Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 郑健芳教授 (那打素护理学院) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1016/j.ejon.2006.03.004 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/9WOS source URL
其它资讯
摘要Oral mucositis associated with cancer therapy often has devastating impact on patients' quality of life (QoL), affecting multiple spheres of daily and psychosocial. functioning. This descriptive cross-sectional study aimed at describing the severity and distress of oral mucositis, as well as QoL of Hong Kong Chinese patients treated with cancer therapy, and identifying the extent to which oral mucositis correlated with QoL. A convenience sample of 38 in-patients and 50 out-patients with solid tumors and during the peak phase of oral mucositis was recruited. The severity and distress of oral mucositis were assessed by a 4-point rating scale ranging from 1 (mild) to 4 (very severe) and 5-point rating scale ranging from 0 (not at all) to 4 (very much), respectively. The QoL was assessed by the Chinese version Functional Assessment of Cancer Therapy-General questionnaires (Ch-FACT-G). The mean +/- SD severity and distress scores of oral mucositis were 2.1 +/- 0.http://aims.cuhk.edu.hk/converis/portal/Publication/9 and 1.6 +/- 1.2, respectively. The total mean +/- SD scores of physical, social/family, emotional, and functional subscates of the Ch-FACT-G were 15.1 +/- 5.http://aims.cuhk.edu.hk/converis/portal/Publication/9, 16.3 +/- 4.1, 15.7 +/- 4.5, and 11.http://aims.cuhk.edu.hk/converis/portal/Publication/9 +/- 6.8 separately. The physical subscales of the Ch-FACT-G significantly correlated with the severity (r = 0.305, P < 0.01) and the distress (r = 0.355, P < 0.01) of oral. mucositis. A significantly mild positive correlation was also found between the emotional subscale of the Ch-FACT-G and the severity of oral mucositis (r = 0.314, P < 0.01). Subjects receiving radiotherapy reported a tower range of total social/family, emotional, and functional subscale scores than that of those receiving chemotherapy or chemo-radiotherapy, but these differences were not statistically significant (P > 0.05). In conclusion, QoL, especially the functional sphere, was compromised for patients with oral mucositis. The data also support the correlations between oral mucositis and the physical sphere of QoL, as well as oral mucositis and the emotional sphere of QoL. (c) 2006 Elsevier Ltd. All rights reserved.
着者Cheng KKF
期刊名称European Journal of Oncology Nursing
出版年份2007
月份2
日期1
卷号11
期次1
出版社ELSEVIER SCI LTD
页次36 - 42
国际标準期刊号1462-388http://aims.cuhk.edu.hk/converis/portal/Publication/9
电子国际标準期刊号1532-2122
语言英式英语
关键词chemotherapy; oral mucositis; quality of life; radiotherapy
Web of Science 学科类别Nursing; NURSING, SCI; NURSING, SSCI; Oncology; ONCOLOGY
