Kevin Yip
B.Eng., M.Phil. (HKU), Ph.D. (Yale)
Adjunct Professor




Research interests here …






SHB 1006
+852 3943 8418
kevinyip[@]cse.cuhk.edu.hk

Research Areas

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Artificial Intelligence Bioinformatics
Machine Learning
Data and Software Engineering Databases, Data Mining, and Knowledge Management

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Professor (by courtesy), Hong Kong Institute of Diabetes and Obesity (HKIDO), CUHK
Principal Investigator, Hong Kong Bioinformatics Centre, CUHK
Associate Member, Biomedical Engineering Program, CUHK
Member, International Society for Computational Biology
Associate Editor, BMC Bioinformatics



Biography
Prof. Kevin Yip is Adjunct Professor in Department of Computer Science and Engineering at The Chinese University of Hong Kong. His research interests include bioinformatics, computational biology, and genomics, which involve many sub-disciplines of computer science such as algorithm design, data mining, machine learning, and software engineering.



Top Cited Publications
ENCODE Project Consortium: An Integrated Encyclopedia of DNA Elements in the Human Genome. Nature 489(7414):57-74, (2012)
Mark B. Gerstein*$, Zhi John Lu*, Eric L. Van Nostrand*, Chao Cheng*, Bradley I. Arshinoff*, Tao Liu*, Kevin Y. Yip*, Rebecca Robilotto*, Andreas Rechtsteiner*, Kohta Ikegami*, Pedro Alves*, Aurelien Chateigner*, Marc Perry*, Mitzi Morris*, Raymond K. Auerbach*, Xin Feng*, Jing Leng*, Anne Vielle*, Wei Niu*, Kahn Rhrissorrakrai*, Ashish Agarwal, Roger P. Alexander, Galt Barber, Cathleen M. Brdlik, Jennifer Brennan, Jeremy Jean Brouillet, Adrian Carr, Ming-Sin Cheung, Hiram Clawson, Sergio Contrino, Luke O. Dannenberg, Abby F. Dernburg, Arshad Desai, Lindsay Dick, Andrea C. Dose, Jiang Du, Thea Egelhofer, Sevinc Ercan, Ghia Euskirchen, Brent Ewing, Elise A. Feingold, Reto Gassman, Peter J. Good, Phil Green, Francois Gullier, Michelle Gutwein, Mark S. Guyer, Lukas Habegger, Ting Han, Jorja G. Henikoff, Stefan R. Henz, Angie Hinrichs, Heather Holster, Tony Hyman, A. Leo Iniguez, Judith Janette, Morten Jensen, Masaomi Kato, W. James Kent, Ellen Kephart, Vishal Khivansara, Ekta Khurana, John K. Kim, Paulina Kolasinska-Zwierz, Eric C. Lai, Isabel Latorre, Amber Leahey, Suzanna Lewis, Paul Lloyd, Lucas Lochovsky, Rebecca F. Lowdon, Yaniv Lubling, Rachel Lyne, Michael MacCoss, Sebastian D. Mackowiak, Marco Mangone, Sheldon McKay, Desirea Mecenas, Gennifer Merrihew, David M. Miller III, Andrew Muroyama, John I. Murray, Siew-Loon Ooi, Hoang Pham, Taryn Phippen, Elicia A. Preston, Nikolaus Rajewsky, Gunnar Ratsch, Heidi Rosenbaum, Joel Rozowsky, Kim Rutherford, Peter Ruzanov, Mihail Sarov, Rajkumar Sasidharan, Andrea Sboner, Paul Scheid, Eran Segal, Hyunjin Shin, Chong Shou, Frank J. Slack, Cindie Slightam, Richard Smith, William C. Spencer, E.O. Stinson, Scott Taing, Teruaki Takasaki, Dionne Vafeados, Ksenia Voronina, Guilin Wang, Nicole L. Washington, Christina Whittle, Beijing Wu, Koon-Kiu Yan, Georg Zeller, Zheng Zha, Mei Zhong, Xingliang Zhou, modENCODE Consortium, Julie Ahringer$, Susan Strome$, Kristin C. Gunsalus$, Gos Micklem$, X. Shirley Liu$, Valerie Reinke$, Stuart K. Kim$, LaDeana W. Hillier$, Steven Henikoff$, Fabio Piano$, Michael Snyder$, Lincoln Stein$, Jason D. Lieb$ and Robert H. Waterston$: Integrative Analysis of the Caenorhabditis elegans Genome by the modENCODE Project. Science 330(6012):1775-1787, (2010)
Kevin Y. Yip, Chao Cheng, Nitin Bhardwaj, James B. Brown, Jing Leng, Anshul Kundaje, Joel Rozowsky, Ewan Birney, Peter Bickel, Michael Snyder and Mark Gerstein: Classification of Human Genomic Regions based on Experimentally-determined Binding Sites of More Than 100 Transcription-related Factors. Genome Biology 13(9):R48, (2012)
Shaoke Lou*, Heung-Man Lee*, Hao Qin, Jing-Woei Li, Zhibo Gao, Xin Liu, Landon L. Chan, Vincent K. L. Lam, Wing-Yee So, Ying Wang, Si Lok, Jun Wang, Ronald C. W. Ma, Stephen Kwok-Wing Tsui, Juliana C. N. Chan$, Ting-Fung Chan$ and Kevin Y. Yip$: Whole-Genome Bisulfite Sequencing of Multiple Individuals Reveals Complementary Roles of Promoter and Gene Body Methylation in Transcriptional Regulation. Genome Biology 15(7):408, (2014)
Qin Cao, Christine Anyansi, Xihao Hu, Liangliang Xu, Lei Xiong, Wenshu Tang, Myth T S Mok, Chao Cheng, Xiaodan Fan, Mark Gerstein, Alfred S L Cheng and Kevin Y Yip: Reconstruction of Enhancer-Target Networks in 935 Samples of Human Primary Cells, Tissues and Cell Lines. Nature Genetics 49(10):1428-1436, (2017)


Recent Publications
Alexander Xi Fu*, Kathy Nga-Chu Lui*, Clara Sze-Man Tang, Ray Kit Ng, Frank Pui-Ling Lai, Sin-Ting Lau, Zhixin Li, Maria-Mercè Garcia-Barcelo, Pak-Chung Sham, Paul Kwong-Hang Tam$, Elly Sau-Wai Ngan$ and Kevin Y. Yip$: Whole-Genome Analysis of Noncoding Genetic Variations Identifies Multi-Scale Regulatory Element Perturbations Associated with Hirschsprung Disease. Genome Research 30(11):1618-1632, (2020)
Qin Cao*, Zhenghao Zhang*, Alexander Xi Fu, Qiong Wu, Tin-Lap Lee, Eric Lo, Alfred S. L. Cheng, Chao Cheng, Danny Leung and Kevin Y. Yip: A Unified Framework for Integrative Study of Heterogeneous Gene Regulatory Mechanisms. Nature Machine Intelligence 2(8):447-456, (2020)
Michal Levy-Sakin*, Steven Pastor*, Yulia Mostovoy*, Le Li*, Alden KY Leung*, Jennifer McCaffrey*, Eleanor Young, Ernest T Lam, Alex R Hastie, Karen HY Wong, Claire YL Chung, Walfred Ma, Justin Sibert, Ramakrishnan Rajagopalan, Nana Jin, Eugene YC Chow, Catherine Chu, Annie Poon, Chin Lin, Ahmed Naguib, Wei-Ping Wang, Han Cao, Ting-Fung Chan$, Kevin Y Yip$, Ming Xiao$ and Pui-Yan Kwok$: Genome Maps Across 26 Human Populations Reveal Population-specific Patterns of Structural Variation. Nature Communications 10(1):1025, (2019)
Le Li*, Yuwei Gao*, Qiong Wu, Alfred S. L. Cheng$ and Kevin Y. Yip$: New Guidelines for DNA Methylome Studies Regarding 5-hydroxymethylcytosine for Understanding Transcriptional Regulation. Nature Communications 10(1):1025, (2019)
Lei Xiong, Feng Wu, Qiong Wu, Liangliang Xu, Otto K. Cheung, Wei Kang, Myth T. Mok, Lemuel L. Szeto, Cheuk-Yin Lun, Raymond W. Lung, Jinglin Zhang, Ken H. Yu, Sau-Dan Lee, Guangcun Huang, Chiou-Miin Wang, Joseph Liu, Zhuo Yu, Dae-Yeul Yu, Bo Feng, Jian-Liang Chou, Wan-Hong Huang, Yue-Sun Cheung, Paul B. Lai, Patrick Tan, Nathalie Wong, Michael W. Chan, Tim H. Huang, Kevin Y. Yip$, Alfred S. Cheng$ and Ka-Fai To$: Aberrant Enhancer Hypomethylation Contributes to Hepatic Carcinogenesis through Global Transcriptional Reprogramming. Nature Communications 10(1):335, (2019)


Achievements and Awards
2019 Outstanding Fellow, Faculty of Engineering, CUHK (https://www.erg.cuhk.edu.hk/erg/Recognitions)
2019 Young Researcher Award, CUHK
2019 Exemplary Service Award, Department of Computer Science and Engineering, CUHK
2017 Exemplary Service Award, Department of Computer Science and Engineering, CUHK
2015 Exemplary Service Award, Faculty of Engineering, CUHK