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Two different glycemic control ways applied to treat severe acute pancreatitis (2017)_香港中文大学

香港中文大学 辅仁网/2017-06-25

Two different glycemic control ways applied to treat severe acute pancreatitis
Publication in refereed journal


香港中文大学研究人员 ( 现职)
车锡英教授 (那打素护理学院)


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摘要Objective: To determine the optimum blood glucose target values between two classic glycemic control
goals and compare their efficacy and safety in patients with Severe Acute Pancreatitis (SAP).
Methods: 112 SAP patients included in the study were randomly divided into two groups: group A for a
blood sugar control target value of 7.8-10 mmol/L and group B for a blood glucose control target value
of 6.1-8.3 mmol/L. The glycemic control parameters, prognostic parameters and adverse events during
glycemic control were compared.
Results: Group A achieved glycemic control goals more quickly than group B, and had significantly less
severe hypoglycemic events and glucose treatment events (p<0.05). No significant differences in
moderate/severe malnutrition rates, the incidence of infection, MODS incidence, the average ICU stay,
28 day mortality, and hyperglycemic parameters were observed (p>0.05) between the two groups.
Conclusion: Glycemic control target of 7.8-10 mmol/L can reduce the risk of hypoglycemia in patients
with SAP and is achieved faster and more safely than a glycemic control target of 6.1-8.3 mmol/L.

出版社接受日期02.02.2017
着者Qin Y.L., Shi Z.Y., Tang S.Y., Liu Y.H., Zhu Y.M., Zhou X., Jiang B., Liu M.H., Chair S.Y.
期刊名称Biomedical Research
出版年份2017
卷号28
期次9
页次4009 - 4012
国际标準期刊号0970-938X
语言英式英语

关键词Glycemic control goal, SAP, Hypoglycemia, Prognosis

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