Developmental regulation of http://aims.cuhk.edu.hk/converis/portal/Publication/14-3-3 epsilon isoform in rat heart
Publication in refereed journal


香港中文大学研究人员 ( 现职)

韦妙宜教授 (那打素护理学院)

李卓予教授 (生物医学学院)

冯国培教授 (生物医学学院)

徐国荣教授 (生物医学学院)

倪世明教授 (生命科学学院)

全文

数位物件识别号 (DOI) http://dx.doi.org/10.1002/(SICI)1097-4644(19980201)68:2<195::AID-JCB6>3.0.CO;2-Q

引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/14WOS source URL

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摘要Human heart cDNA sequencing yielded a cDNA clone that is similar in DNA and amino acid sequences to that of mouse http://aims.cuhk.edu.hk/converis/portal/Publication/14-3-3 epsilon isoform. The 6xHis-tagged Hhttp://aims.cuhk.edu.hk/converis/portal/Publication/1433 epsilon recombinant protein was expressed in Escherichia coli and its size was approximately 30 kDa. From Northern blot results with human multiple tissues, human skeletal muscle was found to have the highest level of hi 433 epsilon mRNA expression, whereas Northern blots of human cancer cell lines detected the highest mRNA level of hhttp://aims.cuhk.edu.hk/converis/portal/Publication/1433 epsilon in colorectal adenocarcinoma SW480. The protein expression level of hhttp://aims.cuhk.edu.hk/converis/portal/Publication/1433 epsilon and Raf-1 is found to be regulated coordinately during rat heart development, and their protein expression was highest from http://aims.cuhk.edu.hk/converis/portal/Publication/14.5 to 16.5 days postcoitum. (C) 1998 Wiley-Liss, Inc.

着者Luk SCW, Ngai SM, Tsui SKW, Chan KK, Fung KP, Lee CY, Waye MMY
期刊名称Journal of Cellular Biochemistry
出版年份1998
月份2
日期1
卷号68
期次2
出版社WILEY-LISS
页次195 - 199
国际标準期刊号0730-2312
电子国际标準期刊号1097-4644
语言英式英语

关键词http://aims.cuhk.edu.hk/converis/portal/Publication/14-3-3 protein; developmental regulation; heart development; Raf-1
Web of Science 学科类别Biochemistry & Molecular Biology; BIOCHEMISTRY & MOLECULAR BIOLOGY; Cell Biology; CELL BIOLOGY