Publication in policy or professional journal
香港中文大学研究人员 ( 现职)
| 袁璟教授 (影像及介入放射学系) |
| Professor Ann Dorothy KING (影像及介入放射学系) |
| Professor Kunwar Suryaveer Singh BHATIA (影像及介入放射学系) |
| 区皓智教授 (影像及介入放射学系) |
| 黄乐瑶小姐 (影像及介入放射学系) |
| 马碧如教授 (肿瘤学系) |
| 罗敬匡先生 (影像及介入放射学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1007/s00405-016-4333-6 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/0WOS source URL
其它资讯
摘要Our study aimed to identify diffusion-weighted imaging (DWI) parameters obtained from primary nasopharyngeal carcinoma (NPC) at initial presentation, that can predict patients at risk of distant metastases. One hundred and sixty-four patients underwent pretreatment magnetic resonance imaging and DWI. The apparent diffusion coefficient (ADC)mean, ADCskewness, and ADCkurtosis were obtained by histogram analysis. Univariate and multivariate analyses of these ADC parameters together with primary volume (PV), nodal volume (NV), T stage, N stage and presence of locoregional relapse (LRR) were compared between patients with distant metastases (DM+) and patients without distant metastases (DM?) at 5 years using logistic regression. Twenty-eight out of 164 patients (17.1 %) were DM+ (2.5–6http://aims.cuhk.edu.hk/converis/portal/Publication/0 months) and 136/164 patients were DM? (61.2–119.4 months). Compared to DM? patients, the primary tumour of DM+ patients showed significantly lower ADCskewness (ADC values with the greatest frequency were higher) (p = http://aims.cuhk.edu.hk/converis/portal/Publication/0.http://aims.cuhk.edu.hk/converis/portal/Publication/041), and higher PV (p = http://aims.cuhk.edu.hk/converis/portal/Publication/0.http://aims.cuhk.edu.hk/converis/portal/Publication/022), NV (p < http://aims.cuhk.edu.hk/converis/portal/Publication/0.http://aims.cuhk.edu.hk/converis/portal/Publication/01), T stage (p = http://aims.cuhk.edu.hk/converis/portal/Publication/0.http://aims.cuhk.edu.hk/converis/portal/Publication/023), N stage (p < http://aims.cuhk.edu.hk/converis/portal/Publication/0.http://aims.cuhk.edu.hk/converis/portal/Publication/01) and LRR (p < http://aims.cuhk.edu.hk/converis/portal/Publication/0.http://aims.cuhk.edu.hk/converis/portal/Publication/01). On multivariate analysis the ADCskewness was no longer significant (p = http://aims.cuhk.edu.hk/converis/portal/Publication/0.12http://aims.cuhk.edu.hk/converis/portal/Publication/0) and only NV and LRR were independent predictors for DM+ (p = http://aims.cuhk.edu.hk/converis/portal/Publication/0.http://aims.cuhk.edu.hk/converis/portal/Publication/023 and http://aims.cuhk.edu.hk/converis/portal/Publication/0.http://aims.cuhk.edu.hk/converis/portal/Publication/021, respectively). DWI showed that compared to DM? patients, DM+ patients had a significantly lower primary tumour ADCskewness, but at initial presentation NV was the only independent predictor of DM.
出版社接受日期http://aims.cuhk.edu.hk/converis/portal/Publication/03.1http://aims.cuhk.edu.hk/converis/portal/Publication/0.2http://aims.cuhk.edu.hk/converis/portal/Publication/016
着者Qi-Yong Ai, Ann D. King, Benjamin King Hong Law, David Ka-Wai Yeung, Kunwar S. Bhatia, Jing Yuan, Anil T. Ahuja, Lok Yiu Sheila Wong, Brigette B. Ma, Frankie Kwok Fai Mo, Michael K. M. Kam
期刊名称European Archives of Oto-Rhino-Laryngology
出版年份2http://aims.cuhk.edu.hk/converis/portal/Publication/017
月份2
卷号274
期次2
出版社Springer
页次1http://aims.cuhk.edu.hk/converis/portal/Publication/045 - 1http://aims.cuhk.edu.hk/converis/portal/Publication/051
国际标準期刊号http://aims.cuhk.edu.hk/converis/portal/Publication/0937-4477
电子国际标準期刊号1434-4726
语言英式英语
关键词Diffusion-weighted imaging, Distant metastases, Magnetic resonance imaging, Nasopharyngeal carcinoma
