Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 李卓予教授 (生物医学学院) |
| 韦妙宜教授 (那打素护理学院) |
| 冯国培教授 (生物医学学院) |
| 徐国荣教授 (生物医学学院) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1006/geno.1995.9874 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/40WOS source URL
其它资讯
摘要Single-pass sequencing of randomly selected cDNA clones to generate expressed sequence tags (ESTs) has been widely used to identify novel genes and to study gene expression in a variety of tissues. We have generated 2244 ESTs from a human fetal heart library (GenBank Accession Nos. R30692-30774 and R56965-58824), which we present in this report. Of these, 51.7% showed no homology to known genes or were similar only to other ESTs, while 48.4% demonstrated homology to known transcripts. A total of 764 ESTs corresponding to known genes were used to study gene expression patterns in the fetal heart and to analyze differences in these patterns from those observed in the adult heart. These analyses demonstrate the utility of ESTs and sequence-tagged clones in comparative studies of gene expression in the cardiovascular system, and they reveal that differential gene expression underlies the structural and functional characteristics of the developing heart. (C) 1995 Academic Press, Inc.
着者HWANG DM, FUNG YW, WANG RX, LAURENSSEN CM, NG SH, LAM WY, TSUI KW, FUNG KP, WAYE M, LEE CY, LIEW CC
期刊名称GENOMICS
出版年份1995
月份11
日期20
卷号30
期次2
出版社ACADEMIC PRESS INC ELSEVIER SCIENCE
页次293 - 298
国际标準期刊号0888-7543
电子国际标準期刊号1089-8646
语言英式英语
Web of Science 学科类别Biotechnology & Applied Microbiology; BIOTECHNOLOGY & APPLIED MICROBIOLOGY; Genetics & Heredity; GENETICS & HEREDITY
