Deputy Director

Professor Paul Kay Sheung CHAN
Deputy Director, Stanley Ho Centre for Emerging Infectious Diseases, The Jockey Club School of Public Health and Primary Care, CUHK

Quotable Qualifications

MBBS (HK), MSc (Virology) (Lond),
MD (CUHK), FRCPath, FHKCPath, FHKAM (Pathology)

Biography

Professor Paul KS Chan is Professor of the Department of Microbiology at the Faculty of Medicine of The Chinese University of Hong Kong, and Honorary Consultant in Microbiology for the New Territories East Cluster Hospitals of the Hong Kong Hospital Authority.

Professor Chan is a renowned clinical virologist with special interests in viral epidemiology, pathogenesis and oncogenesis. He has published eight book chapters and more than 200 research papers on clinical virology.

Professor Chan gives imperative advices to the Hong Kong Government. He is the Vice-Chairman of the Scientific Committee on Emerging and Zoonotic Diseases of the Centre for Health Protection; and is a member of the Grant Review Board for the Research Fund for the Control of Infectious Diseases, Human Papillomavirus Vaccine Working Group, Hospital Authority Avian Influenza Working Group, and Examiner Committee of the Hong Kong College of Pathologists. Professor Chan also serves a number of international professional bodies including the Asia-Pacific Advisory Committee on Influenza, Asia-Pacific Advisory Committee on Prevention of Cervical Cancer, GlaxoSmithKline Seasonal Influenza Global Advisory Board, as well as short-term consultant for the World Health Organization on influenza.

Research Interests

• Viral Oncology
  To study the epidemiology and pathogenesis of viral infections that are associated with human cancers. Our present lines of research include the role of novel human herpesviruses (human herpesvirus types six, seven and eight) in the development of human cancers; the molecular mechanisms of human papillomaviruses in causing cervical cancer; the potential clinical applications of using human papillomavirus DNA detection in screening and post-treatment surveillance for cervical cancer.
• Viral Epidemiology
  To study viral infections at a population level. Our recent studies include the disease impact and seasonal variation of rotavirus (the most important cause of diarrhea in infants) and respiratory syncytial virus (the most important cause of lower respiratory tract in young children).
• Opportunistic Viral Infections
  To study the clinical presentations, rapid diagnostic methods and pathogenesis of viral infections that attack immunocompromised patients. Our recent research mainly concentrates on the clinical significance of human herpesvirus six, human herpesvirus seven, human herpesvirus eight and TT virus in bone marrow and renal transplant recipients.

Selected Publications

Journal Articles

• Kwok K, Niendorf S, Lee N, Hung TN, Chan LY, Jacobsen S, Nelson EA, Leung TF, Lai RW, Chan PK, Chan MC. Increased detection of emergent recombinant norovirus GII.P16-GII.2 strains in young adults, Hong Kong, China, 2016-2017. Emerg Infect Dis. 2017 Nov;23(11):1852-1855.
• Chan MC, Hu Y, Chen H, Podkolzin AT, Zaytseva EV, Komano J, Sakon N, Poovorawan Y, Vongpunsawad S, Thanusuwannasak T, Hewitt J, Croucher D, Collins N, Vinjé J, Pang XL, Lee BE, de Graaf M, van Beek J, Vennema H, Koopmans MP, Niendorf S, Poljsak-Prijatelj Global spread of norovirus GII.17 Kawasaki 308,