistical Learning from Large Molecular Dynamics Datasets. Tsinghua-Sanya Workshop on Big Data: Opportunities, Challenges and Innovations, organized by Tsinghua Sanya International Mathematics Forum
2014-12-16: Conformation Clustering based on MD Simulation Data. The Third International Conference on The Interface Between Statistics and Engineering, organized by City University of Hong Kong and Georgia Institute of Technology
2014-06-27: Integrative Clustering for Heterogeneous Data. The Third Joint Biostatistics Symposium, organized by International Biometrical Society-China Region
2013-08-28: Discuss on Statistical Methods in New Frontiers. The 59th World Statistics Congress, Hong Kong
2013-06-16: Elucidation of the energy landscape of biomolecules by model-based clustering. Beijing Computational Science Research Center Workshop on Energy Landscape of Complex System, Beijing, China
2013-05-30: Probabilistic Integrative Clustering. The 1st Chongqing Workshop on Computational and Applied Mathematics (CQWCAM1), Chongqing, China
2013-04-13: Model-based Integration of Heterogeneous Datasets for Clustering. UC Davis Statistical Sciences Symposium 2013: Analysis of Complex and Massive Data, Davis, CA, USA
2012-12-08: Bayesian Approach for Statistical Data Integration. SYSU Guangdong-HK Statistics Symposium, Guangzhou, Guangdong, China
2012-11-10: A Bayesian Approach for Studying Protein Structural Dynamics. The 2012 Annual Conference of Guangdong Association for Applied Statistics, Shenzhen, Guangdong, China
2011-07-17: A Bayesian Clustering Approach for Partitioning the Conformational Space of Biomolecules. The First Wuxi International Statistics Forum, Wuxi, Jiangsu, China
2010-03-27: Multiple Steady States of Gene Networks. ACM-HK Bioinformatics Symposium 2010, HKUST, Hong Kong
2009-06-20: A Bayesian Data Integration Approach for Detecting Periodicity in Cell Cycle Gene Expression Profiles. The 7th International Bioinformatics Workshop. Soochow University, China
2008-12-16: Statistical Data Integration. BGI-CUHK workshop, BGI, Shenzhen, Guangdong, China
Invited Seminar Talks:
2018-10-19: Institute of Space and Earth Information Science, The Chinese University of Hong Kong
2015-10-23: Department of Chemical Pathology, The Chinese University of Hong Kong
2013-03-26: Department of Mathematics, The University of Hong Kong, Hong Kong
2012-11-07: Department of Statistics & Actuarial Science, The University of Hong Kong, Hong Kong
2012-04-17: School of Mathematics and Computational Science, Sun Yat-sen University, Guangzhou, China
2012-03-30: Department of Applied Mathematics, The Hong Kong Polytechnic University, Hong Kong
2011-12-13: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China
2011-12-13: Faculty of Chemical, Environmental & Biological Science & Technology, Dalian University of Technology, China
2011-12-07: School of Mathematical Sciences, Nankai Univeristy, Tianjin, China
2011-12-05: Beijing Engineering Research Center of Intelligent Rehabilitation Engineering, Peking University, Beijing, China
2010-12-10: Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong
2010-04-01: School of Electrical and Electronic Engineering, North China Electric Power University, Beijing, China
2009-11-19: Department of Biology, The Chinese University of Hong Kong
2009-10-08: Department of Manufacturing Engineering and Engineering Management, City University of Hong Kong
2009-07-16: Bioinformatics Division, TNLIST and Automation Department, Tsinghua University, Beijing, China
2009-03-26: Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong
2009-01-21: Bio-X colloquium, The Chinese University of Hong Kong, Hong Kong
2008-10-14: Department of Mathematics, Hong Kong Baptism University
2008-09-16: Journal Club, Department of Biology, The Chinese University of Hong Kong, Hong Kong
2008-08-19: Department of Electronic & Computer Engineering, Hong Kong University of Science and Technology, Hong Kong