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Danshen: An overview of its chemistry, pharmacology, pharmacokinetics, and clinical use (2005)_香港中文大

香港中文大学 辅仁网/2017-06-27

Danshen: An overview of its chemistry, pharmacology, pharmacokinetics, and clinical use
Publication in refereed journal


香港中文大学研究人员 ( 现职)
周柽森教授 (药剂学院)
左中教授 (药剂学院)
周立敏博士 (药剂学院)


全文


引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/688WOS source URL

其它资讯

摘要Danshen, the dried root of Salvia miltiorrhiza, has been widely used in China and, to a lesser extent, in Japan, the United States, and other European countries for the treatment of cardiovascular and cerebrovascular diseases. In China, the specific clinical use is angina pectoris, hyperlipidemia, and acute ischemic stroke. The current review covers its traditional uses, chemical constituents, phor macological activities, pharmacokinetics, clinical applications, and potential herb-drug interactions based on information obtained in both the English and Chinese literature. Although numerous clinical trials have demonstrated that certain Danshen products in China are effective and safe for the treatment of cardiovascular diseases, most of these lack sufficient quality Therefore, large randomized clinical trials and further scientific research to determine its mechanism of actions will be necessary to ensure the safety, effectiveness, and better understanding of its action.

着者Zhou LM, Zuo Z, Chow MSS
期刊名称Journal of Clinical Pharmacology
出版年份2005
月份12
日期1
卷号45
期次12
出版社SAGE PUBLICATIONS INC
页次1345 - 1359
国际标準期刊号0091-2700
电子国际标準期刊号1552-4604
语言英式英语

关键词Danshen; danshensu; Salvia miltiorrhiza; salvianolic acid B; tanshinone IIA
Web of Science 学科类别Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY

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