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Characterization of the human 36-kDa carboxyl terminal LIM domain protein (hCLIM1) (1999)_香港中文大学

香港中文大学 辅仁网/2017-06-25

Characterization of the human 36-kDa carboxyl terminal LIM domain protein (hCLIM1)
Publication in refereed journal


香港中文大学研究人员 ( 现职)
韦妙宜教授 (那打素护理学院)
李卓予教授 (生物医学学院)
冯国培教授 (生物医学学院)
徐国荣教授 (生物医学学院)
倪世明教授 (生命科学学院)


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Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/39WOS source URL

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摘要We characterized a human cDNA clone encoding a 36-kDa carboxyl terminal LIM domain protein with a PDZ domain at the amino terminal. This full-length cDNA clone has a predicted open reading frame (ORF) of 329 amino-acid residues. The ORF of this cDNA encodes the human homolog of rat CLP36, and the putative protein is named human 36-kDa carboxyl terminal LIM domain protein (hCLIM1, nomenclature approved by the HUGO/GDB Nomenclature Committee). The hCLIM1 probe was used to hybridize with poly(A)(+) RNA of various human tissues. Strong signals were detected in heart and skeletal muscle; moderate signals were detected in spleen, small intestine, colon, placenta, and lung; weaker levels were detected in liver, thymus, kidney, prostate, and pancreas; and no observable signals were detected in brain, testis, ovary, and peripheral blood leukocytes. The hCLIM1 gene was studied by fluorescence in situ hybridization (FISH), somatic cell hybrid analysis, and radiation hybrid mapping, and it is located at the human chromosome 10q26. J. Cell. Biochem. 72:279-285, 1999. (C) 1999 Wiley-Liss, Inc.

着者Kotaka M, Ngai SM, Carcia-Barcelo M, Tsui SKW, Fung KP, Lee CY, Waye MMY
期刊名称Journal of Cellular Biochemistry
出版年份1999
月份2
日期1
卷号72
期次2
出版社WILEY-LISS
页次279 - 285
国际标準期刊号0730-2312
电子国际标準期刊号1097-4644
语言英式英语

关键词10q26; CLP36; heart cDNA; PDZ domain; radiation hybrid mapping; zinc finger protein
Web of Science 学科类别Biochemistry & Molecular Biology; BIOCHEMISTRY & MOLECULAR BIOLOGY; Cell Biology; CELL BIOLOGY

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